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hydroxyindoleacetic acid and Scleroderma, Systemic

hydroxyindoleacetic acid has been researched along with Scleroderma, Systemic in 5 studies

(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.

Scleroderma, Systemic: A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.

Research Excerpts

ExcerptRelevanceReference
"An association between the ingestion tryptophan and a syndrome characterized by scleroderma-like skin abnormalities, fasciitis, and eosinophilia has recently been recognized in the United States."7.68Scleroderma, fasciitis, and eosinophilia associated with the ingestion of tryptophan. ( Heyes, MP; Maize, JC; Quearry, B; Silver, RM; Sternberg, EM; Vionnet-Fuasset, M, 1990)
"An association between the ingestion tryptophan and a syndrome characterized by scleroderma-like skin abnormalities, fasciitis, and eosinophilia has recently been recognized in the United States."3.68Scleroderma, fasciitis, and eosinophilia associated with the ingestion of tryptophan. ( Heyes, MP; Maize, JC; Quearry, B; Silver, RM; Sternberg, EM; Vionnet-Fuasset, M, 1990)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
TUFFANELLI, DL1
Stachów, A2
Jabłońska, S1
Skiendzielewska, A2
Kreysel, HW1
Meyerhoff, K1
Kimmig, J1
Jablonska, S1
Silver, RM1
Heyes, MP1
Maize, JC1
Quearry, B1
Vionnet-Fuasset, M1
Sternberg, EM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
L-5-Hydroxy-Tryptophan-Related Eosinophilia-Myalgia Syndrome (EMS): Clinical Patient Evaluation[NCT00001918]20 participants Observational1999-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

5 other studies available for hydroxyindoleacetic acid and Scleroderma, Systemic

ArticleYear
URINARY 5-HYDROXYINDOLEACETIC ACID EXCRETION IN SCLERODERMA.
    The Journal of investigative dermatology, 1963, Volume: 41

    Topics: Body Fluids; Hydroxyindoleacetic Acid; Indoleacetic Acids; Scleroderma, Systemic; Urine

1963
Biogenic amines derived from tryptophan in systemic and cutaneous scleroderma.
    Acta dermato-venereologica, 1979, Volume: 59, Issue:1

    Topics: Colorimetry; Female; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Male; Monoamine Oxidase;

1979
[Tryptophan-load in progressive scleroderma (author's transl)].
    Klinische Wochenschrift, 1976, Sep-15, Volume: 54, Issue:18

    Topics: 3-Hydroxyanthranilic Acid; Female; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Kynurenine;

1976
5-Hydroxytryptamine and tryptamine pathways in scleroderma.
    The British journal of dermatology, 1977, Volume: 97, Issue:2

    Topics: Adolescent; Adult; Aged; Female; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Indoles; Male

1977
Scleroderma, fasciitis, and eosinophilia associated with the ingestion of tryptophan.
    The New England journal of medicine, 1990, Mar-29, Volume: 322, Issue:13

    Topics: Adult; Aged; Eosinophilia; Fascia; Fasciitis; Female; Humans; Hydroxyindoleacetic Acid; Kynurenine;

1990