hydroxyindoleacetic acid has been researched along with Muscle Rigidity in 6 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
Muscle Rigidity: Continuous involuntary sustained muscle contraction which is often a manifestation of BASAL GANGLIA DISEASES. When an affected muscle is passively stretched, the degree of resistance remains constant regardless of the rate at which the muscle is stretched. This feature helps to distinguish rigidity from MUSCLE SPASTICITY. (From Adams et al., Principles of Neurology, 6th ed, p73)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seven cases of the infantile form of Huntington's disease--six boys and one girl--were observed in the space of six years." | 1.26 | Seven cases of Huntington's disease in childhood and levodopa induced improvement in the hypokinetic--rigid form. ( Gabreëls, FJ; Jongen, PJ; Renier, WO, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Willemsen, MA | 1 |
| Verbeek, MM | 1 |
| Kamsteeg, EJ | 1 |
| de Rijk-van Andel, JF | 1 |
| Aeby, A | 1 |
| Blau, N | 1 |
| Burlina, A | 1 |
| Donati, MA | 1 |
| Geurtz, B | 1 |
| Grattan-Smith, PJ | 1 |
| Haeussler, M | 1 |
| Hoffmann, GF | 1 |
| Jung, H | 1 |
| de Klerk, JB | 1 |
| van der Knaap, MS | 1 |
| Kok, F | 1 |
| Leuzzi, V | 1 |
| de Lonlay, P | 1 |
| Megarbane, A | 1 |
| Monaghan, H | 1 |
| Renier, WO | 2 |
| Rondot, P | 1 |
| Ryan, MM | 1 |
| Seeger, J | 1 |
| Smeitink, JA | 1 |
| Steenbergen-Spanjers, GC | 1 |
| Wassmer, E | 1 |
| Weschke, B | 1 |
| Wijburg, FA | 1 |
| Wilcken, B | 1 |
| Zafeiriou, DI | 1 |
| Wevers, RA | 1 |
| Jongen, PJ | 1 |
| Gabreëls, FJ | 1 |
| McLellan, DL | 1 |
| Chalmers, RJ | 1 |
| Johnson, RH | 1 |
| Ahtee, L | 1 |
| Kääriäinen, I | 1 |
| Paasonen, MK | 1 |
| Chase, TN | 1 |
| Woods, AC | 1 |
| Glaubiger, GA | 1 |
| Parkes, JD | 1 |
| Marsden, CD | 1 |
| Rees, JE | 1 |
| Curzon, G | 1 |
| Kantamaneni, BD | 1 |
| Knill-Jones, R | 1 |
| Akbar, A | 1 |
| Das, S | 1 |
| Kataria, M | 1 |
2 trials available for hydroxyindoleacetic acid and Muscle Rigidity
| Article | Year |
|---|---|
Clinical and pharmacological evaluation of the effects of piribedil in patients with parkinsonism.
Topics: Aged; Antiparkinson Agents; Chorea; Clinical Trials as Topic; Confusion; Dioxoles; Dopamine; Drug Ev | 1975 |
Parkinson disease treated with a suspected dopamine receptor agonist.
Topics: Adult; Aged; Amantadine; Aromatic Amino Acid Decarboxylase Inhibitors; Benztropine; Dihydroxyphenyla | 1974 |
4 other studies available for hydroxyindoleacetic acid and Muscle Rigidity
| Article | Year |
|---|---|
Tyrosine hydroxylase deficiency: a treatable disorder of brain catecholamine biosynthesis.
Topics: Age of Onset; Amino Acid Metabolism, Inborn Errors; Brain; Brain Diseases; Catecholamines; Child, Pr | 2010 |
Seven cases of Huntington's disease in childhood and levodopa induced improvement in the hypokinetic--rigid form.
Topics: Adolescent; Child; Child, Preschool; Female; Homovanillic Acid; Humans; Huntington Disease; Hydroxyi | 1980 |
Effect of nalorphine and antiparkinsonian drugs on methadone-induced rigidity; relation to homovanillic acid content of nucleus caudatus.
Topics: Amantadine; Animals; Atropine; Body Temperature; Brain; Caudate Nucleus; Depression, Chemical; Dose- | 1972 |
Parkinson's disease, cerebral arteriosclerosis, and senile dementia. Clinical features and response to levodopa.
Topics: Aged; Dementia; Dihydroxyphenylalanine; Electroencephalography; Female; Gait; Homovanillic Acid; Hum | 1974 |