hydroxyl radical has been researched along with MPTP Neurotoxicity Syndrome in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (25.00) | 18.2507 |
| 2000's | 9 (56.25) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pu, XP; Wang, YH; Zhai, SY; Zhang, HN; Zhou, JJ | 1 |
| Nakashima, M; Obata, T | 1 |
| Gowda, B; Jaisankar, P; Mohanakumar, KP; Nagashayana, N; Sengupta, T; Vinayagam, J | 1 |
| Obata, T | 2 |
| Bergh, JJ; Loots, DT; Mienie, LJ; Van der Schyf, CJ | 1 |
| Galoyan, AA; Knaryan, VH; Mohanakumar, KP; Samantaray, S | 1 |
| Galoyan, AA; Knaryan, VH; Mohanakumar, KP; Samantaray, S; Srinivasan, A; Varghese, M | 1 |
| Bennett, JP; Parker, WD; Smith, TS; Swerdlow, RH | 1 |
| Chiueh, CC; Krishna, G; Mohanakumar, KP; Murphy, DL; Obata, T; Sternberger, LM; Wu, RM | 1 |
| Chiueh, CC; Rauhala, P | 1 |
| Aubin, N; Carter, C; Curet, O; Deffois, A | 1 |
| Earl, CD; Ferger, B; Kuschinsky, K; Oertel, WH; Teismann, P | 1 |
| Mohanakumar, KP; Muralikrishnan, D; Thomas, B | 1 |
| Obata, T; Yamanaka, Y | 1 |
| Gu, J; Li, XJ; Lu, SD; Sun, FY | 1 |
4 review(s) available for hydroxyl radical and MPTP Neurotoxicity Syndrome
| Article | Year |
|---|---|
Dopamine efflux by MPTP and hydroxyl radical generation.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Angiotensin-Converting Enzyme Inhibitors; Animals; Dopamine; Humans; Hydroxyl Radical; MPTP Poisoning; Neostriatum; Nitric Oxide; Oxidative Stress; Presynaptic Terminals | 2002 |
In vivo generation of hydroxyl radicals and MPTP-induced dopaminergic toxicity in the basal ganglia.
Topics: Animals; Antioxidants; Basal Ganglia; Corpus Striatum; Dopamine; Free Radical Scavengers; Free Radicals; Humans; Hydroxyl Radical; Melanins; MPTP Poisoning; Nerve Degeneration; Parkinson Disease; Rats; Salicylates; Selegiline; Substantia Nigra | 1994 |
[Parkinsonism induced by MPTP and free radical generation].
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Antiparkinson Agents; Dopamine; Humans; Hydroxyl Radical; Iron; Monoamine Oxidase; MPTP Poisoning; Oxidative Stress | 2001 |
Role of hydroxyl radical formation in neurotoxicity as revealed by in vivo free radical trapping.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Brain; Cells, Cultured; Dopamine; Female; Herbicides; Humans; Hydroxyl Radical; Iron; Male; MPTP Poisoning; Parkinsonian Disorders | 2002 |
12 other study(ies) available for hydroxyl radical and MPTP Neurotoxicity Syndrome
| Article | Year |
|---|---|
Neuroprotective effects of 3-O-demethylswertipunicoside against MPTP-induced Parkinson's disease in vivo and its antioxidant properties in vitro.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Biphenyl Compounds; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Glucosides; Hippocampus; Hydroxyl Radical; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Motor Activity; MPTP Poisoning; Neuroprotective Agents; Picrates; Spine; Superoxides; Tyrosine 3-Monooxygenase; Xanthones | 2015 |
Opening of ATP-sensitive K(+) (KATP) channels enhance hydroxyl radical generation induced by MPP(+) in rat striatum.
Topics: Animals; Corpus Striatum; Cromakalim; Dopamine; Dose-Response Relationship, Drug; Glyburide; Hydroxybenzoates; Hydroxyl Radical; KATP Channels; Male; Membrane Transport Modulators; Microdialysis; MPTP Poisoning; Nicorandil; Rats, Wistar | 2016 |
Antiparkinsonian effects of aqueous methanolic extract of Hyoscyamus niger seeds result from its monoamine oxidase inhibitory and hydroxyl radical scavenging potency.
Topics: Animals; Antiparkinson Agents; Behavior, Animal; Disease Models, Animal; Free Radical Scavengers; Humans; Hydroxyl Radical; Hyoscyamus; Male; Medicine, Ayurvedic; Methanol; Mice; Mice, Inbred BALB C; Monoamine Oxidase; Monoamine Oxidase Inhibitors; MPTP Poisoning; Parkinson Disease; Plant Extracts | 2011 |
Acetyl-L-carnitine prevents total body hydroxyl free radical and uric acid production induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the rat.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Acetylcarnitine; Animals; Biomarkers; Gas Chromatography-Mass Spectrometry; Hydroxyl Radical; Male; MPTP Poisoning; Oxidative Stress; Protective Agents; Rats; Rats, Sprague-Dawley; Uric Acid | 2004 |
A synthetic human proline-rich-polypeptide enhances hydroxyl radical generation and fails to protect dopaminergic neurons against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced toxicity in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Chromatography, High Pressure Liquid; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Electrochemistry; Humans; Hydroxyl Radical; Mice; Mice, Inbred BALB C; MPTP Poisoning; Neurons; Peptides; Proline; Proline-Rich Protein Domains; Time Factors; Treatment Failure | 2005 |
Synthetic bovine proline-rich-polypeptides generate hydroxyl radicals and fail to protect dopaminergic neurons against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurotoxicity in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Biogenic Amines; Cattle; Cell-Free System; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agents; Hydroxyl Radical; Mice; Mice, Inbred BALB C; Mitochondria; MPTP Poisoning; Neurons; Neurotoxins; Parkinson Disease; Peptides; Proline-Rich Protein Domains | 2006 |
Reduction of MPP(+)-induced hydroxyl radical formation and nigrostriatal MPTP toxicity by inhibiting nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Corpus Striatum; Hydroxyl Radical; Male; Mitochondria; MPTP Poisoning; NAD(P)H Dehydrogenase (Quinone); Nitric Oxide Synthase; Prosencephalon; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Substantia Nigra | 1994 |
Free radicals and MPTP-induced selective destruction of substantia nigra compacta neurons.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Antioxidants; Dopamine; Free Radicals; Hydroxyl Radical; Melanins; MPTP Poisoning; Neurons; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species; Substantia Nigra | 1998 |
Aspirin and salicylate protect against MPTP-induced dopamine depletion in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Aspirin; Body Temperature; Corpus Striatum; Cyclooxygenase Inhibitors; Dexamethasone; Dopamine; Hydroxybenzoates; Hydroxyl Radical; Lysine; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase; MPTP Poisoning; Salicylates; Salicylic Acid; Serotonin; Synaptosomes | 1998 |
The protective effects of PBN against MPTP toxicity are independent of hydroxyl radical trapping.
Topics: Animals; Body Weight; Cyclic N-Oxides; Dopamine; Free Radical Scavengers; Hydroxyl Radical; Male; Mice; Mice, Inbred C57BL; Motor Activity; MPTP Poisoning; Nitrogen Oxides | 2000 |
Neuroprotection by sodium salicylate against 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-induced neurotoxicity.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Catalepsy; Cyclooxygenase Inhibitors; Dopamine; Dopamine Agents; Dyskinesia, Drug-Induced; Female; Free Radical Scavengers; Gentisates; Glutathione; Homovanillic Acid; Hydroxybenzoates; Hydroxyl Radical; Male; Mice; Mice, Inbred BALB C; Monoamine Oxidase; MPTP Poisoning; Neostriatum; Neuroprotective Agents; Sodium Salicylate; Substantia Nigra | 2000 |
Melatonin attenuates MPTP-induced dopaminergic neuronal injury associated with scavenging hydroxyl radical.
Topics: Animals; Brain; Dopamine; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Male; Melatonin; Mice; Mice, Inbred C57BL; MPTP Poisoning; Neurons; Tyrosine 3-Monooxygenase | 2002 |