hydroxyindoleacetic acid has been researched along with Schizophrenia in 242 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The introduction of the atypical neuroleptic, clozapine, has had widespread influence not only on the treatment of the seriously mentally ill patient, but also on new drug development and on hypotheses of the pathophysiology of schizophrenia." | 9.07 | Predictors of clozapine response in schizophrenia. ( Hsiao, JK; Litman, RE; Owen, RR; Pickar, D; Su, TP, 1994) |
| "Twenty-one patients with schizophrenia who met criteria for neuroleptic treatment resistance or intolerance participated in a crossover, placebo-controlled, double-blind comparison of long-term typical neuroleptic and clozapine treatment." | 9.07 | Clinical and biologic response to clozapine in patients with schizophrenia. Crossover comparison with fluphenazine. ( Gutierrez, R; Konicki, E; Litman, RE; Owen, RR; Pickar, D; Rapaport, MH, 1992) |
| "In the week prior to discontinuation of haloperidol treatment, global behavioral ratings and a lumbar puncture for cerebrospinal fluid monoamine metabolities were obtained in 88 patients with chronic schizophrenia." | 7.69 | Behavioral vs biochemical prediction of clinical stability following haloperidol withdrawal in schizophrenia. ( Gilbertson, MW; Gurklis, JA; Kelley, ME; Peters, JL; van Kammen, DP; Yao, JK, 1995) |
| "Increased noradrenergic activity during chronic dopamine blockade may be an episode marker and may predict relapse within 6 weeks following haloperidol withdrawal in schizophrenia." | 7.69 | Noradrenergic activity and prediction of psychotic relapse following haloperidol withdrawal in schizophrenia. ( Agren, H; Gurklis, J; O'Connor, DT; Peters, JL; van Kammen, DP; Yao, JK, 1994) |
| "The efficacy of mianserin as a supplement in treating chronic schizophrenia was tested in 20 inpatients with schizophrenia who were receiving fixed doses of neuroleptics." | 7.68 | Effects of mianserin on negative symptoms in schizophrenia. ( Imai, T; Kai, S; Kajimura, N; Kaneyuki, H; Mizuki, Y; Suetsugi, M; Yamada, M, 1990) |
| "Low concentrations of the serotonin metabolite 5-hydroxyindoleacetic acid (5-HIAA) in cerebrospinal fluid (CSF) are associated with suicidal behaviour in patients with depressive illness, but studies of the relation between CSF 5-HIAA and suicide in schizophrenia have been inconclusive and have not included long-term follow-up." | 7.68 | 5-Hydroxyindoleacetic acid in cerebrospinal fluid and prediction of suicidal behaviour in schizophrenia. ( Cooper, SJ; Kelly, CB; King, DJ, 1992) |
| "Large doses (960 to 3200 mg/day) of propranolol were taken by eight patients with chronic schizophrenia in a double-blind therapeutic trial." | 7.67 | Effect of propranolol on monoamine metabolites in cerebrospinal fluid of patients with chronic schizophrenia. ( Linnoila, M; Ninan, PT; Scheinin, M; van Kammen, DP, 1984) |
| "Cerebrospinal fluid 5-hydroxyindoleacetic acid and total blood serotonin levels were measured simultaneously in 11 female patients with delirium tremens and nine schizophrenic women with clozapine-induced acute delirium." | 7.66 | Comparative simultaneous measurement of cerebrospinal fluid 5-hydroxyindoleacetic acid and blood serotonin levels in delirium tremens and clozapine-induced delirious reaction. ( Banki, CM; Vojnik, M, 1978) |
| "Schizophrenia is characterized by complex and dynamically interacting perturbations in multiple neurochemical systems." | 5.36 | Altered interactions of tryptophan metabolites in first-episode neuroleptic-naive patients with schizophrenia. ( Dougherty, GG; Kaddurah-Daouk, R; Keshavan, MS; Krishnan, RR; Matson, WR; McEvoy, J; Montrose, DM; Reddy, RD; Rozen, S; Yao, JK, 2010) |
| "1." | 5.29 | Effectiveness of concomitant setiptiline maleate (Tecipul) on negative symptoms of schizophrenia. ( Inanaga, K; Kuniyoshi, M; Miura, C; Nakamura, J, 1994) |
| "Twenty-one patients with schizophrenia who met criteria for neuroleptic treatment resistance or intolerance participated in a crossover, placebo-controlled, double-blind comparison of long-term typical neuroleptic and clozapine treatment." | 5.07 | Clinical and biologic response to clozapine in patients with schizophrenia. Crossover comparison with fluphenazine. ( Gutierrez, R; Konicki, E; Litman, RE; Owen, RR; Pickar, D; Rapaport, MH, 1992) |
| "The introduction of the atypical neuroleptic, clozapine, has had widespread influence not only on the treatment of the seriously mentally ill patient, but also on new drug development and on hypotheses of the pathophysiology of schizophrenia." | 5.07 | Predictors of clozapine response in schizophrenia. ( Hsiao, JK; Litman, RE; Owen, RR; Pickar, D; Su, TP, 1994) |
| "Four patients with chronic schizophrenia of stationary character were studied in order to titrate the lowest dose of thioridazine necessary for symptomatic control when the drug is given in combination with the inhibitor of catecholamine synthesis, metyrosine." | 5.04 | Potentiation by metyrosine of thioridazine effects in chronic schizophrenics. A long-term trial using double-blind crossover technique. ( Carlsson, A; Roos, BE; Skott, A; Wålinder, J, 1976) |
| "Metabolism of the monoamines dopamine, serotonin and noradrenaline, is altered in the central nervous system of people with schizophrenia, and their major metabolites homovanillic acid (HVA), 5-hydroxyindoleacetic acid (5-HIAA) and 3-methoxy-4-hydroxyphenylglycol (MHPG), respectively, have been intensively studied as indirect measures of these neurotransmitters in cerebrospinal fluid (CSF)." | 3.88 | No major influence of regular tobacco smoking on cerebrospinal fluid monoamine metabolite concentrations in patients with psychotic disorder and healthy individuals. ( Agartz, I; Andreou, D; Hjärpe, J; Jönsson, EG; Sedvall, GC; Söderman, E, 2018) |
| "We have previously found that repeated phencyclidine (PCP) treatment enhances the immobility induced by forced swimming and suggested that this behavioral change could be used as a model of the negative symptoms, particularly depression, of schizophrenia." | 3.69 | Effects of antidepressants on phencyclidine-induced enhancement of immobility in a forced swimming test in mice. ( Furukawa, H; Mamiya, T; Nabeshima, T; Noda, Y, 1997) |
| "In the week prior to discontinuation of haloperidol treatment, global behavioral ratings and a lumbar puncture for cerebrospinal fluid monoamine metabolities were obtained in 88 patients with chronic schizophrenia." | 3.69 | Behavioral vs biochemical prediction of clinical stability following haloperidol withdrawal in schizophrenia. ( Gilbertson, MW; Gurklis, JA; Kelley, ME; Peters, JL; van Kammen, DP; Yao, JK, 1995) |
| "Increased noradrenergic activity during chronic dopamine blockade may be an episode marker and may predict relapse within 6 weeks following haloperidol withdrawal in schizophrenia." | 3.69 | Noradrenergic activity and prediction of psychotic relapse following haloperidol withdrawal in schizophrenia. ( Agren, H; Gurklis, J; O'Connor, DT; Peters, JL; van Kammen, DP; Yao, JK, 1994) |
| "Low concentrations of the serotonin metabolite 5-hydroxyindoleacetic acid (5-HIAA) in cerebrospinal fluid (CSF) are associated with suicidal behaviour in patients with depressive illness, but studies of the relation between CSF 5-HIAA and suicide in schizophrenia have been inconclusive and have not included long-term follow-up." | 3.68 | 5-Hydroxyindoleacetic acid in cerebrospinal fluid and prediction of suicidal behaviour in schizophrenia. ( Cooper, SJ; Kelly, CB; King, DJ, 1992) |
| "In 8 cases of typical neuroleptic malignant syndrome (NMS), homovanillic acid (HVA), 5-hydroxyindole acetic acid (5-HIAA), noradrenaline (NA), and 3-methoxy-4-hydroxyphenylethyleneglycol (MHPG) levels in the cerebrospinal fluid (CSF) were assayed during both the active phase of NMS and after recovery." | 3.68 | Neuroleptic malignant syndrome: a study of CSF monoamine metabolism. ( Ishiguro, T; Nisijima, K, 1990) |
| "The efficacy of mianserin as a supplement in treating chronic schizophrenia was tested in 20 inpatients with schizophrenia who were receiving fixed doses of neuroleptics." | 3.68 | Effects of mianserin on negative symptoms in schizophrenia. ( Imai, T; Kai, S; Kajimura, N; Kaneyuki, H; Mizuki, Y; Suetsugi, M; Yamada, M, 1990) |
| "Lateral ventricle enlargement in schizophrenia has been positively correlated with poor premorbid competence, negative symptoms, and poor treatment response and negatively correlated with concentrations of homovanillic acid (HVA), a dopaminergic metabolite." | 3.68 | Lateral ventricle-brain ratio and balance between CSF HVA and 5-HIAA in schizophrenia. ( Caudle, J; Eccard, M; Jewart, RD; Lewine, RR; Pollard, W; Risby, E; Risch, SC; Stipetic, M, 1991) |
| "Large doses (960 to 3200 mg/day) of propranolol were taken by eight patients with chronic schizophrenia in a double-blind therapeutic trial." | 3.67 | Effect of propranolol on monoamine metabolites in cerebrospinal fluid of patients with chronic schizophrenia. ( Linnoila, M; Ninan, PT; Scheinin, M; van Kammen, DP, 1984) |
| " Lumbar cerebrospinal fluid (CSF) neurotransmitter metabolite levels for homovanillic acid (HVA), 5-hydroxyindoleacetic acid (5-HIAA), and 3-methoxy-4-hydroxyphenyl glycol (MHPG) were determined in patients with schizophrenia and Alzheimer's disease." | 3.67 | Seasonal variations of human lumbar CSF neurotransmitter metabolite concentrations. ( Davis, KL; Losonczy, MF; Mohs, RC, 1984) |
| "5-Hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) were measured in the spinal fluid of 45 women hospitalized in a psychiatric department for major depression (14 cases), schizophrenia (18 cases) and alcohol dependence (13 cases)." | 3.66 | Relationship between cerebrospinal fluid amine metabolites, neuroendocrine findings and personality dimensions (Marke-Nyman scale factors) in psychiatric patients. ( Arató, M; Banki, CM, 1983) |
| "5-Hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) were measured in the lumbar cerebrospinal fluid of 57 drug-free female patients with DSM-III diagnoses of major unipolar or bipolar depression (n = 14), schizophrenic disorder (n = 18), alcohol dependence (n = 13) and a group of other disorders (n = 12)." | 3.66 | Amine metabolites and neuroendocrine responses related to depression and suicide. ( Arató, M; Banki, CM, 1983) |
| "Baseline concentrations of homovanillic acid (HVA), 5-hydroxyindole acetic acid (5-HIAA) and MHPG in the cerebrospinal fluid (CSF) were determined in 67 lobotomized and 30 non-lobotomized patients with chronic schizophrenia." | 3.66 | Monoamine metabolite levels in cerebrospinal fluid and brain atrophy in lobotomized schizophrenic patients. ( Hyyppä, S; Kampman, R; Myllylä, V; Ranta, P; Rimón, R; Roos, BE, 1979) |
| "Cerebrospinal fluid 5-hydroxyindoleacetic acid and total blood serotonin levels were measured simultaneously in 11 female patients with delirium tremens and nine schizophrenic women with clozapine-induced acute delirium." | 3.66 | Comparative simultaneous measurement of cerebrospinal fluid 5-hydroxyindoleacetic acid and blood serotonin levels in delirium tremens and clozapine-induced delirious reaction. ( Banki, CM; Vojnik, M, 1978) |
| "The authors report cerebrospinal fluid (CSF) concentrations of five monoamine metabolites before and after probenecid administration in normal subjects and patients with depression and schizophrenia." | 3.66 | CSF monoamine metabolites in depression and schizophrenia. ( Anderson, PJ; Barchas, JD; Berger, PA; Davis, KL; Faull, KF; Kilkowski, J; Kraemer, H, 1980) |
| "26 patients with a paranoid-hallucinatory syndrome were treated with a fixed daily dose of haloperidol." | 3.65 | Clinical and biochemical parameters during neuroleptic treatment. I. Investigations with haloperidol. ( Ackenheil, M; Eben, E; Hippius, H; Rüther, E; Schilkrut, R, 1976) |
| "The metabolites of serotonin, dopamine, and norepinephrine, 5-hydroxyindoleacetic acid (5HIAA), homovanillic acid (HVA), and 3-methoxy-4-hydroxy-phenylethylene glycol (MHPG), respectively, were studied in cerebrospinal fluid of patients with acute schizophrenia." | 3.65 | Cerebrospinal fluid amine metabolites in acute schizophrenia. ( Carpenter, WT; Fink, E; Goodwin, FK; Post, RM, 1975) |
| "Sulpiride was administered in three different daily dosages (starting with 400, 800 or 1200 mg) according to a double blind randomized administration schedule." | 2.66 | Monoamine metabolites and amino acids in serum from schizophrenic patients before and during sulpiride treatment. ( Alfredsson, G; Wiesel, FA, 1989) |
| "Sulpiride-treated patients with extrapyramidal side effects had significantly higher drug concentrations in serum." | 2.65 | Relationships between drug concentrations in serum and CSF, clinical effects and monoaminergic variables in schizophrenic patients treated with sulpiride or chlorpromazine. ( Alfredsson, G; Bjerkenstedt, L; Edman, G; Härnryd, C; Oxenstierna, G; Sedvall, G; Wiesel, FA, 1984) |
| "Patients with schizophrenia have higher rates of mortality than the general population." | 1.37 | Early death and CSF monoamine metabolites in schizophrenia spectrum psychosis. ( Carlborg, A; Jokinen, J; Jönsson, EG; Nordström, AL; Nordström, P, 2011) |
| "Schizophrenia is characterized by complex and dynamically interacting perturbations in multiple neurochemical systems." | 1.36 | Altered interactions of tryptophan metabolites in first-episode neuroleptic-naive patients with schizophrenia. ( Dougherty, GG; Kaddurah-Daouk, R; Keshavan, MS; Krishnan, RR; Matson, WR; McEvoy, J; Montrose, DM; Reddy, RD; Rozen, S; Yao, JK, 2010) |
| "1." | 1.29 | Effectiveness of concomitant setiptiline maleate (Tecipul) on negative symptoms of schizophrenia. ( Inanaga, K; Kuniyoshi, M; Miura, C; Nakamura, J, 1994) |
| "Schizophrenia is associated with multiple cognitive deficits which in turn may be related to abnormal dopamine (DA) function." | 1.29 | Neuropsychological correlates of central monoamine function in chronic schizophrenia: relationship between CSF metabolites and cognitive function. ( Apter, S; Davidson, M; Davis, KL; Harvey, PD; Kahn, RS; Keefe, RS; Mohs, RC; Neale, JM, 1994) |
| "Treatment with haloperidol normalized the low ratio." | 1.27 | Preliminary evidence of reduced combined output of dopamine and its metabolites in chronic schizophrenia. ( Bigelow, LB; Karoum, F; Karson, CN; Lawson, WB; Wyatt, RJ, 1987) |
| "Homovanillic acid accumulation was decreased in this group." | 1.26 | Dopamine, noradrenaline and serotonin spinal fluid metabolites in temporal lobe epileptic patients with schizophrenic symptomatology. ( Peters, JG, 1979) |
| "Thioridazine was administered to 14 patients diagnosed as within the "schizophrenic spectrum" with the result that substantial improvement in psychotic symptoms was achieved while significant extrapyramidal side effects occurred in only 1 patients." | 1.25 | Thioridazine: central dopamine turnover and clinical effects of antipsychotic drugs. ( Bowers, MB, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 174 (71.90) | 18.7374 |
| 1990's | 46 (19.01) | 18.2507 |
| 2000's | 15 (6.20) | 29.6817 |
| 2010's | 6 (2.48) | 24.3611 |
| 2020's | 1 (0.41) | 2.80 |
| Authors | Studies |
|---|---|
| Shiga, T | 1 |
| Horikoshi, S | 2 |
| Kanno, K | 1 |
| Kanno-Nozaki, K | 2 |
| Hikita, M | 1 |
| Itagaki, S | 1 |
| Miura, I | 2 |
| Yabe, H | 2 |
| Hjärpe, J | 1 |
| Söderman, E | 1 |
| Andreou, D | 1 |
| Sedvall, GC | 3 |
| Agartz, I | 1 |
| Jönsson, EG | 4 |
| Curto, M | 1 |
| Lionetto, L | 1 |
| Fazio, F | 1 |
| Corigliano, V | 1 |
| Comparelli, A | 1 |
| Ferracuti, S | 1 |
| Simmaco, M | 1 |
| Nicoletti, F | 1 |
| Baldessarini, RJ | 1 |
| Watanabe, K | 1 |
| Mashiko, H | 1 |
| Niwa, S | 2 |
| Winter, C | 1 |
| Djodari-Irani, A | 1 |
| Sohr, R | 1 |
| Morgenstern, R | 1 |
| Feldon, J | 2 |
| Juckel, G | 1 |
| Meyer, U | 1 |
| Yao, JK | 4 |
| Dougherty, GG | 1 |
| Reddy, RD | 1 |
| Keshavan, MS | 1 |
| Montrose, DM | 1 |
| Matson, WR | 1 |
| Rozen, S | 1 |
| Krishnan, RR | 1 |
| McEvoy, J | 1 |
| Kaddurah-Daouk, R | 1 |
| Carlborg, A | 2 |
| Jokinen, J | 2 |
| Nordström, AL | 2 |
| Nordström, P | 2 |
| Nikisch, G | 1 |
| Baumann, P | 1 |
| Wiedemann, G | 1 |
| Kiessling, B | 1 |
| Weisser, H | 1 |
| Hertel, A | 1 |
| Yoshitake, T | 1 |
| Kehr, J | 1 |
| Mathé, AA | 3 |
| Aymard, N | 1 |
| Viala, A | 1 |
| Clement, MN | 1 |
| Jacquot, M | 1 |
| Vacheron, MN | 1 |
| Gauillard, J | 1 |
| Caroli, F | 1 |
| Oades, RD | 1 |
| Klimke, A | 1 |
| Henning, U | 1 |
| Rao, ML | 1 |
| Malone, KM | 1 |
| Waternaux, C | 1 |
| Haas, GL | 1 |
| Cooper, TB | 3 |
| Li, S | 1 |
| Mann, JJ | 2 |
| SANO, I | 1 |
| KAKIMOTO, Y | 1 |
| OKAMOTO, T | 1 |
| NAKAJIMA, H | 1 |
| KUDO, Y | 1 |
| VALCOURT, AJ | 1 |
| KOPIN, IJ | 1 |
| SKUGAREVSKII, AF | 1 |
| ALLEGRANZA, A | 3 |
| BOZZI, R | 4 |
| BRUNO, A | 4 |
| LEE, SJ | 3 |
| DEVITO, C | 1 |
| ALLERGRANZA, A | 1 |
| PELICIER, Y | 1 |
| Elman, I | 1 |
| Lukas, S | 1 |
| Shoaf, SE | 1 |
| Rott, D | 1 |
| Adler, C | 1 |
| Breier, A | 3 |
| van der Heijden, FM | 1 |
| Tuinier, S | 1 |
| Fekkes, D | 1 |
| Sijben, AE | 1 |
| Kahn, RS | 5 |
| Verhoeven, WM | 2 |
| Jacobsen, JP | 1 |
| Rodriguiz, RM | 1 |
| Mørk, A | 1 |
| Wetsel, WC | 1 |
| Bell, CJ | 1 |
| Hood, SD | 1 |
| Nutt, DJ | 1 |
| Brunelin, J | 1 |
| D'amato, T | 1 |
| van Os, J | 1 |
| Dalery, J | 1 |
| Suaud-Chagny, MF | 1 |
| Saoud, M | 1 |
| Tekes, K | 1 |
| Bourgeois, M | 1 |
| Henry, P | 1 |
| Toru, M | 1 |
| Ichikawa, H | 1 |
| Chen, YF | 2 |
| Domino, EF | 1 |
| Leckman, JF | 2 |
| Cohen, DJ | 2 |
| Shaywitz, BA | 2 |
| Caparulo, BK | 1 |
| Heninger, GR | 2 |
| Bowers, MB | 15 |
| Macfie, C | 1 |
| Wode-Helgodt, B | 2 |
| Sedvall, G | 15 |
| Gomes, UC | 1 |
| Shanley, BC | 1 |
| Potgieter, L | 1 |
| Roux, JT | 1 |
| Sturges, JS | 1 |
| Gamaleia, NB | 1 |
| Misionzhnik, EIu | 1 |
| Vertogradova, OP | 1 |
| Krasnov, VN | 1 |
| Salenko, BB | 1 |
| Rastogi, RB | 1 |
| Singhal, RL | 1 |
| Lapierre, YD | 1 |
| Nemtsov, AV | 1 |
| Kalinin, VV | 1 |
| Uytdenhoef, P | 1 |
| Linkowski, P | 1 |
| Mendlewicz, J | 1 |
| Reminiak, VI | 1 |
| Potkin, SG | 1 |
| Weinberger, DR | 2 |
| Linnoila, M | 13 |
| Wyatt, RJ | 6 |
| Wood, PL | 1 |
| Etienne, P | 1 |
| Lal, S | 1 |
| Gauthier, S | 1 |
| Cajal, S | 1 |
| Nair, NP | 1 |
| Buchsbaum, MS | 1 |
| Haier, RJ | 1 |
| Benson, KL | 2 |
| Zarcone, VP | 2 |
| Faull, KF | 11 |
| Barchas, JD | 4 |
| Berger, PA | 4 |
| King, DJ | 3 |
| Cooper, SJ | 3 |
| Liddle, J | 1 |
| Banki, CM | 7 |
| Arató, M | 6 |
| Papp, Z | 4 |
| Kurcz, M | 1 |
| Levy, MI | 1 |
| Davis, BM | 2 |
| Mohs, RC | 4 |
| Trigos, GC | 1 |
| Davis, KL | 7 |
| Magnusson, O | 1 |
| Fowler, CJ | 1 |
| Ross, SB | 2 |
| Schulman, A | 2 |
| Wetterberg, L | 1 |
| van Praag, HM | 4 |
| Bartfai, A | 2 |
| Levander, SE | 2 |
| Nybäck, H | 2 |
| Berggren, BM | 1 |
| Hindmarsh, T | 1 |
| Wiesel, FA | 8 |
| Ninan, PT | 4 |
| Scheinin, M | 4 |
| Waters, RN | 1 |
| Chang, WH | 1 |
| Bartko, J | 1 |
| van Kammen, DP | 12 |
| Cowdry, RW | 1 |
| Ebert, MH | 1 |
| Post, RM | 5 |
| Goodwin, FK | 7 |
| Javaid, JI | 1 |
| Liu, TS | 1 |
| Maas, JW | 1 |
| Davis, JM | 1 |
| Alfredsson, G | 2 |
| Bjerkenstedt, L | 7 |
| Edman, G | 3 |
| Härnryd, C | 5 |
| Oxenstierna, G | 3 |
| Gullberg, B | 4 |
| Bunney, WE | 2 |
| Jeste, DV | 1 |
| Doongaji, DR | 1 |
| van Ree, JM | 1 |
| Westenberg, HG | 2 |
| Krul, JM | 1 |
| Brouwer, GJ | 1 |
| Thijssen, JH | 1 |
| de Wied, D | 1 |
| Ceulemans, DL | 1 |
| Schalling, D | 2 |
| Losonczy, MF | 2 |
| Iselius, L | 1 |
| Oreland, L | 1 |
| Potter, WZ | 4 |
| Rainer, JD | 1 |
| Gerner, RH | 1 |
| Fairbanks, L | 1 |
| Anderson, GM | 1 |
| Young, JG | 1 |
| Hare, TA | 1 |
| Sethi, BB | 1 |
| Dube, S | 1 |
| Sharma, M | 1 |
| Kilkowski, J | 2 |
| Anderson, PJ | 2 |
| Kraemer, H | 2 |
| Faustman, WO | 4 |
| Ringo, DL | 2 |
| Kontur, PJ | 1 |
| al-Tikriti, M | 1 |
| Innis, RB | 1 |
| Roth, RH | 1 |
| Agren, H | 2 |
| O'Connor, DT | 2 |
| Gurklis, J | 1 |
| Peters, JL | 3 |
| Harvey, PD | 1 |
| Davidson, M | 3 |
| Keefe, RS | 1 |
| Apter, S | 2 |
| Neale, JM | 1 |
| de las Cuevas Castresana, C | 1 |
| González de Rivera, JL | 1 |
| Kuniyoshi, M | 1 |
| Nakamura, J | 1 |
| Miura, C | 1 |
| Inanaga, K | 1 |
| Breslin, NA | 1 |
| Suddath, RL | 1 |
| Bissette, G | 1 |
| Nemeroff, CB | 1 |
| Lowrimore, P | 1 |
| Pickar, D | 7 |
| Owen, RR | 2 |
| Litman, RE | 2 |
| Hsiao, JK | 3 |
| Su, TP | 1 |
| Szymanski, S | 1 |
| Lieberman, J | 2 |
| Pollack, S | 3 |
| Munne, R | 1 |
| Safferman, A | 1 |
| Kane, J | 2 |
| Kronig, M | 1 |
| Cooper, T | 2 |
| Kitaichi, K | 1 |
| Yamada, K | 1 |
| Hasegawa, T | 1 |
| Furukawa, H | 2 |
| Nabeshima, T | 2 |
| Risch, SC | 3 |
| Csernansky, JG | 4 |
| Newcomer, JW | 1 |
| Jackson, K | 1 |
| Lombrozo, L | 1 |
| Zipursky, R | 1 |
| Pfefferbaum, A | 2 |
| Kelley, ME | 1 |
| Gurklis, JA | 1 |
| Gilbertson, MW | 1 |
| Elliott, PJ | 1 |
| Knott, P | 1 |
| Stern, RG | 1 |
| Colison, J | 2 |
| Bartko, JJ | 1 |
| Doran, AR | 2 |
| Konicki, PE | 2 |
| Manji, HK | 1 |
| Lewine, RR | 2 |
| Roy, A | 6 |
| Kunz, M | 1 |
| Sikora, J | 1 |
| Krakowski, M | 1 |
| Convit, A | 1 |
| Volavka, J | 1 |
| Iqbal, N | 1 |
| Prell, GD | 1 |
| Green, JP | 1 |
| Elkashef, AM | 1 |
| Khandelwal, JK | 1 |
| Lawson, WB | 2 |
| Jaeger, AC | 1 |
| Kaufmann, CA | 1 |
| Kirch, DG | 1 |
| Fukuda, M | 1 |
| Hiramatsu, K | 1 |
| Hata, A | 1 |
| Nakagome, K | 1 |
| Iwanami, A | 1 |
| Honda, H | 1 |
| Tuckwell, HC | 1 |
| Koziol, JA | 1 |
| Noda, Y | 1 |
| Mamiya, T | 1 |
| Geijer, T | 1 |
| Gyllander, A | 1 |
| Terenius, L | 2 |
| Hatzimanolis, J | 1 |
| Lykouras, L | 1 |
| Markianos, M | 2 |
| Oulis, P | 1 |
| Wieselgren, IM | 2 |
| Lindström, LH | 5 |
| Chotai, J | 1 |
| Salander Renberg, E | 1 |
| Kullgren, G | 1 |
| Asberg, M | 2 |
| Murphy, CA | 1 |
| Pezze, M | 1 |
| Heidbreder, C | 1 |
| Kim, YK | 1 |
| Kim, L | 1 |
| Lee, MS | 1 |
| Scheepers, FE | 1 |
| Gispen-de Wied, CC | 1 |
| Curzon, G | 2 |
| Kantamaneni, BD | 2 |
| Bartlett, JR | 2 |
| Bridges, PK | 2 |
| Nagao, T | 1 |
| Ohshimo, T | 1 |
| Mitsunobu, K | 1 |
| Sato, M | 1 |
| Otsuki, S | 1 |
| Crow, TJ | 2 |
| Baker, HF | 2 |
| Cross, AJ | 1 |
| Joseph, MH | 1 |
| Lofthouse, R | 1 |
| Longden, A | 1 |
| Owen, F | 1 |
| Riley, GJ | 2 |
| Glover, V | 1 |
| Killpack, WS | 1 |
| Okasha, A | 2 |
| Eid, SZ | 2 |
| Bishry, Z | 2 |
| Lotaif, F | 2 |
| Gouda, JF | 2 |
| Jospeh, MH | 1 |
| Risby, D | 1 |
| Grimm, VE | 1 |
| Mileikovskii, IuA | 1 |
| Roccatagliata, G | 1 |
| Albano, C | 1 |
| Cocito, L | 1 |
| Maffini, M | 1 |
| Moore, D | 1 |
| Tarsy, D | 1 |
| Study, RE | 1 |
| Takahashi, R | 1 |
| Peters, JG | 1 |
| Rimón, R | 2 |
| Roos, BE | 8 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00004325] | 200 participants | Observational | 1988-12-31 | Completed | |||
| Imaging Framework for Testing GABAergic/Glutamatergic Drugs in Bipolar Alcoholics[NCT03220776] | Phase 2 | 54 participants (Actual) | Interventional | 2017-08-07 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Concentrations of GABA+, referenced to unsuppressed water and corrected for within-voxel CSF proportion, in dorsal anterior cingulate cortex measured via Proton Magnetic Resonance Spectroscopy (i.e., MEGA-PRESS). (NCT03220776)
Timeframe: Day 5 of each experimental condition
| Intervention | mmol/kg (Mean) |
|---|---|
| N-Acetylcysteine | 3.90 |
| Gabapentin | 3.93 |
| Placebo Oral Tablet | 3.73 |
Concentrations of Glx (i.e., glutamate + glutamine), referenced to unsuppressed water and corrected for within-voxel CSF proportion, in dorsal anterior cingulate cortex measured via Proton Magnetic Resonance Spectroscopy. (NCT03220776)
Timeframe: Day 5 of each experimental condition
| Intervention | mmol/kg (Mean) |
|---|---|
| N-Acetylcysteine | 21.59 |
| Gabapentin | 21.69 |
| Placebo Oral Tablet | 22.25 |
24 reviews available for hydroxyindoleacetic acid and Schizophrenia
| Article | Year |
|---|---|
Acute tryptophan depletion. Part II: clinical effects and implications.
Topics: Alleles; Alzheimer Disease; Autistic Disorder; Bipolar Disorder; Cognitive Behavioral Therapy; Depre | 2005 |
[Neurotransmitters and neuropeptides in schizophrenia].
Topics: Acetylcholine; Brain Chemistry; Endorphins; Enkephalins; Homovanillic Acid; Humans; Hydroxyindoleace | 1984 |
The year ... psychiatry.
Topics: Affective Symptoms; Behavior Therapy; Brain; Electroconvulsive Therapy; Humans; Hydroxyindoleacetic | 1980 |
[Biological methods of predicting the effectiveness of psychopharmacologic treatment of schizophrenia (review)].
Topics: Antipsychotic Agents; Apomorphine; Cyclic AMP; Drug Evaluation; Electroencephalography; Evoked Poten | 1981 |
Psychopathology: biological approaches.
Topics: Adoption; Adrenocorticotropic Hormone; Antipsychotic Agents; Brain; Dexamethasone; Diseases in Twins | 1983 |
Cerebrospinal fluid probenecid studies: a reinterpretation.
Topics: Biological Transport; Brain; Depressive Disorder; Dopamine; Homovanillic Acid; Humans; Hydroxyindole | 1983 |
Genetic studies of CSF monoamine metabolites.
Topics: Biogenic Amines; Blood Platelets; Dopamine beta-Hydroxylase; Female; Homovanillic Acid; Humans; Hydr | 1984 |
Psychotherapeutic drugs and biogenic amines. Current concepts and therapeutic implications.
Topics: Antidepressive Agents; Biogenic Amines; Dopamine; Humans; Hydroxyindoleacetic Acid; Mental Disorders | 1984 |
Genetic factors in depression and suicide.
Topics: Adoption; Bipolar Disorder; Depressive Disorder; Diseases in Twins; Electroencephalography; Family; | 1984 |
Markers in psychoses: studies from India.
Topics: Adrenal Cortex Hormones; Affective Disorders, Psychotic; Blood Platelets; Body Constitution; Chromos | 1984 |
[Etiology of schizophrenia: neurochemical aspects].
Topics: Antipsychotic Agents; Dopamine Antagonists; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Mon | 1994 |
The role of serotonin in schizophrenia.
Topics: Blood Platelets; Dopamine; Humans; Hydroxyindoleacetic Acid; Receptors, Serotonin; Schizophrenia; Se | 1995 |
On the concentration of 5-hydroxyindoleacetic acid in schizophrenia: a meta-analysis.
Topics: Acute Disease; Chronic Disease; Humans; Hydroxyindoleacetic Acid; Schizophrenia | 1996 |
[Amines in mental disorders (author's transl)].
Topics: Aggression; Biogenic Amines; Bipolar Disorder; Brain; Catecholamines; Dopamine; Emotions; Humans; Hy | 1977 |
Studies of amine metabolites in affective illness and in schizophrenia: a comparative analysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Antidepressive Agents, Tricyclic; Bipolar Disorder; Brain; Depressio | 1975 |
Structure-function relations in schizophrenia: brain morphology and neuropsychology.
Topics: Brain; Cerebral Ventricles; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Psych | 1992 |
Suicide and psychiatric patients.
Topics: Adult; Affective Disorders, Psychotic; Alcoholism; Blood Platelets; Emergency Services, Psychiatric; | 1985 |
Suicide: a review of new directions in research.
Topics: Adolescent; Adult; Aged; Alcoholism; Black or African American; Black People; Delusions; Depressive | 1986 |
Depression, attempted suicide, and suicide in patients with chronic schizophrenia.
Topics: Adolescent; Adult; Antidepressive Agents; Antipsychotic Agents; Atrophy; Brain; Chronic Disease; Del | 1986 |
Cerebrospinal fluid studies of monoamine metabolism in schizophrenia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Antipsychotic Agents; Catecholamines; Cyclic AMP; Dopamine; Dopamine | 1986 |
Neuropharmacology of S-adenosyl methionine.
Topics: Animals; Antidepressive Agents; Biogenic Amines; Brain; Dementia; Depressive Disorder; Epilepsy; Fol | 1986 |
A critical appraisal of CSF monoamine metabolite studies in schizophrenia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Biogenic Monoamines; Dopamine; Homovanillic Acid; Humans; Hydroxyind | 1988 |
A clinical perspective on the role of neurotransmitters in mental disorders.
Topics: Antidepressive Agents; Brain Chemistry; Cyclic AMP; Depressive Disorder; Dopamine; Electroconvulsive | 1985 |
Clinical psychiatry.
Topics: Ambulatory Care; Anxiety Disorders; Brain Chemistry; Child; Community Mental Health Services; Depres | 1969 |
22 trials available for hydroxyindoleacetic acid and Schizophrenia
| Article | Year |
|---|---|
Atypical antipsychotics and the relevance of glutamate and serotonin.
Topics: Adult; Analysis of Variance; Antipsychotic Agents; Case-Control Studies; Chromatography, High Pressu | 2004 |
Serotonergic response to stress: a protective factor against abnormal dopaminergic reactivity in schizophrenia?
Topics: Adult; Antimetabolites; Arousal; Cross-Over Studies; Deoxyglucose; Dopamine; Double-Blind Method; Fe | 2007 |
The effect of propranolol on CSF amine metabolites in psychiatric patients.
Topics: Adult; Chronic Disease; Clinical Trials as Topic; Female; Glycols; Homovanillic Acid; Humans; Hydrox | 1983 |
Relationships between drug concentrations in serum and CSF, clinical effects and monoaminergic variables in schizophrenic patients treated with sulpiride or chlorpromazine.
Topics: Adolescent; Adult; Chlorpromazine; Clinical Trials as Topic; Double-Blind Method; Female; Homovanill | 1984 |
Clinical, biochemical, and hormonal aspects of treatment with Des-tyr1-gamma-endorphin in schizophrenia.
Topics: Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Endorphins; Female; Growth Hormone | 1984 |
Predictors of clozapine response in schizophrenia.
Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Clozapine; Double-Blind Method; Female; Fluphen | 1994 |
The dopamine-serotonin relationship in clozapine response.
Topics: Adolescent; Adult; Antipsychotic Agents; Clozapine; Dopamine; Drug Resistance; Dyskinesia, Drug-Indu | 1993 |
Effects of raclopride treatment on plasma and CSF HVA: relationships with clinical improvement in male schizophrenics.
Topics: Adult; Dopamine Antagonists; Double-Blind Method; Homovanillic Acid; Humans; Hydroxyindoleacetic Aci | 1994 |
The effect of olanzapine treatment on monoamine metabolite concentrations in the cerebrospinal fluid of schizophrenic patients.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; M | 2001 |
Monoamine metabolite levels in cerebrospinal fluid of psychotic women treated with melperone or thiothixene.
Topics: Antipsychotic Agents; Butyrophenones; Clinical Trials as Topic; Double-Blind Method; Female; Glycols | 1977 |
Levels of HIAA and VMA in c.s.f. of schizophrenics before and after treatment.
Topics: Catecholamines; Dopamine Antagonists; Electroconvulsive Therapy; Female; Humans; Hydroxyindoleacetic | 1978 |
Tardive dyskinesia: a clinical test of the supersensitivity hypothesis.
Topics: Adult; Aged; Clinical Trials as Topic; Cyclic AMP; Depression; Dyskinesia, Drug-Induced; Female; Hom | 1979 |
Potentiation by metyrosine of thioridazine effects in chronic schizophrenics. A long-term trial using double-blind crossover technique.
Topics: Aged; Chronic Disease; Clinical Trials as Topic; Drug Synergism; Drug Therapy, Combination; Female; | 1976 |
Effect of chlorpromazine treatment on monoamine metabolite levels in cerebrospinal fluid of psychotic patients.
Topics: Adult; Aged; Chlorpromazine; Ethylene Glycols; Female; Homovanillic Acid; Humans; Hydroxyindoleaceti | 1977 |
Extrapyramidal reactions and amine metabolites in cerebrospinal fluid during haloperidol and clozapine treatment of schizophrenic patients.
Topics: Adult; Aged; Basal Ganglia Diseases; Clinical Trials as Topic; Clozapine; Dibenzazepines; Haloperido | 1975 |
Clinical and biologic response to clozapine in patients with schizophrenia. Crossover comparison with fluphenazine.
Topics: Adult; Antipsychotic Agents; Clozapine; Dopamine; Double-Blind Method; Female; Fluphenazine; Homovan | 1992 |
Hemodialysis in the treatment of a group of schizophrenic patients.
Topics: Adult; Cholesterol, HDL; Clinical Trials as Topic; Double-Blind Method; Female; Follow-Up Studies; H | 1985 |
Clonidine treatment of schizophrenia: can we predict treatment response?
Topics: Adult; Clinical Trials as Topic; Clonidine; Growth Hormone; Homovanillic Acid; Humans; Hydroxyindole | 1989 |
Melperone in the treatment of schizophrenia.
Topics: Antipsychotic Agents; Butyrophenones; Diazepam; Double-Blind Method; Drug Therapy, Combination; Homo | 1989 |
Monoamine metabolites and amino acids in serum from schizophrenic patients before and during sulpiride treatment.
Topics: Adolescent; Adult; Amino Acids; Biogenic Monoamines; Female; Glutamates; Glutamine; Homovanillic Aci | 1989 |
Behavioral changes of chronic schizophrenic patients given L-5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Administration, Oral; Adult; Brain; Carboxy-Lyases; Clinical Trials as Topic; H | 1972 |
5-Hydroxyindoleacetic acid (5HIAA) and homovanillic acid (HVA) following probenecid in acute psychotic patients treated with phenothiazines.
Topics: Clinical Trials as Topic; Depression; Female; Humans; Hydroxyindoleacetic Acid; Male; Phenothiazines | 1973 |
196 other studies available for hydroxyindoleacetic acid and Schizophrenia
| Article | Year |
|---|---|
Plasma levels of dopamine metabolite correlate with mismatch negativity in patients with schizophrenia.
Topics: Adult; Dopamine; Electroencephalography; Evoked Potentials; Evoked Potentials, Auditory; Female; Hom | 2020 |
No major influence of regular tobacco smoking on cerebrospinal fluid monoamine metabolite concentrations in patients with psychotic disorder and healthy individuals.
Topics: Adolescent; Adult; Biogenic Monoamines; Biomarkers; Female; Homovanillic Acid; Humans; Hydroxyindole | 2018 |
Serum xanthurenic acid levels: Reduced in subjects at ultra high risk for psychosis.
Topics: Adolescent; Adult; Disease Progression; Female; Humans; Hydroxyindoleacetic Acid; Kynurenic Acid; Ky | 2019 |
Associations between five-factor model of the Positive and Negative Syndrome Scale and plasma levels of monoamine metabolite in patients with schizophrenia.
Topics: Adult; Antipsychotic Agents; Chromatography, High Pressure Liquid; Female; Homovanillic Acid; Humans | 2015 |
Prenatal immune activation leads to multiple changes in basal neurotransmitter levels in the adult brain: implications for brain disorders of neurodevelopmental origin such as schizophrenia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Brain Diseases; Chromatography, High Press | 2009 |
Altered interactions of tryptophan metabolites in first-episode neuroleptic-naive patients with schizophrenia.
Topics: Adolescent; Adult; Antipsychotic Agents; Female; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; | 2010 |
CSF 5-HIAA, attempted suicide and suicide risk in schizophrenia spectrum psychosis.
Topics: Adult; Female; Follow-Up Studies; Humans; Hydroxyindoleacetic Acid; Male; Psychiatric Status Rating | 2009 |
Early death and CSF monoamine metabolites in schizophrenia spectrum psychosis.
Topics: Adult; Age Factors; Cause of Death; Cerebrospinal Fluid; Female; Follow-Up Studies; Homovanillic Aci | 2011 |
Quetiapine and norquetiapine in plasma and cerebrospinal fluid of schizophrenic patients treated with quetiapine: correlations to clinical outcome and HVA, 5-HIAA, and MHPG in CSF.
Topics: Adolescent; Adult; Biomarkers; Dibenzothiazepines; Female; Homovanillic Acid; Humans; Hydroxyindolea | 2010 |
Long-term pharmacoclinical follow-up in schizophrenic patients treated with risperidone. Plasma and red blood cell concentrations of risperidone and its 9-hydroxymetabolite and their relationship to whole blood serotonin and tryptophan, plasma homovanilli
Topics: Adult; Aged; Analysis of Variance; Biomarkers; Female; Follow-Up Studies; Homovanillic Acid; Humans; | 2002 |
Relations of clinical features, subgroups and medication to serum monoamines in schizophrenia.
Topics: Adult; Antipsychotic Agents; Biogenic Monoamines; Dopamine; Female; Homovanillic Acid; Humans; Hydro | 2002 |
Cigarette smoking, suicidal behavior, and serotonin function in major psychiatric disorders.
Topics: Adolescent; Adult; Aged; Comorbidity; Depressive Disorder; Female; Fenfluramine; Humans; Hydrocortis | 2003 |
[5-Hydroxyindoleacetic acid excretion in urine of schizophrenics with reference to effects of chlorpromazine and reserpine on serotonin metabolism].
Topics: Body Fluids; Chlorpromazine; Hydroxyindoleacetic Acid; Indoleacetic Acids; Reserpine; Schizophrenia; | 1957 |
Study of excretion of 5-hydroxyindoleacetic acid in mental patients.
Topics: Biological Transport; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Intellectual Disability; | 1959 |
Tryptophan loading and excretion of 5-hydroxyindoleacetic acid in normal and schizophrenic subjects.
Topics: Biological Transport; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Schizophrenia; Tryptopha | 1959 |
[Effect of aminazine therapy on the serotonin in the blood and the excretion of 5-hydroxyindolacetic acid in the urine of patients with schizophrenia].
Topics: Chlorpromazine; Hydroxyindoleacetic Acid; Indoleacetic Acids; Schizophrenia; Serotonin | 1962 |
[URINARY ELIMINATION OF 5-HYDROXYINDOLACETIC ACID, HOMOVANILLIC AND VANILLYLMANDELIC ACIDS IN SCHIZOPHRENIC SUBJECTS WITH RESERPINE AND CHLORPROMAZINE].
Topics: Benzaldehydes; Chlorpromazine; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Mandelic Acids; | 1963 |
[STUDIES ON URINARY EXCRETION OF 5-HYDROXYINDOLEACETIC ACID].
Topics: Asian People; Child; China; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Korea; Metabolism; | 1963 |
[ELIMINATION OF THE PRINCIPAL URINARY METABOLITES OF SEROTONIN, DOPAMINE, NORADRENALINE, AND ADRENALINE DURING TREATMENT WITH RESERPINE AND WITH CHLOROPROMAZINE IN SCHIZOPHRENIC SUBJECTS. CLINICO-BIOLOGICAL CORRELATIONS].
Topics: Benzaldehydes; Chlorpromazine; Dopamine; Epinephrine; Hydroxyindoleacetic Acid; Indoleacetic Acids; | 1963 |
RESERPINE TOLERANCE TEST IN SCHIZOPHRENIC SUBJECTS.
Topics: Adolescent; Blood Platelets; Drug Therapy; Drug Tolerance; Humans; Hydroxyindoleacetic Acid; Pharmac | 1964 |
[SEROTONIN AND PSYCHIATRY].
Topics: Bipolar Disorder; Catecholamines; Drug Therapy; Hallucinations; Hallucinogens; Humans; Hydroxyindole | 1964 |
URINARY METABOLITES OF SOME MONOAMINES AND CLINICAL EFFECTS UNDER RESERPINE AND CHLORPROMAZINE.
Topics: Autonomic Nervous System Diseases; Chlorpromazine; Drug Therapy; Extrapyramidal Tracts; Fluids and S | 1965 |
[Urinary excretion of 5-HIAA in normal Chinese and schizophrenic subjects. II. Urinary output of 5-HIAA among schizophrenic patients].
Topics: Asian People; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Schizophrenia | 1962 |
[Urinary excretion of 5-HIAA in normal Chinese and schizophrenic subjects. III. T.L.T. in presence of tranquilizers for chronic schizophrenics].
Topics: Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Schizophrenia; Tranquilizing Agents | 1962 |
Effects of acute metabolic stress on the peripheral vasopressinergic system in schizophrenia.
Topics: Adrenocorticotropic Hormone; Adult; Behavior; Female; Homovanillic Acid; Humans; Hydrocortisone; Hyd | 2003 |
Monoaminergic dysregulation in glutathione-deficient mice: possible relevance to schizophrenia?
Topics: Amphetamine; Animals; Brain; Chromatography, High Pressure Liquid; Dopamine; Glutathione; Hallucinog | 2005 |
HPLC determination of serotonin and its metabolites from human platelet-rich plasma; shift to 5-hydroxytryptophol formation following alcohol consumption.
Topics: 5-Hydroxytryptophan; Adult; Alcohol Drinking; Chromatography, High Pressure Liquid; Female; Humans; | 2008 |
[Tryptaminuria and urinary 5-H.I.A.A. in neuropsychiatry (preliminary note)].
Topics: Bipolar Disorder; Depression; Humans; Hydroxyindoleacetic Acid; Monoamine Oxidase Inhibitors; Neurot | 1967 |
[The probenecid test and its application to research in schizophrenia].
Topics: Biogenic Amines; Brain; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methoxyhydroxyphenylgly | 1984 |
[Changes in the CSF levels of monoamine metabolites in 102 chronic schizophrenic patients following probenecid before and after neuroleptic medication].
Topics: Adult; Antipsychotic Agents; Biogenic Amines; Chronic Disease; Female; Homovanillic Acid; Humans; Hy | 1984 |
Urinary acid metabolites of biogenic amines in schizophrenic patients.
Topics: Biogenic Amines; Blood Platelets; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Indoleacetic | 1980 |
CSF monoamine metabolites in child and adult psychiatric patients. A developmental perspective.
Topics: Adolescent; Adult; Age Factors; Aged; Autistic Disorder; Bipolar Disorder; Child; Child, Preschool; | 1980 |
Aberrant monoamine metabolite levels in CSF and family history of schizophrenia. Their relationships in schizophrenic patients.
Topics: Adolescent; Adult; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Metho | 1980 |
Concentrations of monoamine metabolites and chlorpromazine in cerebrospinal fluid for prediction of therapeutic response in psychotic patients treated with neuroleptic drugs.
Topics: Antipsychotic Agents; Chlorpromazine; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; | 1980 |
Noradrenergic overactivity in chronic schizophrenia: evidence based on cerebrospinal fluid noradrenaline and cyclic nucleotide concentrations.
Topics: Adult; Chronic Disease; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Ag | 1980 |
Relationship between estimated premorbid adjustment and CSF homovanillic acid and 5-hydroxyindoleacetic acid levels.
Topics: Adolescent; Adult; Affective Disorders, Psychotic; Aged; Female; Homovanillic Acid; Humans; Hydroxyi | 1981 |
[Catecholamine and indoleamine metabolism in groups of patients with paranoid and simple forms of schizophrenia].
Topics: Adult; Biogenic Amines; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Mal | 1981 |
[Changes in the levels of adrenergic and serotoninergic indices in patients with depressive states].
Topics: Adolescent; Adult; Biogenic Amines; Depression; Dihydroxyphenylalanine; Dopamine; Epinephrine; Homov | 1981 |
Effects of short- and long-term neuroleptic treatment on brain serotonin synthesis and turnover: focus on the serotonin hypothesis of schizophrenia.
Topics: Animals; Antipsychotic Agents; Brain; Chlorpromazine; Haloperidol; Humans; Hydroxyindoleacetic Acid; | 1981 |
Serotonin metabolite concentrations in cerebrospinal fluid from schizophrenic patients -- relationships to family history.
Topics: Female; Humans; Hydroxyindoleacetic Acid; Male; Reference Values; Schizophrenia; Serotonin; Sex Fact | 1981 |
Biological quantitative methods in the evaluation of psychiatric treatment: some biochemical criteria.
Topics: Antidepressive Agents, Tricyclic; Antipsychotic Agents; Catechol O-Methyltransferase; Electroconvuls | 1982 |
[Various indices of biogenic monoamine metabolism in schizophrenic patients during treatment with atropine comas].
Topics: Adult; Atropine; Biogenic Amines; Convulsive Therapy; Epinephrine; Humans; Hydroxyindoleacetic Acid; | 1982 |
Low CSF 5-hydroxyindoleacetic acid in schizophrenic patients with enlarged cerebral ventricles.
Topics: Adult; Chronic Disease; Female; Humans; Hydrocephalus; Hydroxyindoleacetic Acid; Male; Nervous Syste | 1983 |
Reduced lumbar CSF somatostatin levels in Alzheimer's disease.
Topics: Aged; Alcohol Amnestic Disorder; Alzheimer Disease; Dementia; Female; Homovanillic Acid; Humans; Hyd | 1982 |
REM sleep eye movement activity and CSF concentrations of 5-hydroxyindoleacetic acid in psychiatric patients.
Topics: Adult; Depressive Disorder; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Probenecid; Psychot | 1983 |
Relationship between cerebrospinal fluid amine metabolites, neuroendocrine findings and personality dimensions (Marke-Nyman scale factors) in psychiatric patients.
Topics: Alcoholism; Bipolar Disorder; Depressive Disorder; Dexamethasone; Female; Homovanillic Acid; Humans; | 1983 |
Amine metabolites and neuroendocrine responses related to depression and suicide.
Topics: Alcoholism; Depression; Depressive Disorder; Dexamethasone; Female; Homovanillic Acid; Humans; Hydro | 1983 |
The effect of dexamethasone on cerebrospinal fluid monoamine metabolites and cortisol in psychiatric patients.
Topics: Adult; Aged; Alcoholism; Bipolar Disorder; Depressive Disorder; Dexamethasone; Female; Homovanillic | 1983 |
Gamma-hydroxybutyrate in the treatment of schizophrenia.
Topics: Adult; Double-Blind Method; Homovanillic Acid; Humans; Hydroxybutyrates; Hydroxyindoleacetic Acid; M | 1983 |
Concentrations of 5-hydroxyindoleacetic acid and homovanillic acid in the cerebrospinal fluid of chronic therapy-resistant schizophrenics before and after hemodialysis therapy.
Topics: Adult; Chromatography, High Pressure Liquid; Double-Blind Method; Female; Homovanillic Acid; Humans; | 1983 |
CSF 5-HIAA and suicide in non-depressed schizophrenics.
Topics: Adult; Humans; Hydroxyindoleacetic Acid; Middle Aged; Schizophrenia; Schizophrenic Psychology; Suici | 1983 |
Smooth pursuit eye movements, clinical symptoms, CSF metabolites, and skin conductance habituation in schizophrenic patients.
Topics: Adult; Antipsychotic Agents; Chronic Disease; Eye Movements; Female; Galvanic Skin Response; Habitua | 1983 |
Cerebrospinal fluid biochemical examinations: do they reflect clinical or biological differences?
Topics: Adult; Aged; Alcoholism; Bipolar Disorder; Calcium; Depressive Disorder; Dexamethasone; Female; Homo | 1983 |
Cerebroventricular size and cerebrospinal fluid monoamine metabolites in schizophrenic patients and healthy volunteers.
Topics: Adult; Age Factors; Cerebral Ventriculography; Female; Homovanillic Acid; Humans; Hydroxyindoleaceti | 1983 |
Reliability of norepinephrine and major monoamine metabolite measurements in CSF of schizophrenic patients.
Topics: Adult; Chronic Disease; Female; Glycols; Homovanillic Acid; Hospitalization; Humans; Hydroxyindoleac | 1983 |
Measurement of 3-methoxy-4-hydroxyphenylacetic acid (HVA) in plasma by high-performance liquid chromatography with electrochemical detector (HPLC-EC).
Topics: Animals; Antipsychotic Agents; Chromatography, High Pressure Liquid; Electrochemistry; Female; Homov | 1983 |
Time course for effects of sulpiride and chlorpromazine on monoamine metabolite and prolactin levels in cerebrospinal fluid from schizophrenic patients.
Topics: Adolescent; Adult; Cerebrospinal Fluid Proteins; Chlorpromazine; Dopamine Antagonists; Female; Homov | 1984 |
CSF 5-hydroxyindoleacetic acid levels in suicidal schizophrenic patients.
Topics: Adult; Aggression; Female; Humans; Hydroxyindoleacetic Acid; Male; Mental Disorders; Schizophrenia; | 1984 |
Elevated cerebrospinal fluid noradrenaline in tardive dyskinesia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Antipsychotic Agents; Dyskinesia, Drug-Induced; Homovan | 1984 |
Effect of propranolol on monoamine metabolites in cerebrospinal fluid of patients with chronic schizophrenia.
Topics: Adult; Chromatography, High Pressure Liquid; Double-Blind Method; Drug Evaluation; Female; Homovanil | 1984 |
Bilateral skin conductance activity, clinical symptoms and CSF monoamine metabolite levels in unmedicated schizophrenics, differing in rate of habituation.
Topics: Adult; Biogenic Amines; Female; Galvanic Skin Response; Habituation, Psychophysiologic; Homovanillic | 1984 |
Seasonal variations of human lumbar CSF neurotransmitter metabolite concentrations.
Topics: Adult; Alzheimer Disease; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxy | 1984 |
CSF neurochemistry in depressed, manic, and schizophrenic patients compared with that of normal controls.
Topics: Adolescent; Adult; Age Factors; Aged; Bipolar Disorder; Calcium; Choline; Depressive Disorder; Femal | 1984 |
CSF monoamine metabolites in depression and schizophrenia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Depression; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Mal | 1980 |
An association between low levels of 5-HIAA and HVA in cerebrospinal fluid and early mortality in a diagnostically mixed psychiatric sample.
Topics: Adult; Aged; Cause of Death; Depressive Disorder; Follow-Up Studies; Homovanillic Acid; Hospital Rec | 1993 |
Postmortem stability of monoamines, their metabolites, and receptor binding in rat brain regions.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Brain; Brain Chemistry; Dopamine; Huma | 1994 |
Noradrenergic activity and prediction of psychotic relapse following haloperidol withdrawal in schizophrenia.
Topics: Adult; Chromogranin A; Chromogranins; Haloperidol; Homovanillic Acid; Humans; Hydroxyindoleacetic Ac | 1994 |
Neuropsychological correlates of central monoamine function in chronic schizophrenia: relationship between CSF metabolites and cognitive function.
Topics: Adult; Cerebral Cortex; Cognition Disorders; Discrimination Learning; Dopamine; Homovanillic Acid; H | 1994 |
Effectiveness of concomitant setiptiline maleate (Tecipul) on negative symptoms of schizophrenia.
Topics: Adult; Biogenic Monoamines; Chronic Disease; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic | 1994 |
CSF concentrations of neurotensin in schizophrenia: an investigation of clinical and biochemical correlates.
Topics: Adult; Female; Haloperidol; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydrox | 1994 |
Effects of risperidone on phencyclidine-induced behaviors: comparison with haloperidol and ritanserin.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Chromatography, High Pressure Liquid; | 1994 |
Clozapine therapy and increases in homovanillic acid.
Topics: Chromatography, High Pressure Liquid; Clozapine; Dopamine; Homovanillic Acid; Humans; Hydroxyindolea | 1995 |
Behavioral vs biochemical prediction of clinical stability following haloperidol withdrawal in schizophrenia.
Topics: Adult; Age of Onset; Haloperidol; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Logistic Mode | 1995 |
CSF 5-HIAA and atmospheric pressure: failure to replicate.
Topics: Atmospheric Pressure; Body Height; Depressive Disorder; Homovanillic Acid; Humans; Hydroxyindoleacet | 1993 |
Effect of neuroleptic medication on cerebrospinal fluid monoamine metabolite concentrations in schizophrenia. Serotonin-dopamine interactions as a target for treatment.
Topics: Adult; Dopamine; Haloperidol; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Psychiatric | 1993 |
Monoamine neurotransmitter interactions in drug-free and neuroleptic-treated schizophrenics.
Topics: Adult; Antipsychotic Agents; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Meth | 1993 |
Are monoamine metabolites in cerebrospinal fluid worth measuring?
Topics: Animals; Brain; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Mental Disorders; Met | 1993 |
Low cerebrospinal fluid homovanillic acid-5-hydroxyindoleacetic acid ratio predicts clozapine efficacy: a replication.
Topics: Clozapine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Prospective Studies; Psychiatric Sta | 1993 |
Serotonin, suicide and schizophrenia.
Topics: Follow-Up Studies; Humans; Hydroxyindoleacetic Acid; Risk Factors; Schizophrenia; Schizophrenic Psyc | 1993 |
Serotonin in violent patients with schizophrenia.
Topics: Adult; Brain; Female; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Psychiatric Status Rating | 1995 |
The relationship between urine excretion and biogenic amines and their metabolites in cerebrospinal fluid of schizophrenic patients.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Biogenic Amines; Chronic Disease; Drinking; Female; Histamine | 1996 |
Exaggerated responsivity of brain dopaminergic system activity in schizophrenia: a preliminary finding of increased variance of plasma homovanillic acid level in a chronic patient.
Topics: Adult; Brain; Chronic Disease; Dopamine; Female; Homovanillic Acid; Humans; Hydrocortisone; Hydroxyi | 1996 |
Effects of antidepressants on phencyclidine-induced enhancement of immobility in a forced swimming test in mice.
Topics: Animals; Antidepressive Agents; Depression; Desipramine; Hallucinogens; Hydroxyindoleacetic Acid; Ma | 1997 |
Failure to replicate an association between a rare allele of a tyrosine hydroxylase gene microsatellite and schizophrenia.
Topics: Alleles; Gene Expression Regulation, Enzymologic; Gene Frequency; Homovanillic Acid; Humans; Hydroxy | 1998 |
Neurochemical variables in schizophrenic patients during switching from neuroleptics to clozapine.
Topics: Adolescent; Adult; Antipsychotic Agents; Chlorpromazine; Clozapine; Homovanillic Acid; Humans; Hydro | 1998 |
CSF levels of HVA and 5-HIAA in drug-free schizophrenic patients and healthy controls: a prospective study focused on their predictive value for outcome in schizophrenia.
Topics: Adolescent; Adult; Antipsychotic Agents; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid | 1998 |
Season of birth variations in dimensions of functioning evaluated by the diagnostic interview for borderline patients.
Topics: Anxiety Disorders; Biogenic Monoamines; Birth Certificates; Borderline Personality Disorder; Homovan | 2000 |
Differential involvement of dopamine in the shell and core of the nucleus accumbens in the expression of latent inhibition to an aversively conditioned stimulus.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Avoidance Learning; Behavior, Animal; Conditioning, Psychol | 2000 |
Relationships between interleukins, neurotransmitters and psychopathology in drug-free male schizophrenics.
Topics: Adult; Antipsychotic Agents; Dopamine; Enzyme-Linked Immunosorbent Assay; Haloperidol; Homovanillic | 2000 |
Transmitter precursors and metabolites in human ventricular cerebrospinal fluid.
Topics: Cerebral Ventricles; Frontal Lobe; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Neurotic Dis | 1976 |
Cerebrospinal fluid monoamine metabolites and cyclic nucleotides in chronic schizophrenic patients with tardive dyskinesia or drug-induced tremor.
Topics: Adult; Chronic Disease; Cyclic AMP; Cyclic GMP; Cyproheptadine; Dyskinesia, Drug-Induced; Female; Ho | 1979 |
Monoamine mechanisms in chronic schizophrenia: post-mortem neurochemical findings.
Topics: Aged; Brain Chemistry; Catechol O-Methyltransferase; Chronic Disease; Dopamine; Dopamine beta-Hydrox | 1979 |
Relationships between clinical and biochemical effects of melperone and thiothixene in psychotic women.
Topics: Butyrophenones; Diazepam; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methoxyhydrox | 1979 |
Levels of HIAA and VMA in C.S.F. of schizophrenics before and after treatment.
Topics: Catecholamines; Electroconvulsive Therapy; Female; Humans; Hydroxyindoleacetic Acid; Male; Phenothia | 1978 |
Brain tryptophan metabolism in schizophrenia: a post mortem study of metabolites of the serotonin and kynurenine pathways in schizophrenic and control subjects.
Topics: Aged; Aging; Brain; Female; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; Middle Aged; Myocard | 1979 |
Reduction of MOPEG levels in cerebrospinal fluid of psychotic women after electroconvulsive treatment.
Topics: Biogenic Amines; Electroconvulsive Therapy; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindol | 1979 |
[Excretion of catecholamines and tryptophan derivatives in schizophrenia].
Topics: Adolescent; Adult; Biogenic Amines; Dihydroxyphenylalanine; Dopamine; Epinephrine; Female; Humans; H | 1976 |
Interactions between central monoaminergic systems: dopamine-serotonin.
Topics: Adolescent; Adult; Aged; Bipolar Disorder; Depression; Dopamine; Dyskinesia, Drug-Induced; Female; H | 1979 |
Cerebrospinal fluid cyclic AMP and acid monoamine metabolites following probenecid: studies in psychiatric patients.
Topics: Adolescent; Adult; Aged; Biogenic Amines; Chlorpromazine; Cyclic AMP; Depression; Female; Homovanill | 1979 |
Dopamine, noradrenaline and serotonin spinal fluid metabolites in temporal lobe epileptic patients with schizophrenic symptomatology.
Topics: Adolescent; Adult; Child; Dopamine; Epilepsy, Temporal Lobe; Homovanillic Acid; Humans; Hydroxyindol | 1979 |
Monoamine metabolite levels in cerebrospinal fluid and brain atrophy in lobotomized schizophrenic patients.
Topics: Atrophy; Brain Diseases; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; | 1979 |
Monoamines and monoamine metabolites in brains from demented schizophrenics.
Topics: Brain; Brain Chemistry; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; | 1979 |
Long-term amphetamine treatment decreases brain serotonin metabolism: implications for theories of schizophrenia.
Topics: Animals; Behavior, Animal; Brain; Brain Chemistry; Cats; Dextroamphetamine; Disease Models, Animal; | 1979 |
Lithium: clinical effects and cerebrospinal fluid acid monoamine metabolites.
Topics: Adult; Affective Symptoms; Aged; Biogenic Amines; Bipolar Disorder; Depression; Electroencephalograp | 1977 |
MAO activity, csf amine metabolites, and drug-free improvement in schizophrenia.
Topics: Adolescent; Adult; Blood Platelets; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Mal | 1978 |
Comparative simultaneous measurement of cerebrospinal fluid 5-hydroxyindoleacetic acid and blood serotonin levels in delirium tremens and clozapine-induced delirious reaction.
Topics: Adult; Alcohol Withdrawal Delirium; Clozapine; Delirium; Dibenzazepines; Female; Humans; Hydroxyindo | 1978 |
CSF acid monoamine metabolites in psychotic syndromes: what might they signify?
Topics: Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Phenylacetates; Prognosis; Psychotic Disorders; | 1978 |
Effect of baclofen on cerebrospinal-fluid levels of 5-hydroxyindoleacetic acid and homovanillic acid.
Topics: Adult; Aminobutyrates; Baclofen; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; | 1977 |
CSF amine metabolites, clinical symptoms, and body movement in psychiatric patients.
Topics: Adult; Anger; Anxiety; Arousal; Brain; Depression; Female; Homovanillic Acid; Humans; Hydroxyindolea | 1976 |
CSF acid monoamine metabolities as a possible reflection of central MAO activity in chronic schizophrenia.
Topics: Acute Disease; Adolescent; Adult; Bipolar Disorder; Chronic Disease; Female; Homovanillic Acid; Huma | 1976 |
Clinical and biochemical parameters during neuroleptic treatment. I. Investigations with haloperidol.
Topics: Adult; Female; Hallucinations; Haloperidol; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Mal | 1976 |
Precursors and metabolites of 5-hydroxytryptamine and dopamine in the ventricular cerebrospinal fluid of psychiatric patients.
Topics: Adult; Aged; Anxiety Disorders; Brain Diseases; Cerebral Ventricles; Depression; Female; Homovanilli | 1976 |
[Differences in serotonin and dopamine metabolism in psychopathy and sluggish schizophrenia].
Topics: Adult; Antisocial Personality Disorder; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Aci | 1976 |
Urinary excretion of n,n-dimethylated tryptamines in chronic schizophrenia. A review of the present status of the hypothesis.
Topics: 5-Methoxytryptamine; Adult; Bufotenin; Chronic Disease; Epinephrine; Female; Humans; Hydroxyindoleac | 1976 |
Thioridazine: central dopamine turnover and clinical effects of antipsychotic drugs.
Topics: Adolescent; Adult; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Midd | 1975 |
Role of biogenic amines in certain pathological conditions.
Topics: Acute Disease; Adult; Aggression; Biogenic Amines; Bipolar Disorder; Chlorpromazine; Chronic Disease | 1975 |
Cerebrospinal fluid amine metabolites in acute schizophrenia.
Topics: Acute Disease; Adolescent; Adult; Amines; Bipolar Disorder; Dopamine; Homovanillic Acid; Humans; Hyd | 1975 |
Central noradrenergic function in man: vanillylmandelic acid in CSF.
Topics: Acute Disease; Affective Symptoms; Bipolar Disorder; Depression; Homovanillic Acid; Humans; Hydroxyi | 1975 |
Cerebrospinal fluid amine metabolites in affective illness and schizophrenia: clinical and pharmacological studies.
Topics: Affective Symptoms; Amines; Depression; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Imipram | 1975 |
Electrodermal orienting response and central nervous system dopamine and serotonin activity in schizophrenia.
Topics: Acoustic Stimulation; Acute Disease; Adolescent; Adult; Brain; Dopamine; Galvanic Skin Response; Hom | 1992 |
5-Hydroxyindoleacetic acid in cerebrospinal fluid and prediction of suicidal behaviour in schizophrenia.
Topics: Female; Humans; Hydroxyindoleacetic Acid; Male; Predictive Value of Tests; Prospective Studies; Schi | 1992 |
Biogenic amine metabolites in plasma of drug-naive schizophrenic patients: associations with symptomatology.
Topics: Adult; Arousal; Chromatography, High Pressure Liquid; Homovanillic Acid; Hospitalization; Humans; Hy | 1992 |
Norepinephrine in acute exacerbations of chronic schizophrenia. Negative symptoms revisited.
Topics: Acute Disease; Adult; Haloperidol; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methox | 1990 |
Neuroleptic malignant syndrome: a study of CSF monoamine metabolism.
Topics: Adult; Biogenic Monoamines; Bipolar Disorder; Depressive Disorder; Female; Homovanillic Acid; Humans | 1990 |
Concentration gradients for HVA, 5-HIAA, ascorbic acid, and uric acid in cerebrospinal fluid.
Topics: Adult; Aged; Alcohol Amnestic Disorder; Ascorbic Acid; Brain; Dementia; Female; Homovanillic Acid; H | 1990 |
CSF 5-hydroxyindoleacetic acid levels and suicide attempts in schizophrenia.
Topics: Adult; Chronic Disease; Female; Humans; Hydroxyindoleacetic Acid; Male; Psychotic Disorders; Schizop | 1990 |
Cerebrospinal fluid and plasma monoamine metabolites and their relation to psychosis. Implications for regional brain dysfunction in schizophrenia.
Topics: Adult; Brain; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhyd | 1990 |
Effects of mianserin on negative symptoms in schizophrenia.
Topics: Adult; Antiparkinson Agents; Antipsychotic Agents; Brain; Chronic Disease; Drug Therapy, Combination | 1990 |
5-HIAA in cerebrospinal fluid and deficit schizophrenic characteristics.
Topics: Adult; Cognition; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Psychiatric Status Rating Sca | 1990 |
Relationship between abnormal brainstem auditory-evoked potentials and subnormal CSF levels of HVA and 5-HIAA in first-episode schizophrenic patients.
Topics: Adult; Brain Stem; Evoked Potentials, Auditory, Brain Stem; Female; Homovanillic Acid; Humans; Hydro | 1990 |
Intercorrelations among monoamine metabolite concentrations in human lumbar CSF are not due to a shared acid transport system.
Topics: Acid-Base Equilibrium; Administration, Oral; Blood-Brain Barrier; Depressive Disorder; Dose-Response | 1990 |
Evidence for the role of serotonin in the regulation of slow wave sleep in schizophrenia.
Topics: Adult; Dopamine; Hospitalization; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Schizophrenia | 1991 |
Lateral ventricle-brain ratio and balance between CSF HVA and 5-HIAA in schizophrenia.
Topics: Adult; Age Factors; Bipolar Disorder; Body Height; Body Weight; Brain; Brain Chemistry; Cerebral Ven | 1991 |
Regional brain glucose metabolism: correlations to biochemical measures and anxiety in patients with schizophrenia.
Topics: Adult; Anxiety; Arousal; Blood Glucose; Brain; Brain Mapping; Dominance, Cerebral; Energy Metabolism | 1991 |
CSF chromogranin A-like immunoreactivity in schizophrenia. Assessment of clinical and biochemical relationships.
Topics: Adult; Arousal; Atrophy; Brain; Chromogranin A; Chromogranins; Haloperidol; Homovanillic Acid; Human | 1991 |
Serotonin and schizophrenia: correlations between serotonergic activity and schizophrenic motor behavior.
Topics: Adult; Blood Platelets; Humans; Hydroxyindoleacetic Acid; Motor Activity; Psychiatric Status Rating | 1985 |
Low HVA and normal 5HIAA CSF levels in drug-free schizophrenic patients compared to healthy volunteers: correlations to symptomatology and family history.
Topics: Adult; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Phenylacetates; | 1985 |
CSF monoamine metabolites in chronic schizophrenic patients who attempt suicide.
Topics: Adult; Chronic Disease; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; | 1985 |
Anterior cerebellar vermal stimulation: effect on behavior and basal forebrain neurochemistry in rat.
Topics: 5-Hydroxytryptophan; Animals; Brain Mapping; Cerebellum; Dopamine; Electric Stimulation; Humans; Hyd | 1985 |
Plasma amino acids in relation to cerebrospinal fluid monoamine metabolites in schizophrenic patients and healthy controls.
Topics: Adult; Amino Acids; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydrox | 1985 |
Brain ventricular size and CSF monoamine metabolites in an adolescent inpatient population.
Topics: Adolescent; Adult; Age Factors; Cerebral Ventricles; Child; Dilatation, Pathologic; Female; Homovani | 1985 |
[Monoamine metabolite levels in cerebrospinal fluid of schizophrenic patients].
Topics: Adolescent; Adult; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; S | 1985 |
Biological studies of schizophrenia in Europe.
Topics: Brain; Brain Chemistry; Dopamine; Endorphins; Environment; Europe; Genetic Markers; HLA Antigens; Hu | 1986 |
Serotonin and 5-hydroxyindoleacetic acid in brains of suicide victims. Comparison in chronic schizophrenic patients with suicide as cause of death.
Topics: Adolescent; Adult; Aged; Animals; Basal Ganglia; Brain Chemistry; Chronic Disease; Coroners and Medi | 1986 |
Correlates of lateral ventricular size in chronic schizophrenia, II: biological measures.
Topics: Adult; Apomorphine; Brain; Cerebral Ventricles; Chronic Disease; Growth Hormone; Homovanillic Acid; | 1986 |
Neurochemical findings in the cerebrospinal fluid of schizophrenic patients with tardive dyskinesia and neuroleptic-induced parkinsonism.
Topics: Adult; Aged; Antipsychotic Agents; Catecholamines; Dopamine; Dyskinesia, Drug-Induced; Epinephrine; | 1986 |
CSF levels of receptor-active endorphins in schizophrenic patients: correlations with symptomatology and monoamine metabolites.
Topics: Adolescent; Adult; Antipsychotic Agents; Endorphins; Female; Homovanillic Acid; Humans; Hydroxyindol | 1986 |
(Auto)aggression and CSF 5-HIAA in depression and schizophrenia.
Topics: Aggression; Depressive Disorder; Humans; Hydroxyindoleacetic Acid; Risk; Schizophrenia; Schizophreni | 1986 |
Serotonergic function and suicidal behavior in personality disorders.
Topics: Brain; Depressive Disorder; Humans; Hydroxyindoleacetic Acid; Personality Disorders; Risk; Schizophr | 1986 |
Cerebrospinal fluid correlates of suicide attempts and aggression.
Topics: Aggression; Animals; Bipolar Disorder; Depressive Disorder; Homovanillic Acid; Humans; Hydroxyindole | 1986 |
Suicide and aggression in schizophrenia. Neurobiologic correlates.
Topics: Aggression; Brain; Cerebral Ventricles; Dexamethasone; Homovanillic Acid; Humans; Hydrocortisone; Hy | 1986 |
Monoamines and their metabolites in cerebrospinal fluid of patients with senile dementia of Alzheimer type using high performance liquid chromatography and gas chromatography-mass spectrometry.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biogenic Amines; Chromatography, High Pressure Liquid; G | 1987 |
Preliminary evidence of reduced combined output of dopamine and its metabolites in chronic schizophrenia.
Topics: Adult; Chronic Disease; Circadian Rhythm; Dopamine; Female; Haloperidol; Hospitalization; Humans; Hy | 1987 |
Relationship between tryptophan and serotonin concentrations in postmortem human brain.
Topics: Brain; Humans; Hydroxyindoleacetic Acid; Indoles; Schizophrenia; Serotonin; Suicide; Tryptophan | 1987 |
CSF creatinine in schizophrenia.
Topics: Adult; Blood-Brain Barrier; Creatinine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; | 1988 |
N-acetylation and serotonergic measures in a group of psychiatric patients.
Topics: Acetylation; Adult; Bipolar Disorder; Depressive Disorder; Female; Humans; Hydroxyindoleacetic Acid; | 1988 |
The effect of electroconvulsive therapy on CSF amine metabolites in schizophrenic patients.
Topics: Adult; Aged; Electroconvulsive Therapy; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleace | 1988 |
Seasonal changes of CSF monoamine metabolites in psychiatric patients: what is the source?
Topics: Bipolar Disorder; Depressive Disorder; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Mental D | 1988 |
Corrections to a 1980 article on CSF monoamine metabolites.
Topics: 3,4-Dihydroxyphenylacetic Acid; Depressive Disorder; Homovanillic Acid; Humans; Hydroxyindoleacetic | 1989 |
[Suicidal behavior of schizophrenic patients. Biochemical and morphologic findings].
Topics: Brain; Humans; Hydroxyindoleacetic Acid; Schizophrenia; Schizophrenic Psychology; Serotonin; Suicide | 1988 |
CSF neurochemical study of tardive dyskinesia.
Topics: Acetylcholinesterase; Dyskinesia, Drug-Induced; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; | 1989 |
CSF norepinephrine in schizophrenia is elevated prior to relapse after haloperidol withdrawal.
Topics: Adult; Chromatography, High Pressure Liquid; Chronic Disease; Haloperidol; Homovanillic Acid; Humans | 1989 |
Clozapine pharmacology and tardive dyskinesia.
Topics: Adolescent; Adult; Clozapine; Dibenzazepines; Dyskinesia, Drug-Induced; Epinephrine; Female; Homovan | 1989 |
Biochemical markers for suicidal behavior.
Topics: Dexamethasone; Female; Humans; Hydrocortisone; Hydroxyindoleacetic Acid; Magnesium; Schizophrenia; S | 1985 |
Cerebrospinal fluid magnesium and calcium related to amine metabolites, diagnosis, and suicide attempts.
Topics: Adjustment Disorders; Adult; Aged; Calcium; Depressive Disorder; Dexamethasone; Female; Homovanillic | 1985 |
Atrophy limited to the third ventricle in chronic schizophrenic patients. Report of a controlled series.
Topics: Adult; Atrophy; Brain; Cerebellum; Cerebral Cortex; Cerebral Ventricles; Female; Homovanillic Acid; | 1985 |
Decrease in dopamine, its metabolites and noradrenaline in cerebrospinal fluid of schizophrenic patients after withdrawal of long-term neuroleptic treatment.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Antipsychotic Agents; Chronic Disease; Dopamine; Female; Halo | 1985 |
Further studies on the mechanism of antipsychotic action: potentiation by alpha-methyltyrosine of thioridazine effects in chronic schizophrenics.
Topics: Chronic Disease; Drug Synergism; Evaluation Studies as Topic; Female; Homovanillic Acid; Humans; Hyd | 1973 |
5-hydroxyindole compounds in the cerebrospinal fluid of patients with psychiatric or neurological diseases.
Topics: Alcoholism; Bipolar Disorder; Central Nervous System Diseases; Humans; Hydroxyindoleacetic Acid; Imi | 1966 |
Use of cerebrospinal fluid drawn at pneumoencephalography in the study of monoamine metabolism in man.
Topics: Adolescent; Adult; Brain Diseases; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Homovani | 1974 |
Effects of -methyltyrosine on the cerebrospinal fluid content of HVA and 5-HIAA in man.
Topics: Cerebrospinal Fluid; Depression; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Methyltyrosin | 1971 |
Steady-state levels of probenecid and their relation to acid monoamine metabolites in human cerebrospinal fluid.
Topics: Adult; Aged; Benzoates; Bipolar Disorder; Blood-Brain Barrier; Female; Humans; Huntington Disease; H | 1972 |
Concentration of homovanillic acid and 5-hydroxyindoleacetic acid in the cerebrospinal fluid after treatment with probenecid in patients with drug-induced tardive dyskinesia.
Topics: Dopamine; Humans; Hydroxyindoleacetic Acid; Movement Disorders; Phenylacetates; Probenecid; Schizoph | 1970 |
Effect of thioproperazine on 5-HIAA content in urine and cerebrospinal fluid of chronic schizophrenic patients.
Topics: Adult; Chronic Disease; Female; Humans; Hydroxyindoleacetic Acid; Middle Aged; Phenothiazines; Psych | 1970 |
[Effects of thioproperazine on the urinary excretion and concentration in the cerebrospinal fluid of 5-hydroxyindoleacetic acid in chronic schizophrenia].
Topics: Chronic Disease; Female; Humans; Hydroxyindoleacetic Acid; Middle Aged; Phenothiazines; Schizophreni | 1971 |
[Effect of clozapine on the excretion of 3-methoxy-4-hydroxy-phenylglycol, homovanillic acid and 5-hydroxy-indole acetic acid in urine and cerebrospinal fluid].
Topics: Azepines; Bipolar Disorder; Dopamine beta-Hydroxylase; Glycols; Homovanillic Acid; Humans; Hydroxyin | 1974 |
[The effect of reserpine on serotonin metabolism in patients with schizophrenia and reactive conditions].
Topics: Adjustment Disorders; Adult; Autonomic Nervous System; Blood Pressure; Blushing; Gastrointestinal Mo | 1974 |
Fluorometric measurement of 5-hydroxyindoleacetic acid (5HIAA) and tryptophan in human CSF: effects of high doses of probenecid.
Topics: Administration, Oral; Adolescent; Adult; Bipolar Disorder; Brain Chemistry; Depression; Female; Fluo | 1974 |
Simultaneous quantification of homovanillic acid and 5-hydroxyindoleacetic acid in cerebrospinal fluid by mass fragmentography.
Topics: Gas Chromatography-Mass Spectrometry; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Schizophr | 1974 |
Cerebrospinal fluid levels of MHPG in affective disorders.
Topics: Adjustment Disorders; Affective Symptoms; Bipolar Disorder; Carbonates; Catechols; Depression; Glyco | 1972 |
Relationship of dietary tryptophan and niacin to tryptophan metabolism in schizophrenics and nonschizophrenics.
Topics: Acetates; Aminohippuric Acids; Diet; Female; Humans; Hydroxyindoleacetic Acid; Indican; Indoles; Kyn | 1974 |
Central dopamine turnover in schizophrenic syndromes.
Topics: Affective Symptoms; Chlorpromazine; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic | 1974 |
Antipsychotic efficacy of clozapine in correlation to changes in catecholamine metabolism in man.
Topics: Bipolar Disorder; Carbon Radioisotopes; Catecholamines; Chromatography, Gas; Dibenzazepines; Dopamin | 1974 |
Clinical measurements of central dopamine and 5-hydroxytryptamine metabolism: reliability and interpretation of cerebrospinal fluid acid monoamine metabolite measures.
Topics: Age Factors; Central Nervous System; Chemistry, Clinical; Dopamine; Fluorometry; Humans; Hydroxyindo | 1972 |
Amines and aphrodisiacs in chronic schizophrenia.
Topics: Adult; Aphrodisiacs; Epinephrine; Evaluation Studies as Topic; Female; Humans; Hydroxyindoleacetic A | 1972 |
Acid monoamine metabolites in human cerebrospinal fluid and their relations to age and sex.
Topics: Adolescent; Adult; Age Factors; Aged; Chronic Disease; Female; Humans; Hydroxyindoleacetic Acid; Mal | 1971 |
Clinical and pharmacological effects of monoamine precursors or haloperidol in chronic schizophrenia.
Topics: 5-Hydroxytryptophan; Dihydroxyphenylalanine; Haloperidol; Humans; Hydroxyindoleacetic Acid; Phenylac | 1968 |
Deficient transport mechanism for the removal of acid monoamine metabolites from cerebrospinal fluid.
Topics: Adult; Biological Transport, Active; Humans; Hydroxyindoleacetic Acid; Male; Phenylacetates; Probene | 1969 |
Excretion patterns of tryptamine, indoleacetic acid, and 5-hydroxyindoleacetic acid, and their correlation with mental changes in schizophrenic patients under medication with alpha-methyldopa.
Topics: Adult; Humans; Hydroxyindoleacetic Acid; Hypotension; Indoleacetic Acids; Male; Methyldopa; Middle A | 1969 |
Cerebrospinal fluid monoamine catabolites in drug-induced extrapyramidal disorders.
Topics: Amines; Brain; Chlorpromazine; Extrapyramidal Tracts; Female; Humans; Hydroxyindoleacetic Acid; Move | 1970 |
The content of 5-hydroxyindoleacetic acid and homovanillic acid in the cerebrospinal fluid of patients with acute schizophrenia.
Topics: Adult; Female; Humans; Hydroxyindoleacetic Acid; Male; Paranoid Disorders; Phenylacetates; Schizophr | 1971 |
Relationship of monoamine metabolites in human cerebrospinal fluid to age.
Topics: Adult; Age Factors; Bipolar Disorder; Brain; Depression; Female; Humans; Hydroxyindoleacetic Acid; M | 1968 |
Acid metabolites from monoamines in cerebrospinal fluid of chronic schizophrenics.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Brain; Brain Chemistry; Child; Chlorpromazine; Dopami | 1969 |
[Urinary excretion of 5-hydroxyindoleacetic acid (5-HIAA) in 20 atypical cycloid-type psychoses].
Topics: Adult; Bipolar Disorder; Female; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Schizophrenia; | 1965 |
High-protein, high-carbohydrate diets, and electroshock treatment related to 5-hydroxyindoleacetic acid excretion in schizophrenics and normal controls.
Topics: Adult; Brain; Dietary Carbohydrates; Dietary Proteins; Electroconvulsive Therapy; Female; Humans; Hy | 1966 |
Variations of urinary creatinine and its correlation to excretion of indole metabolites in mental patients.
Topics: Chemistry, Clinical; Circadian Rhythm; Creatine; Humans; Hydroxyindoleacetic Acid; In Vitro Techniqu | 1966 |