Page last updated: 2024-10-21

hydroxyindoleacetic acid and Supranuclear Palsy, Progressive

hydroxyindoleacetic acid has been researched along with Supranuclear Palsy, Progressive in 3 studies

(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.

Supranuclear Palsy, Progressive: A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al., Principles of Neurology, 6th ed, pp1076-7)

Research Excerpts

ExcerptRelevanceReference
"Results of long-term administration of L-threo-3,4-dihydroxyphenylserine (L-DOPS), a synthetic precursor of noradrenaline, in a patient with freezing gait and pure akinesia are reported."1.30Result of long-term administration of L-threo-3,4-dihydroxyphenylserine in patients with pure akinesia as an early symptom of progressive supranuclear palsy. ( Fujii, S; Hatanaka, Y; Yamamoto, M, 1997)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Kaiserova, M1
Chudackova, M1
Prikrylova Vranova, H1
Mensikova, K1
Kastelikova, A1
Stejskal, D1
Kanovsky, P1
Yamamoto, M2
Fujii, S1
Hatanaka, Y1
Ujike, H1
Kohira, I1
Ogasawara, N1
Ogawa, N1

Other Studies

3 other studies available for hydroxyindoleacetic acid and Supranuclear Palsy, Progressive

ArticleYear
Cerebrospinal Fluid Levels of 5-Hydroxyindoleacetic Acid in Parkinson's Disease and Atypical Parkinsonian Syndromes.
    Neuro-degenerative diseases, 2021, Volume: 21, Issue:1-2

    Topics: Diagnosis, Differential; Humans; Hydroxyindoleacetic Acid; Multiple System Atrophy; Parkinson Diseas

2021
Result of long-term administration of L-threo-3,4-dihydroxyphenylserine in patients with pure akinesia as an early symptom of progressive supranuclear palsy.
    Clinical neuropharmacology, 1997, Volume: 20, Issue:4

    Topics: Antiparkinson Agents; Droxidopa; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol;

1997
[CSF monoamine metabolites in patients with progressive supranuclear palsy].
    Rinsho shinkeigaku = Clinical neurology, 1992, Volume: 32, Issue:3

    Topics: Aged; Biogenic Monoamines; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxy

1992