hydroxyl radical has been researched along with Nerve Degeneration in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.00) | 18.7374 |
| 1990's | 12 (48.00) | 18.2507 |
| 2000's | 10 (40.00) | 29.6817 |
| 2010's | 2 (8.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ambrosi, P; Behr, GA; da Rocha, JB; Gelain, DP; Kolling, EA; Moreira, JC; Pires, AS; Rybarczyk-Filho, JL; Terra, SR; Zeidán-Chuliá, F | 1 |
| Górska, A; Gołembiowska, K; Noworyta-Sokołowska, K | 1 |
| Barman, PK; Borah, A; Mohanakumar, KP; Pandey, M; Usha, R; Varghese, M | 1 |
| Ariga, H; Inden, M; Kitamura, Y; Shibaike, T; Taira, T; Takata, K; Tamaki, A; Taniguchi, T; Yamamoto, A; Yanagida, T; Yasui, H | 1 |
| Arriagada, C; Cardenas, S; Castañeda, P; Caviedes, P; Couve, E; Graumann, R; Herrero, MT; Martinez-Alvarado, P; Olea-Azar, C; Paris, I; Perez-Pastene, C; Sanchez de las Matas, MJ; Segura-Aguilar, J | 1 |
| Ali, S; Chun, W; Hjelle, OP; Jhoo, WK; Kim, DS; Kim, HC; Kim, WK; Ko, KH; Lim, YK; Ottersen, OP; Shin, CY; Shin, EJ; Suh, SK | 1 |
| Mohanakumar, KP; Saravanan, KS; Senthilkumar, KS; Sindhu, KM | 1 |
| Deng, YL; Liu, XQ; Qing, H; Wang, R; Zheng, XL | 1 |
| Cohen, G | 1 |
| Gutteridge, JM | 1 |
| Chiueh, CC; Krishna, G; Mohanakumar, KP; Murphy, DL; Obata, T; Sternberger, LM; Wu, RM | 1 |
| Dykens, JA | 1 |
| Asanuma, M; Edamatsu, R; Kohno, M; Mizukawa, K; Mori, A; Ogawa, N | 1 |
| Chiueh, CC; Miyake, H; Peng, MT | 1 |
| Kondo, T | 1 |
| Almås, B; Flatmark, T; Haavik, J | 1 |
| Jiang, DH; Lan, J | 1 |
| Chiueh, CC; Khaldi, A; Mohanakumar, KP; Rauhala, P | 1 |
| Andrus, PK; Gleason, DD; Hall, ED; Smith, SL | 1 |
| Ferger, B; Kuschinsky, K; Seitz, G; Spratt, C; Teismann, P | 1 |
| Kubota, S; Obata, T; Yamanaka, Y | 1 |
| Kinemuchi, H; Obata, T; Oreland, L; Yamanaka, Y | 1 |
| Burke, WJ; Li, SW; Lin, TS; Minteer, S | 1 |
| Huang, M; Li, Q; Liu, W; Wu, CF | 1 |
| Ang, LC; Richardson, JS; Subbarao, KV | 1 |
4 review(s) available for hydroxyl radical and Nerve Degeneration
| Article | Year |
|---|---|
Hydroxyl radicals, iron, oxidative stress, and neurodegeneration.
Topics: Abetalipoproteinemia; Alzheimer Disease; Animals; Antioxidants; Brain; Brain Diseases; Brain Injuries; Brain Ischemia; Cell Membrane; Ferritins; Hemosiderin; Humans; Hydroxyl Radical; Iron; Nerve Degeneration; Oxidative Stress; Parkinson Disease | 1994 |
In vivo generation of hydroxyl radicals and MPTP-induced dopaminergic toxicity in the basal ganglia.
Topics: Animals; Antioxidants; Basal Ganglia; Corpus Striatum; Dopamine; Free Radical Scavengers; Free Radicals; Humans; Hydroxyl Radical; Melanins; MPTP Poisoning; Nerve Degeneration; Parkinson Disease; Rats; Salicylates; Selegiline; Substantia Nigra | 1994 |
Parkinson's disease and free radicals. Mechanism of neurodegeneration and neuroprotection.
Topics: Corpus Striatum; Deferoxamine; Free Radicals; Humans; Hydroxyl Radical; Nerve Degeneration; Neurons; Parkinson Disease | 1996 |
Desferrioxamine and vitamin E protect against iron and MPTP-induced neurodegeneration in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Diseases; Corpus Striatum; Deferoxamine; Dopamine; Female; Glutathione; Glutathione Disulfide; Hydroxyl Radical; Iron; Lipid Peroxides; Male; Mice; Nerve Degeneration; Osmolar Concentration; Vitamin E | 1997 |
21 other study(ies) available for hydroxyl radical and Nerve Degeneration
| Article | Year |
|---|---|
Major components of energy drinks (caffeine, taurine, and guarana) exert cytotoxic effects on human neuronal SH-SY5Y cells by decreasing reactive oxygen species production.
Topics: Antioxidants; Caffeine; Catalase; Cell Count; Cell Death; Cell Line, Tumor; Cell Shape; Cell Survival; Energy Drinks; Free Radical Scavengers; Humans; Hydroxyl Radical; Intracellular Space; Lipid Metabolism; Models, Biological; Nerve Degeneration; Neurites; Neurons; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Paullinia; Reactive Oxygen Species; Superoxide Dismutase; Taurine | 2013 |
LPS-induced oxidative stress and inflammatory reaction in the rat striatum.
Topics: Adenosine; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Glutamic Acid; Hydroxyl Radical; Inflammation; Injections, Intraperitoneal; Lipopolysaccharides; Microinjections; Nerve Degeneration; Neuroglia; Oxidative Stress | 2013 |
Striatal dopamine level contributes to hydroxyl radical generation and subsequent neurodegeneration in the striatum in 3-nitropropionic acid-induced Huntington's disease in rats.
Topics: Animals; Convulsants; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Huntington Disease; Hydroxyl Radical; Lameness, Animal; Levodopa; Male; Mitochondria; Nerve Degeneration; Neurotoxins; Nitro Compounds; Oxidative Phosphorylation; Oxidative Stress; Propionates; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase | 2009 |
Neuroprotective effect of the antiparkinsonian drug pramipexole against nigrostriatal dopaminergic degeneration in rotenone-treated mice.
Topics: alpha-Synuclein; Animals; Antiparkinson Agents; Apoptosis; Benzothiazoles; Cell Line, Tumor; Corpus Striatum; Cytochromes c; Dopamine; Dose-Response Relationship, Drug; Humans; Hydrogen Peroxide; Hydroxyl Radical; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neural Pathways; Neurotoxins; Oxidative Stress; Parkinsonian Disorders; Pramipexole; Proto-Oncogene Proteins c-bcl-2; Rotenone; Substantia Nigra; Uncoupling Agents | 2009 |
On the neurotoxicity mechanism of leukoaminochrome o-semiquinone radical derived from dopamine oxidation: mitochondria damage, necrosis, and hydroxyl radical formation.
Topics: Animals; Benzoquinones; Cell Line; Dopamine; Hydroxyl Radical; Membrane Potentials; Mitochondria; Necrosis; Nerve Degeneration; Neurons; Neurotoxins; Oxidation-Reduction; Rats; Rats, Inbred F344; Substantia Nigra; Superoxide Dismutase | 2004 |
Ascorbate attenuates trimethyltin-induced oxidative burden and neuronal degeneration in the rat hippocampus by maintaining glutathione homeostasis.
Topics: Animals; Antioxidants; Ascorbic Acid; Astrocytes; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Glial Fibrillary Acidic Protein; Glutathione; Glutathione Disulfide; Hippocampus; Homeostasis; Hydroxyl Radical; Malondialdehyde; Nerve Degeneration; Neurons; Oxidative Stress; Rats; Rats, Sprague-Dawley; Trimethyltin Compounds | 2005 |
L-deprenyl protects against rotenone-induced, oxidative stress-mediated dopaminergic neurodegeneration in rats.
Topics: Amphetamine; Animals; Catalase; Disease Models, Animal; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Electron Transport Complex I; Hydroxyl Radical; Male; Nerve Degeneration; Neurons; Neuroprotective Agents; Oxidative Stress; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Rotenone; Selegiline; Substantia Nigra; Superoxide Dismutase; Tyrosine 3-Monooxygenase; Uncoupling Agents; Up-Regulation | 2006 |
Iron contributes to the formation of catechol isoquinolines and oxidative toxicity induced by overdose dopamine in dopaminergic SH-SY5Y cells.
Topics: Apoptosis; Catechols; Cell Line, Tumor; Cell Survival; Dopamine; Dose-Response Relationship, Drug; Humans; Hydroxyl Radical; Iron; Iron Metabolism Disorders; Isoquinolines; Malondialdehyde; Models, Biological; Nerve Degeneration; Neurons; Neurotoxins; Oxidative Stress; Parkinson Disease; Salsoline Alkaloids; Up-Regulation | 2008 |
The pathobiology of Parkinson's disease: biochemical aspects of dopamine neuron senescence.
Topics: Animals; Brain; Catalase; Catecholamines; Dopamine; Glutathione Peroxidase; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Levodopa; Monoamine Oxidase; Nerve Degeneration; Neurons; Parkinson Disease; Rats; Selegiline; Superoxide Dismutase; Superoxides | 1983 |
Isolated cerebral and cerebellar mitochondria produce free radicals when exposed to elevated CA2+ and Na+: implications for neurodegeneration.
Topics: Adenosine Diphosphate; Animals; Calcium; Cell Hypoxia; Cerebellum; Cerebral Cortex; Electron Spin Resonance Spectroscopy; Electron Transport; Free Radicals; Humans; Hydroxyl Radical; Male; Mitochondria; NAD(P)H Dehydrogenase (Quinone); Nerve Degeneration; Neurons; Nitrogen Oxides; Parkinson Disease; Pyridines; Rats; Rats, Wistar; Sodium; Spin Labels | 1994 |
Degeneration of dopaminergic neurons and free radicals. Possible participation of levodopa.
Topics: Animals; Corpus Striatum; Culture Techniques; Dopamine; Electron Spin Resonance Spectroscopy; Free Radicals; Hydroxides; Hydroxyl Radical; Levodopa; Male; Mice; Mice, Inbred ICR; Microscopy, Electron; Nerve Degeneration; Receptors, Dopamine; Subcellular Fractions; Substantia Nigra; Superoxides; Thiobarbiturates | 1993 |
Role of dopamine autoxidation, hydroxyl radical generation, and calcium overload in underlying mechanisms involved in MPTP-induced parkinsonism.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Calcium; Calcium Channels; Cell Death; Corpus Striatum; Dopamine; Free Radicals; Hydroxides; Hydroxyl Radical; Iron; Monoamine Oxidase; Nerve Degeneration; Neural Pathways; Oxidation-Reduction; Parkinson Disease, Secondary; Potassium; Potassium Channels; Rats; Substantia Nigra | 1993 |
Generation of reactive oxygen species by tyrosine hydroxylase: a possible contribution to the degeneration of dopaminergic neurons?
Topics: Dopamine; Humans; Hydroxyl Radical; Nerve Degeneration; Neurons; Phosphorylation; Reactive Oxygen Species; Tyrosine 3-Monooxygenase | 1997 |
Apparent role of hydroxyl radicals in oxidative brain injury induced by sodium nitroprusside.
Topics: Animals; Ascorbic Acid; Brain Injuries; Deferoxamine; Hydrogen Peroxide; Hydroxyl Radical; In Vitro Techniques; Iron; Lipid Peroxidation; Male; Nerve Degeneration; Nitric Oxide; Nitroprusside; Oxidative Stress; Oxyhemoglobins; Penicillamine; Rats; Rats, Sprague-Dawley | 1998 |
Infant rat model of the shaken baby syndrome: preliminary characterization and evidence for the role of free radicals in cortical hemorrhaging and progressive neuronal degeneration.
Topics: Age Factors; Animals; Battered Child Syndrome; Brain Chemistry; Cerebral Hemorrhage; Disease Models, Animal; Free Radical Scavengers; Free Radicals; Head Injuries, Closed; Humans; Hydroxyl Radical; Hypoxia; Infant; Lipid Peroxidation; Male; Nerve Degeneration; Pregnatrienes; Rats; Rats, Sprague-Dawley; Vitamin E | 1998 |
Effects of cytisine on hydroxyl radicals in vitro and MPTP-induced dopamine depletion in vivo.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Alkaloids; Animals; Azocines; Benzenesulfonates; Dopamine; Dopamine Agents; Hydroxyl Radical; Male; Mice; Mice, Inbred C57BL; Motor Activity; Nerve Degeneration; Neurons; Neuroprotective Agents; Quinolizines | 1998 |
Allopurinol suppresses para-nonylphenol and 1-methyl-4-phenylpyridinium ion (MPP(+))-induced hydroxyl radical generation in rat striatum.
Topics: 1-Methyl-4-phenylpyridinium; Allopurinol; Animals; Dose-Response Relationship, Drug; Drug Interactions; Free Radical Scavengers; Hazardous Substances; Hydroxyl Radical; Male; Microdialysis; Neostriatum; Nerve Degeneration; Parkinson Disease; Parkinson Disease, Secondary; Phenols; Rats; Rats, Wistar | 2001 |
Release of dopamine by perfusion with 1-methyl-4-phenylpyridinium ion (MPP(+)) into the striatum is associated with hydroxyl free radical generation.
Topics: 1-Methyl-4-phenylpyridinium; Adrenergic Uptake Inhibitors; Animals; Antifungal Agents; Cell Membrane; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Space; Herbicides; Hydroxybenzoates; Hydroxyl Radical; Lipid Peroxidation; Male; Neostriatum; Nerve Degeneration; Neural Pathways; Neurons; Oxidative Stress; Rats; Rats, Wistar; Reserpine; Salicylic Acid; Substantia Nigra | 2001 |
3,4-Dihydroxyphenylacetaldehyde and hydrogen peroxide generate a hydroxyl radical: possible role in Parkinson's disease pathogenesis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Aldehydes; Brain; Catechols; Humans; Hydrogen Peroxide; Hydroxyl Radical; Male; Nerve Degeneration; Parkinson Disease; Spectrophotometry, Atomic | 2001 |
Endogenous released ascorbic acid suppresses ethanol-induced hydroxyl radical production in rat striatum.
Topics: Alcohol-Induced Disorders, Nervous System; Animals; Ascorbic Acid; Drug Interactions; Ethanol; Extracellular Space; Female; Fenfluramine; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Neostriatum; Nerve Degeneration; Neurons; Oxidative Stress; Rats; Selective Serotonin Reuptake Inhibitors; Sex Characteristics | 2002 |
On the possible role of iron-induced free radical peroxidation in neural degeneration in Alzheimer's disease.
Topics: Alzheimer Disease; Brain; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; Iron; Nerve Degeneration | 1992 |