hydroxyindoleacetic acid has been researched along with Tics in 2 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
Tics: Habitual, repeated, rapid contraction of certain muscles, resulting in stereotyped individualized actions that can be voluntarily suppressed for only brief periods. They often involve the face, vocal cords, neck, and less often the extremities. Examples include repetitive throat clearing, vocalizations, sniffing, pursing the lips, and excessive blinking. Tics tend to be aggravated by emotional stress. When frequent they may interfere with speech and INTERPERSONAL RELATIONS. Conditions which feature frequent and prominent tics as a primary manifestation of disease are referred to as TIC DISORDERS. (From Adams et al., Principles of Neurology, 6th ed, pp109-10)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Many studies have indicated that a variety of neurotransmitters are implicated in the pathophysiology of Tourette syndrome (TS), including dopamine (DA), serotonin (5-TH), homovanillic acid (HVA), and gamma-amino butyric acid (GABA)." | 5.16 | Effects of Chinese herbal medicine Ningdong granule on regulating dopamine (DA)/serotonin (5-TH) and gamma-amino butyric acid (GABA) in patients with Tourette syndrome. ( Li, A; Li, J; Qi, F; Wang, S; Zhao, L, 2012) |
| "Nicotine appears to ameliorate the tics of Tourette syndrome." | 3.71 | Effects of nicotine on head-shakes and tryptophan metabolites. ( Gaynor, CM; Handley, SL, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, S | 1 |
| Qi, F | 1 |
| Li, J | 1 |
| Zhao, L | 1 |
| Li, A | 1 |
| Gaynor, CM | 1 |
| Handley, SL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Double-Blind, Placebo-Controlled Trial Evaluating the Efficacy and Safety of Yi-Gan San in Children and Adolescents With Tourette's Disorder[NCT03564132] | Phase 2 | 38 participants (Actual) | Interventional | 2018-06-16 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for hydroxyindoleacetic acid and Tics
| Article | Year |
|---|---|
Effects of Chinese herbal medicine Ningdong granule on regulating dopamine (DA)/serotonin (5-TH) and gamma-amino butyric acid (GABA) in patients with Tourette syndrome.
Topics: Adolescent; Child; Dopamine; Drugs, Chinese Herbal; Enzyme-Linked Immunosorbent Assay; Female; gamma | 2012 |
1 other study available for hydroxyindoleacetic acid and Tics
| Article | Year |
|---|---|
Effects of nicotine on head-shakes and tryptophan metabolites.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Head Movements; Hydroxyindoleacetic Acid; Indophen | 2001 |