hydroxyindoleacetic acid has been researched along with Uremia in 12 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tyrosine (Tyr), tyrosine hydroxylase (TH), tryptophan (Trp), serotonin (5-HT), and 5-hydroxyindole acetic acid (5-HIAA) were assayed spectrofluorometrically and radioenzymatically in various regions of post-mortem brains of human patients with hepatic, uremic, and diabetic coma, liver cirrhosis without coma, and hepatic coma treated with parenteral administration of L-valine, a branched-chain amino acid." | 3.66 | Brain monoamines in hepatic encephalopathy and other types of metabolic coma. ( Jellinger, K; Kothbauer, P; Rausch, WD; Riederer, P, 1978) |
| "The subjects with encephalopathy had raised plasma free tryptophan, CSF tryptophan, and CSF 5-hydroxyindoleacetic acid." | 1.26 | Cerebral transmitter precursors and metabolites in advanced renal disease. ( Callaghan, N; Curzon, G; Kantamaneni, BD; Murnaghan, D; Sullivan, PA, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (75.00) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ohtsuki, S | 1 |
| Asaba, H | 1 |
| Takanaga, H | 1 |
| Deguchi, T | 1 |
| Hosoya, K | 1 |
| Otagiri, M | 1 |
| Terasaki, T | 1 |
| Sullivan, PA | 2 |
| Murnaghan, D | 2 |
| Callaghan, N | 2 |
| Kantamaneni, BD | 2 |
| Curzon, G | 2 |
| Qureshi, AR | 1 |
| Lindholm, B | 1 |
| Garcia, E | 1 |
| Groth, CG | 1 |
| Bergström, J | 1 |
| Qureshi, GA | 1 |
| Baig, SM | 1 |
| Jellinger, K | 3 |
| Riederer, P | 3 |
| Rausch, WD | 1 |
| Kothbauer, P | 2 |
| Swendseid, ME | 2 |
| Wang, M | 2 |
| Vyhmeister, I | 1 |
| Chan, W | 1 |
| Siassi, F | 2 |
| Tam, CF | 1 |
| Kopple, JD | 2 |
| Ksiazek, A | 1 |
| Kleinberger, G | 1 |
| Wuketich, S | 1 |
| Essman, WB | 1 |
| Heldman, E | 1 |
12 other studies available for hydroxyindoleacetic acid and Uremia
| Article | Year |
|---|---|
Role of blood-brain barrier organic anion transporter 3 (OAT3) in the efflux of indoxyl sulfate, a uremic toxin: its involvement in neurotransmitter metabolite clearance from the brain.
Topics: Animals; Antimetabolites; Biological Transport; Blood-Brain Barrier; Brain; Capillaries; Cells, Cult | 2002 |
Effect of dialysis on plasma and CSF tryptophan and CSF 5-hydroxyindoleacetic acid in advanced renal disease.
Topics: Adult; Fatty Acids, Nonesterified; Heparin; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Neu | 1980 |
Tryptophan and its metabolites in patients on continuous ambulatory peritoneal dialysis and following renal transplantation.
Topics: Adult; Aged; Amino Acids; Case-Control Studies; Female; Humans; Hydroxyindoleacetic Acid; Kidney Tra | 1994 |
The role of tryptophan, 5-hydroxy indole-3-acetic acid and their protein binding in uremic patients.
Topics: Adult; Aged; Catecholamines; Chromatography, High Pressure Liquid; Female; Humans; Hydroxyindoleacet | 1993 |
Cerebral transmitter precursors and metabolites in advanced renal disease.
Topics: Adult; Aged; Brain; Brain Diseases; Fatty Acids, Nonesterified; Female; Homovanillic Acid; Humans; H | 1978 |
Brain monoamines in hepatic encephalopathy and other types of metabolic coma.
Topics: Aged; Animals; Brain; Coma; Diabetic Coma; Female; Hepatic Encephalopathy; Humans; Hydroxyindoleacet | 1978 |
Amino acid metabolism in the chronically uremic rat.
Topics: Amine Oxidase (Copper-Containing); Amines; Amino Acids; Animals; Argininosuccinate Lyase; Argininosu | 1975 |
Plasma tryptophan levels and brain serotonin metabolism in chronically uremic rats.
Topics: Animals; Brain; Caseins; Chronic Disease; Dietary Proteins; DNA; Female; Humans; Hydroxyindoleacetic | 1977 |
[Serotonin and 5-hydroxyindoloacetic acid in rats with experimental uremia (author's transl)].
Topics: Animals; Brain Chemistry; Female; Hydroxyindoleacetic Acid; Kidney; Liver; Male; Rats; Serotonin; Sp | 1977 |
Brain monoamines in human hepatic encephalopathy.
Topics: Aged; Brain Chemistry; Brain Stem; Coma; Diabetic Coma; Dopamine; Hepatic Encephalopathy; Humans; Hy | 1978 |
Brain monoamines in metabolic (endotoxic) coma. A preliminary biochemical study in human postmortem material.
Topics: Aged; Brain Chemistry; Coma; Dopamine; Female; Hepatic Encephalopathy; Humans; Hydroxyindoleacetic A | 1977 |
Impairment of avoidance acquisition and altered regional brain amine levels in mice with uremic endotoxemia.
Topics: Animals; Avoidance Learning; Blood Urea Nitrogen; Brain; Brain Chemistry; Cerebellum; Diencephalon; | 1972 |