hydroxyindoleacetic acid has been researched along with Lewy Body Disease in 2 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
Lewy Body Disease: A neurodegenerative disease characterized by dementia, mild parkinsonism, and fluctuations in attention and alertness. The neuropsychiatric manifestations tend to precede the onset of bradykinesia, MUSCLE RIGIDITY, and other extrapyramidal signs. DELUSIONS and visual HALLUCINATIONS are relatively frequent in this condition. Histologic examination reveals LEWY BODIES in the CEREBRAL CORTEX and BRAIN STEM. SENILE PLAQUES and other pathologic features characteristic of ALZHEIMER DISEASE may also be present. (From Neurology 1997;48:376-380; Neurology 1996;47:1113-1124)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lewy body disorders, including Parkinson's disease (PD), Parkinson's disease dementia (PDD) and dementia with Lewy bodies (DLB), are characterized by profound central and peripheral monoaminergic dysfunction." | 1.48 | Monoaminergic Markers Across the Cognitive Spectrum of Lewy Body Disease. ( Aerts, T; De Deyn, PP; Fransen, E; Gerritsen, MJ; Spikman, JM; Van Dam, D; van der Zee, S; van Laar, T; Vermeiren, Y, 2018) |
| "Dementia with Lewy bodies (DLB) and Alzheimer's disease (AD) are the two most common causes of dementia." | 1.46 | Homovanillic acid and 5-hydroxyindole acetic acid as biomarkers for dementia with Lewy bodies and coincident Alzheimer's disease: An autopsy-confirmed study. ( Hatsuta, H; Kanemaru, K; Komiya, T; Morimoto, S; Murayama, S; Nakano, Y; Nishina, Y; Saito, Y; Sengoku, R; Sumikura, H; Takao, M; Uchino, A, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| van der Zee, S | 1 |
| Vermeiren, Y | 1 |
| Fransen, E | 1 |
| Van Dam, D | 1 |
| Aerts, T | 1 |
| Gerritsen, MJ | 1 |
| Spikman, JM | 1 |
| van Laar, T | 1 |
| De Deyn, PP | 1 |
| Morimoto, S | 1 |
| Takao, M | 1 |
| Hatsuta, H | 1 |
| Nishina, Y | 1 |
| Komiya, T | 1 |
| Sengoku, R | 1 |
| Nakano, Y | 1 |
| Uchino, A | 1 |
| Sumikura, H | 1 |
| Saito, Y | 1 |
| Kanemaru, K | 1 |
| Murayama, S | 1 |
2 other studies available for hydroxyindoleacetic acid and Lewy Body Disease
| Article | Year |
|---|---|
Monoaminergic Markers Across the Cognitive Spectrum of Lewy Body Disease.
Topics: Aged; Biogenic Monoamines; Biomarkers; Cognition Disorders; Cognitive Dysfunction; Diagnosis, Differ | 2018 |
Homovanillic acid and 5-hydroxyindole acetic acid as biomarkers for dementia with Lewy bodies and coincident Alzheimer's disease: An autopsy-confirmed study.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Autopsy; Biomarkers; Diagn | 2017 |