hydroxyindoleacetic acid has been researched along with Panic Disorder in 6 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
Panic Disorder: A type of anxiety disorder characterized by unexpected panic attacks that last minutes or, rarely, hours. Panic attacks begin with intense apprehension, fear or terror and, often, a feeling of impending doom. Symptoms experienced during a panic attack include dyspnea or sensations of being smothered; dizziness, loss of balance or faintness; choking sensations; palpitations or accelerated heart rate; shakiness; sweating; nausea or other form of abdominal distress; depersonalization or derealization; paresthesias; hot flashes or chills; chest discomfort or pain; fear of dying and fear of not being in control of oneself or going crazy. Agoraphobia may also develop. Similar to other anxiety disorders, it may be inherited as an autosomal dominant trait.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the role of serotonin (5-HT) in the pathophysiology of panic disorder (PD) a challenge test with L-5-hydroxytryptophan (5-HTP) was conducted." | 5.08 | Behavioral, neuroendocrine and biochemical effects of different doses of 5-HTP in panic disorder. ( Den Boer, JA; Slaap, BR; van Vliet, IM; Westenberg, HG, 1996) |
| "Phenelzine (PLZ), a nonselective monoamine oxidase inhibitor, is widely used in psychiatry for the treatment of panic disorder and depression." | 3.68 | Chronic administration of the antidepressant-antipanic drug phenelzine and its N-acetylated analogue: effects on monoamine oxidase, biogenic amines, and alpha 2-adrenoreceptor function. ( Baker, GB; Coutts, RT; Greenshaw, AJ; McKenna, KF, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Laine, K | 1 |
| Heikkinen, T | 1 |
| Ekblad, U | 1 |
| Kero, P | 1 |
| Sullivan, GM | 1 |
| Oquendo, MA | 1 |
| Huang, YY | 1 |
| Mann, JJ | 1 |
| Esler, M | 1 |
| Lambert, E | 1 |
| Alvarenga, M | 1 |
| Socratous, F | 1 |
| Richards, J | 1 |
| Barton, D | 1 |
| Pier, C | 1 |
| Brenchley, C | 1 |
| Dawood, T | 1 |
| Hastings, J | 1 |
| Guo, L | 1 |
| Haikerwal, D | 1 |
| Kaye, D | 1 |
| Jennings, G | 1 |
| Kalff, V | 1 |
| Kelly, M | 1 |
| Wiesner, G | 1 |
| Lambert, G | 1 |
| van Vliet, IM | 1 |
| Slaap, BR | 1 |
| Westenberg, HG | 1 |
| Den Boer, JA | 1 |
| Griebel, G | 1 |
| Curet, O | 1 |
| Perrault, G | 1 |
| Sanger, DJ | 1 |
| McKenna, KF | 1 |
| Baker, GB | 1 |
| Coutts, RT | 1 |
| Greenshaw, AJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Transcranial Direct Current Stimulation (tDCS) for Depression in Pregnancy: A Pilot Study[NCT02116127] | 20 participants (Actual) | Interventional | 2014-04-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for hydroxyindoleacetic acid and Panic Disorder
| Article | Year |
|---|---|
Increased brain serotonin turnover in panic disorder patients in the absence of a panic attack: reduction by a selective serotonin reuptake inhibitor.
Topics: Adult; Brain; Case-Control Studies; Catheterization, Central Venous; Catheterization, Peripheral; Ce | 2007 |
Behavioral, neuroendocrine and biochemical effects of different doses of 5-HTP in panic disorder.
Topics: 5-Hydroxytryptophan; Adult; Affect; Dose-Response Relationship, Drug; Double-Blind Method; Female; H | 1996 |
4 other studies available for hydroxyindoleacetic acid and Panic Disorder
| Article | Year |
|---|---|
Effects of exposure to selective serotonin reuptake inhibitors during pregnancy on serotonergic symptoms in newborns and cord blood monoamine and prolactin concentrations.
Topics: Adult; Depressive Disorder; Female; Fetal Blood; Humans; Hydroxyindoleacetic Acid; Infant, Newborn; | 2003 |
Elevated cerebrospinal fluid 5-hydroxyindoleacetic acid levels in women with comorbid depression and panic disorder.
Topics: Adult; Analysis of Variance; Depression; Female; Humans; Hydroxyindoleacetic Acid; Middle Aged; Pani | 2006 |
Behavioral effects of phenelzine in an experimental model for screening anxiolytic and anti-panic drugs: correlation with changes in monoamine-oxidase activity and monoamine levels.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Anti-Anxiety Agents; Biogenic Monoamines; Bites and Stings; | 1998 |
Chronic administration of the antidepressant-antipanic drug phenelzine and its N-acetylated analogue: effects on monoamine oxidase, biogenic amines, and alpha 2-adrenoreceptor function.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antidepressive Agents; Biogenic Amines; Body Weight; Brain; | 1992 |