hydroxyindoleacetic acid has been researched along with Pain in 54 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fibromyalgia (FM) is a prevalent syndrome with chronic pain and a hypothesised underlying disturbance of the tryptophan (TRP) metabolism." | 7.72 | Experimental evaluation of an altered tryptophan metabolism in fibromyalgia. ( Ackenheil, M; Neumeister, A; Offenbaecher, M; Schwarz, MJ, 2003) |
| "Fibromyalgia (FM) is a prevalent syndrome with chronic pain and a hypothesized underlying disturbance of the tryptophan (TRP) metabolism." | 7.71 | Evidence for an altered tryptophan metabolism in fibromyalgia. ( Ackenheil, M; Ewert, T; Lossau, K; Neumeister, A; Offenbaecher, M; Praschak-Rieder, N; Schwarz, MJ; Stucki, G; Weisser, R; Willeit, M; Zach, J; Zacherl, M, 2002) |
| "The aim of the present study was to investigate the discriminative power of a series of variables (including determination of depressive symptomatology by means of a visual analogue scale, determination of personality traits by means of the Karolinska Scales of Personality, determination of monoamine metabolites in CSF, platelet MAO activities, serum cortisol before and after dexamethasone suppression and urinary melatonin) in differentiating chronic pain patients from healthy subjects, and patients with idiopathic pain syndromes from patients with neurogenic pain syndromes." | 7.67 | Discrimination of idiopathic pain syndromes from neurogenic pain syndromes and healthy volunteers by means of clinical rating, personality traits, monoamine metabolites in CSF, serum cortisol, platelet MAO and urinary melatonin. ( Almay, BG; Häggendal, J; Johansson, F; Oreland, L; von Knorring, L; Wetterberg, L, 1986) |
| " To further establish the neurochemical basis for its supraspinally mediated analgesic action, concentrations of spinal noradrenaline, 4-hydroxy-3-methoxyphenylglycol (MHPG), serotonin (5-HT), 5-hydroxyindoleacetic acid (5-HIAA) and dopamine were measured using high-performance liquid chromatography in a murine neuropathic pain model that was prepared by partial ligation of the sciatic nerve (the Seltzer model)." | 3.74 | Neurochemical evidence that supraspinally administered gabapentin activates the descending noradrenergic system after peripheral nerve injury. ( Honda, M; Ono, H; Takasu, K; Takeuchi, Y; Tanabe, M, 2007) |
| "On the basis of these findings, norepinephrine (NE), epinephrine (E), dopamine (DOP), 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA), and vanillylmandelic acid (VMA) concentrations were determined in the cerebrospinal fluid (CSF) in patients with acute (20), chronic (27), and episodic pain syndrome (44) in a prospective study." | 3.73 | [Monoaminergic transmitters in the cerebrospinal fluid of patients with acute, chronic, and intermittent pain. Interface between pain and depression?]. ( Fischer, C; Hoffmann, KH; Meyer, S; Ostertag, D; Paulus, C; Strittmatter, M, 2005) |
| "Fibromyalgia (FM) is a prevalent syndrome with chronic pain and a hypothesised underlying disturbance of the tryptophan (TRP) metabolism." | 3.72 | Experimental evaluation of an altered tryptophan metabolism in fibromyalgia. ( Ackenheil, M; Neumeister, A; Offenbaecher, M; Schwarz, MJ, 2003) |
| "Fibromyalgia (FM) is a prevalent syndrome with chronic pain and a hypothesized underlying disturbance of the tryptophan (TRP) metabolism." | 3.71 | Evidence for an altered tryptophan metabolism in fibromyalgia. ( Ackenheil, M; Ewert, T; Lossau, K; Neumeister, A; Offenbaecher, M; Praschak-Rieder, N; Schwarz, MJ; Stucki, G; Weisser, R; Willeit, M; Zach, J; Zacherl, M, 2002) |
| "The administration to rats of tryptophan (CAS 73-22-3) in high dosage causes a significant increase in pain threshold values." | 3.68 | Potentiation of the analgesic effects of tryptophan by allopurinol in rats. ( Malvezzi, L; Pinelli, A; Trivulzio, S; Zecca, L, 1991) |
| "Rats were fed an artificial diet containing either their normal, or five times their normal, daily requirement of tryptophan for up to five weeks and were tested in an animal model of deafferentation pain, nerve lesion-induced autotomy." | 3.68 | The effect of tryptophan supplementation on autotomy induced by nerve lesions in rats. ( Abbott, FV; Young, SN, 1991) |
| "Guanethidine treatment decreased morphine analgesia exhibited by restrained rats but had no effect on morphine analgesia exhibited by unrestrained rats or on baseline pain sensitivity." | 3.67 | Sympathetic control of tryptophan uptake and morphine analgesia in stressed rats. ( Franklin, KB; Kelly, SJ, 1986) |
| "The aim of the present study was to investigate the discriminative power of a series of variables (including determination of depressive symptomatology by means of a visual analogue scale, determination of personality traits by means of the Karolinska Scales of Personality, determination of monoamine metabolites in CSF, platelet MAO activities, serum cortisol before and after dexamethasone suppression and urinary melatonin) in differentiating chronic pain patients from healthy subjects, and patients with idiopathic pain syndromes from patients with neurogenic pain syndromes." | 3.67 | Discrimination of idiopathic pain syndromes from neurogenic pain syndromes and healthy volunteers by means of clinical rating, personality traits, monoamine metabolites in CSF, serum cortisol, platelet MAO and urinary melatonin. ( Almay, BG; Häggendal, J; Johansson, F; Oreland, L; von Knorring, L; Wetterberg, L, 1986) |
| "Patients with idiopathic pain syndromes were compared with healthy volunteers and with patients suffering from chronic pain syndromes of neurogenic origin, with respect to the concentrations of the metabolites 5-hydroxy-indole-acetic acid (5-HIAA) and homovanillic acid (HVA) in cerebrospinal fluid (CSF)." | 3.67 | 5-HIAA and HVA in CSF in patients with idiopathic pain disorders. ( Almay, BG; Häggendal, J; Oreland, L; von Knorring, L, 1987) |
| "In rats suffering from experimentally induced arthritis produced by Freund's adjuvant, there is a marked decrease in total serum tryptophan levels and a marked increase in plasma-free tryptophan levels at both 15 and 21 days after the administration of the adjuvant." | 3.66 | Total and free serum tryptophan levels and brain 5-hydroxytryptamine metabolism in arthritic rats. ( Besson, JM; Coudert, D; Godefroy, F; Weil-Fugazza, J, 1980) |
| "Lumbar cerebrospinal fluid levels of 5-hydroxyindoleacetic acid, which are used as indicators of central nervous system serotonergic neuronal activity, were significantly higher in 67 patients with chronic pain and in 32 patients with acute pain (23." | 3.66 | Serotonergic activity in man as a function of pain, pain mechanisms, and depression. ( Duncan, GH; Ghia, JN; Mao, W; Mueller, RA; Scott, DS, 1981) |
| "Women diagnosed with breast cancer received massage therapy or practiced progressive muscle relaxation (PMR) for 30-min sessions 3 times a week for 5 weeks or received standard treatment." | 2.71 | Natural killer cells and lymphocytes increase in women with breast cancer following massage therapy. ( Beutler, J; Field, T; Fletcher, MA; Fraser, M; Hernandez-Reif, M; Hurley, J; Ironson, G; Kuhn, C; Schanberg, S; Vera, Y, 2005) |
| " JCM-16021 treatment significantly reduced the 5-HT concentrations (from high, middle and low dosage groups: 60." | 1.36 | Analgesic effects of JCM-16021 on neonatal maternal separation-induced visceral pain in rats. ( Bian, ZX; Han, QB; Sung, JJ; Xu, HX; Zhang, M, 2010) |
| "In all, 115 patients with carcinoid were interviewed." | 1.32 | Relationships among delay of diagnosis, extent of disease, and survival in patients with abdominal carcinoid tumors. ( Pommier, RF; Toth-Fejel, S, 2004) |
| "The catechol signal was significantly increased by 22." | 1.31 | Modulation of noradrenergic and serotonergic transmission by noxious stimuli and intrathecal morphine differs in the dorsal raphe nucleus of anesthetized rat: in vivo voltammetric studies. ( Abe, K; Chuma, T; Kato, M; Miyamoto, K; Miyatake, T; Taguchi, K; Utsunomiya, I, 2002) |
| "The present research examined morphine dose-response effects on both the formalin test and on CNS monoamine (MA) levels and the metabolites dihydroxyphenylacetic acid (DOPAC) and 5-hydroxyindoleacetic acid (5-HIAA) in hypoalgesic (76) and hyperalgesic (SN) strains of domestic fowl." | 1.28 | Central monoaminergic changes induced by morphine in hypoalgesic and hyperalgesic strains of domestic fowl. ( Hoganson, DA; Hughes, RA; Sufka, KJ, 1992) |
| "Among Parkinson's disease (PD) patients complaining of pain, 10 with pain not associated with a motor fluctuation or L-dopa therapy were evaluated." | 1.28 | The threshold of pain and neurotransmitter's change on pain in Parkinson's disease. ( Matsushima, E; Nishikawa, S; Sano, K; Takahashi, K; Takao, T; Urakami, K, 1990) |
| "These arthropathies have been the subject of only a very limited number of publications." | 1.26 | [Joint manifestations of carcinoid tumors of the digestive system]. ( Solnica, J, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (48.15) | 18.7374 |
| 1990's | 14 (25.93) | 18.2507 |
| 2000's | 11 (20.37) | 29.6817 |
| 2010's | 2 (3.70) | 24.3611 |
| 2020's | 1 (1.85) | 2.80 |
| Authors | Studies |
|---|---|
| Li, T | 1 |
| Yue, Y | 1 |
| Ma, Y | 1 |
| Zhong, Z | 1 |
| Guo, M | 1 |
| Zhang, J | 1 |
| Wang, Z | 1 |
| Miao, C | 1 |
| Tong, Q | 1 |
| Zhang, L | 1 |
| Yuan, Y | 1 |
| Jiang, S | 1 |
| Zhang, R | 1 |
| Xu, Q | 1 |
| Ding, J | 1 |
| Li, D | 1 |
| Zhou, X | 1 |
| Zhang, K | 1 |
| Pais-Vieira, M | 1 |
| Mendes-Pinto, MM | 1 |
| Lima, D | 1 |
| Galhardo, V | 1 |
| Bian, ZX | 1 |
| Zhang, M | 1 |
| Han, QB | 1 |
| Xu, HX | 1 |
| Sung, JJ | 1 |
| Chuma, T | 1 |
| Taguchi, K | 2 |
| Kato, M | 2 |
| Abe, K | 1 |
| Utsunomiya, I | 1 |
| Miyamoto, K | 1 |
| Miyatake, T | 1 |
| Schwarz, MJ | 3 |
| Offenbaecher, M | 2 |
| Neumeister, A | 2 |
| Ewert, T | 1 |
| Willeit, M | 1 |
| Praschak-Rieder, N | 1 |
| Zach, J | 1 |
| Zacherl, M | 1 |
| Lossau, K | 1 |
| Weisser, R | 1 |
| Stucki, G | 1 |
| Ackenheil, M | 3 |
| Toth-Fejel, S | 1 |
| Pommier, RF | 1 |
| Strittmatter, M | 1 |
| Ostertag, D | 1 |
| Hoffmann, KH | 1 |
| Paulus, C | 1 |
| Fischer, C | 1 |
| Meyer, S | 1 |
| Hernandez-Reif, M | 1 |
| Field, T | 1 |
| Ironson, G | 1 |
| Beutler, J | 1 |
| Vera, Y | 1 |
| Hurley, J | 1 |
| Fletcher, MA | 1 |
| Schanberg, S | 1 |
| Kuhn, C | 1 |
| Fraser, M | 1 |
| Takeuchi, Y | 1 |
| Takasu, K | 1 |
| Honda, M | 1 |
| Ono, H | 1 |
| Tanabe, M | 1 |
| Ruggieri, V | 1 |
| Vitale, G | 1 |
| Pini, LA | 1 |
| Sandrini, M | 1 |
| Almay, BG | 4 |
| Johansson, F | 4 |
| von Knorring, L | 6 |
| Sedvall, G | 1 |
| Terenius, L | 3 |
| Hosobuchi, Y | 1 |
| Weil-Fugazza, J | 1 |
| Godefroy, F | 1 |
| Coudert, D | 1 |
| Besson, JM | 1 |
| Ghia, JN | 1 |
| Mueller, RA | 2 |
| Duncan, GH | 1 |
| Scott, DS | 1 |
| Mao, W | 1 |
| Ward, NG | 1 |
| Bloom, VL | 1 |
| Dworkin, S | 1 |
| Fawcett, J | 1 |
| Narasimhachari, N | 1 |
| Friedel, RO | 1 |
| Luna, A | 1 |
| Villanueva, E | 1 |
| Hernandez-Cueto, C | 1 |
| Luna, JD | 1 |
| Perris, C | 1 |
| Oreland, L | 4 |
| Eisemann, M | 1 |
| Eriksson, U | 1 |
| Perris, H | 1 |
| McCann, UD | 1 |
| Ridenour, A | 1 |
| Shaham, Y | 1 |
| Ricaurte, GA | 1 |
| Mohanakumar, KP | 1 |
| Mohanty, S | 1 |
| Ganguly, DK | 1 |
| Mendlin, A | 1 |
| Martín, FJ | 1 |
| Rueter, LE | 1 |
| Jacobs, BL | 1 |
| Shigenaga, T | 1 |
| Späth, M | 1 |
| Müller-Bardorff, H | 1 |
| Pongratz, DE | 1 |
| Bondy, B | 1 |
| Li, JY | 1 |
| Wong, CH | 1 |
| Huang, KS | 1 |
| Liang, KW | 1 |
| Lin, MY | 1 |
| Tan, PP | 1 |
| Chen, JC | 1 |
| Hains, BC | 1 |
| Johnson, KM | 1 |
| McAdoo, DJ | 1 |
| Eaton, MJ | 1 |
| Hulsebosch, CE | 1 |
| Yamashiro, T | 1 |
| Fukunaga, T | 1 |
| Kabuto, H | 1 |
| Ogawa, N | 1 |
| Takano-Yamamoto, T | 1 |
| Fernstrom, JD | 1 |
| Solnica, J | 1 |
| Sufka, KJ | 1 |
| Hoganson, DA | 1 |
| Hughes, RA | 1 |
| Murray, CW | 1 |
| Cowan, A | 1 |
| Houvenagel, E | 1 |
| Forzy, G | 1 |
| Leloire, O | 1 |
| Gallois, P | 1 |
| Hary, S | 1 |
| Hautecoeur, P | 1 |
| Convain, L | 1 |
| Henniaux, M | 1 |
| Vincent, G | 1 |
| Dhondt, JL | 1 |
| Garzón, J | 1 |
| Lérida, M | 1 |
| Sánchez-Blázquez, P | 1 |
| Urakami, K | 1 |
| Takahashi, K | 1 |
| Matsushima, E | 1 |
| Sano, K | 1 |
| Nishikawa, S | 1 |
| Takao, T | 1 |
| Hansen, HJ | 1 |
| Thorøe, U | 1 |
| Pinelli, A | 1 |
| Trivulzio, S | 1 |
| Malvezzi, L | 1 |
| Zecca, L | 1 |
| Abbott, FV | 1 |
| Young, SN | 1 |
| Sakurada, T | 1 |
| Post, C | 1 |
| Arweström, E | 1 |
| Minor, BG | 1 |
| Wikberg, JE | 1 |
| Jonsson, G | 1 |
| Archer, T | 1 |
| del Ser, T | 1 |
| Franch, O | 1 |
| Portera, A | 1 |
| Muradas, V | 1 |
| Yebenes, JG | 1 |
| Häggendal, J | 3 |
| Magnusson, T | 1 |
| Almay, B | 1 |
| Franklin, KB | 1 |
| Kelly, SJ | 1 |
| Wetterberg, L | 1 |
| Bero, LA | 1 |
| Kuhn, CM | 1 |
| Steinman, JL | 1 |
| Carlton, SM | 1 |
| Haber, B | 1 |
| Willis, WD | 1 |
| France, RD | 1 |
| Urban, BJ | 1 |
| Pelton, S | 1 |
| Kilts, CD | 1 |
| Hong, JS | 1 |
| Nemeroff, CB | 1 |
| Bourgoin, S | 1 |
| Cesselin, F | 1 |
| Gozlan, H | 1 |
| Fattaccini, CM | 1 |
| Tran, MA | 1 |
| Montastruc, JL | 1 |
| Rascol, A | 1 |
| Hamon, M | 1 |
| De Felipe, MC | 1 |
| Molinero, MT | 1 |
| Del Río, J | 1 |
| Guan, XM | 1 |
| Wang, CY | 1 |
| Liu, XC | 1 |
| Zhang, YW | 1 |
| Zheng, XY | 1 |
| Liang, XC | 1 |
| Li, LL | 1 |
| Spielman, FJ | 1 |
| Corke, BC | 1 |
| Thurston, H | 1 |
| Pohl, JE | 1 |
| Bell, M | 1 |
| Samanin, R | 1 |
| Gumulka, W | 1 |
| Valzelli, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect Of High Intensity Interval Upper Extremity Training On Biochemistry Parameters And Disease Symptoms In Patients With Fibromyalgia[NCT05502003] | 33 participants (Actual) | Interventional | 2022-08-25 | Completed | |||
| The Effects of Osteopathic Manipulations on the Expression Patterns of Immune Cell Biomarkers[NCT03250312] | 40 participants (Actual) | Interventional | 2017-09-13 | Terminated (stopped due to Study Partner Left. Samples degraded before analysis.) | |||
| Hypoalgesic Effects of Specific vs Non-specific Cervical Manipulation in Healthy Subjects[NCT03541538] | 21 participants (Actual) | Interventional | 2018-06-20 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for hydroxyindoleacetic acid and Pain
| Article | Year |
|---|---|
Approaches to neuropeptide and, in particular, endorphin measurements.
Topics: Bipolar Disorder; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Depressive Dis | 1984 |
Effects on the diet on brain neurotransmitters.
Topics: Acetyl Coenzyme A; Acetylcholine; Animals; Brain; Catecholamines; Choline; Choline Deficiency; Diet; | 1977 |
3 trials available for hydroxyindoleacetic acid and Pain
| Article | Year |
|---|---|
Natural killer cells and lymphocytes increase in women with breast cancer following massage therapy.
Topics: Adult; Anger; Anxiety; Breast Neoplasms; Depression; Dopamine; Female; Humans; Hydroxyindoleacetic A | 2005 |
Serotonin neurotoxicity after (+/-)3,4-methylenedioxymethamphetamine (MDMA; "Ecstasy"): a controlled study in humans.
Topics: 3,4-Methylenedioxyamphetamine; Adult; Analysis of Variance; Female; Homovanillic Acid; Humans; Hydro | 1994 |
Low power laser biostimulation of chronic oro-facial pain. A double-blind placebo controlled cross-over study in 40 patients.
Topics: Adult; Aged; Chronic Disease; Double-Blind Method; Facial Pain; Female; Humans; Hydroxyindoleacetic | 1990 |
49 other studies available for hydroxyindoleacetic acid and Pain
| Article | Year |
|---|---|
Fasting-mimicking diet alleviates inflammatory pain by inhibiting neutrophil extracellular traps formation and neuroinflammation in the spinal cord.
Topics: Amidines; Animals; Diet; Extracellular Traps; Fasting; Hydroxyindoleacetic Acid; Mice; Neuroinflamma | 2023 |
Reduced plasma serotonin and 5-hydroxyindoleacetic acid levels in Parkinson's disease are associated with nonmotor symptoms.
Topics: Aged; Biomarkers; Depression; Female; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Pain; Par | 2015 |
Cognitive impairment of prefrontal-dependent decision-making in rats after the onset of chronic pain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amygdala; Animals; Chronic Disease; Cognition; Decision Making; Dise | 2009 |
Analgesic effects of JCM-16021 on neonatal maternal separation-induced visceral pain in rats.
Topics: Administration, Oral; Analgesics; Animals; Animals, Newborn; Anxiety, Separation; Colon; Disease Mod | 2010 |
Modulation of noradrenergic and serotonergic transmission by noxious stimuli and intrathecal morphine differs in the dorsal raphe nucleus of anesthetized rat: in vivo voltammetric studies.
Topics: Animals; Catechols; Electrophysiology; Hindlimb; Hot Temperature; Hydroxyindoleacetic Acid; Injectio | 2002 |
Evidence for an altered tryptophan metabolism in fibromyalgia.
Topics: Adult; Case-Control Studies; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay | 2002 |
Relationships among delay of diagnosis, extent of disease, and survival in patients with abdominal carcinoid tumors.
Topics: Abdominal Neoplasms; Carcinoid Tumor; Diagnostic Errors; Disease Progression; Female; Flushing; Foll | 2004 |
[Monoaminergic transmitters in the cerebrospinal fluid of patients with acute, chronic, and intermittent pain. Interface between pain and depression?].
Topics: Acute Disease; Biogenic Monoamines; Biomarkers; Chronic Disease; Depression; Female; Humans; Hydroxy | 2005 |
Experimental evaluation of an altered tryptophan metabolism in fibromyalgia.
Topics: Adult; Case-Control Studies; Cross-Over Studies; Double-Blind Method; Female; Fibromyalgia; Humans; | 2003 |
Neurochemical evidence that supraspinally administered gabapentin activates the descending noradrenergic system after peripheral nerve injury.
Topics: Amines; Analgesics; Animals; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gaba | 2007 |
Differential involvement of opioidergic and serotonergic systems in the antinociceptive activity of N-arachidonoyl-phenolamine (AM404) in the rat: comparison with paracetamol.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Arachidonic Acids; Frontal Lobe; Hydroxyindoleacet | 2008 |
Relationships between CSF levels of endorphins and monoamine metabolites in chronic pain patients.
Topics: Adult; Aged; Biogenic Amines; Chronic Disease; Endorphins; Female; Homovanillic Acid; Humans; Hydrox | 1980 |
The current status of analgesic brain stimulation.
Topics: Analgesia; Corpus Striatum; Electric Stimulation Therapy; Endorphins; Follow-Up Studies; Humans; Hyd | 1980 |
Total and free serum tryptophan levels and brain 5-hydroxytryptamine metabolism in arthritic rats.
Topics: Animals; Arthritis; Arthritis, Experimental; Brain Chemistry; Hydroxyindoleacetic Acid; Male; Pain; | 1980 |
Serotonergic activity in man as a function of pain, pain mechanisms, and depression.
Topics: Adult; Chronic Disease; Depressive Disorder; Female; Humans; Hydroxyindoleacetic Acid; Male; Middle | 1981 |
Psychobiological markers in coexisting pain and depression: toward a unified theory.
Topics: Anxiety Disorders; Brain; Depressive Disorder; Doxepin; Humans; Hydroxyindoleacetic Acid; Methoxyhyd | 1982 |
[Behavior of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in relation to agonized suffering (I)].
Topics: Forensic Medicine; Humans; Hydroxyindoleacetic Acid; Pain; Pericardial Effusion; Serotonin; Shock; S | 1983 |
Pain as a symptom in depressive disorders and its relationship to platelet monoamine oxidase activity.
Topics: Adult; Bipolar Disorder; Blood Platelets; Depressive Disorder; Female; Humans; Hydroxyindoleacetic A | 1984 |
Neonatal treatment with 5-HT antiserum alters 5-HT metabolism and function in adult rats.
Topics: Animals; Animals, Newborn; Basal Ganglia; Brain; Hydroxyindoleacetic Acid; Immune Sera; Pain; Rats; | 1995 |
Neuronal release of serotonin in the cerebellum of behaving rats: an in vivo microdialysis study.
Topics: Animals; Arousal; Behavior, Animal; Cerebellum; Darkness; Feeding Behavior; Hydroxyindoleacetic Acid | 1996 |
In vivo voltammetric studies of the effects of intrathecal morphine on noxious heat stimuli-induced serotonin release in the nucleus raphe magnus of anesthetized rats.
Topics: Animals; Electrochemistry; Hot Temperature; Hydroxyindoleacetic Acid; Injections, Spinal; Male; Morp | 1997 |
Relationship of substance P, 5-hydroxyindole acetic acid and tryptophan in serum of fibromyalgia patients.
Topics: Adult; Biomarkers; Female; Fibromyalgia; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Pain; | 1999 |
Morphine tolerance in arthritic rats and serotonergic system.
Topics: Analgesics, Opioid; Animals; Arthritis, Experimental; Chronic Disease; Drug Tolerance; Extremities; | 1999 |
Engraftment of serotonergic precursors enhances locomotor function and attenuates chronic central pain behavior following spinal hemisection injury in the rat.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cell Transplantation; Cells, Cultured; Disease Models, A | 2001 |
Activation of the bulbospinal serotonergic system during experimental tooth movement in the rat.
Topics: Animals; Chromatography, High Pressure Liquid; Hydroxyindoleacetic Acid; Male; Medulla Oblongata; Pa | 2001 |
[Joint manifestations of carcinoid tumors of the digestive system].
Topics: Finger Joint; Gastrointestinal Neoplasms; Humans; Hydroxyindoleacetic Acid; Joint Diseases; Malignan | 1976 |
Central monoaminergic changes induced by morphine in hypoalgesic and hyperalgesic strains of domestic fowl.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Brain Chemistry; Chickens; Chromatogra | 1992 |
Formalin nociception in the mouse does not lead to increased spinal serotonin turnover.
Topics: Animals; Disease Models, Animal; Formaldehyde; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred IC | 1990 |
[Cerebrospinal fluid monoamines in primary fibromyalgia].
Topics: Adult; Chronic Disease; Dopamine; Female; Fibromyalgia; Homovanillic Acid; Humans; Hydroxyindoleacet | 1990 |
Effect of intrathecal injection of pertussis toxin on substance P, norepinephrine and serotonin contents in various neural structures of arthritic rats.
Topics: Animals; Arthritis, Experimental; Brain; Freund's Adjuvant; Hydroxyindoleacetic Acid; Injections, Sp | 1990 |
The threshold of pain and neurotransmitter's change on pain in Parkinson's disease.
Topics: Aged; beta-Endorphin; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydr | 1990 |
Potentiation of the analgesic effects of tryptophan by allopurinol in rats.
Topics: Allopurinol; Analgesics; Animals; Brain Chemistry; Chromatography, Liquid; Drug Synergism; Hydroxyin | 1991 |
The effect of tryptophan supplementation on autotomy induced by nerve lesions in rats.
Topics: Animals; Behavior, Animal; Brain Chemistry; Denervation; Hydroxyindoleacetic Acid; Neurons, Afferent | 1991 |
Long-term high frequency transcutaneous electrical nerve stimulation (hi-TNS) in chronic pain. Clinical response and effects on CSF-endorphins, monoamine metabolites, substance P-like immunoreactivity (SPLI) and pain measures.
Topics: Adult; Aged; Chronic Disease; Electric Stimulation Therapy; Endorphins; Female; Follow-Up Studies; G | 1985 |
Noradrenaline depletion increases noradrenaline-induced antinociception in mice.
Topics: Animals; Benzylamines; Dopamine; Hydroxyindoleacetic Acid; Male; Mice; Neural Pathways; Norepinephri | 1985 |
Neurotransmitter changes in cerebrospinal fluid in the Spanish toxic oil syndrome: human clinical findings and experimental results in mice.
Topics: Anilides; Animals; Brain Chemistry; Brassica; Catecholamines; Disease Models, Animal; Foodborne Dise | 1986 |
Relationship between platelet MAO activity and concentrations of 5-HIAA and HVA in cerebrospinal fluid in chronic pain patients.
Topics: Age Factors; Blood Platelets; Body Height; Chronic Disease; Female; Homovanillic Acid; Humans; Hydro | 1986 |
Sympathetic control of tryptophan uptake and morphine analgesia in stressed rats.
Topics: Analgesia; Animals; Guanethidine; Hydroxyindoleacetic Acid; Male; Morphine; Pain; Rats; Restraint, P | 1986 |
Discrimination of idiopathic pain syndromes from neurogenic pain syndromes and healthy volunteers by means of clinical rating, personality traits, monoamine metabolites in CSF, serum cortisol, platelet MAO and urinary melatonin.
Topics: Adult; Chronic Disease; Depressive Disorder; Female; Homovanillic Acid; Humans; Hydrocortisone; Hydr | 1986 |
Role of serotonin in opiate-induced prolactin secretion and antinociception in the developing rat.
Topics: 5,7-Dihydroxytryptamine; Aging; Animals; Animals, Newborn; Cyproheptadine; Hydroxyindoleacetic Acid; | 1987 |
5-HIAA and HVA in CSF in patients with idiopathic pain disorders.
Topics: Adult; Age Factors; Aged; Body Weight; Depressive Disorder; Female; Homovanillic Acid; Humans; Hydro | 1987 |
Differential effects of p-chlorophenylalanine on indoleamines in brainstem nuclei and spinal cord of rats. I. Biochemical and behavioral analysis.
Topics: 5-Hydroxytryptophan; Animals; Brain Stem; Female; Fenclonine; Hydroxyindoleacetic Acid; Organ Specif | 1987 |
CSF monoamine metabolites in chronic pain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Back Pain; Biogenic Amines; Chronic Disease; Depressive | 1987 |
Chronic chlorimipramine does not reverse the reduction of cerebrospinal fluid Met-enkephalin-like immunoreactivity in chronic-pain patients.
Topics: Adult; Aged; Chronic Disease; Clomipramine; Enkephalin, Methionine; Enkephalins; Female; Humans; Hyd | 1987 |
Long-lasting neurochemical and functional changes in rats induced by neonatal administration of substance P antiserum.
Topics: Animals; Animals, Newborn; Antibodies; Blood Pressure; Enkephalin, Methionine; Hydroxyindoleacetic A | 1989 |
[The influence of ACH on the metabolism of 5-HT in the brain during acupuncture analgesia].
Topics: Acetylcholine; Acupuncture Therapy; Animals; Brain; Electric Stimulation Therapy; Hydroxyindoleaceti | 1988 |
Cerebrospinal fluid concentration of 5-hydroxyindoleactic acid in pregnancy.
Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Delivery, Obstetric; Female; Humans; Hydroxyindoleaceti | 1985 |
Chest pain in the carcinoid syndrome.
Topics: Aged; Chlorpromazine; Female; Humans; Hydroxyindoleacetic Acid; Malignant Carcinoid Syndrome; Pain; | 1970 |
Reduced effect of morphine in midbrain raphe lesioned rats.
Topics: Animals; Brain Chemistry; Brain Diseases; Female; Hydroxyindoleacetic Acid; Mesencephalon; Morphine; | 1970 |