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hydroxyindoleacetic acid and Leukopenia

hydroxyindoleacetic acid has been researched along with Leukopenia in 3 studies

(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.

Leukopenia: A decrease in the number of LEUKOCYTES in a blood sample below the normal range (LEUKOCYTE COUNT less than 4000).

Research Excerpts

ExcerptRelevanceReference
"Sixteen patients with metastatic carcinoid tumor and the malignant carcinoid syndrome were treated with combined cyclophosphamide and methotrexate therapy in a regimen previously described as highly effective."7.67Evaluation of combined cyclophosphamide and methotrexate therapy in the treatment of metastatic carcinoid tumor and the malignant carcinoid syndrome. ( Moertel, CG; O'Connell, MJ; Reitemeier, RJ; Rubin, J, 1984)
"Sixteen patients with metastatic carcinoid tumor and the malignant carcinoid syndrome were treated with combined cyclophosphamide and methotrexate therapy in a regimen previously described as highly effective."3.67Evaluation of combined cyclophosphamide and methotrexate therapy in the treatment of metastatic carcinoid tumor and the malignant carcinoid syndrome. ( Moertel, CG; O'Connell, MJ; Reitemeier, RJ; Rubin, J, 1984)
"The predominant histotype was carcinoid, although a few cases had malignant islet cell tumors, medullary thyroid carcinoma, Merkel cell carcinoma, or other neuroendocrine tumors."2.67Treatment of metastatic carcinoids and other neuroendocrine tumors with recombinant interferon-alpha-2a. A study by the Italian Trials in Medical Oncology Group. ( Bajetta, E; Bochicchio, AM; Buzzoni, R; Castellani, R; Celio, L; Di Bartolomeo, M; Di Leo, A; Dogliotti, L; Pilotti, S; Zilembo, N, 1993)
"Eight patients with metastatic carcinoid tumor, seven of whom had symptoms of the carcinoid syndrome, were treated with either human leukocyte interferon (seven patients) or recombinant alpha-interferon (IFN alpha-2b) (one patient) at doses of 4."2.67Is the treatment of metastatic carcinoid tumor with interferon not as successful as suggested? ( Järvinen, H; Pelkonen, R; Salmela, P; Sane, T; Sjöblom, SM; Välimäki, M, 1991)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Moertel, CG1
O'Connell, MJ1
Reitemeier, RJ1
Rubin, J1
Bajetta, E1
Zilembo, N1
Di Bartolomeo, M1
Di Leo, A1
Pilotti, S1
Bochicchio, AM1
Castellani, R1
Buzzoni, R1
Celio, L1
Dogliotti, L1
Välimäki, M1
Järvinen, H1
Salmela, P1
Sane, T1
Sjöblom, SM1
Pelkonen, R1

Trials

2 trials available for hydroxyindoleacetic acid and Leukopenia

ArticleYear
Treatment of metastatic carcinoids and other neuroendocrine tumors with recombinant interferon-alpha-2a. A study by the Italian Trials in Medical Oncology Group.
    Cancer, 1993, Nov-15, Volume: 72, Issue:10

    Topics: Adult; Aged; Biomarkers, Tumor; Carcinoid Tumor; Drug Administration Schedule; Female; Fever; Humans

1993
Is the treatment of metastatic carcinoid tumor with interferon not as successful as suggested?
    Cancer, 1991, Feb-01, Volume: 67, Issue:3

    Topics: Adult; Aged; Carcinoid Tumor; Female; Humans; Hydroxyindoleacetic Acid; Interferon alpha-2; Interfer

1991

Other Studies

1 other study available for hydroxyindoleacetic acid and Leukopenia

ArticleYear
Evaluation of combined cyclophosphamide and methotrexate therapy in the treatment of metastatic carcinoid tumor and the malignant carcinoid syndrome.
    Cancer treatment reports, 1984, Volume: 68, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoid Tumor; Cyclophosphamide; Drug

1984