Page last updated: 2024-10-21

hydroxyindoleacetic acid and Restless Legs Syndrome

hydroxyindoleacetic acid has been researched along with Restless Legs Syndrome in 4 studies

(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.

Restless Legs Syndrome: A disorder characterized by aching or burning sensations in the lower and rarely the upper extremities that occur prior to sleep or may awaken the patient from sleep.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the role of CNS dopaminergic systems in Restless Legs Syndrome (RLS), homovanillic acid (HVA), tetrahydrobiopterin (BH4), and neopterin (NEOP), were assayed in CSF from RLS patients."3.71CSF dopamine, serotonin, and biopterin metabolites in patients with restless legs syndrome. ( Allen, RP; Earley, CJ; Hyland, K, 2001)
"The symptoms of restless legs syndrome (RLS) have a circadian pattern and central nervous system dopamine has been implicated in the pathogenesis of the condition."1.35Circadian rhythm of CSF monoamines and hypocretin-1 in restless legs syndrome and Parkinson's disease. ( Engelland, S; Kripke, DF; Parsons, L; Poceta, JS, 2009)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Earley, CJ2
Hyland, K2
Allen, RP2
Högl, B1
Poceta, JS1
Parsons, L1
Engelland, S1
Kripke, DF1

Other Studies

4 other studies available for hydroxyindoleacetic acid and Restless Legs Syndrome

ArticleYear
Circadian changes in CSF dopaminergic measures in restless legs syndrome.
    Sleep medicine, 2006, Volume: 7, Issue:3

    Topics: Biopterins; Chronobiology Disorders; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleaceti

2006
Circadian rhythms in RLS.
    Sleep medicine, 2006, Volume: 7, Issue:3

    Topics: Biopterins; Chronobiology Disorders; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid;

2006
Circadian rhythm of CSF monoamines and hypocretin-1 in restless legs syndrome and Parkinson's disease.
    Sleep medicine, 2009, Volume: 10, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Biogenic Monoamines; Chromatography, High Pressure Liquid; Cir

2009
CSF dopamine, serotonin, and biopterin metabolites in patients with restless legs syndrome.
    Movement disorders : official journal of the Movement Disorder Society, 2001, Volume: 16, Issue:1

    Topics: Age Factors; Biopterins; Brain; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Aci

2001