hydroxyindoleacetic acid has been researched along with Leukopenia in 3 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
Leukopenia: A decrease in the number of LEUKOCYTES in a blood sample below the normal range (LEUKOCYTE COUNT less than 4000).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sixteen patients with metastatic carcinoid tumor and the malignant carcinoid syndrome were treated with combined cyclophosphamide and methotrexate therapy in a regimen previously described as highly effective." | 7.67 | Evaluation of combined cyclophosphamide and methotrexate therapy in the treatment of metastatic carcinoid tumor and the malignant carcinoid syndrome. ( Moertel, CG; O'Connell, MJ; Reitemeier, RJ; Rubin, J, 1984) |
| "Sixteen patients with metastatic carcinoid tumor and the malignant carcinoid syndrome were treated with combined cyclophosphamide and methotrexate therapy in a regimen previously described as highly effective." | 3.67 | Evaluation of combined cyclophosphamide and methotrexate therapy in the treatment of metastatic carcinoid tumor and the malignant carcinoid syndrome. ( Moertel, CG; O'Connell, MJ; Reitemeier, RJ; Rubin, J, 1984) |
| "The predominant histotype was carcinoid, although a few cases had malignant islet cell tumors, medullary thyroid carcinoma, Merkel cell carcinoma, or other neuroendocrine tumors." | 2.67 | Treatment of metastatic carcinoids and other neuroendocrine tumors with recombinant interferon-alpha-2a. A study by the Italian Trials in Medical Oncology Group. ( Bajetta, E; Bochicchio, AM; Buzzoni, R; Castellani, R; Celio, L; Di Bartolomeo, M; Di Leo, A; Dogliotti, L; Pilotti, S; Zilembo, N, 1993) |
| "Eight patients with metastatic carcinoid tumor, seven of whom had symptoms of the carcinoid syndrome, were treated with either human leukocyte interferon (seven patients) or recombinant alpha-interferon (IFN alpha-2b) (one patient) at doses of 4." | 2.67 | Is the treatment of metastatic carcinoid tumor with interferon not as successful as suggested? ( Järvinen, H; Pelkonen, R; Salmela, P; Sane, T; Sjöblom, SM; Välimäki, M, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moertel, CG | 1 |
| O'Connell, MJ | 1 |
| Reitemeier, RJ | 1 |
| Rubin, J | 1 |
| Bajetta, E | 1 |
| Zilembo, N | 1 |
| Di Bartolomeo, M | 1 |
| Di Leo, A | 1 |
| Pilotti, S | 1 |
| Bochicchio, AM | 1 |
| Castellani, R | 1 |
| Buzzoni, R | 1 |
| Celio, L | 1 |
| Dogliotti, L | 1 |
| Välimäki, M | 1 |
| Järvinen, H | 1 |
| Salmela, P | 1 |
| Sane, T | 1 |
| Sjöblom, SM | 1 |
| Pelkonen, R | 1 |
2 trials available for hydroxyindoleacetic acid and Leukopenia
| Article | Year |
|---|---|
Treatment of metastatic carcinoids and other neuroendocrine tumors with recombinant interferon-alpha-2a. A study by the Italian Trials in Medical Oncology Group.
Topics: Adult; Aged; Biomarkers, Tumor; Carcinoid Tumor; Drug Administration Schedule; Female; Fever; Humans | 1993 |
Is the treatment of metastatic carcinoid tumor with interferon not as successful as suggested?
Topics: Adult; Aged; Carcinoid Tumor; Female; Humans; Hydroxyindoleacetic Acid; Interferon alpha-2; Interfer | 1991 |
1 other study available for hydroxyindoleacetic acid and Leukopenia
| Article | Year |
|---|---|
Evaluation of combined cyclophosphamide and methotrexate therapy in the treatment of metastatic carcinoid tumor and the malignant carcinoid syndrome.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoid Tumor; Cyclophosphamide; Drug | 1984 |