hydroxyindoleacetic acid has been researched along with Restless Legs Syndrome in 4 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
Restless Legs Syndrome: A disorder characterized by aching or burning sensations in the lower and rarely the upper extremities that occur prior to sleep or may awaken the patient from sleep.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the role of CNS dopaminergic systems in Restless Legs Syndrome (RLS), homovanillic acid (HVA), tetrahydrobiopterin (BH4), and neopterin (NEOP), were assayed in CSF from RLS patients." | 3.71 | CSF dopamine, serotonin, and biopterin metabolites in patients with restless legs syndrome. ( Allen, RP; Earley, CJ; Hyland, K, 2001) |
| "The symptoms of restless legs syndrome (RLS) have a circadian pattern and central nervous system dopamine has been implicated in the pathogenesis of the condition." | 1.35 | Circadian rhythm of CSF monoamines and hypocretin-1 in restless legs syndrome and Parkinson's disease. ( Engelland, S; Kripke, DF; Parsons, L; Poceta, JS, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Earley, CJ | 2 |
| Hyland, K | 2 |
| Allen, RP | 2 |
| Högl, B | 1 |
| Poceta, JS | 1 |
| Parsons, L | 1 |
| Engelland, S | 1 |
| Kripke, DF | 1 |
4 other studies available for hydroxyindoleacetic acid and Restless Legs Syndrome
| Article | Year |
|---|---|
Circadian changes in CSF dopaminergic measures in restless legs syndrome.
Topics: Biopterins; Chronobiology Disorders; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleaceti | 2006 |
Circadian rhythms in RLS.
Topics: Biopterins; Chronobiology Disorders; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; | 2006 |
Circadian rhythm of CSF monoamines and hypocretin-1 in restless legs syndrome and Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Biogenic Monoamines; Chromatography, High Pressure Liquid; Cir | 2009 |
CSF dopamine, serotonin, and biopterin metabolites in patients with restless legs syndrome.
Topics: Age Factors; Biopterins; Brain; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Aci | 2001 |