hydroxyindoleacetic acid has been researched along with Neoplasms in 45 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to evaluate the efficacy and safety of ondansetron, an antagonist of 5-hydroxytryptamine type 3 (serotonin 3) (5-HT3) receptors, in controlling nausea and vomiting induced by antineoplastic therapy in children affected by cancer." | 7.68 | Ondansetron, an antagonist of 5-HT3 receptors, in the treatment of antineoplastic drug-induced nausea and vomiting in children. ( Calabria, C; Casale, F; Di Tullio, M; Indolfi, P; Lampa, E; Lucarelli, C; Matera, MG; Rossi, F, 1993) |
| " Carcinoid tumors with liver metastases, especially those of midgut origin, produce serotonin via the precursors tryptophan and 5-hydroxytryptophan (5-HTP) and this overproduction contributes to the clinical symptoms of the carcinoid syndrome." | 5.07 | Positron emission tomography (PET) in neuroendocrine gastrointestinal tumors. ( Ahlström, H; Bergström, M; Eriksson, B; Långström, B; Lilja, A; Oberg, K, 1993) |
| "These preliminary findings suggest that an elevated pretreatment ratio of substance P to 5-HIAA/creatinine >70 is associated with the development of delayed vomiting induced by MEC." | 3.78 | Identification of a novel marker associated with risk for delayed chemotherapy-induced vomiting. ( Auber, ML; Higa, GM; Hobbs, G, 2012) |
| "The aim of this study was to evaluate the efficacy and safety of ondansetron, an antagonist of 5-hydroxytryptamine type 3 (serotonin 3) (5-HT3) receptors, in controlling nausea and vomiting induced by antineoplastic therapy in children affected by cancer." | 3.68 | Ondansetron, an antagonist of 5-HT3 receptors, in the treatment of antineoplastic drug-induced nausea and vomiting in children. ( Calabria, C; Casale, F; Di Tullio, M; Indolfi, P; Lampa, E; Lucarelli, C; Matera, MG; Rossi, F, 1993) |
| " BSA-guided dosing is important." | 2.73 | Population pharmacokinetic-pharmacodynamic model of the vascular-disrupting agent 5,6-dimethylxanthenone-4-acetic acid in cancer patients. ( Baguley, BC; Baker, SD; Jameson, MB; Li, J; Pili, R, 2008) |
| "In patients with cancer (n = 16), baseline blood dialysate 5-HIAA concentrations averaged 2." | 2.69 | Use of intravenous microdialysis to monitor changes in serotonin release and metabolism induced by cisplatin in cancer patients: comparative effects of granisetron and ondansetron. ( Castejon, AM; Cubeddu, LX; Hernandez, L; Paez, X, 1999) |
| "Six of the 8 carcinoid patients had radiographic changes of increased necrosis." | 2.67 | Somatostatin analogue phase I trials in neuroendocrine neoplasms. ( Anthony, L; Hande, K; Johnson, D; Krozely, M; Oates, J; Shaff, M; Winn, S, 1993) |
| "Recently, anticancer drugs that act by selectively disrupting tumour blood flow have been found to increase plasma 5HT concentrations in mice." | 1.31 | Measurement of plasma 5-hydroxyindoleacetic acid as a possible clinical surrogate marker for the action of antivascular agents. ( Baguley, BC; Folkes, LK; Jameson, MB; Kestell, P; Stratford, MR; Zhao, L, 2001) |
| "Twenty-five patients with solid tumors received, after myeloblative chemotherapy, a total of 30 reinfusions of PBSC and/or bone marrow." | 1.30 | Effects of peripheral stem cell or bone marrow reinfusion on peripheral serotonin metabolism. ( Kema, IP; Mulder, NH; Smit Sibinga, CT; van der Graaf, WT; Vries, EG; Wymenga, AN, 1999) |
| "But it is also high in non-cancer patients such as liver cirrhosis, diabetes mellitus and cholelithiasis occasionally." | 1.27 | [A rapid method for determining urinary indoleacetic acid concentration and its clinical significance as the tumor-marker in the diagnosis of malignant diseases]. ( Kobayashi, T; Kobori, K; Maruyama, K; Sakakibara, H; Yamaki, T, 1983) |
| "The patients with cancer had higher platelet MAO activity and lower urinary excretion of 5-HIAA, sertonin and tyramine than the healthy subjects." | 1.26 | Effect of metastatic cancer on platelet monoamine oxidase activity and serotonin metabolism. ( Feldman, JM, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (66.67) | 18.7374 |
| 1990's | 9 (20.00) | 18.2507 |
| 2000's | 3 (6.67) | 29.6817 |
| 2010's | 3 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diamandis, P | 1 |
| Wildenhain, J | 1 |
| Clarke, ID | 1 |
| Sacher, AG | 1 |
| Graham, J | 1 |
| Bellows, DS | 1 |
| Ling, EK | 1 |
| Ward, RJ | 1 |
| Jamieson, LG | 1 |
| Tyers, M | 1 |
| Dirks, PB | 1 |
| Nakamura, H | 1 |
| Yokoyama, H | 1 |
| Yoshimoto, K | 1 |
| Nakajima, A | 1 |
| Okuyama, K | 1 |
| Iwase, O | 1 |
| Yamada, Y | 1 |
| Rendu, F | 1 |
| Peoc'h, K | 1 |
| Berlin, I | 1 |
| Thomas, D | 1 |
| Launay, JM | 1 |
| Higa, GM | 1 |
| Auber, ML | 1 |
| Hobbs, G | 1 |
| HEGGLIN, R | 1 |
| LANGEMANN, H | 2 |
| HEILMEYER, L | 1 |
| KUHN, HA | 1 |
| CLOTTEN, R | 1 |
| LIPP, A | 1 |
| GOERRE, J | 1 |
| ZYLKA, W | 1 |
| KOHLER, T | 1 |
| TEICHMANN, W | 1 |
| SCHMIDT, G | 1 |
| BARONI, G | 1 |
| CIPRIANI, D | 1 |
| SANTILLI, E | 1 |
| LUETHI, U | 1 |
| WENZL, H | 1 |
| WASER, PG | 1 |
| BRAASCH, JW | 1 |
| DENBO, HE | 1 |
| SJOERDSMA, A | 1 |
| MELMON, KL | 1 |
| DREUX, C | 2 |
| DELAUNEUX, B | 1 |
| KHALAFALLAH, AS | 1 |
| ABUL-FADL, MA | 1 |
| DOUCHETTE, JW | 1 |
| ESTES, WB | 1 |
| SORRENTINO, F | 1 |
| ROMANO, C | 1 |
| SAURAMO, H | 1 |
| REISSELL, P | 1 |
| BECKER, V | 1 |
| URELES, AL | 1 |
| MURRAY, M | 1 |
| Li, J | 1 |
| Jameson, MB | 2 |
| Baguley, BC | 2 |
| Pili, R | 1 |
| Baker, SD | 1 |
| Kobori, K | 1 |
| Sakakibara, H | 1 |
| Maruyama, K | 1 |
| Kobayashi, T | 1 |
| Yamaki, T | 1 |
| Eriksson, B | 1 |
| Bergström, M | 1 |
| Lilja, A | 1 |
| Ahlström, H | 1 |
| Långström, B | 1 |
| Oberg, K | 1 |
| Anthony, L | 1 |
| Johnson, D | 1 |
| Hande, K | 1 |
| Shaff, M | 1 |
| Winn, S | 1 |
| Krozely, M | 1 |
| Oates, J | 1 |
| Cubeddu, LX | 3 |
| Hoffmann, IS | 2 |
| Matera, MG | 1 |
| Di Tullio, M | 1 |
| Lucarelli, C | 1 |
| Casale, F | 1 |
| Calabria, C | 1 |
| Lampa, E | 1 |
| Indolfi, P | 1 |
| Rossi, F | 1 |
| Nobels, FR | 1 |
| Kwekkeboom, DJ | 1 |
| Coopmans, W | 1 |
| Schoenmakers, CH | 1 |
| Lindemans, J | 1 |
| De Herder, WW | 1 |
| Krenning, EP | 1 |
| Bouillon, R | 1 |
| Lamberts, SW | 1 |
| Wymenga, AN | 1 |
| van der Graaf, WT | 1 |
| Kema, IP | 1 |
| Smit Sibinga, CT | 1 |
| Vries, EG | 1 |
| Mulder, NH | 1 |
| Castejon, AM | 1 |
| Paez, X | 1 |
| Hernandez, L | 1 |
| Kestell, P | 1 |
| Zhao, L | 1 |
| Stratford, MR | 1 |
| Folkes, LK | 1 |
| Talavdekar, RV | 1 |
| Feldman, JM | 1 |
| Bousquet, B | 1 |
| Girard, ML | 1 |
| Cubeddu, L | 1 |
| Hoffmann, I | 1 |
| Fuenmayor, N | 1 |
| Fuenmayor, NT | 1 |
| Malave, JJ | 1 |
| González-Navarro, A | 1 |
| Zimman Mansfeld, H | 1 |
| Molinero Aparicio, T | 1 |
| González Hernandez, MJ | 1 |
| González Maté, A | 1 |
| Borque-Ibarra, M | 1 |
| Seijo, F | 1 |
| Melcón, LF | 1 |
| Simó, RM | 1 |
| Madrid, JL | 2 |
| Fatela, LV | 2 |
| Lobato, RD | 2 |
| Gozalo, A | 2 |
| Sarabia, R | 1 |
| Rivas, JJ | 1 |
| Sergeeva, TI | 1 |
| Raushenbakh, TI | 1 |
| Shevchenko, MO | 1 |
| Rybal'chenko, VG | 1 |
| Basu, TK | 1 |
| Raven, RW | 1 |
| Bates, C | 1 |
| Williams, DC | 1 |
| Schwartz, MK | 1 |
| Schein, PS | 1 |
| O'Connell, MJ | 1 |
| Blom, J | 1 |
| Hubbard, S | 1 |
| Magrath, IT | 1 |
| Bergevin, P | 1 |
| Wiernik, PH | 1 |
| Ziegler, JL | 1 |
| DeVita, VT | 1 |
| Kretschmer, H | 1 |
| Fiorentino, E | 1 |
| Pietropaolo, C | 1 |
| Calì, G | 1 |
3 reviews available for hydroxyindoleacetic acid and Neoplasms
| Article | Year |
|---|---|
Smoking related diseases: the central role of monoamine oxidase.
Topics: Anxiety; Biomarkers; Cardiovascular Diseases; Depression; Epigenesis, Genetic; Humans; Hydroxyindole | 2011 |
DIAGNOSIS AND MANAGEMENT OF MALIGNANT CARCINOID SYNDROME: A REVIEW.
Topics: Humans; Hydroxyindoleacetic Acid; Malignant Carcinoid Syndrome; Neoplasm Metastasis; Neoplasms; Sele | 1964 |
Biochemical procedures in different forms of cancer.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acid Phosphatase; Adrenal Gland Neoplasms; Alkaline Phos | 1971 |
6 trials available for hydroxyindoleacetic acid and Neoplasms
| Article | Year |
|---|---|
Method for individualized evaluation of antiemetic effect induced by 5-HT3 receptor antagonist.
Topics: Aged; Antiemetics; Creatinine; Female; Granisetron; Humans; Hydroxyindoleacetic Acid; Intestine, Sma | 2013 |
Population pharmacokinetic-pharmacodynamic model of the vascular-disrupting agent 5,6-dimethylxanthenone-4-acetic acid in cancer patients.
Topics: Adult; Aged; Antineoplastic Agents; Area Under Curve; Blood Vessels; Dose-Response Relationship, Dru | 2008 |
Positron emission tomography (PET) in neuroendocrine gastrointestinal tumors.
Topics: 5-Hydroxytryptophan; Adenoma, Islet Cell; Carbon Radioisotopes; Carcinoid Tumor; Female; Gastrointes | 1993 |
Somatostatin analogue phase I trials in neuroendocrine neoplasms.
Topics: Adult; Aged; Amino Acid Sequence; Antineoplastic Agents; Carcinoid Tumor; Dose-Response Relationship | 1993 |
Use of intravenous microdialysis to monitor changes in serotonin release and metabolism induced by cisplatin in cancer patients: comparative effects of granisetron and ondansetron.
Topics: Adult; Aged; Antineoplastic Agents; Cisplatin; Female; Granisetron; Humans; Hydroxyindoleacetic Acid | 1999 |
Clinical antitumor activity and toxicity of streptozotocin (NSC-85998).
Topics: Adenoma, Islet Cell; Blood Cells; Burkitt Lymphoma; Carcinoid Tumor; Carmustine; Clinical Trials as | 1974 |
36 other studies available for hydroxyindoleacetic acid and Neoplasms
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
Identification of a novel marker associated with risk for delayed chemotherapy-induced vomiting.
Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Biomarkers; Case-Control Studies; Creatinine; Dexam | 2012 |
[Clinical manifestations and detection of 5-hydroxy-indolacetic acid and 5-hydroxy-tryptamine in metastasizing carcinoid of the small intestine].
Topics: Blood; Carcinoid Tumor; Hydroxyindoleacetic Acid; Indoleacetic Acids; Intestine, Small; Intestines; | 1955 |
[Metastasizing carcinoid of the small intestine with detection of hydroxyindoleacetic acid in blood and urine by high tension electrophoresis].
Topics: Blood; Carcinoid Tumor; Electrophoresis; Gastrointestinal Tract; Hydroxyindoleacetic Acid; Indoleace | 1956 |
SEROTONIN, 5-hydroxyindoleacetic acid and cancer.
Topics: Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Neoplasms; Serotonin | 1957 |
[Suppression of hydroxyindole-acetic acid excretion in urine after reserpine administration in humans; with special consideration to carcinoid syndrome].
Topics: Acetates; Carcinoid Tumor; Gastrointestinal Tract; Hydroxyindoleacetic Acid; Indoleacetic Acids; Mal | 1957 |
[Application of various methods for quantitative determination of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in a case of metastasizing carcinoid of the small intestine].
Topics: Carcinoid Tumor; Hydroxyindoleacetic Acid; Indoleacetic Acids; Intestine, Small; Neoplasms; Serotoni | 1957 |
[Additional remarks on the detection of 5-hydroxyindoleacetic acid, with some notes on the paper A simple test for diagnosis of metastatic carcinoma].
Topics: Carcinoid Tumor; Hydroxyindoleacetic Acid; Indoleacetic Acids; Intestine, Small; Intestines; Neoplas | 1957 |
[Urinary elimination of 5-hydroxyindolacetic acid in different aspects of human pathology].
Topics: Cardiovascular Diseases; Gastroenterology; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Kid | 1962 |
[THE STORAGE OF C14-LABELLED TRYPTOPHAN IN A METASTASIZING SMALL INTESTINE CARCINOID].
Topics: Autoradiography; Carbon Isotopes; Hydroxyindoleacetic Acid; Intestine, Small; Malignant Carcinoid Sy | 1964 |
TUMORS OF THE SMALL INTESTINE.
Topics: Adenocarcinoma; Angiomatosis; Carcinoid Tumor; Humans; Hydroxyindoleacetic Acid; Ileum; Indoleacetic | 1964 |
THE CARCINOID SPECTRUM.
Topics: 5-Hydroxytryptophan; Angiotensins; Antineoplastic Agents; Bronchial Neoplasms; Carcinoid Tumor; Chlo | 1964 |
[CRITICAL STUDY OF BIOCHEMICAL METHODS OF EXPLORATION OF SEROTONIN METABOLISM. TECHNICS OF DETERMINATION OF URINARY 5-HYDROXYINDOLACETIC ACID].
Topics: Blood Chemical Analysis; Carcinoid Tumor; Chemistry Techniques, Analytical; Chromatography; Hydroxyi | 1964 |
STUDIES ON THE URINARY EXCRETION OF CERTAIN TRYPTOPHAN METABOLITES BEFORE AND AFTER TRYPTOPHAN LOADING DOSE IN BILHARZIASIS, BILHARZIAL BLADDER CANCER AND CERTAIN OTHER TYPES OF MALIGNANCIES IN EGYPT.
Topics: Amino Acids; Egypt; Epidemiology; Fluids and Secretions; Humans; Hydroxyindoleacetic Acid; Indoleace | 1964 |
PRIMARY OVARIAN CARCINOID TUMORS: CASE REPORT AND REVIEW OF THE LITERATURE.
Topics: Carcinoid Tumor; Dermoid Cyst; Female; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Neoplas | 1965 |
3-INDOLACETIC ACID (IAA) AND 5-HYDROXY-INDOLACETIC ACID (5HIAA) EXCRETION IN PATIENTS WITH VESICAL TUMOURS.
Topics: Fluids and Secretions; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Neoplasms; Statistics a | 1965 |
5-Hydroxyindole acetic acid during pregnancy and puerperium, in newborn infants, and gynaecological tumours.
Topics: Acetates; Female; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Indoles; Infant, Newborn; Ne | 1960 |
[A rapid method for determining urinary indoleacetic acid concentration and its clinical significance as the tumor-marker in the diagnosis of malignant diseases].
Topics: Chromatography, High Pressure Liquid; Female; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; | 1983 |
Participation of serotonin on early and delayed emesis induced by initial and subsequent cycles of cisplatinum-based chemotherapy: effects of antiemetics.
Topics: Adult; Cisplatin; Dexamethasone; Dose-Response Relationship, Drug; Female; Humans; Hydroxyindoleacet | 1993 |
Ondansetron, an antagonist of 5-HT3 receptors, in the treatment of antineoplastic drug-induced nausea and vomiting in children.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Humans; Hydroxyindoleacetic | 1993 |
Chromogranin A as serum marker for neuroendocrine neoplasia: comparison with neuron-specific enolase and the alpha-subunit of glycoprotein hormones.
Topics: Adult; Aged; Biomarkers, Tumor; Carcinoid Tumor; Carcinoma, Medullary; Carcinoma, Small Cell; Chromo | 1997 |
Effects of peripheral stem cell or bone marrow reinfusion on peripheral serotonin metabolism.
Topics: Adult; Blood Platelets; Bone Marrow Transplantation; Female; Flushing; Hematopoietic Stem Cell Trans | 1999 |
Measurement of plasma 5-hydroxyindoleacetic acid as a possible clinical surrogate marker for the action of antivascular agents.
Topics: Angiogenesis Inhibitors; Biomarkers; Calibration; Chromatography, High Pressure Liquid; Clinical Tri | 2001 |
Biochemical tests in the diagnosis of cancer.
Topics: 17-Ketosteroids; Acid Phosphatase; Alkaline Phosphatase; alpha-Fetoproteins; Bence Jones Protein; Fe | 1975 |
Effect of metastatic cancer on platelet monoamine oxidase activity and serotonin metabolism.
Topics: Adult; Aged; Blood Platelets; Female; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Monoamine | 1979 |
[The importance of determining 5-hydroxytryptophan and hydroxyindoles in biological fluids in cancer cases].
Topics: 5-Hydroxytryptophan; Body Fluids; Chromatography, Ion Exchange; Humans; Hydroxyindoleacetic Acid; Ne | 1975 |
Serotonin and emesis--from animals to humans: a discussion of Professor Naylor's paper.
Topics: Animals; Cisplatin; Cyclophosphamide; Dogs; Ferrets; Humans; Hydroxyindoleacetic Acid; Neoplasms; Se | 1992 |
Changes in serotonin metabolism in cancer patients: its relationship to nausea and vomiting induced by chemotherapeutic drugs.
Topics: Adult; Analysis of Variance; Antineoplastic Agents; Blood Platelets; Cisplatin; Cyclophosphamide; Do | 1992 |
[Use of beta-endorphin in pain in cancer patients].
Topics: beta-Endorphin; Dose-Response Relationship, Drug; Drug Evaluation; Endorphins; Humans; Hydroxyindole | 1987 |
[Determination of the levels of methionine enkephalin in the blood and CSF and of 5-hydroxyindoleacetic acid in the CSF, following intrathecal administration of morphine].
Topics: Aged; Enkephalin, Methionine; Female; Humans; Hydroxyindoleacetic Acid; Injections, Spinal; Male; Mi | 1985 |
Intrathecal therapy: rationale, technique, clinical results.
Topics: Adolescent; Adult; Aged; Child; Cisterna Magna; Female; Homovanillic Acid; Humans; Hydroxyindoleacet | 1987 |
Intraventricular morphine for intractable cancer pain: rationale, methods, clinical results.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Inf | 1987 |
[Excretion of 5-hydroxyindole-3-acetic and 5-methoxyindole-3-acetic acids in cancer patients].
Topics: Humans; Hydroxyindoleacetic Acid; Neoplasms; Reference Values; Serotonin | 1987 |
Excretion of 5-hydroxyindole acetic acid and n1-methylnicotinamide in advanced cancer patients.
Topics: Aged; Humans; Hydroxyindoleacetic Acid; Middle Aged; Neoplasms; Niacinamide; Tryptophan | 1973 |
[Possibilities of neoplasm diagnosis by the determination of clostridium antibodies].
Topics: Agglutination Tests; Antibody Formation; Catecholamines; Chorionic Gonadotropin; Clinical Enzyme Tes | 1972 |
[Excretion of 5-hydroxyindoleacetic acid in normal and pathological conditions].
Topics: Asthma; Carcinoid Tumor; Hemochromatosis; Hemorrhage; Humans; Hydroxyindoleacetic Acid; Hypertension | 1966 |