hydroxyindoleacetic acid has been researched along with Myoclonic Jerk in 42 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the purported role of central monoamine disturbances in the pathophysiology of the opsoclonus-myoclonus syndrome, the serotonin metabolite 5-hydroxyindoleacetic acid and the dopamine metabolite homovanillic acid were measured in cerebrospinal fluid samples from 27 affected children and 47 age- and gender-matched control subjects by high-pressure liquid chromatography with electrochemical detection." | 9.08 | Cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in the pediatric opsoclonus-myoclonus syndrome. ( Banasiak, K; Gospe, SM; Huang, Y; Noetzel, MJ; Pranzatelli, MR; Stanley, M; Tate, E, 1995) |
| "To study the purported role of central monoamine disturbances in the pathophysiology of the opsoclonus-myoclonus syndrome, the serotonin metabolite 5-hydroxyindoleacetic acid and the dopamine metabolite homovanillic acid were measured in cerebrospinal fluid samples from 27 affected children and 47 age- and gender-matched control subjects by high-pressure liquid chromatography with electrochemical detection." | 5.08 | Cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in the pediatric opsoclonus-myoclonus syndrome. ( Banasiak, K; Gospe, SM; Huang, Y; Noetzel, MJ; Pranzatelli, MR; Stanley, M; Tate, E, 1995) |
| "The administration of veratramine produced generalized tremor, myoclonus, hindlimb abduction, backward gait and Straub tail, similar to the "5-hydroxytryptamine (5-HT) syndrome", in mice." | 3.68 | Veratramine-induced behavior associated with serotonergic hyperfunction in mice. ( Izumi, K; Nagata, R, 1991) |
| "A single dose of p-chloroamphetamine, 10 mg per kilogram, produced postural abnormalities, tremor, myoclonus, and autonomic signs in rats 5 minutes after intraperitoneal injection." | 3.65 | Postural changes, tremor, and myoclonus in the rat immediately following injections of p-chloromaphetamine. ( Growdon, JH, 1977) |
| "Three patients with postanoxic intention myoclonus, two patients with intention tremor, and one patient with cerebral palsy were administered L-5-hydroxytryptophan (L-5HTP), the precursor of serotonin, in combination with MK 486, a peripheral amino acid decarboxylase inhibitor." | 3.65 | Therapy of intention myoclonus with L-5-hydroxytryptophan and a peripheral decarboxylase inhibitor, MK 486. ( Sethy, VH; Van Woert, MH, 1975) |
| "In 6 patients with intention myoclonus, the cerebrospinal fluid concentration of 5-hydroxyindoleacetic acid, a metabolite of serotonin was found to be significantly decreased." | 2.64 | Serotonin and myoclonus. ( Bowers, MB; Jutkowitz, R; Rosenbaum, D; Van Woert, MH, 1976) |
| "The literature on myoclonus and serotonin neuropharmacology reveals evidence for serotonergic abnormalities in some human myoclonic disorders, new serotonin receptor subtypes and data on their molecular structure and function, more selective drugs, and experimental evidence linking certain serotonin receptor subtypes with myoclonus." | 2.39 | Serotonin and human myoclonus. Rationale for the use of serotonin receptor agonists and antagonists. ( Pranzatelli, MR, 1994) |
| "Clonazepam is a potent anticonvulsant 1,4-benzodiazepine that controls some types of myoclonus." | 2.37 | Mechanism of action of clonazepam in myoclonus in relation to effects on GABA and 5-HT. ( Jenner, P; Marsden, CD; Pratt, JA, 1986) |
| "Children with the opsoclonus-myoclonus syndrome (OMS) usually respond to corticotropin (adrenocorticotrophic hormone, ACTH) treatment but the mechanism of benefit is unknown." | 1.30 | Monoaminergic effects of high-dose corticotropin in corticotropin-responsive pediatric opsoclonus-myoclonus. ( Goldstein, DS; Goldstein, EM; Holmes, CS; Huang, YY; Ketner, K; Kinast, M; Lange, BM; Pranzatelli, MR; Sanz, A; Shevell, MI; Stanford, RE; Taff, IP; Tate, E, 1998) |
| "Some types of intention myoclonus respond to serotonin precursor therapy (e." | 1.27 | Fluoxetine in the treatment of intention myoclonus. ( Chung, E; Magnussen, I; Rosenbaum, D; Van Woert, MH, 1983) |
| "Indoleamine-induced myoclonus in guinea pigs is a specific model of brainstem 5-HT function that can be used to characterize the indoleamine systems initiating myoclonus." | 1.27 | 5-HT-mediated myoclonus in the guinea pig as a model of brainstem 5-HT and tryptamine receptor action. ( Jenner, P; Luscombe, G; Marsden, CD, 1986) |
| "p,p'-DDT-induced myoclonus in mice has been proposed as a model of stimulus-sensitive action myoclonus responsive to L-5-HTP and clonazepam treatment." | 1.27 | p,p'-DDT-induced myoclonus in the rat and its application as an animal model of 5-HT-sensitive action myoclonus. ( Jenner, P; Marsden, CD; Pratt, JA; Rothwell, J, 1986) |
| "Posthypoxic action myoclonus is usually associated with impaired serotonin (5-HT) neurotransmission but in some patients 5-HT precursors aggravate and 5-HT blockers improve action myoclonus." | 1.27 | Clinical, biochemical, and pharmacological observation in a patient with postasphyxic myoclonus: association to serotonin hyperactivity. ( De Yebenes, JG; Giménez-Roldán, S; Mateo, D; Muradas, V, 1988) |
| "5-Hydroxyindoleacetic acid was significantly lower in patients with myoclonic DAT as compared to patients with nonmyoclonic DAT, but not significantly lower than in control subjects." | 1.27 | Cerebrospinal fluid neurochemistry in the myoclonic subtype of Alzheimer's disease. ( Atack, JR; Beal, MF; Daly, E; Friedland, RP; Kaufman, S; Kaye, JA; May, C; Milstien, S; Rapoport, SI; Sweeney, DL, 1988) |
| "6 Chloralose-induced myoclonus is not similar to 5-HT-sensitive reticular reflex myoclonus in man." | 1.26 | Observations on chloralose-induced myoclonus in guinea-pigs. ( Chadwick, D; Hallett, M; Jenner, P; Marsden, CD, 1980) |
| "A patient representing with palatal myoclonus was diagnosed as suffering from possible multiple sclerosis." | 1.26 | [Palatal myoclonus associated with a decrease in 5-hydroxy-indole acetic acid in cerebrospinal fluid and responding to clonazepam]. ( Baxter, DW; Gauthier, S; Young, SN, 1981) |
| "Postanoxic myoclonus was first accepted as being related to a dysfunction of the ventrolateral thalamic nucleus." | 1.26 | Postanoxic myoclonus. Treatment of a case with 5-hydroxytryptophane and a decarboxylase inhibitor. ( Beretta, E; de Crousaz, G; Regli, F; Steck, AJ, 1981) |
| "This form of myoclonus therefore is not of relevance to the 5-HT-sensitive post-anoxic action myoclonus occurring in man." | 1.26 | 5-Hydroxytryptamine and myoclonus induced by 1,2-di-hydroxybenzene (catechol) in the guinea-pig. ( Chadwick, D; Jenner, P; Marsden, CD, 1979) |
| "p,p'-DDT-treated rats had increased concentrations of 5-hydroxyindoleacetic acid (5-HIAA) in seven regional areas, but serotonin was increased only in the midbrain and cerebellum." | 1.26 | p,p'-DDT-induced neurotoxic syndrome: experimental myoclonus. ( Hwang, EC; Van Woert, MH, 1978) |
| "The neurochemical basis of myoclonus responding to 5HT precursors and clonazepam is discussed." | 1.26 | Clinical, biochemical, and physiological features distinguishing myoclonus responsive to 5-hydroxytryptophan, tryptophan with a monoamine oxidase inhibitor, and clonazepam. ( Chadwick, D; Hallett, M; Harris, R; Jenner, P; Marsden, CD; Reynolds, EH, 1977) |
| "In two patients with postanoxic action myoclonus, L-tryptophan or a monoamine oxidase inhibitor induced a moderate improvement, but L-5-hydroxytryptophan had greater therapeutic effect." | 1.26 | Beneficial effects of serotonin precursors in postanoxic action myoclonus. ( De Léan, J; Hornykiewicz, O; Richardson, JC, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 36 (85.71) | 18.7374 |
| 1990's | 6 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chadwick, D | 6 |
| Hallett, M | 3 |
| Jenner, P | 10 |
| Marsden, CD | 10 |
| Gauthier, S | 1 |
| Young, SN | 1 |
| Baxter, DW | 1 |
| Beretta, E | 1 |
| Regli, F | 1 |
| de Crousaz, G | 1 |
| Steck, AJ | 1 |
| Van Woert, MH | 8 |
| Magnussen, I | 2 |
| Lowe, YH | 1 |
| Hwang, EC | 2 |
| Rosenbaum, D | 3 |
| Chung, E | 1 |
| Luscombe, G | 2 |
| Pranzatelli, MR | 3 |
| Huang, Y | 1 |
| Tate, E | 2 |
| Stanley, M | 1 |
| Noetzel, MJ | 1 |
| Gospe, SM | 1 |
| Banasiak, K | 1 |
| Matsumoto, RR | 1 |
| Aziz, N | 1 |
| Truong, DD | 1 |
| Huang, YY | 1 |
| Goldstein, DS | 1 |
| Holmes, CS | 1 |
| Goldstein, EM | 1 |
| Ketner, K | 1 |
| Kinast, M | 1 |
| Lange, BM | 1 |
| Sanz, A | 1 |
| Shevell, MI | 1 |
| Stanford, RE | 1 |
| Taff, IP | 1 |
| Reynolds, EH | 3 |
| Stewart, RM | 1 |
| Campbell, A | 1 |
| Sperk, G | 1 |
| Baldessarini, RJ | 1 |
| Levin, SL | 1 |
| Harris, R | 1 |
| Chung Hwang, E | 1 |
| Jankovic, J | 1 |
| Rivera, VM | 1 |
| Growdon, JH | 1 |
| McMillen, BA | 1 |
| Isaac, L | 1 |
| Jutkowitz, R | 1 |
| Bowers, MB | 1 |
| Koskiniemi, M | 1 |
| Sethy, VH | 1 |
| De Léan, J | 2 |
| Richardson, JC | 2 |
| Hornykiewicz, O | 1 |
| Thal, L | 1 |
| Sharpless, N | 1 |
| Wolfson, L | 1 |
| Engel, J | 1 |
| Katzman, R | 1 |
| Nagata, R | 2 |
| Izumi, K | 2 |
| Iwata, S | 1 |
| Shimizu, T | 1 |
| Fukuda, T | 1 |
| Chung, EY | 2 |
| Fahn, S | 1 |
| Rewcastle, NB | 1 |
| Pratt, JA | 2 |
| Rothwell, J | 1 |
| Giménez-Roldán, S | 1 |
| Mateo, D | 1 |
| Muradas, V | 1 |
| De Yebenes, JG | 1 |
| Kaye, JA | 1 |
| May, C | 1 |
| Atack, JR | 1 |
| Daly, E | 1 |
| Sweeney, DL | 1 |
| Beal, MF | 1 |
| Kaufman, S | 1 |
| Milstien, S | 1 |
| Friedland, RP | 1 |
| Rapoport, SI | 1 |
| Shohami, E | 1 |
| Evron, S | 1 |
| Fischer-Perroudon, C | 1 |
| Mouret, J | 1 |
| Jouvet, M | 1 |
| Rohmer, F | 1 |
| Warter, JM | 1 |
| Coquillat, G | 1 |
| Maitrot, D | 1 |
| Kurtz, D | 1 |
| Micheletti, G | 1 |
| Mack, G | 1 |
| Mandel, P | 1 |
| Guilleminault, C | 1 |
| Tharp, BR | 1 |
| Cousin, D | 1 |
2 reviews available for hydroxyindoleacetic acid and Myoclonic Jerk
| Article | Year |
|---|---|
Serotonin and human myoclonus. Rationale for the use of serotonin receptor agonists and antagonists.
Topics: 5-Hydroxytryptophan; Brain; Humans; Hydroxyindoleacetic Acid; Myoclonus; Receptors, Serotonin; Serot | 1994 |
Mechanism of action of clonazepam in myoclonus in relation to effects on GABA and 5-HT.
Topics: 5-Hydroxytryptophan; Animals; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Brain; Clonazepam | 1986 |
3 trials available for hydroxyindoleacetic acid and Myoclonic Jerk
| Article | Year |
|---|---|
Cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in the pediatric opsoclonus-myoclonus syndrome.
Topics: Adrenal Cortex Hormones; Child; Child, Preschool; Chromatography, High Pressure Liquid; Electrochemi | 1995 |
Serotonin and myoclonus.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Carbidopa; Clinical Trials as Topic; Epilepsy; Female; Homov | 1976 |
[Pharmacological and biochemical approach to a syndrome of action and intention myoclonus in the course of degenerative disease of the nervous system].
Topics: 5-Hydroxytryptophan; Adult; Benzazepines; Cerebellar Ataxia; Clinical Trials as Topic; Diagnosis, Di | 1973 |
37 other studies available for hydroxyindoleacetic acid and Myoclonic Jerk
| Article | Year |
|---|---|
Observations on chloralose-induced myoclonus in guinea-pigs.
Topics: Animals; Brain Chemistry; Chloralose; Electroencephalography; Electromyography; Female; Guinea Pigs; | 1980 |
[Palatal myoclonus associated with a decrease in 5-hydroxy-indole acetic acid in cerebrospinal fluid and responding to clonazepam].
Topics: Benzodiazepinones; Clonazepam; Female; Humans; Hydroxyindoleacetic Acid; Middle Aged; Multiple Scler | 1981 |
Postanoxic myoclonus. Treatment of a case with 5-hydroxytryptophane and a decarboxylase inhibitor.
Topics: 5-Hydroxytryptophan; Benserazide; Humans; Hydrazines; Hydroxyindoleacetic Acid; Hypoxia; Male; Middl | 1981 |
Study of serotonin in neuropsychiatric disorders.
Topics: 5-Hydroxytryptophan; Carbidopa; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Kinetic | 1982 |
Fluoxetine in the treatment of intention myoclonus.
Topics: 5-Hydroxytryptophan; Adult; Blood Platelets; Carbidopa; Female; Fluoxetine; Humans; Hydroxyindoleace | 1983 |
Alterations in brain 5HT and tryptamine content during indoleamine-induced myoclonus in guinea pigs.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain; Carbidopa; Drug Interactions; Female; Guinea | 1983 |
Association between brain indole levels and severity of posthypoxic myoclonus in rats.
Topics: 5-Hydroxytryptophan; Analysis of Variance; Animals; Brain; Hydroxyindoleacetic Acid; Hypoxia, Brain; | 1995 |
Monoaminergic effects of high-dose corticotropin in corticotropin-responsive pediatric opsoclonus-myoclonus.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenocorticotropic Hormone; Catecholamines; Child, Preschool; Dihyd | 1998 |
Proceedings: Clonazepam-induced changes in 5-hydroxytryptamine (5-HT) metabolism in aminals and man.
Topics: Animals; Benzodiazepinones; Clonazepam; Humans; Hydroxyindoleacetic Acid; Mice; Myoclonus; Serotonin | 1975 |
5-Hydroxytryptamine and myoclonus induced by 1,2-di-hydroxybenzene (catechol) in the guinea-pig.
Topics: Animals; Brain Chemistry; Catechols; Female; Guinea Pigs; Hydroxyindoleacetic Acid; Male; Myoclonus; | 1979 |
Receptor mechanisms in increased sensitivity to serotonin agonists after dihydroxytryptamine shown by electronic monitoring of muscle twitches in the rat.
Topics: 5-Hydroxytryptophan; 5,7-Dihydroxytryptamine; Animals; Brain; Cyproheptadine; Denervation; Desiprami | 1979 |
[Serotoninergic conception of myoclonic syndromes. (Review)].
Topics: 5-Hydroxytryptophan; Animals; Brain; Brain Chemistry; Carbidopa; Dogs; Electroencephalography; Elect | 1979 |
Altered 5-HT metabolism with clonazepam, diazepam and diphenylhydantoin.
Topics: Animals; Benzodiazepinones; Brain; Clonazepam; Diazepam; Humans; Hydroxyindoleacetic Acid; Male; Mic | 1975 |
p,p'-DDT-induced neurotoxic syndrome: experimental myoclonus.
Topics: 5-Hydroxytryptophan; Animals; Brain Chemistry; Clomipramine; DDT; Hydroxyindoleacetic Acid; Isomeris | 1978 |
Clinical, biochemical, and physiological features distinguishing myoclonus responsive to 5-hydroxytryptophan, tryptophan with a monoamine oxidase inhibitor, and clonazepam.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Benzodiazepinones; Carbidopa; Child, Preschool; Clonaz | 1977 |
Antimyoclonic action of clonazepam: the role of serotonin.
Topics: Animals; Anticonvulsants; Benzodiazepinones; Clonazepam; DDT; Hydroxyindoleacetic Acid; Male; Mice; | 1979 |
Hereditary myoclonus and progressive distal muscular atrophy.
Topics: Adult; Aged; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Muscular Atrophy; My | 1979 |
Postural changes, tremor, and myoclonus in the rat immediately following injections of p-chloromaphetamine.
Topics: Amphetamines; Animals; Dose-Response Relationship, Drug; Hydroxyindoleacetic Acid; Male; Motor Activ | 1977 |
Relationship between kindled myoclonic seizures and feline brain dopamine metabolism.
Topics: Animals; Brain; Cats; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Female; Homovanil | 1978 |
Findings in routine laboratory examination in progressive myoclonus epilepsy.
Topics: Adolescent; Adult; Age Factors; Blood Glucose; Blood Proteins; Cerebrospinal Fluid Proteins; Child; | 1975 |
Therapy of intention myoclonus with L-5-hydroxytryptophan and a peripheral decarboxylase inhibitor, MK 486.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Cer | 1975 |
Beneficial effects of serotonin precursors in postanoxic action myoclonus.
Topics: 5-Hydroxytryptophan; Aged; Carbidopa; Female; Humans; Hydroxyindoleacetic Acid; Hypoxia; Levodopa; M | 1976 |
Clinical and metabolic observations on the treatment of myoclonus with L-5-HTP and carbidopa.
Topics: 5-Hydroxytryptophan; Adult; Carbidopa; Drug Evaluation; Homovanillic Acid; Humans; Hydrazines; Hydro | 1976 |
Veratramine-induced behavior associated with serotonergic hyperfunction in mice.
Topics: 5,6-Dihydroxytryptamine; Animals; Brain Chemistry; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbre | 1991 |
Mechanisms of veratramine-induced 5-HT syndrome in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Aci | 1991 |
Biochemistry and therapeutics of posthypoxic myoclonus.
Topics: 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Aspartic Acid; Benzodiazepines; Carbidopa; Electro | 1986 |
Treatment of posthypoxic action myoclonus: implications for the pathophysiology of the disorder.
Topics: 5-Hydroxytryptophan; Benzodiazepines; Clonazepam; Female; Fenclonine; Humans; Hydroxyindoleacetic Ac | 1986 |
Newer drugs for posthypoxic action myoclonus: observations from a well-studied case.
Topics: Clonazepam; Drug Therapy, Combination; Estrogens, Conjugated (USP); Fasting; Female; Humans; Hydroxy | 1986 |
Pathological findings in a case of hypoxic myoclonus treated with 5-hydroxytryptophan and a decarboxylase inhibitor.
Topics: 5-Hydroxytryptophan; Aged; Brain; Carbidopa; Diazepam; Electroencephalography; Female; Fenclonine; H | 1986 |
5-HT-mediated myoclonus in the guinea pig as a model of brainstem 5-HT and tryptamine receptor action.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain; Carbidopa; Disease Models, Animal; Guinea Pig | 1986 |
p,p'-DDT-induced myoclonus in the rat and its application as an animal model of 5-HT-sensitive action myoclonus.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain; Clonazepam; DDT; Disease Models, Animal; Elec | 1986 |
Possible mechanisms of action of valproic acid in myoclonus.
Topics: 4-Aminobutyrate Transaminase; 5-Hydroxytryptophan; Animals; Brain; gamma-Aminobutyric Acid; Glycine; | 1986 |
Clinical, biochemical, and pharmacological observation in a patient with postasphyxic myoclonus: association to serotonin hyperactivity.
Topics: 5-Hydroxytryptophan; Aged; Humans; Hydroxyindoleacetic Acid; Hypoxia; Male; Methysergide; Myoclonus; | 1988 |
Cerebrospinal fluid neurochemistry in the myoclonic subtype of Alzheimer's disease.
Topics: Acetylcholinesterase; Aged; Alzheimer Disease; Analysis of Variance; Biopterins; Female; Homovanilli | 1988 |
Intrathecal morphine induces myoclonic seizures in the rat.
Topics: Analgesics; Animals; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Injections, Spinal; Male | 1985 |
[Case of agrypnia (4 months without sleep) in Morvan's disease. Favorable action of 5-hydroxytryptophan].
Topics: 5-Hydroxytryptophan; Adult; Chorea; Dose-Response Relationship, Drug; Electroconvulsive Therapy; Ele | 1974 |
HVA and 5HIAA CSF measurements and 5HTP trials in some patients with involuntary movements.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Chorea; Dopamine; Dystonia Musculorum Deformans; Femal | 1973 |