hydroxyindoleacetic acid has been researched along with Lesion of Sciatic Nerve in 2 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To further establish the neurochemical basis for its supraspinally mediated analgesic action, concentrations of spinal noradrenaline, 4-hydroxy-3-methoxyphenylglycol (MHPG), serotonin (5-HT), 5-hydroxyindoleacetic acid (5-HIAA) and dopamine were measured using high-performance liquid chromatography in a murine neuropathic pain model that was prepared by partial ligation of the sciatic nerve (the Seltzer model)." | 3.74 | Neurochemical evidence that supraspinally administered gabapentin activates the descending noradrenergic system after peripheral nerve injury. ( Honda, M; Ono, H; Takasu, K; Takeuchi, Y; Tanabe, M, 2007) |
| "5-HTT-/- mice did not develop thermal hyperalgesia, but showed bilateral mechanical allodynia after the nerve injury." | 1.32 | Absence of thermal hyperalgesia in serotonin transporter-deficient mice. ( Gerlach, M; Heinemann, T; Lesch, KP; Mössner, R; Murphy, DL; Riederer, P; Sommer, C; Vogel, C, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vogel, C | 1 |
| Mössner, R | 1 |
| Gerlach, M | 1 |
| Heinemann, T | 1 |
| Murphy, DL | 1 |
| Riederer, P | 1 |
| Lesch, KP | 1 |
| Sommer, C | 1 |
| Takeuchi, Y | 1 |
| Takasu, K | 1 |
| Honda, M | 1 |
| Ono, H | 1 |
| Tanabe, M | 1 |
2 other studies available for hydroxyindoleacetic acid and Lesion of Sciatic Nerve
| Article | Year |
|---|---|
Absence of thermal hyperalgesia in serotonin transporter-deficient mice.
Topics: Adrenal Glands; Animals; Behavior, Animal; Carrier Proteins; Disease Models, Animal; Hindlimb; Hot T | 2003 |
Neurochemical evidence that supraspinally administered gabapentin activates the descending noradrenergic system after peripheral nerve injury.
Topics: Amines; Analgesics; Animals; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gaba | 2007 |