hydroxyindoleacetic acid has been researched along with Vomiting in 44 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
Vomiting: The forcible expulsion of the contents of the STOMACH through the MOUTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the combined effect of granisetron and methylprednisolone against acute emesis induced by cytotoxic agents, we investigated the clinical response and the urinary excretion of 5-HIAA in 85 patients with ovarian cancer who received the same anticancer chemotherapeutic regimen in a prospective randomized trial." | 9.08 | Combination effect of granisetron and methylprednisolone for preventing emesis induced by cytotoxic agents. ( Cheng, X; Itamochi, H; Kigawa, J; Minagawa, Y; Okada, M; Terakawa, N, 1997) |
| "We compared the efficacy and safety of ondansetron (GR 38032F), a selective antagonist of serotonin S3 receptors, with that of placebo in controlling the nausea and vomiting induced by cisplatin treatment in 28 patients with cancer." | 9.06 | Efficacy of ondansetron (GR 38032F) and the role of serotonin in cisplatin-induced nausea and vomiting. ( Cubeddu, LX; Finn, AL; Fuenmayor, NT; Hoffmann, IS, 1990) |
| " Granisetron and its combination with dexamethasone for the treatment of delayed emesis following cisplatin (CDDP) administration were investigated using ferrets." | 7.70 | Effects of granisetron and its combination with dexamethasone on cisplatin-induced delayed emesis in the ferret. ( Endo, T; Fukunaka, N; Hirafuji, M; Kudo, R; Minami, M; Sagae, S, 1998) |
| "This study evaluated the relationship between prechemotherapy cortisol and 5-hydroxyindoleacetic acid (5-HIAA) excretion and chemotherapy-induced emesis." | 7.69 | 5-Hydroxyindoleacetic acid (5-HIAA) and cortisol excretion as predictors of chemotherapy-induced emesis. ( du Bois, A; Holy, R; Schaefer, W; Vach, W; Wechsel, U, 1996) |
| " Therefore, in this study we evaluated, in cancer patients, the temporal relationships between the increases in plasma CgA and urinary 5-hydroxyindoleacetic acid (5-HIAA) and the development of vomiting following dacarbazine, nitrogen mustard and cyclophosphamide treatments." | 7.69 | Plasma chromogranin A marks emesis and serotonin release associated with dacarbazine and nitrogen mustard but not with cyclophosphamide-based chemotherapies. ( Cubeddu, LX; Hoffmann, I; O'Connor, DT; Parmer, RJ, 1995) |
| "The aim of this study was to evaluate the efficacy and safety of ondansetron, an antagonist of 5-hydroxytryptamine type 3 (serotonin 3) (5-HT3) receptors, in controlling nausea and vomiting induced by antineoplastic therapy in children affected by cancer." | 7.68 | Ondansetron, an antagonist of 5-HT3 receptors, in the treatment of antineoplastic drug-induced nausea and vomiting in children. ( Calabria, C; Casale, F; Di Tullio, M; Indolfi, P; Lampa, E; Lucarelli, C; Matera, MG; Rossi, F, 1993) |
| "Ondansetron was extremely effective over this time in the control of emesis and nausea." | 6.68 | The pattern of emesis following high-dose cyclophosphamide and the anti-emetic efficacy of ondansetron. ( Beck, TM, 1995) |
| " The results may be summarized as follows: 1) The pharmacokinetic parameters of tropisetron revealed no significant change in the data between day 1 and day 5." | 6.68 | [Pharmacokinetic investigation of 5-day multiple dose of tropisetron capsule in patients who had received cisplatin and the usefulness of tropisetron capsule in the treatment of nausea and vomiting]. ( Akasaka, Y; Kimura, A; Nukariya, N; Ohtawa, M; Suminaga, M, 1995) |
| "Zatosetron treatment inhibited and delayed ipecac-induced emesis in both groups." | 6.67 | Effect of zatosetron on ipecac-induced emesis in dogs and healthy men. ( Cerimele, BJ; Gidda, JS; Goldberg, MJ; Schwartz, SM, 1994) |
| " A total of 40 crossbred barrows (initial weight 10 kg) were orally dosed with 0 or 200 mg of fusaric acid/kg of BW and five animals from each treatment were killed 4." | 5.28 | Effect of fusaric acid on brain regional neurochemistry and vomiting behavior in swine. ( MacDonald, EJ; Smith, TK, 1991) |
| " PCPA (2 g 8 hourly for 2 or 3 days prior to cisplatin) reduced the spontaneous urinary excretion of 5-hydroxyindoleacetic acid (5-HIAA), inhibited the increase in urinary 5-HIAA induced by cisplatin and markedly attenuated the acute period of nausea and vomiting associated with the cytotoxic drug." | 5.08 | Treatment with para-chlorophenylalanine antagonises the emetic response and the serotonin-releasing actions of cisplatin in cancer patients. ( Alfieri, AB; Cubeddu, LX, 1995) |
| "To evaluate the combined effect of granisetron and methylprednisolone against acute emesis induced by cytotoxic agents, we investigated the clinical response and the urinary excretion of 5-HIAA in 85 patients with ovarian cancer who received the same anticancer chemotherapeutic regimen in a prospective randomized trial." | 5.08 | Combination effect of granisetron and methylprednisolone for preventing emesis induced by cytotoxic agents. ( Cheng, X; Itamochi, H; Kigawa, J; Minagawa, Y; Okada, M; Terakawa, N, 1997) |
| "The aim of this study was to determine the mechanism of action of radiation-induced emesis by determining the incidence of radiation-induced emesis following hemibody irradiation; the effects of specific antiemetics especially ondansetron, a 5-hydroxytryptamine receptor antagonist, and to determine the relationship between radiation-induced emesis and serotonin (5-hydroxytryptamine) through its active metabolite, 5-hydroxyindoleacetic acid (5-HIAA)." | 5.07 | On the mechanism of radiation-induced emesis: the role of serotonin. ( Anderson, RF; Hoffman, LG; Ornitz, RD; Scarantino, CW, 1994) |
| "We compared the efficacy and safety of ondansetron (GR 38032F), a selective antagonist of serotonin S3 receptors, with that of placebo in controlling the nausea and vomiting induced by cisplatin treatment in 28 patients with cancer." | 5.06 | Efficacy of ondansetron (GR 38032F) and the role of serotonin in cisplatin-induced nausea and vomiting. ( Cubeddu, LX; Finn, AL; Fuenmayor, NT; Hoffmann, IS, 1990) |
| "One hundred eighteen patients with metastatic carcinoid tumor were randomized to treatment with streptozotocin combined with cyclophosphamide or with 5-fluorouracil (5-FU)." | 5.04 | Combination chemotherapy trials in metastatic carcinoid tumor and the malignant carcinoid syndrome. ( Hanley, JA; Moertel, CG, 1979) |
| " We theoretically evaluated the antiemetic effects of three 5-HT(3) receptor antagonists (granisetron, azasetron, palonosetron) on cisplatin-induced nausea and vomiting by estimating the time course of the 5-HT(3) receptor occupancy of serotonin." | 3.81 | Theoretical evaluation of antiemetic effects of 5-HT3 receptor antagonists for prevention of vomiting induced by cisplatin. ( Iwase, O; Nakajima, A; Nakamura, H; Okuyama, K; Takayanagi, R; Yamada, Y; Yokoyama, H; Yoshimoto, K, 2015) |
| "These preliminary findings suggest that an elevated pretreatment ratio of substance P to 5-HIAA/creatinine >70 is associated with the development of delayed vomiting induced by MEC." | 3.78 | Identification of a novel marker associated with risk for delayed chemotherapy-induced vomiting. ( Auber, ML; Higa, GM; Hobbs, G, 2012) |
| " In an attempt to clarify the mechanisms of emesis induced by cytotoxic drugs, we measured kaolin ingestion (pica) and the tissue concentrations of 5-HT, norepinephrine (NE) and dopamine in various brain regions of rats after cisplatin administration." | 3.72 | 5-hydroxytryptamine (5-HT) concentrations in the hippocampus, the hypothalamus and the medulla oblongata related to cisplatin-induced pica of rats. ( Endo, T; Hamaue, N; Hirafuji, M; Liu, Y; Minami, M, 2003) |
| "Highly emetogenic drugs such as cisplatin induce an increase in the urinary 5-hydroxyindoleacetic acid (5-HIAA) level, the main metabolite of serotonin (5-HT), within the first 24 h following a single infusion, thus providing a possible cause for acute emesis and an explanation for the action of 5-HT3 antagonists." | 3.70 | Urinary 5-hydroxyindoleacetic acid (5-HIAA) excretion during multiple-day high-dose chemotherapy. ( Janes, RJ; Karjalainen, UP; Muhonen, T; Wiklund, T, 1998) |
| " Granisetron and its combination with dexamethasone for the treatment of delayed emesis following cisplatin (CDDP) administration were investigated using ferrets." | 3.70 | Effects of granisetron and its combination with dexamethasone on cisplatin-induced delayed emesis in the ferret. ( Endo, T; Fukunaka, N; Hirafuji, M; Kudo, R; Minami, M; Sagae, S, 1998) |
| " Therefore, in this study we evaluated, in cancer patients, the temporal relationships between the increases in plasma CgA and urinary 5-hydroxyindoleacetic acid (5-HIAA) and the development of vomiting following dacarbazine, nitrogen mustard and cyclophosphamide treatments." | 3.69 | Plasma chromogranin A marks emesis and serotonin release associated with dacarbazine and nitrogen mustard but not with cyclophosphamide-based chemotherapies. ( Cubeddu, LX; Hoffmann, I; O'Connor, DT; Parmer, RJ, 1995) |
| " The urinary excretion of 5-hydroxyindoleacetic acid (5-HIAA), the main metabolite of serotonin, was measured in 13 women with pregnancy-induced emesis, 12 patients who had nausea and vomiting following inner-ear dysfunctions, 27 patients with cisplatin-induced emesis and a control group of 21 women." | 3.69 | The role of serotonin as a mediator of emesis induced by different stimuli. ( du Bois, A; Kriesinger-Schroeder, H; Meerpohl, HG, 1995) |
| "This study evaluated the relationship between prechemotherapy cortisol and 5-hydroxyindoleacetic acid (5-HIAA) excretion and chemotherapy-induced emesis." | 3.69 | 5-Hydroxyindoleacetic acid (5-HIAA) and cortisol excretion as predictors of chemotherapy-induced emesis. ( du Bois, A; Holy, R; Schaefer, W; Vach, W; Wechsel, U, 1996) |
| " The time course of the increase in plasma CgA matched that of emesis and of urinary 5-hydroxyindoleacetic acid (5-HIAA)." | 3.69 | Plasma chromogranin A: a marker of serotonin release and of emesis associated with cisplatin chemotherapy. ( Cubeddu, LX; O'Connor, DT; Parmer, RJ, 1995) |
| "The aim of this study was to evaluate the efficacy and safety of ondansetron, an antagonist of 5-hydroxytryptamine type 3 (serotonin 3) (5-HT3) receptors, in controlling nausea and vomiting induced by antineoplastic therapy in children affected by cancer." | 3.68 | Ondansetron, an antagonist of 5-HT3 receptors, in the treatment of antineoplastic drug-induced nausea and vomiting in children. ( Calabria, C; Casale, F; Di Tullio, M; Indolfi, P; Lampa, E; Lucarelli, C; Matera, MG; Rossi, F, 1993) |
| " Comparisons between SP data stratified by cisplatin dosage and emetic phase were significantly different, P < 0." | 2.72 | 5-Hydroxyindoleacetic acid and substance P profiles in patients receiving emetogenic chemotherapy. ( Altaha, R; Auber, ML; Higa, GM; Hobbs, G; Kurian, S; Landreth, K; Piktel, D, 2006) |
| "In patients with cancer (n = 16), baseline blood dialysate 5-HIAA concentrations averaged 2." | 2.69 | Use of intravenous microdialysis to monitor changes in serotonin release and metabolism induced by cisplatin in cancer patients: comparative effects of granisetron and ondansetron. ( Castejon, AM; Cubeddu, LX; Hernandez, L; Paez, X, 1999) |
| " The results may be summarized as follows: 1) The pharmacokinetic parameters of tropisetron revealed no significant change in the data between day 1 and day 5." | 2.68 | [Pharmacokinetic investigation of 5-day multiple dose of tropisetron capsule in patients who had received cisplatin and the usefulness of tropisetron capsule in the treatment of nausea and vomiting]. ( Akasaka, Y; Kimura, A; Nukariya, N; Ohtawa, M; Suminaga, M, 1995) |
| "Ondansetron was extremely effective over this time in the control of emesis and nausea." | 2.68 | The pattern of emesis following high-dose cyclophosphamide and the anti-emetic efficacy of ondansetron. ( Beck, TM, 1995) |
| "Zatosetron treatment inhibited and delayed ipecac-induced emesis in both groups." | 2.67 | Effect of zatosetron on ipecac-induced emesis in dogs and healthy men. ( Cerimele, BJ; Gidda, JS; Goldberg, MJ; Schwartz, SM, 1994) |
| "Primary carcinoid tumors of the liver are rare, with fewer than 60 cases currently reported in the English literature." | 1.35 | Primary hepatic carcinoid tumor in children. ( Debski, R; Foley, DS; Ignacio, RC; Nagaraj, HS; Sunil, I, 2008) |
| " This study was conducted to evaluate parameters of serotonin metabolism following platinum-based chemotherapy given in combination with the serotonin type-3 antagonist tropisetron as an antiemetic agent." | 1.29 | Serotonin metabolism following platinum-based chemotherapy combined with the serotonin type-3 antagonist tropisetron. ( de Vries, EG; Groenewegen, A; Kema, IP; Schröder, CP; Sleijfer, DT; van der Graaf, WT, 1995) |
| " A total of 40 crossbred barrows (initial weight 10 kg) were orally dosed with 0 or 200 mg of fusaric acid/kg of BW and five animals from each treatment were killed 4." | 1.28 | Effect of fusaric acid on brain regional neurochemistry and vomiting behavior in swine. ( MacDonald, EJ; Smith, TK, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (18.18) | 18.7374 |
| 1990's | 27 (61.36) | 18.2507 |
| 2000's | 7 (15.91) | 29.6817 |
| 2010's | 2 (4.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakamura, H | 1 |
| Yokoyama, H | 1 |
| Takayanagi, R | 1 |
| Yoshimoto, K | 1 |
| Nakajima, A | 1 |
| Okuyama, K | 1 |
| Iwase, O | 1 |
| Yamada, Y | 1 |
| Foley, DS | 1 |
| Sunil, I | 1 |
| Debski, R | 1 |
| Ignacio, RC | 1 |
| Nagaraj, HS | 1 |
| Higa, GM | 2 |
| Auber, ML | 2 |
| Hobbs, G | 2 |
| Liu, Y | 1 |
| Hamaue, N | 2 |
| Endo, T | 4 |
| Hirafuji, M | 3 |
| Minami, M | 4 |
| Altaha, R | 1 |
| Piktel, D | 1 |
| Kurian, S | 1 |
| Landreth, K | 1 |
| Bennett, MI | 1 |
| Livingstone, HJ | 1 |
| Costello, P | 1 |
| Allen, KR | 1 |
| Degg, TJ | 1 |
| Hartvig, P | 1 |
| Kemperman, RF | 1 |
| Muskiet, FD | 1 |
| Boutier, AI | 1 |
| Kema, IP | 2 |
| Muskiet, FA | 1 |
| Utkin, VM | 1 |
| Stroev, EA | 1 |
| Gusak, IU | 1 |
| Eniushin, VD | 1 |
| Murakawa, M | 1 |
| Adachi, T | 1 |
| Nakao, S | 1 |
| Seo, N | 1 |
| Shingu, K | 1 |
| Mori, K | 1 |
| Schwartz, SM | 1 |
| Goldberg, MJ | 1 |
| Gidda, JS | 1 |
| Cerimele, BJ | 1 |
| Scarantino, CW | 1 |
| Ornitz, RD | 1 |
| Hoffman, LG | 1 |
| Anderson, RF | 1 |
| Alfieri, AB | 1 |
| Cubeddu, LX | 7 |
| O'Connor, DT | 2 |
| Parmer, RJ | 2 |
| Beck, TM | 1 |
| Suminaga, M | 1 |
| Akasaka, Y | 1 |
| Nukariya, N | 1 |
| Kimura, A | 1 |
| Ohtawa, M | 1 |
| Hoffmann, I | 2 |
| Schröder, CP | 1 |
| van der Graaf, WT | 1 |
| Groenewegen, A | 1 |
| Sleijfer, DT | 1 |
| de Vries, EG | 1 |
| Wilder-Smith, OH | 1 |
| Borgeat, A | 1 |
| Chappuis, P | 1 |
| Fathi, M | 1 |
| Forni, M | 1 |
| Hoffmann, IS | 3 |
| Matera, MG | 1 |
| Di Tullio, M | 1 |
| Lucarelli, C | 1 |
| Casale, F | 1 |
| Calabria, C | 1 |
| Lampa, E | 1 |
| Indolfi, P | 1 |
| Rossi, F | 1 |
| du Bois, A | 4 |
| Kriesinger-Schroeder, H | 2 |
| Meerpohl, HG | 1 |
| Vach, W | 3 |
| Wechsel, U | 2 |
| Holy, R | 3 |
| Schaefer, W | 1 |
| Kriesinger-Schröder, H | 1 |
| Kigawa, J | 1 |
| Minagawa, Y | 1 |
| Itamochi, H | 1 |
| Cheng, X | 1 |
| Okada, M | 1 |
| Terakawa, N | 1 |
| Siebert, C | 1 |
| Ledergerber, M | 1 |
| Janes, RJ | 1 |
| Muhonen, T | 1 |
| Karjalainen, UP | 1 |
| Wiklund, T | 1 |
| Fukunaka, N | 1 |
| Sagae, S | 1 |
| Kudo, R | 1 |
| Rudd, JA | 1 |
| Cheng, CH | 1 |
| Naylor, RJ | 1 |
| Castejon, AM | 1 |
| Paez, X | 1 |
| Hernandez, L | 1 |
| Nemoto, M | 1 |
| Ogawa, T | 1 |
| Tamakai, H | 1 |
| Takeda, Y | 1 |
| Hasegawa, M | 1 |
| Fugii, Y | 1 |
| Moertel, CG | 1 |
| Hanley, JA | 1 |
| Cubeddu, L | 1 |
| Fuenmayor, N | 1 |
| Fuenmayor, NT | 2 |
| Malave, JJ | 1 |
| Finn, AL | 1 |
| Monma, Y | 1 |
| Saito, H | 2 |
| Takeuchi, M | 1 |
| Smith, TK | 1 |
| MacDonald, EJ | 1 |
| Torii, Y | 1 |
| Matsuki, N | 1 |
| Lucot, JB | 1 |
| Crampton, GH | 1 |
| Matson, WR | 1 |
| Gamache, PH | 1 |
| Rinne, UK | 1 |
| Sonninen, V | 1 |
| Sirtola, T | 1 |
| Mori, I | 1 |
| Maki, Y | 1 |
| Isyuin, Y | 1 |
| Tsukuda, A | 1 |
| Takeda, M | 1 |
| Martin, WR | 1 |
| Sloan, JW | 1 |
| Tandon, RN | 1 |
| Sur, BK | 1 |
| Nath, K | 1 |
| Tamarkin, NR | 1 |
| Goodwin, FK | 1 |
| Axelrod, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Ondansetron Premedication Trial in Juvenile Idiopathic Arthritis[NCT04169828] | 176 participants (Anticipated) | Interventional | 2019-08-02 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for hydroxyindoleacetic acid and Vomiting
| Article | Year |
|---|---|
[Psychosomatic medicine in pregnant and puerperal women].
Topics: Abortion, Threatened; Autonomic Nervous System; Epinephrine; Female; Humans; Hydroxyindoleacetic Aci | 1969 |
13 trials available for hydroxyindoleacetic acid and Vomiting
| Article | Year |
|---|---|
5-Hydroxyindoleacetic acid and substance P profiles in patients receiving emetogenic chemotherapy.
Topics: Adult; Aged; Analysis of Variance; Antiemetics; Antineoplastic Agents; Biomarkers; Chromatography, H | 2006 |
Effect of zatosetron on ipecac-induced emesis in dogs and healthy men.
Topics: Administration, Oral; Adult; Animals; Benzofurans; Bridged Bicyclo Compounds; Bridged Bicyclo Compou | 1994 |
On the mechanism of radiation-induced emesis: the role of serotonin.
Topics: Dexamethasone; Drug Therapy, Combination; Female; Hemibody Irradiation; Humans; Hydroxyindoleacetic | 1994 |
Treatment with para-chlorophenylalanine antagonises the emetic response and the serotonin-releasing actions of cisplatin in cancer patients.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fenclonine; Gastrointestin | 1995 |
The pattern of emesis following high-dose cyclophosphamide and the anti-emetic efficacy of ondansetron.
Topics: Antiemetics; Cyclophosphamide; Double-Blind Method; Female; Humans; Hydroxyindoleacetic Acid; Male; | 1995 |
[Pharmacokinetic investigation of 5-day multiple dose of tropisetron capsule in patients who had received cisplatin and the usefulness of tropisetron capsule in the treatment of nausea and vomiting].
Topics: Adult; Aged; Antiemetics; Capsules; Cisplatin; Drug Administration Schedule; Humans; Hydroxyindoleac | 1995 |
5-Hydroxyindoleacetic acid excretion following combination chemotherapy with cyclophosphamide, epirubicin and 5-fluorouracil plus ondansetron compared to ondansetron alone.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antiemetics; Antimetabolites, Antineoplastic; Antineoplast | 1996 |
Combination effect of granisetron and methylprednisolone for preventing emesis induced by cytotoxic agents.
Topics: Adult; Aged; Antineoplastic Agents; Drug Therapy, Combination; Female; Granisetron; Humans; Hydroxyi | 1997 |
Use of intravenous microdialysis to monitor changes in serotonin release and metabolism induced by cisplatin in cancer patients: comparative effects of granisetron and ondansetron.
Topics: Adult; Aged; Antineoplastic Agents; Cisplatin; Female; Granisetron; Humans; Hydroxyindoleacetic Acid | 1999 |
Combination chemotherapy trials in metastatic carcinoid tumor and the malignant carcinoid syndrome.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Carcinoid Tumor; Child; Clinical Trials as Topic; Cy | 1979 |
Efficacy of ondansetron (GR 38032F) and the role of serotonin in cisplatin-induced nausea and vomiting.
Topics: Adult; Aged; Antiemetics; Cisplatin; Double-Blind Method; Female; Humans; Hydroxyindoleacetic Acid; | 1990 |
Treatment of Parkinson's disease with L-DOPA and decarboxylase inhibitor.
Topics: Biopsy; Carboxy-Lyases; Clinical Trials as Topic; Dihydroxyphenylalanine; Drug Combinations; Drug Sy | 1972 |
Effects of infused tryptamine in man.
Topics: Blood Pressure; Clinical Trials as Topic; Creatinine; Dopamine; Epinephrine; Hearing; Humans; Hydrog | 1970 |
30 other studies available for hydroxyindoleacetic acid and Vomiting
| Article | Year |
|---|---|
Theoretical evaluation of antiemetic effects of 5-HT3 receptor antagonists for prevention of vomiting induced by cisplatin.
Topics: Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Cisplatin; Constipation; Creatinine; | 2015 |
Primary hepatic carcinoid tumor in children.
Topics: Adolescent; Back Pain; Biomarkers, Tumor; Carcinoid Tumor; Chromogranin A; Follow-Up Studies; Hematu | 2008 |
Identification of a novel marker associated with risk for delayed chemotherapy-induced vomiting.
Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Biomarkers; Case-Control Studies; Creatinine; Dexam | 2012 |
5-hydroxytryptamine (5-HT) concentrations in the hippocampus, the hypothalamus and the medulla oblongata related to cisplatin-induced pica of rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antineoplastic Agents; Brain; Cisplatin; Dopamine; Hydroxyi | 2003 |
Symptom scores, serotonin and 5-hydroxyindole acetic acid levels in cancer patients with and without bowel obstruction.
Topics: Aged; Female; Humans; Hydroxyindoleacetic Acid; Intestinal Obstruction; Middle Aged; Ovarian Neoplas | 2007 |
Re: 5-Hydroxyindoleacetic acid and substance P profiles in patients receiving emetogenic chemotherapy.
Topics: Antiemetics; Antineoplastic Agents; Humans; Hydroxyindoleacetic Acid; Nausea; Serotonin 5-HT3 Recept | 2007 |
Brief report: normal intestinal permeability at elevated platelet serotonin levels in a subgroup of children with pervasive developmental disorders in Curaçao (The Netherlands antilles).
Topics: Blood Platelets; Child; Child Development Disorders, Pervasive; Diarrhea; Female; Humans; Hydroxyind | 2008 |
[Serotonin-5-hydroxyindoleacetic acid system and estrogen excretion in emesis gravidarum].
Topics: Adolescent; Adult; Drug Therapy, Combination; Estrogens; Female; Humans; Hydroxyindoleacetic Acid; P | 1982 |
Activation of the cortical and medullary dopaminergic systems by nitrous oxide in rats: a possible neurochemical basis for psychotropic effects and postanesthetic nausea and vomiting.
Topics: Anesthesia; Animals; Biogenic Amines; Brain; Dihydroxyphenylalanine; Dopamine; Homovanillic Acid; Hy | 1994 |
Plasma chromogranin A: a marker of serotonin release and of emesis associated with cisplatin chemotherapy.
Topics: Adolescent; Adult; Analysis of Variance; Chromogranin A; Chromogranins; Cisplatin; Enterochromaffin | 1995 |
Plasma chromogranin A marks emesis and serotonin release associated with dacarbazine and nitrogen mustard but not with cyclophosphamide-based chemotherapies.
Topics: Adult; Antineoplastic Agents; Chromogranin A; Chromogranins; Cyclophosphamide; Dacarbazine; Female; | 1995 |
Serotonin metabolism following platinum-based chemotherapy combined with the serotonin type-3 antagonist tropisetron.
Topics: Adult; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorpromazine; Cispl | 1995 |
Urinary serotonin metabolite excretion during cisplatin chemotherapy.
Topics: Adult; Aged; Cisplatin; Female; Humans; Hydroxyindoleacetic Acid; Middle Aged; Nausea; Serotonin; Ti | 1993 |
Participation of serotonin on early and delayed emesis induced by initial and subsequent cycles of cisplatinum-based chemotherapy: effects of antiemetics.
Topics: Adult; Cisplatin; Dexamethasone; Dose-Response Relationship, Drug; Female; Humans; Hydroxyindoleacet | 1993 |
Ondansetron, an antagonist of 5-HT3 receptors, in the treatment of antineoplastic drug-induced nausea and vomiting in children.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Humans; Hydroxyindoleacetic | 1993 |
The role of serotonin as a mediator of emesis induced by different stimuli.
Topics: Cisplatin; Female; Humans; Hydroxyindoleacetic Acid; Pregnancy; Pregnancy Complications; Serotonin; | 1995 |
5-Hydroxyindoleacetic acid (5-HIAA) and cortisol excretion as predictors of chemotherapy-induced emesis.
Topics: Adult; Aged; Antineoplastic Agents; Biomarkers; Female; Humans; Hydrocortisone; Hydroxyindoleacetic | 1996 |
The relationship between parameters of serotonin metabolism and emetogenic potential of platinum-based chemotherapy regimens.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisp | 1997 |
Urinary 5-hydroxyindoleacetic acid (5-HIAA) excretion during multiple-day high-dose chemotherapy.
Topics: Adult; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans | 1998 |
Effects of granisetron and its combination with dexamethasone on cisplatin-induced delayed emesis in the ferret.
Topics: Animals; Antiemetics; Antineoplastic Agents; Blood Urea Nitrogen; Cisplatin; Creatine; Defecation; D | 1998 |
Serotonin-independent model of cisplatin-induced emesis in the ferret.
Topics: 5-Hydroxytryptophan; Animals; Brain; Cisplatin; Cross-Linking Reagents; Dopamine; Epinephrine; Fencl | 1998 |
Pharmacological aspects of ipecac syrup (TJN-119)-induced emesis in ferrets.
Topics: Afferent Pathways; Animals; Emetics; Emetine; Ferrets; Hydroxyindoleacetic Acid; Ileum; Ipecac; Medu | 2000 |
Serotonin and emesis--from animals to humans: a discussion of Professor Naylor's paper.
Topics: Animals; Cisplatin; Cyclophosphamide; Dogs; Ferrets; Humans; Hydroxyindoleacetic Acid; Neoplasms; Se | 1992 |
Changes in serotonin metabolism in cancer patients: its relationship to nausea and vomiting induced by chemotherapeutic drugs.
Topics: Adult; Analysis of Variance; Antineoplastic Agents; Blood Platelets; Cisplatin; Cyclophosphamide; Do | 1992 |
Emesis-related biochemical and histopathological changes induced by cisplatin in the ferret.
Topics: Animals; Cisplatin; Dopamine; Ferrets; Hydroxyindoleacetic Acid; Intestinal Mucosa; Male; Norepineph | 1990 |
Effect of fusaric acid on brain regional neurochemistry and vomiting behavior in swine.
Topics: Administration, Oral; Animals; Behavior, Animal; Brain Chemistry; Catecholamines; Fusaric Acid; Hydr | 1991 |
5-Hydroxytryptamine is emetogenic in the house musk shrew, Suncus murinus.
Topics: 5-Methoxytryptamine; Animals; Female; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Injecti | 1991 |
Cerebrospinal fluid constituents of cat vary with susceptibility to motion sickness.
Topics: Animals; Cats; Disease Susceptibility; Dopamine; Female; Homovanillic Acid; Hydroxyindoleacetic Acid | 1989 |
Effect of reserpine injections in migrainous and normal control subjects, with estimations of urinary 5-hydroxyindoleacetic acid.
Topics: Adult; Headache; Humans; Hydroxyindoleacetic Acid; Injections, Subcutaneous; Male; Migraine Disorder | 1969 |
Rapid elevation of biogenic amine metabolites in human CSF following probenecid.
Topics: Administration, Oral; Affective Symptoms; Dihydroxyphenylalanine; Female; Headache; Humans; Hydroxyi | 1970 |