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hydroxyindoleacetic acid and Tremor

hydroxyindoleacetic acid has been researched along with Tremor in 32 studies

(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.

Tremor: Cyclical movement of a body part that can represent either a physiologic process or a manifestation of disease. Intention or action tremor, a common manifestation of CEREBELLAR DISEASES, is aggravated by movement. In contrast, resting tremor is maximal when there is no attempt at voluntary movement, and occurs as a relatively frequent manifestation of PARKINSON DISEASE.

Research Excerpts

ExcerptRelevanceReference
"The aim of the present study was to examine the influence of a unilateral 6-hydroxydopamine (6-OHDA)-induced partial lesion of both the substantia nigra pars compacta (SNc, A9) and retrorubral field (RRF, A8) on the tremor evoked by harmaline."7.786-OHDA injections into A8-A9 dopaminergic neurons modelling early stages of Parkinson's disease increase the harmaline-induced tremor in rats. ( Berghauzen, K; Kolasiewicz, W; Kuter, K; Nowak, P; Ossowska, K; Schulze, G, 2012)
"The purpose of this study was to correlate the chlordecone-elicited tremor activity with alterations of brain neurotransmitters."7.67Effects of chlordecone exposure on brain neurotransmitters: possible involvement of the serotonin system in chlordecone-elicited tremor. ( Gerhart, J; Hong, JS; Tilson, HA; Uphouse, LL; Wilson, WE, 1984)
"The relationships between behavioral responses and levels of serotonin (5-HT) and 5-hydroxyindoleacetic acid (5-HIAA) in brain of mice were investigated after intravenous injection of fumitremorgin A (FTA)."7.66Biochemical investigation on the abnormal behaviors induced by fumitremorgin A, a tremorgenic mycotoxin to mice. ( Ozaki, N; Suzuki, S; Yamazaki, M, 1983)
"Alterations of steady state and metabolism of putative neurotransmitters were studied in the brain of rats with a sustained tremor evoked by nicotine and pilocarpine."7.66Possible mechanisms of sustained tremor induction by nicotine in pilocarpine treated animals. ( Dohi, T; Tsujimoto, A, 1978)
"Tremor is the second most common neurological adverse effect in patients receiving treatment with SSRIs."5.32Citalopram, a selective serotonin reuptake inhibitor augments harmaline-induced tremor in rats. ( Al Deeb, S; Al Kadasah, S; Al Moutaery, K; Arshaduddin, M; Biary, N; Tariq, M, 2004)
"The aim of the present study was to examine the influence of a unilateral 6-hydroxydopamine (6-OHDA)-induced partial lesion of both the substantia nigra pars compacta (SNc, A9) and retrorubral field (RRF, A8) on the tremor evoked by harmaline."3.786-OHDA injections into A8-A9 dopaminergic neurons modelling early stages of Parkinson's disease increase the harmaline-induced tremor in rats. ( Berghauzen, K; Kolasiewicz, W; Kuter, K; Nowak, P; Ossowska, K; Schulze, G, 2012)
"The administration of veratramine produced generalized tremor, myoclonus, hindlimb abduction, backward gait and Straub tail, similar to the "5-hydroxytryptamine (5-HT) syndrome", in mice."3.68Veratramine-induced behavior associated with serotonergic hyperfunction in mice. ( Izumi, K; Nagata, R, 1991)
"The purpose of this study was to correlate the chlordecone-elicited tremor activity with alterations of brain neurotransmitters."3.67Effects of chlordecone exposure on brain neurotransmitters: possible involvement of the serotonin system in chlordecone-elicited tremor. ( Gerhart, J; Hong, JS; Tilson, HA; Uphouse, LL; Wilson, WE, 1984)
"The relationships between behavioral responses and levels of serotonin (5-HT) and 5-hydroxyindoleacetic acid (5-HIAA) in brain of mice were investigated after intravenous injection of fumitremorgin A (FTA)."3.66Biochemical investigation on the abnormal behaviors induced by fumitremorgin A, a tremorgenic mycotoxin to mice. ( Ozaki, N; Suzuki, S; Yamazaki, M, 1983)
"Alterations of steady state and metabolism of putative neurotransmitters were studied in the brain of rats with a sustained tremor evoked by nicotine and pilocarpine."3.66Possible mechanisms of sustained tremor induction by nicotine in pilocarpine treated animals. ( Dohi, T; Tsujimoto, A, 1978)
"Amantadine-induced tremor has been investigated using mice."3.65Amantadin e tremor, a 5-hydroxytryptamine-mediated response? ( Cox, B; Tha, SJ, 1975)
"Oxotremorine did not alter the level of 5-HT and 5-hydroxyindoleacetic acid in different brain regions."3.65Serotonin content in the central nervous system of rats and cholinergic tremor. ( Funk, KF; Oelszner, W; Staib, AH; Westermann, KH, 1975)
"A single dose of p-chloroamphetamine, 10 mg per kilogram, produced postural abnormalities, tremor, myoclonus, and autonomic signs in rats 5 minutes after intraperitoneal injection."3.65Postural changes, tremor, and myoclonus in the rat immediately following injections of p-chloromaphetamine. ( Growdon, JH, 1977)
"We have studied the urinary excretion of 1,4-methylhistamine (1,4-MeHm), 5-hydroxyindole-3-acetic acid (5-HIAA) and homovanillic acid (HVA) in patients with Parkinson's disease, choreiform movements and essential tremor."3.65Urinary monoamine metabolite excretion in disorders of movement. Effects of amantadine and levodopa. ( Fleming, AM; Lenman, JA; Reid, A; Turnbull, MJ, 1977)
" High doses of clorgyline, a selective inhibitor MAO-A, produced a characteristic stereotyped syndrome of hypermotility and tremor as well as an increase in apparent 5-HT and a decrease in apparent 5-HIAA in brain."3.65The inhibition of A and B forms of MAO in the production of a characteristic behabioural syndrome in rats after 1-tryptophan loading. ( Lassen, JB; Squires, RF, 1975)
" The effect of chronic ACTH treatment on 5-HT(2) receptor and 5-HT(2A)-receptor mRNA levels was not altered by the chronic administration of imipramine."1.35Increased DOI-induced wet-dog shakes in adrenocorticotropic hormone-treated rats are not affected by chronic imipramine treatment: possible involvement of enhanced 5-HT(2A)-receptor expression in the frontal cortex. ( Akiyama, K; Fujitani, Y; Gomita, Y; Kanzaki, H; Kawasaki, H; Kimoto, S; Kitagawa, K; Kitamura, Y; Ouchida, M; Sendo, T; Shibata, K; Shimizu, K, 2008)
"Tremor is the second most common neurological adverse effect in patients receiving treatment with SSRIs."1.32Citalopram, a selective serotonin reuptake inhibitor augments harmaline-induced tremor in rats. ( Al Deeb, S; Al Kadasah, S; Al Moutaery, K; Arshaduddin, M; Biary, N; Tariq, M, 2004)
"Pretreatment with phenytoin significantly attenuated the tremor produced by p,p'-DDT but enhanced that produced by chlordecone."1.275,5-Diphenylhydantoin antagonizes neurochemical and behavioral effects of p,p'-DDT but not of chlordecone. ( Hong, JS; Hudson, PM; Tilson, HA, 1986)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199021 (65.63)18.7374
1990's5 (15.63)18.2507
2000's4 (12.50)29.6817
2010's2 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kolasiewicz, W1
Kuter, K1
Berghauzen, K1
Nowak, P1
Schulze, G1
Ossowska, K1
Okamoto, R1
Itoh, Y1
Murata, Y1
Kobayashi, D1
Hosoi, M1
Mine, K1
Ricaurte, GA1
Yuan, J1
Hatzidimitriou, G1
Cord, BJ1
McCann, UD1
Mehta, H1
Saravanan, KS1
Mohanakumar, KP2
Arshaduddin, M1
Al Kadasah, S1
Biary, N1
Al Deeb, S1
Al Moutaery, K1
Tariq, M1
Kitamura, Y1
Shibata, K1
Akiyama, K1
Kimoto, S1
Fujitani, Y1
Kitagawa, K1
Kanzaki, H1
Ouchida, M1
Shimizu, K1
Kawasaki, H1
Sendo, T1
Gomita, Y1
Yamazaki, M1
Suzuki, S1
Ozaki, N1
Hong, JS2
Tilson, HA2
Uphouse, LL1
Gerhart, J1
Wilson, WE1
Fernando, JC1
Hoskins, BH1
Ho, IK1
Mohanty, S1
Ganguly, DK1
Nagao, T1
Ohshimo, T1
Mitsunobu, K1
Sato, M1
Otsuki, S1
Cox, B1
Tha, SJ1
Oelszner, W1
Funk, KF1
Staib, AH1
Westermann, KH1
Dohi, T1
Tsujimoto, A1
Growdon, JH1
Lenman, JA1
Turnbull, MJ1
Reid, A1
Fleming, AM1
McLellan, DL1
Chalmers, RJ1
Johnson, RH1
Squires, RF1
Lassen, JB1
García Ruiz, PJ1
Mena, MA1
Peñafiel, N1
De Yébenes, JG1
Ray, SK1
Poddar, MK1
Wieland, S1
Kreider, MS1
McGonigle, P1
Lucki, I1
Nagata, R1
Izumi, K1
Hudson, PM1
Coppen, A1
Metcalfe, M1
Carroll, JD1
Morris, JG1
Peters, DA1
Hrdina, PD1
Singhal, RL1
Ling, GM1
Tourian, AY1
Curzon, G3
Johannsson, B1
Roos, BE1
Guilleminault, C1
Tharp, BR1
Cousin, D1
Chase, TN1
Woods, AC1
Glaubiger, GA1
Parkes, JD1
Marsden, CD1
Rees, JE1
Kantamaneni, BD2
Knill-Jones, R1
Akbar, A1
Das, S1
Kataria, M1
Claveria, LE1
Harrison, MJ1

Trials

4 trials available for hydroxyindoleacetic acid and Tremor

ArticleYear
Clinical and pharmacological evaluation of the effects of piribedil in patients with parkinsonism.
    Acta neurologica Scandinavica, 1975, Volume: 51, Issue:1

    Topics: Aged; Antiparkinson Agents; Chorea; Clinical Trials as Topic; Confusion; Dioxoles; Dopamine; Drug Ev

1975
Levodopa and L-tryptophan therapy in Parkinsonism.
    Lancet (London, England), 1972, Mar-25, Volume: 1, Issue:7752

    Topics: Aged; Depression; Dihydroxyphenylalanine; Female; Gait; Homovanillic Acid; Humans; Hydroxyindoleacet

1972
Administration of 5-hydroxy-L-tryptophan to individuals with Huntington's chorea.
    Neurology, 1972, Volume: 22, Issue:11

    Topics: 5-Hydroxytryptophan; Adult; Brain; Evaluation Studies as Topic; Female; Humans; Huntington Disease;

1972
Parkinson disease treated with a suspected dopamine receptor agonist.
    Archives of neurology, 1974, Volume: 30, Issue:5

    Topics: Adult; Aged; Amantadine; Aromatic Amino Acid Decarboxylase Inhibitors; Benztropine; Dihydroxyphenyla

1974

Other Studies

28 other studies available for hydroxyindoleacetic acid and Tremor

ArticleYear
6-OHDA injections into A8-A9 dopaminergic neurons modelling early stages of Parkinson's disease increase the harmaline-induced tremor in rats.
    Brain research, 2012, Oct-05, Volume: 1477

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Central Nervous System Stimulants; Cereb

2012
Reduction of group II metabotropic glutamate receptors during development of benzodiazepine dependence.
    Pharmacology, 2013, Volume: 91, Issue:3-4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzodiazepines; Cerebral Cortex; Dopamine; Flumazenil; GAB

2013
RETRACTED: Severe dopaminergic neurotoxicity in primates after a common recreational dose regimen of MDMA ("ecstasy").
    Science (New York, N.Y.), 2002, 09-27, Volume: 297, Issue:5590

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Autoradiography; Axons; Brain; Carrier Proteins; Corpus Str

2002
Serotonin synthesis inhibition in olivo-cerebellar system attenuates harmaline-induced tremor in Swiss albino mice.
    Behavioural brain research, 2003, Oct-17, Volume: 145, Issue:1-2

    Topics: Animals; Behavior, Animal; Brain Chemistry; Cerebellum; Chromatography, High Pressure Liquid; Dopami

2003
Citalopram, a selective serotonin reuptake inhibitor augments harmaline-induced tremor in rats.
    Behavioural brain research, 2004, Aug-12, Volume: 153, Issue:1

    Topics: Analysis of Variance; Animals; Behavior, Animal; Brain Chemistry; Central Nervous System Stimulants;

2004
Increased DOI-induced wet-dog shakes in adrenocorticotropic hormone-treated rats are not affected by chronic imipramine treatment: possible involvement of enhanced 5-HT(2A)-receptor expression in the frontal cortex.
    Journal of pharmacological sciences, 2008, Volume: 106, Issue:1

    Topics: Adrenocorticotropic Hormone; Amphetamines; Animals; Antidepressive Agents, Tricyclic; Binding Sites;

2008
Biochemical investigation on the abnormal behaviors induced by fumitremorgin A, a tremorgenic mycotoxin to mice.
    Journal of pharmacobio-dynamics, 1983, Volume: 6, Issue:10

    Topics: Animals; Behavior, Animal; Brain; Brain Chemistry; Hydroxyindoleacetic Acid; Indenes; Male; Mice; Se

1983
Effects of chlordecone exposure on brain neurotransmitters: possible involvement of the serotonin system in chlordecone-elicited tremor.
    Toxicology and applied pharmacology, 1984, Volume: 73, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Body Temperature; Brain Chemistry; Chlordecone; Corpus Stri

1984
A striatal serotonergic involvement in the behavioural effects of anticholinesterase organophosphates.
    European journal of pharmacology, 1984, Feb-10, Volume: 98, Issue:1

    Topics: Animals; Atropine; Behavior, Animal; Cholinesterase Inhibitors; Corpus Striatum; Drug Interactions;

1984
Neonatal treatment with 5-HT antiserum alters 5-HT metabolism and function in adult rats.
    Neuroreport, 1995, Dec-29, Volume: 7, Issue:1

    Topics: Animals; Animals, Newborn; Basal Ganglia; Brain; Hydroxyindoleacetic Acid; Immune Sera; Pain; Rats;

1995
Cerebrospinal fluid monoamine metabolites and cyclic nucleotides in chronic schizophrenic patients with tardive dyskinesia or drug-induced tremor.
    Biological psychiatry, 1979, Volume: 14, Issue:3

    Topics: Adult; Chronic Disease; Cyclic AMP; Cyclic GMP; Cyproheptadine; Dyskinesia, Drug-Induced; Female; Ho

1979
Amantadin e tremor, a 5-hydroxytryptamine-mediated response?
    European journal of pharmacology, 1975, Volume: 30, Issue:2

    Topics: Amantadine; Animals; Brain; Brain Chemistry; Fenclonine; Hydroxyindoleacetic Acid; Mice; Mice, Inbre

1975
Serotonin content in the central nervous system of rats and cholinergic tremor.
    Polish journal of pharmacology and pharmacy, 1975, Volume: 27, Issue:Suppl

    Topics: Animals; Brain; Brain Chemistry; Female; Fenclonine; Hydroxyindoleacetic Acid; Oxotremorine; Parasym

1975
Possible mechanisms of sustained tremor induction by nicotine in pilocarpine treated animals.
    Archives internationales de pharmacodynamie et de therapie, 1978, Volume: 235, Issue:1

    Topics: Animals; Brain; Corpus Striatum; Dopamine; Fenclonine; Hemicholinium 3; Homovanillic Acid; Hydroxyin

1978
Postural changes, tremor, and myoclonus in the rat immediately following injections of p-chloromaphetamine.
    Neurology, 1977, Volume: 27, Issue:11

    Topics: Amphetamines; Animals; Dose-Response Relationship, Drug; Hydroxyindoleacetic Acid; Male; Motor Activ

1977
Urinary monoamine metabolite excretion in disorders of movement. Effects of amantadine and levodopa.
    Journal of the neurological sciences, 1977, Volume: 32, Issue:2

    Topics: Amantadine; Chorea; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Methylhistamines;

1977
The inhibition of A and B forms of MAO in the production of a characteristic behabioural syndrome in rats after 1-tryptophan loading.
    Psychopharmacologia, 1975, Volume: 41, Issue:2

    Topics: Alkynes; Animals; Brain Chemistry; Clorgyline; Drug Synergism; Humans; Hydroxyindoleacetic Acid; Hyp

1975
Cinnarizine-induced parkinsonism in primates.
    Clinical neuropharmacology, 1992, Volume: 15, Issue:2

    Topics: Animals; Biogenic Monoamines; Cinnarizine; Disease Models, Animal; Dopamine; Haplorhini; Homovanilli

1992
Interaction of central serotonin and dopamine in the regulation of carbaryl-induced tremor.
    European journal of pharmacology, 1990, Jun-08, Volume: 181, Issue:3

    Topics: 5-Hydroxytryptophan; Acetylcholinesterase; Animals; Atropine; Behavior, Animal; Brain Chemistry; Bro

1990
Destruction of the nucleus raphe obscurus and potentiation of serotonin-mediated behaviors following administration of the neurotoxin 3-acetylpyridine.
    Brain research, 1990, Jun-18, Volume: 520, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature Regulation; Brain; Dose-Response R

1990
Veratramine-induced behavior associated with serotonergic hyperfunction in mice.
    Japanese journal of pharmacology, 1991, Volume: 55, Issue:1

    Topics: 5,6-Dihydroxytryptamine; Animals; Brain Chemistry; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbre

1991
5,5-Diphenylhydantoin antagonizes neurochemical and behavioral effects of p,p'-DDT but not of chlordecone.
    Journal of neurochemistry, 1986, Volume: 47, Issue:6

    Topics: Animals; Brain Chemistry; Brain Stem; Caudate Nucleus; Chlordecone; DDT; Hippocampus; Hydroxyindolea

1986
The role of brain serotonin in DDT-induced hyperpyrexia.
    Journal of neurochemistry, 1972, Volume: 19, Issue:4

    Topics: Animals; Brain; Brain Stem; DDT; Fenclonine; Fever; Fluorine; Hydroxyindoleacetic Acid; Male; Pargyl

1972
Involuntary movements other than Parkinsonism: biochemical aspects.
    Proceedings of the Royal Society of Medicine, 1973, Volume: 66, Issue:9

    Topics: Acute Disease; Animals; Athetosis; Basal Ganglia; Brain; Dopamine; Fecal Incontinence; Homovanillic

1973
5-Hydroxyindoleacetic acid and homovanillic acid in cerebrospinal fluid of patients with neurological diseases.
    European neurology, 1974, Volume: 11, Issue:1

    Topics: Adult; Brain Neoplasms; Central Nervous System Diseases; Cerebellar Ataxia; Cerebrovascular Disorder

1974
HVA and 5HIAA CSF measurements and 5HTP trials in some patients with involuntary movements.
    Journal of the neurological sciences, 1973, Volume: 18, Issue:4

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Chorea; Dopamine; Dystonia Musculorum Deformans; Femal

1973
Parkinson's disease, cerebral arteriosclerosis, and senile dementia. Clinical features and response to levodopa.
    The Quarterly journal of medicine, 1974, Volume: 43, Issue:169

    Topics: Aged; Dementia; Dihydroxyphenylalanine; Electroencephalography; Female; Gait; Homovanillic Acid; Hum

1974
Amine metabolites in the cerebrospinal fluid of patients with disseminated sclerosis.
    Journal of neurology, neurosurgery, and psychiatry, 1974, Volume: 37, Issue:6

    Topics: Cerebellar Diseases; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Multiple Sclerosis; Phenyl

1974