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hydroxyindoleacetic acid and Mental Disorders

hydroxyindoleacetic acid has been researched along with Mental Disorders in 106 studies

(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.

Mental Disorders: Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.

Research Excerpts

ExcerptRelevanceReference
"Limited neurobiological data have implicated central arginine vasopressin in the pathobiology of obsessive-compulsive disorder (OCD)."7.69Elevated cerebrospinal fluid levels of oxytocin in obsessive-compulsive disorder. Comparison with Tourette's syndrome and healthy controls. ( Anderson, GM; Chappell, PB; Goodman, WK; Leckman, JF; McDougle, CJ; McSwiggan-Hardin, M; North, WG; Pauls, DL; Price, LH; Riddle, MA, 1994)
" For example, hypothesized serotonergic deficits in alcoholism, endorphin deficits in opioid dependence, and dopamine depletion in cocaine dependence all might predispose to depression."4.78Hypothesized neurochemical models for psychiatric syndromes in alcohol and drug dependence. ( Extein, IL; Gold, MS, 1993)
"The CSF AVP level was correlated directly with life history of general aggression and aggression against persons and inversely with PRL[d-FEN] responses (but not with CSF 5-hydroxyindoleacetic acid), which in turn was correlated inversely with these 2 measures of life history of aggression."3.70Cerebrospinal fluid vasopressin levels: correlates with aggression and serotonin function in personality-disordered subjects. ( Coccaro, EF; Cooper, TB; Ferris, CF; Hauger, RL; Kavoussi, RJ, 1998)
"Limited neurobiological data have implicated central arginine vasopressin in the pathobiology of obsessive-compulsive disorder (OCD)."3.69Elevated cerebrospinal fluid levels of oxytocin in obsessive-compulsive disorder. Comparison with Tourette's syndrome and healthy controls. ( Anderson, GM; Chappell, PB; Goodman, WK; Leckman, JF; McDougle, CJ; McSwiggan-Hardin, M; North, WG; Pauls, DL; Price, LH; Riddle, MA, 1994)
"Among treatment-seeking alcoholics, early age at onset is generally associated with a more severe course of alcoholism and lower cerebrospinal fluid 5-hydroxyindoleacetic acid concentration."3.69Early-onset alcoholics have lower cerebrospinal fluid 5-hydroxyindoleacetic acid levels than late-onset alcoholics. ( Brown, GL; Eckardt, MJ; Fils-Aime, ML; George, DT; Linnoila, M; Mefford, I, 1996)
"Among all offenders, low cerebrospinal fluid (CSF) 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) concentrations were associated with a family history positive for paternal alcoholism with violence."3.69A prospective follow-up study of alcoholic violent offenders and fire setters. ( Eggert, M; Linnoila, M; Rawlings, R; Virkkunen, M, 1996)
"5-Hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) were measured in the lumbar cerebrospinal fluid of 57 drug-free female patients with DSM-III diagnoses of major unipolar or bipolar depression (n = 14), schizophrenic disorder (n = 18), alcohol dependence (n = 13) and a group of other disorders (n = 12)."3.66Amine metabolites and neuroendocrine responses related to depression and suicide. ( Arató, M; Banki, CM, 1983)
"Treatment with ritanserin appeared to be ineffective."2.67Serotonin function in panic disorder: a double blind placebo controlled study with fluvoxamine and ritanserin. ( Den Boer, JA; Westenberg, HG, 1990)
"Psychiatric diagnosis was made according to DSM-IIIR criteria and assessment of suicide intent with Beck's Suicidal Intent Scale (SIS)."1.31Biogenic amine turnover and serum cholesterol in suicide attempt. ( Agouridaki, M; Markianos, M; Sarantidis, D; Tripodianakis, J, 2002)
"In 26 patients with psychiatric disorders, EEG, and visual averaged evoked responses (VAER) were recorded."1.26Neurophysiological measures related to levels of 5-hydroxyindoleacetic acid, homovanillic acid and tryptophan in cerebrospinal fluid of psychiatric patients. ( Gottfries, CG; Perris, C; von Knorring, L, 1976)

Research

Studies (106)

TimeframeStudies, this research(%)All Research%
pre-199063 (59.43)18.7374
1990's26 (24.53)18.2507
2000's10 (9.43)29.6817
2010's7 (6.60)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shilov, IuE1
Bezrukov, MV1
Vermeiren, Y1
Janssens, J1
Aerts, T1
Martin, JJ1
Sieben, A1
Van Dam, D1
De Deyn, PP1
Samaco, RC1
Mandel-Brehm, C1
Chao, HT1
Ward, CS1
Fyffe-Maricich, SL1
Ren, J1
Hyland, K1
Thaller, C1
Maricich, SM1
Humphreys, P1
Greer, JJ1
Percy, A1
Glaze, DG1
Zoghbi, HY1
Neul, JL1
Gianaros, PJ1
Manuck, SB1
Saijoh, K4
Katsuyama, H4
Moberg, T1
Nordström, P1
Forslund, K1
Kristiansson, M1
Asberg, M5
Jokinen, J1
Luykx, JJ1
Bakker, SC1
Lentjes, E1
Neeleman, M1
Strengman, E1
Mentink, L1
DeYoung, J1
de Jong, S1
Sul, JH1
Eskin, E1
van Eijk, K1
van Setten, J1
Buizer-Voskamp, JE1
Cantor, RM1
Lu, A1
van Amerongen, M1
van Dongen, EP1
Keijzers, P1
Kappen, T1
Borgdorff, P1
Bruins, P1
Derks, EM1
Kahn, RS1
Ophoff, RA1
Malone, KM1
Waternaux, C1
Haas, GL1
Cooper, TB2
Li, S1
Mann, JJ6
Laine, K1
Heikkinen, T1
Ekblad, U1
Kero, P1
TODRICK, A1
DICK, M1
TAIT, AC1
BUSCAINO, GA1
STEFANACHI, L1
LJUNGBERG, E1
KIRBERGER, E1
Ebuehi, OA1
Bishop, SA1
Fanmuyiwa, OO1
Akinwande, AI1
Ladenegan, OA1
Zalsman, G1
Huang, YY1
Harkavy-Friedman, JM1
Oquendo, MA1
Ellis, SP1
Gilligan, J1
Lee, B1
Banshchikov, VM1
Stoliarov, GV1
Hirose, M1
Gateless, D1
Stanley, M5
Träskman-Bendz, L5
Gilroy, J1
Leckman, JF3
Cohen, DJ3
Shaywitz, BA3
Caparulo, BK3
Heninger, GR1
Bowers, MB8
Sedvall, G4
Fyrö, B2
Gullberg, B1
Nybäck, H3
Wiesel, FA4
Wode-Helgodt, B2
Macfie, C1
von Knorring, L3
Perris, C4
Sturges, JS1
Bertilsson, L2
Lantto, O1
Scalia-Tomba, GP1
Tybring, G1
Buchsbaum, MS1
Haier, RJ1
Korf, J2
van den Burg, W1
van den Hoofdakker, RH1
Banki, CM2
Arató, M2
Ninan, PT1
van Kammen, DP2
Scheinin, M2
Linnoila, M6
Bunney, WE1
Goodwin, FK3
Papp, Z1
Kurcz, M1
Iselius, L1
Oreland, L1
Oxenstierna, G1
Ross, SB1
Potter, WZ2
van Kempen, GM1
Extein, IL1
Gold, MS1
Faustman, WO2
Ringo, DL2
Faull, KF3
Lindley, SE1
Goodman, WK1
North, WG1
Chappell, PB1
Price, LH1
Pauls, DL1
Anderson, GM1
Riddle, MA1
McSwiggan-Hardin, M1
McDougle, CJ1
Francis, PT1
Pangalos, MN1
Stephens, PH1
Bartlett, JR2
Bridges, PK2
Malizia, AL1
Neary, D1
Procter, AW1
Thomas, DJ1
Bowen, DM1
Blennow, K2
Wallin, A1
Gottfries, CG4
Månsson, JE1
Svennerholm, L1
Higley, JD1
Thompson, WW1
Champoux, M1
Goldman, D2
Hasert, MF1
Kraemer, GW1
Scanlan, JM1
Suomi, SJ1
Manji, HK1
Davis, BA2
Durden, DA2
Pease, K1
Yu, PH1
Green, C1
Gordon, A1
Menzies, R1
Templeman, R1
Boulton, AA1
Fils-Aime, ML1
Eckardt, MJ1
George, DT1
Brown, GL2
Mefford, I1
Virkkunen, M2
Eggert, M1
Rawlings, R1
Jönsson, E1
Brené, S1
Gustavsson, JP1
Geijer, T1
Terenius, L1
Crocq, MA1
Lannfelt, L1
Tylec, A1
Sokoloff, P1
Schwartz, JC1
Fall, PA1
Ekman, R1
Granérus, AK1
Thorell, LH1
Wålinder, J1
Coccaro, EF1
Kavoussi, RJ1
Hauger, RL1
Ferris, CF1
Kaye, WH1
Greeno, CG1
Moss, H1
Fernstrom, J1
Fernstrom, M1
Lilenfeld, LR1
Weltzin, TE1
Payet, J1
Bouvard, MP1
Chotai, J1
Lappalainen, J1
Long, JC1
Ozaki, N1
Engström, G1
Alling, C1
Regnéll, G1
Stanley, B3
Molcho, A1
Winchel, R1
Gameroff, MJ1
Parsons, B1
Lidberg, L1
Belfrage, H1
Evenden, MM1
Tripodianakis, J1
Markianos, M1
Sarantidis, D1
Agouridaki, M1
Roccatagliata, G1
Albano, C1
Cocito, L1
Maffini, M1
Billiard, M1
Guilleminault, C1
Dement, WC1
Study, RE1
Kirstein, L1
Heninger, G1
Van Praag, HM1
Sepping, P1
Kantamaneni, BD1
Curzon, G2
Jimerson, DC1
Gordon, EK3
Post, RM2
McBride, PA1
Brown, RP2
Leon, AC1
DeMeo, M1
Mieczkowski, T1
Myers, JE1
Gibbons, RD1
Davis, JM1
Hedeker, DR1
Den Boer, JA1
Westenberg, HG1
O'Reilly, RL1
Roy, A1
Jennings, WS1
Schulz, SC1
Narasimhachari, N1
Hamer, RM1
Friedel, RO1
Edman, G1
Levander, S1
Schalling, D1
Carney, MW1
Blumenthal, SJ1
Kupfer, DJ1
Monk, M1
Joborn, C1
Hetta, J1
Rastad, J1
Agren, H1
Akerström, G1
Ljunghall, S1
Matthews, B1
Brown, L1
Csernansky, JG1
Pfefferbaum, A1
Ashcroft, GW1
Crawford, TB1
Eccleston, D1
Sharman, DF1
MacDougall, EJ1
Stanton, JB1
Binns, JK1
Schnur, JA2
Chase, TN2
Brody, JA2
Gumpert, J1
Sharpe, D1
Hornykiewicz, O1
Roos, BE1
Oliver, J1
Lehmann, J1
Major, LF1
Wilson, WP1
Molnár, G1
Fodor, A1
Karczag, I1
Szilágyi, A1
Ujvárosi, I1
Lowenbach, H1
Shore, JH1
Chase, RN1
Jacobsson, L1
Ottosson, JO1
Valcourt, AJ1
Dienstbier, E1
Balík, J1
Duchon, J1
Fischer, O1
Yuwiler, A1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Transcranial Direct Current Stimulation (tDCS) for Depression in Pregnancy: A Pilot Study[NCT02116127]20 participants (Actual)Interventional2014-04-30Completed
[NCT00004325]200 participants Observational1988-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

18 reviews available for hydroxyindoleacetic acid and Mental Disorders

ArticleYear
[Kynurenines in pathogenesis of endogenous psychiatric disorders].
    Vestnik Rossiiskoi akademii meditsinskikh nauk, 2013, Issue:1

    Topics: Humans; Hydroxyindoleacetic Acid; Kynurenine; Mental Disorders; Psychotic Disorders; Tryptophan; Xan

2013
Neurobiological pathways linking socioeconomic position and health.
    Psychosomatic medicine, 2010, Volume: 72, Issue:5

    Topics: Brain; Chronic Disease; Health Status Disparities; Healthcare Disparities; Humans; Hydroxyindoleacet

2010
The psychopharmacologic treatment of violent youth.
    Annals of the New York Academy of Sciences, 2004, Volume: 1036

    Topics: Adolescent; Antipsychotic Agents; Child; Humans; Hydroxyindoleacetic Acid; Hyperthyroidism; Mental D

2004
[5-Hydroxyindole acetic acid (5HIAA)].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 8

    Topics: Biomarkers; Carcinoid Tumor; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrome

2005
The year ... psychiatry.
    The Medical journal of Australia, 1980, May-03, Volume: 1, Issue:9

    Topics: Affective Symptoms; Behavior Therapy; Brain; Electroconvulsive Therapy; Humans; Hydroxyindoleacetic

1980
Psychopathology: biological approaches.
    Annual review of psychology, 1983, Volume: 34

    Topics: Adoption; Adrenocorticotropic Hormone; Antipsychotic Agents; Brain; Dexamethasone; Diseases in Twins

1983
Genetic studies of CSF monoamine metabolites.
    Advances in biochemical psychopharmacology, 1984, Volume: 39

    Topics: Biogenic Amines; Blood Platelets; Dopamine beta-Hydroxylase; Female; Homovanillic Acid; Humans; Hydr

1984
Psychotherapeutic drugs and biogenic amines. Current concepts and therapeutic implications.
    Drugs, 1984, Volume: 28, Issue:2

    Topics: Antidepressive Agents; Biogenic Amines; Dopamine; Humans; Hydroxyindoleacetic Acid; Mental Disorders

1984
[Serotonin in neurology and psychiatry].
    Nederlands tijdschrift voor geneeskunde, 1995, Oct-14, Volume: 139, Issue:41

    Topics: Brain; Brain Chemistry; Humans; Hydroxyindoleacetic Acid; Mental Disorders; Monoamine Oxidase; Recep

1995
Hypothesized neurochemical models for psychiatric syndromes in alcohol and drug dependence.
    Journal of addictive diseases, 1993, Volume: 12, Issue:3

    Topics: Alcoholism; Brain Diseases; Cocaine; Comorbidity; Diagnosis, Dual (Psychiatry); Dopamine; Dopamine A

1993
[5-hydroxyindole acetic acid (5HIAA)].
    Nihon rinsho. Japanese journal of clinical medicine, 1999, Volume: 57 Suppl

    Topics: Biomarkers; Humans; Hydroxyindoleacetic Acid; Mental Disorders

1999
Postmortem evidence for serotonin's role in suicide.
    The Journal of clinical psychiatry, 1990, Volume: 51 Suppl

    Topics: Adolescent; Adult; Age Factors; Brain; Brain Chemistry; Humans; Hydroxyindoleacetic Acid; Mental Dis

1990
Suicide and psychiatric patients.
    The Psychiatric clinics of North America, 1985, Volume: 8, Issue:2

    Topics: Adult; Affective Disorders, Psychotic; Alcoholism; Blood Platelets; Emergency Services, Psychiatric;

1985
Neuropharmacology of S-adenosyl methionine.
    Clinical neuropharmacology, 1986, Volume: 9, Issue:3

    Topics: Animals; Antidepressive Agents; Biogenic Amines; Brain; Dementia; Depressive Disorder; Epilepsy; Fol

1986
Epidemiology of suicide.
    Epidemiologic reviews, 1987, Volume: 9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Humans; Hydroxyindoleacetic Acid; Male; Mental D

1987
A clinical perspective on the role of neurotransmitters in mental disorders.
    Hospital & community psychiatry, 1985, Volume: 36, Issue:2

    Topics: Antidepressive Agents; Brain Chemistry; Cyclic AMP; Depressive Disorder; Dopamine; Electroconvulsive

1985
Monoamine metabolites in human cerebrospinal fluid: indicators of neuronal activity?
    Medical biology, 1985, Volume: 63, Issue:1

    Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Biogenic Amines; Brain Diseases; Glycols; Homo

1985
Clinical psychiatry.
    Progress in neurology and psychiatry, 1969, Volume: 24

    Topics: Ambulatory Care; Anxiety Disorders; Brain Chemistry; Child; Community Mental Health Services; Depres

1969

Trials

2 trials available for hydroxyindoleacetic acid and Mental Disorders

ArticleYear
Serotonin function in panic disorder: a double blind placebo controlled study with fluvoxamine and ritanserin.
    Psychopharmacology, 1990, Volume: 102, Issue:1

    Topics: Adult; beta-Endorphin; Blood Platelets; Double-Blind Method; Fear; Female; Fluvoxamine; Humans; Hydr

1990
The excretion of 5-hydroxyindoleacetic acid in mental patients.
    Progress in brain research, 1965, Volume: 16

    Topics: Clinical Trials as Topic; Humans; Hydroxyindoleacetic Acid; Mental Disorders; Reserpine; Urine

1965

Other Studies

86 other studies available for hydroxyindoleacetic acid and Mental Disorders

ArticleYear
Brain Serotonergic and Noradrenergic Deficiencies in Behavioral Variant Frontotemporal Dementia Compared to Early-Onset Alzheimer's Disease.
    Journal of Alzheimer's disease : JAD, 2016, 06-15, Volume: 53, Issue:3

    Topics: Aged; Alzheimer Disease; Brain; Dopamine; Female; Frontotemporal Dementia; Humans; Hydroxyindoleacet

2016
Loss of MeCP2 in aminergic neurons causes cell-autonomous defects in neurotransmitter synthesis and specific behavioral abnormalities.
    Proceedings of the National Academy of Sciences of the United States of America, 2009, Dec-22, Volume: 106, Issue:51

    Topics: Amines; Animals; Homovanillic Acid; Hydroxyindoleacetic Acid; Mental Disorders; Methyl-CpG-Binding P

2009
[Serotonin (5-hydroxytriptamin, 5HT)].
    Nihon rinsho. Japanese journal of clinical medicine, 2010, Volume: 68 Suppl 7

    Topics: Aging; Carcinoid Tumor; Chromatography, Gas; Dumping Syndrome; Gas Chromatography-Mass Spectrometry;

2010
[5-Hyroxyindol acetic acid (5HIAA)].
    Nihon rinsho. Japanese journal of clinical medicine, 2010, Volume: 68 Suppl 7

    Topics: Adult; Basal Ganglia Diseases; Carcinoid Tumor; Chromatography, High Pressure Liquid; Gas Chromatogr

2010
CSF 5-HIAA and exposure to and expression of interpersonal violence in suicide attempters.
    Journal of affective disorders, 2011, Volume: 132, Issue:1-2

    Topics: Adolescent; Adult; Aged; Aggression; Child; Child Abuse; Comorbidity; Female; Humans; Hydroxyindolea

2011
Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.
    Molecular psychiatry, 2014, Volume: 19, Issue:2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adult; Biogenic Monoamines; Chromosomes, Human, Pair 11; Female

2014
Cigarette smoking, suicidal behavior, and serotonin function in major psychiatric disorders.
    The American journal of psychiatry, 2003, Volume: 160, Issue:4

    Topics: Adolescent; Adult; Aged; Comorbidity; Depressive Disorder; Female; Fenfluramine; Humans; Hydrocortis

2003
Effects of exposure to selective serotonin reuptake inhibitors during pregnancy on serotonergic symptoms in newborns and cord blood monoamine and prolactin concentrations.
    Archives of general psychiatry, 2003, Volume: 60, Issue:7

    Topics: Adult; Depressive Disorder; Female; Fetal Blood; Humans; Hydroxyindoleacetic Acid; Infant, Newborn;

2003
Effect of reserpine in therapeutic dosage on excretion of 5-hydroxyindoleacetic acid.
    British medical journal, 1958, Mar-01, Volume: 1, Issue:5069

    Topics: Biological Transport; Hydroxyindoleacetic Acid; Indoleacetic Acids; Mental Disorders; Reserpine

1958
Urinary excretion of 5-hydroxyindoleacetic acid in psychotic and normal subjects; excretion after parenteral administration of serotonin.
    A.M.A. archives of neurology and psychiatry, 1958, Volume: 80, Issue:1

    Topics: Hydroxyindoleacetic Acid; Indoleacetic Acids; Mental Disorders; Psychotic Disorders; Serotonin

1958
[Determination of 5-hydroxy-indolacetic acid in urine as a valuable clinicochemical method in modern psychiatric clinics].
    Schweizer Archiv fur Neurologie, Neurochirurgie und Psychiatrie = Archives suisses de neurologie, neurochirurgie et de psychiatrie, 1961, Volume: 87

    Topics: Humans; Hydroxyindoleacetic Acid; Mental Disorders; Psychotic Disorders; Serotonin; Tranquilizing Ag

1961
[Differential diagnostic considerations in increased 5-hydroxyindoleacetic acid excretion in the urine].
    Deutsche medizinische Wochenschrift (1946), 1962, May-04, Volume: 87

    Topics: Diet; Hydroxyindoleacetic Acid; Indoleacetic Acids; Mental Disorders; Nutrition Assessment; Nuts; Ps

1962
Biogenic amines metabolism and blood chemistry of psychiatric patients.
    African journal of medicine and medical sciences, 2001, Volume: 30, Issue:4

    Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Case-Control Studies; Dopamine; Epinephrin

2001
Relationship of MAO-A promoter (u-VNTR) and COMT (V158M) gene polymorphisms to CSF monoamine metabolites levels in a psychiatric sample of caucasians: A preliminary report.
    American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2005, Jan-05, Volume: 132B, Issue:1

    Topics: Adolescent; Adult; Aged; Amino Acid Substitution; Catechol O-Methyltransferase; Female; Genotype; Ho

2005
[Psychotomimetic drugs with anticholinergic effects].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1966, Volume: 66, Issue:3

    Topics: Adolescent; Atropine; Benactyzine; Electroconvulsive Therapy; Electroencephalography; Hallucinogens;

1966
Successive measurements of urinary 5-HIAA in mental illness with special reference to diurnal changes and loading test with tetrabenazine.
    Folia psychiatrica et neurologica japonica, 1966, Volume: 20, Issue:3

    Topics: Adolescent; Adult; Aged; Circadian Rhythm; Female; Humans; Hydroxyindoleacetic Acid; Male; Mental Di

1966
The influence of the lying and sitting positions on the gradients of 5-HIAA and HVA in lumbar cerebrospinal fluid.
    Biological psychiatry, 1984, Volume: 19, Issue:11

    Topics: Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Mental Disorders; Phenylacetates; Posture

1984
CSF monoamine metabolites in child and adult psychiatric patients. A developmental perspective.
    Archives of general psychiatry, 1980, Volume: 37, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Autistic Disorder; Bipolar Disorder; Child; Child, Preschool;

1980
Relationships in healthy volunteers between concentrations of monoamine metabolites in cerebrospinal fluid and family history of psychiatric morbidity.
    The British journal of psychiatry : the journal of mental science, 1980, Volume: 136

    Topics: Adolescent; Adult; Cerebrospinal Fluid Proteins; Female; Glycols; Homovanillic Acid; Humans; Hydroxy

1980
Biochemistry of the augmenting-reducing response in visual evoked potentials.
    Neuropsychobiology, 1981, Volume: 7, Issue:1

    Topics: Adult; Aged; Blood Platelets; Dopamine beta-Hydroxylase; Endorphins; Evoked Potentials; Female; Homo

1981
Relationship between estimated premorbid adjustment and CSF homovanillic acid and 5-hydroxyindoleacetic acid levels.
    The American journal of psychiatry, 1981, Volume: 138, Issue:4

    Topics: Adolescent; Adult; Affective Disorders, Psychotic; Aged; Female; Homovanillic Acid; Humans; Hydroxyi

1981
Gradients of monoamine metabolites and cortisol in cerebrospinal fluid of psychiatric patients and healthy controls.
    Psychiatry research, 1982, Volume: 6, Issue:1

    Topics: Body Height; Depressive Disorder; Glycols; Homovanillic Acid; Humans; Hydrocortisone; Hydroxyindolea

1982
Relationships in healthy volunteers between secretion of monoamine metabolites in urine, and family history of psychiatric morbidity.
    Biological psychiatry, 1982, Volume: 17, Issue:12

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adolescent; Adult; Female; Homovanillic Acid; Humans; Hydroxyindolea

1982
Acid metabolites and precursor amino acids of 5-hydroxytryptamine and dopamine in affective and other psychiatric disorders.
    Psychiatria clinica, 1983, Volume: 16, Issue:1

    Topics: Adjustment Disorders; Adult; Aged; Amino Acids; Bipolar Disorder; Depressive Disorder; Dopamine; Fem

1983
Amine metabolites and neuroendocrine responses related to depression and suicide.
    Journal of affective disorders, 1983, Volume: 5, Issue:3

    Topics: Alcoholism; Depression; Depressive Disorder; Dexamethasone; Female; Homovanillic Acid; Humans; Hydro

1983
CSF 5-HIAA and family history of psychiatric disorder.
    The American journal of psychiatry, 1983, Volume: 140, Issue:9

    Topics: Child, Preschool; Depressive Disorder; Enuresis; Humans; Hydroxyindoleacetic Acid; Mental Disorders

1983
CSF 5-hydroxyindoleacetic acid levels in suicidal schizophrenic patients.
    The American journal of psychiatry, 1984, Volume: 141, Issue:4

    Topics: Adult; Aggression; Female; Humans; Hydroxyindoleacetic Acid; Male; Mental Disorders; Schizophrenia;

1984
Biochemical markers in suicidal patients. Investigations with cerebrospinal fluid amine metabolites and neuroendocrine tests.
    Journal of affective disorders, 1984, Volume: 6, Issue:3-4

    Topics: Adult; Aged; Dexamethasone; Female; Homovanillic Acid; Humans; Hydrocortisone; Hydroxyindoleacetic A

1984
An association between low levels of 5-HIAA and HVA in cerebrospinal fluid and early mortality in a diagnostically mixed psychiatric sample.
    The British journal of psychiatry : the journal of mental science, 1993, Volume: 163

    Topics: Adult; Aged; Cause of Death; Depressive Disorder; Follow-Up Studies; Homovanillic Acid; Hospital Rec

1993
Cholesterol and serotonin: seeking a possible link between blood cholesterol and CSF 5-HIAA.
    Biological psychiatry, 1994, Jun-15, Volume: 35, Issue:12

    Topics: Adult; Cholesterol; Humans; Hydroxyindoleacetic Acid; Male; Mental Disorders; Middle Aged; Retrospec

1994
Elevated cerebrospinal fluid levels of oxytocin in obsessive-compulsive disorder. Comparison with Tourette's syndrome and healthy controls.
    Archives of general psychiatry, 1994, Volume: 51, Issue:10

    Topics: Adolescent; Adult; Age of Onset; Arginine Vasopressin; Biogenic Amines; Comorbidity; Dynorphins; Fam

1994
Antemortem measurements of neurotransmission: possible implications for pharmacotherapy of Alzheimer's disease and depression.
    Journal of neurology, neurosurgery, and psychiatry, 1993, Volume: 56, Issue:1

    Topics: Adult; Alzheimer Disease; Antidepressive Agents; Antipsychotic Agents; Cerebral Ventricles; Female;

1993
Concentration gradients for monoamine metabolites in lumbar cerebrospinal fluid.
    Journal of neural transmission. Parkinson's disease and dementia section, 1993, Volume: 5, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biogenic Monoamines; Chromatography, High Pressure Liqui

1993
Paternal and maternal genetic and environmental contributions to cerebrospinal fluid monoamine metabolites in rhesus monkeys (Macaca mulatta).
    Archives of general psychiatry, 1993, Volume: 50, Issue:8

    Topics: Animals; Fathers; Female; Genetic Markers; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Like

1993
Are monoamine metabolites in cerebrospinal fluid worth measuring?
    Archives of general psychiatry, 1993, Volume: 50, Issue:8

    Topics: Animals; Brain; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Mental Disorders; Met

1993
A longitudinal study of the relationships between psychometric test scores, offence history and the plasma concentrations of phenylacetic and 5-hydroxyindoleacetic acids in seven inmates of a prison for the psychiatrically disturbed.
    Progress in neuro-psychopharmacology & biological psychiatry, 1993, Volume: 17, Issue:4

    Topics: Adult; Aggression; Anger; Anxiety; Crime; Depression; Hostility; Humans; Hydroxyindoleacetic Acid; M

1993
Early-onset alcoholics have lower cerebrospinal fluid 5-hydroxyindoleacetic acid levels than late-onset alcoholics.
    Archives of general psychiatry, 1996, Volume: 53, Issue:3

    Topics: Adult; Age of Onset; Alcohol Drinking; Alcoholism; Comorbidity; Family; Female; Homovanillic Acid; H

1996
A prospective follow-up study of alcoholic violent offenders and fire setters.
    Archives of general psychiatry, 1996, Volume: 53, Issue:6

    Topics: Adult; Alcoholism; Cholesterol; Comorbidity; Criminal Law; Family; Finland; Firesetting Behavior; Fo

1996
Dopamine-related genes and their relationships to monoamine metabolites in CSF.
    Biological psychiatry, 1996, Nov-15, Volume: 40, Issue:10

    Topics: Adult; Biogenic Monoamines; Cerebrospinal Fluid; Dopamine; Female; Genotype; Homovanillic Acid; Huma

1996
ECT in Parkinson's disease. Changes in motor symptoms, monoamine metabolites and neuropeptides.
    Journal of neural transmission. Parkinson's disease and dementia section, 1995, Volume: 10, Issue:2-3

    Topics: Aged; Aged, 80 and over; Biogenic Monoamines; Electroconvulsive Therapy; Female; Homovanillic Acid;

1995
Cerebrospinal fluid vasopressin levels: correlates with aggression and serotonin function in personality-disordered subjects.
    Archives of general psychiatry, 1998, Volume: 55, Issue:8

    Topics: Adult; Aggression; Arginine Vasopressin; Female; Fenfluramine; Humans; Hydroxyindoleacetic Acid; Imp

1998
Alterations in serotonin activity and psychiatric symptoms after recovery from bulimia nervosa.
    Archives of general psychiatry, 1998, Volume: 55, Issue:10

    Topics: Adolescent; Adult; Affect; Body Weight; Brain Chemistry; Bulimia; Feeding Behavior; Female; Follow-U

1998
[Biological approach to adolescent suicide].
    La Revue du praticien, 1998, Sep-01, Volume: 48, Issue:13

    Topics: Adolescent; Adolescent Behavior; Adult; Age Factors; Animals; Biomarkers; Child; Genetic Markers; Ha

1998
Variations in CSF monoamine metabolites according to the season of birth.
    Neuropsychobiology, 1999, Volume: 39, Issue:2

    Topics: Adult; Aged; Analysis of Variance; Biogenic Monoamines; Cohort Effect; Cross-Sectional Studies; Dise

1999
HTR2C Cys23Ser polymorphism in relation to CSF monoamine metabolite concentrations and DSM-III-R psychiatric diagnoses.
    Biological psychiatry, 1999, Sep-15, Volume: 46, Issue:6

    Topics: Alcoholism; Biogenic Monoamines; Brain; Dopamine; Genes; Genotype; Homovanillic Acid; Humans; Hydrox

1999
Reduced cerebrospinal HVA concentrations and HVA/5-HIAA ratios in suicide attempters. Monoamine metabolites in 120 suicide attempters and 47 controls.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1999, Volume: 9, Issue:5

    Topics: Adolescent; Adult; Age Factors; Aged; Biomarkers; Female; Homovanillic Acid; Humans; Hydroxyindoleac

1999
Association of aggressive behavior with altered serotonergic function in patients who are not suicidal.
    The American journal of psychiatry, 2000, Volume: 157, Issue:4

    Topics: Adult; Aggression; Brief Psychiatric Rating Scale; Female; Humans; Hydroxyindoleacetic Acid; Impulsi

2000
Suicide attempts and impulse control disorder are related to low cerebrospinal fluid 5-HIAA in mentally disordered violent offenders.
    Acta psychiatrica Scandinavica, 2000, Volume: 101, Issue:5

    Topics: Adult; Disruptive, Impulse Control, and Conduct Disorders; Homicide; Homovanillic Acid; Humans; Hydr

2000
Biogenic amine turnover and serum cholesterol in suicide attempt.
    European archives of psychiatry and clinical neuroscience, 2002, Volume: 252, Issue:1

    Topics: Adult; Biogenic Monoamines; Cholesterol; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid

2002
Visual averaged evoked responses in psychiatric patients. Relationship to levels of 5-hydroxy-indoleacetic acid, homovanilic acid and tryptophan in cerebrospinal fluid.
    Journal of psychiatric research, 1979, Volume: 15, Issue:3

    Topics: Adult; Age Factors; Aged; Brain; Evoked Potentials; Female; Homovanillic Acid; Humans; Hydroxyindole

1979
Interactions between central monoaminergic systems: dopamine-serotonin.
    Journal of neurology, neurosurgery, and psychiatry, 1979, Volume: 42, Issue:12

    Topics: Adolescent; Adult; Aged; Bipolar Disorder; Depression; Dopamine; Dyskinesia, Drug-Induced; Female; H

1979
A menstruation-linked periodic hypersomnia. Kleine-Levin syndrome or new clinical entity?
    Neurology, 1975, Volume: 25, Issue:5

    Topics: Adolescent; Disorders of Excessive Somnolence; Electroencephalography; Estrogens, Conjugated (USP);

1975
Cerebrospinal fluid cyclic AMP and acid monoamine metabolites following probenecid: studies in psychiatric patients.
    Psychopharmacology, 1979, Mar-29, Volume: 62, Issue:1

    Topics: Adolescent; Adult; Aged; Biogenic Amines; Chlorpromazine; Cyclic AMP; Depression; Female; Homovanill

1979
Assessment of cerebrospinal monoamine metabolites in children using the probenecid method.
    The Israel annals of psychiatry and related disciplines, 1977,Spring, Volume: 15, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Ma

1977
Dopamine and serotonin metabolism in neuropsychiatrically disturbed children. CSF homovanillic acid and 5-hydroxyindoleacetic acid.
    Archives of general psychiatry, 1977, Volume: 34, Issue:5

    Topics: Adolescent; Age Factors; Aphasia; Attention Deficit Disorder with Hyperactivity; Autistic Disorder;

1977
CSF amine metabolites, clinical symptoms, and body movement in psychiatric patients.
    Biological psychiatry, 1976, Volume: 11, Issue:4

    Topics: Adult; Anger; Anxiety; Arousal; Brain; Depression; Female; Homovanillic Acid; Humans; Hydroxyindolea

1976
Importance of dopamine metabolism for clinical effects and side effects of neuroleptics.
    The American journal of psychiatry, 1976, Volume: 133, Issue:10

    Topics: Adult; Aged; Antiparkinson Agents; Basal Ganglia Diseases; Chlorpromazine; Dopamine; Dopamine Antago

1976
Precursors and metabolites of 5-hydroxytryptamine and dopamine in the ventricular cerebrospinal fluid of psychiatric patients.
    Psychological medicine, 1976, Volume: 6, Issue:3

    Topics: Adult; Aged; Anxiety Disorders; Brain Diseases; Cerebral Ventricles; Depression; Female; Homovanilli

1976
Neurophysiological measures related to levels of 5-hydroxyindoleacetic acid, homovanillic acid and tryptophan in cerebrospinal fluid of psychiatric patients.
    Neuropsychobiology, 1976, Volume: 2, Issue:1

    Topics: Adult; Aged; Electroencephalography; Evoked Potentials; Female; Homovanillic Acid; Humans; Hydroxyin

1976
Central noradrenergic function in man: vanillylmandelic acid in CSF.
    Brain research, 1975, Dec-05, Volume: 99, Issue:2

    Topics: Acute Disease; Affective Symptoms; Bipolar Disorder; Depression; Homovanillic Acid; Humans; Hydroxyi

1975
Relationship between central and peripheral serotonin indexes in depressed and suicidal psychiatric inpatients.
    Archives of general psychiatry, 1992, Volume: 49, Issue:6

    Topics: Adult; Blood Platelets; Depressive Disorder; Female; Fenfluramine; Hospitalization; Humans; Hydroxyi

1992
A comment on the selection of 'healthy controls' for psychiatric experiments.
    Archives of general psychiatry, 1990, Volume: 47, Issue:8

    Topics: Depressive Disorder; Humans; Hydroxyindoleacetic Acid; Mental Disorders; Models, Statistical; Resear

1990
The effect of age, sex, weight and height on the plasma concentrations in healthy subjects of the acidic metabolites of some biogenic monoamines involved in psychiatric and neurological disorders.
    Progress in neuro-psychopharmacology & biological psychiatry, 1991, Volume: 15, Issue:4

    Topics: Adult; Aged; Aging; Biogenic Monoamines; Body Height; Body Weight; Female; Homovanillic Acid; Humans

1991
Brain ventricular size and CSF monoamine metabolites in an adolescent inpatient population.
    Psychiatry research, 1985, Volume: 16, Issue:2

    Topics: Adolescent; Adult; Age Factors; Cerebral Ventricles; Child; Dilatation, Pathologic; Female; Homovani

1985
Skin conductance habituation and cerebrospinal fluid 5-hydroxyindoleacetic acid in suicidal patients.
    Archives of general psychiatry, 1986, Volume: 43, Issue:6

    Topics: Adult; Aged; Animals; Depressive Disorder; Female; Galvanic Skin Response; Guinea Pigs; Habituation,

1986
5-HT, a neurotransmitter for all seasons?
    Biological psychiatry, 1987, Volume: 22, Issue:1

    Topics: Behavior; Humans; Hydroxyindoleacetic Acid; Mental Disorders; Serotonin

1987
Generalizable treatment strategies for suicidal behavior.
    Annals of the New York Academy of Sciences, 1986, Volume: 487

    Topics: Adolescent; Adult; Female; Humans; Hydroxyindoleacetic Acid; Life Change Events; Male; Mental Disord

1986
Psychiatric symptoms and cerebrospinal fluid monoamine metabolites in primary hyperparathyroidism.
    Biological psychiatry, 1988, Jan-15, Volume: 23, Issue:2

    Topics: Aged; Calcium; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Hyperparathyroi

1988
N-acetylation and serotonergic measures in a group of psychiatric patients.
    Acta psychiatrica Scandinavica, 1988, Volume: 77, Issue:6

    Topics: Acetylation; Adult; Bipolar Disorder; Depressive Disorder; Female; Humans; Hydroxyindoleacetic Acid;

1988
Seasonal changes of CSF monoamine metabolites in psychiatric patients: what is the source?
    Psychiatry research, 1988, Volume: 25, Issue:3

    Topics: Bipolar Disorder; Depressive Disorder; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Mental D

1988
5-H.T. metabolism in psychiatric syndromes.
    Lancet (London, England), 1970, Nov-14, Volume: 2, Issue:7681

    Topics: Humans; Hydroxyindoleacetic Acid; Mental Disorders; Serotonin

1970
Modified amine hypothesis for the aetiology of affective illness.
    Lancet (London, England), 1972, Sep-16, Volume: 2, Issue:7777

    Topics: Affective Symptoms; Amines; Animals; Antidepressive Agents; Binding Sites; Biogenic Amines; Bipolar

1972
5-hydroxyindole compounds in the cerebrospinal fluid of patients with psychiatric or neurological diseases.
    Lancet (London, England), 1966, Nov-12, Volume: 2, Issue:7472

    Topics: Alcoholism; Bipolar Disorder; Central Nervous System Diseases; Humans; Hydroxyindoleacetic Acid; Imi

1966
Parkinsonism-dementia of Guam: treatment with L-dopa.
    Neurology, 1971, Volume: 21, Issue:12

    Topics: Adult; Dementia; Dihydroxyphenylalanine; Drug Eruptions; Female; Humans; Hydroxyindoleacetic Acid; H

1971
Amine metabolites in the cerbrospinal fluid in Huntington's chorea.
    Journal of neurology, neurosurgery, and psychiatry, 1972, Volume: 35, Issue:4

    Topics: Adult; Aged; Dopamine; Female; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Male; Mental Di

1972
Some remarks concerning the possible role of brain monoamines (dopamine, noradrenaline, serotonin) in mental disorders.
    Journal of psychiatric research, 1974, Volume: 11

    Topics: Brain; Caudate Nucleus; Depression; Dopamine; Globus Pallidus; Humans; Huntington Disease; Hydroxyin

1974
Visual averaged evoked responses (aer) and monoamine metabolites in cerebrospinal fluid (csf).
    Acta psychiatrica Scandinavica. Supplementum, 1974, Volume: 255

    Topics: Adult; Age Factors; Aged; Brain; Electric Stimulation; Evoked Potentials; Female; Functional Lateral

1974
Effect of probenecid on free 3-methoxy-4-hydroxyphenylethylene glycol (MHPG) and its sulphate in human cerebrospinal fluid.
    Neuropharmacology, 1973, Volume: 12, Issue:4

    Topics: Biological Transport, Active; Brain; Catechols; Chromatography, Gas; Fluorometry; Glycols; Humans; H

1973
Tryptophan malabsorption in levodopa-treated parkinsonian patients. Effect of tryptophan on mental disturbances.
    Acta medica Scandinavica, 1973, Volume: 194, Issue:3

    Topics: Aged; Brain; Dementia; Depression, Chemical; Dihydroxyphenylalanine; Female; Humans; Hydroxyindoleac

1973
Carcinoid and psychiatric symptoms.
    Southern medical journal, 1973, Volume: 66, Issue:7

    Topics: Adult; Affective Symptoms; Aged; Anxiety; Brain; Carcinoid Tumor; Cyclophosphamide; Depression; Huma

1973
5-Hydroxyindoleacetic acid in cerebrospinal fluid.
    Acta medica Academiae Scientiarum Hungaricae, 1973, Volume: 30, Issue:3

    Topics: Adult; Age Factors; Brain Diseases; Brain Stem; Depression; Epilepsy; Humans; Hydroxyindoleacetic Ac

1973
Clinical measurements of central dopamine and 5-hydroxytryptamine metabolism: reliability and interpretation of cerebrospinal fluid acid monoamine metabolite measures.
    Neuropharmacology, 1972, Volume: 11, Issue:1

    Topics: Age Factors; Central Nervous System; Chemistry, Clinical; Dopamine; Fluorometry; Humans; Hydroxyindo

1972
Parkinsonism-dementia and amyotrophic lateral sclerosis of Guam. Effect of probenecid on monoamine catabolite levels in cerebrospinal fluid.
    Archives of neurology, 1971, Volume: 25, Issue:1

    Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Dihydroxyphenylalanine; Dopamine; Female; Humans; Hydrox

1971
Initial mental disorders in carcinoma of pancreas and stomach.
    Acta psychiatrica Scandinavica. Supplementum, 1971, Volume: 221

    Topics: Adult; Aged; Anxiety; Depression; Female; Humans; Hydroxyindoleacetic Acid; Male; Mental Disorders;

1971
[Excretion of 5-hydroxyindoleacetic acid and vanilmandelic acid in patients with glaucoma].
    Ceskoslovenska oftalmologie, 1967, Volume: 23, Issue:3

    Topics: Benzoates; Catecholamines; Female; Glaucoma; Humans; Hydroxyindoleacetic Acid; Male; Mandelic Acids;

1967
Psychopathology and 5-hydroxyindoleacetic acid excretion.
    Journal of psychiatric research, 1965, Volume: 3, Issue:2

    Topics: Humans; Hydroxyindoleacetic Acid; Mental Disorders; Urine

1965