hydroxyindoleacetic acid has been researched along with Neuroleptic Malignant Syndrome in 6 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
Neuroleptic Malignant Syndrome: A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA) levels in the cerebrospinal fluid (CSF) were determined twice in nine cases of neuroleptic malignant syndrome (NMS) during the active phase." | 7.68 | Does dantrolene influence central dopamine and serotonin metabolism in the neuroleptic malignant syndrome? A retrospective study. ( Ishiguro, T; Nisijima, K, 1993) |
| "Homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA) levels in the cerebrospinal fluid (CSF) were determined twice in nine cases of neuroleptic malignant syndrome (NMS) during the active phase." | 3.68 | Does dantrolene influence central dopamine and serotonin metabolism in the neuroleptic malignant syndrome? A retrospective study. ( Ishiguro, T; Nisijima, K, 1993) |
| "In 8 cases of typical neuroleptic malignant syndrome (NMS), homovanillic acid (HVA), 5-hydroxyindole acetic acid (5-HIAA), noradrenaline (NA), and 3-methoxy-4-hydroxyphenylethyleneglycol (MHPG) levels in the cerebrospinal fluid (CSF) were assayed during both the active phase of NMS and after recovery." | 3.68 | Neuroleptic malignant syndrome: a study of CSF monoamine metabolism. ( Ishiguro, T; Nisijima, K, 1990) |
| "In nine typical cases and five mild cases of neuroleptic malignant syndrome (NMS), homovanillic acid (HVA), 5-hydroxyindoleacetic acid (5-HIAA) and noradrenaline (NA) and 3-methoxy-4-hydroxyphenylethyleneglycol (MHPG) levels in the cerebrospinal fluid (CSF) were assayed both during the active phase of NMS and after recovery." | 3.67 | [Clinical course and CSF monoamine metabolism in neuroleptic malignant syndrome--a study of nine typical cases and five mild cases]. ( Ishiguro, T; Nishijima, K, 1989) |
| "To determine susceptibility to neuroleptic malignant syndrome (NMS) in patients with PD in relation to central monoamine metabolism." | 1.30 | Susceptibility to neuroleptic malignant syndrome in Parkinson's disease. ( Hamamoto, M; Katayama, Y; Miyazaki, T; Nagayama, H; Nito, C; Otsubo, K; Terashi, A; Ueda, M, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 5 (83.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nisijima, K | 3 |
| Ishiguro, T | 4 |
| Oyafuso, K | 1 |
| Shimada, T | 1 |
| Hosino, H | 1 |
| Ueda, M | 1 |
| Hamamoto, M | 1 |
| Nagayama, H | 1 |
| Otsubo, K | 1 |
| Nito, C | 1 |
| Miyazaki, T | 1 |
| Terashi, A | 1 |
| Katayama, Y | 1 |
| Komatsu, H | 1 |
| Nishimura, A | 1 |
| Okano, S | 1 |
| Miyanomae, Y | 1 |
| Takeuchi, Y | 1 |
| Sawada, T | 1 |
| Nishijima, K | 1 |
6 other studies available for hydroxyindoleacetic acid and Neuroleptic Malignant Syndrome
| Article | Year |
|---|---|
Does dantrolene influence central dopamine and serotonin metabolism in the neuroleptic malignant syndrome? A retrospective study.
Topics: Adult; Dantrolene; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Midd | 1993 |
Cerebrospinal fluid monoamine metabolism in a case of neuroleptic malignant syndrome improved by electroconvulsive therapy.
Topics: Antidepressive Agents; Antipsychotic Agents; Depressive Disorder; Electroconvulsive Therapy; Female; | 1996 |
Susceptibility to neuroleptic malignant syndrome in Parkinson's disease.
Topics: Aged; Aged, 80 and over; Disease Susceptibility; Female; Homovanillic Acid; Humans; Hydroxyindoleace | 1999 |
Neuroleptic malignant syndrome-like state in a patient with Down syndrome and basal ganglia calcification.
Topics: Adolescent; Basal Ganglia Diseases; Calcinosis; Down Syndrome; Homovanillic Acid; Humans; Hydroxyind | 1992 |
Neuroleptic malignant syndrome: a study of CSF monoamine metabolism.
Topics: Adult; Biogenic Monoamines; Bipolar Disorder; Depressive Disorder; Female; Homovanillic Acid; Humans | 1990 |
[Clinical course and CSF monoamine metabolism in neuroleptic malignant syndrome--a study of nine typical cases and five mild cases].
Topics: Adult; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphe | 1989 |