hydroxyindoleacetic acid has been researched along with Island Cell Tumor in 10 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with undifferentiated carcinomas, originating in typical neuroendocrine tumor sites (small and large bowel, pancreas, and stomach) or of unknown origin, who have consistent histologic findings by light microscopy should be evaluated for this possibility with appropriate immune staining or electron microscopy." | 5.28 | Treatment of neuroendocrine carcinomas with combined etoposide and cisplatin. Evidence of major therapeutic activity in the anaplastic variants of these neoplasms. ( Kvols, LK; Moertel, CG; O'Connell, MJ; Rubin, J, 1991) |
| " Carcinoid tumors with liver metastases, especially those of midgut origin, produce serotonin via the precursors tryptophan and 5-hydroxytryptophan (5-HTP) and this overproduction contributes to the clinical symptoms of the carcinoid syndrome." | 5.07 | Positron emission tomography (PET) in neuroendocrine gastrointestinal tumors. ( Ahlström, H; Bergström, M; Eriksson, B; Långström, B; Lilja, A; Oberg, K, 1993) |
| "Malignant carcinoid tumours, islet cell tumours and medullary carcinomas of the thyroid are tumours with similar clinical features." | 2.67 | Recombinant interferon alpha-2b in patients with metastatic apudomas: effect on tumours and tumour markers. ( Biesma, B; de Bruijn, HW; de Vries, EG; Kema, IP; Mulder, NH; Postmus, PE; Sleijfer, DT; Verschueren, RC; Willemse, PH, 1992) |
| "Patients with undifferentiated carcinomas, originating in typical neuroendocrine tumor sites (small and large bowel, pancreas, and stomach) or of unknown origin, who have consistent histologic findings by light microscopy should be evaluated for this possibility with appropriate immune staining or electron microscopy." | 1.28 | Treatment of neuroendocrine carcinomas with combined etoposide and cisplatin. Evidence of major therapeutic activity in the anaplastic variants of these neoplasms. ( Kvols, LK; Moertel, CG; O'Connell, MJ; Rubin, J, 1991) |
| "Etoposide has activity in APUD tumors; further studies with this agent are indicated." | 1.27 | Phase II trial of etoposide in APUD tumors. ( Cheng, E; Fiore, J; Heelan, R; Kelsen, D; Magill, G, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (70.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| VAN DER VEER, JS | 1 |
| CHOUFOER, JC | 1 |
| QUERIDO, A | 1 |
| VAN DER HEUL, RO | 1 |
| HOLLANDER, CF | 1 |
| VAN RIJSSEL, T | 1 |
| SAYLE, BA | 1 |
| LANG, PA | 1 |
| GREEN, WO | 1 |
| BOSWORTH, WC | 1 |
| GREGORY, R | 1 |
| Eriksson, B | 1 |
| Bergström, M | 1 |
| Lilja, A | 1 |
| Ahlström, H | 1 |
| Långström, B | 1 |
| Oberg, K | 1 |
| Biesma, B | 1 |
| Willemse, PH | 1 |
| Mulder, NH | 1 |
| Verschueren, RC | 1 |
| Kema, IP | 1 |
| de Bruijn, HW | 1 |
| Postmus, PE | 1 |
| Sleijfer, DT | 1 |
| de Vries, EG | 1 |
| Moertel, CG | 1 |
| Kvols, LK | 1 |
| O'Connell, MJ | 2 |
| Rubin, J | 1 |
| Kelsen, D | 1 |
| Fiore, J | 1 |
| Heelan, R | 1 |
| Cheng, E | 1 |
| Magill, G | 1 |
| Weichert, R | 1 |
| Reed, R | 1 |
| Creech, O | 1 |
| Patchefsky, AS | 1 |
| Solit, R | 1 |
| Phillips, LD | 1 |
| Craddock, M | 1 |
| Harrer, MV | 1 |
| Cohn, HE | 1 |
| Kowlessar, OD | 1 |
| Modlinger, RS | 1 |
| Nicolis, GL | 1 |
| Pertsemlidis, D | 1 |
| Gabrilove, JL | 1 |
| Schein, PS | 1 |
| Blom, J | 1 |
| Hubbard, S | 1 |
| Magrath, IT | 1 |
| Bergevin, P | 1 |
| Wiernik, PH | 1 |
| Ziegler, JL | 1 |
| DeVita, VT | 1 |
3 trials available for hydroxyindoleacetic acid and Island Cell Tumor
| Article | Year |
|---|---|
Positron emission tomography (PET) in neuroendocrine gastrointestinal tumors.
Topics: 5-Hydroxytryptophan; Adenoma, Islet Cell; Carbon Radioisotopes; Carcinoid Tumor; Female; Gastrointes | 1993 |
Recombinant interferon alpha-2b in patients with metastatic apudomas: effect on tumours and tumour markers.
Topics: Adenoma, Islet Cell; Adult; Aged; Apudoma; Biomarkers, Tumor; Blood Platelets; Carcinoid Tumor; Cate | 1992 |
Clinical antitumor activity and toxicity of streptozotocin (NSC-85998).
Topics: Adenoma, Islet Cell; Blood Cells; Burkitt Lymphoma; Carcinoid Tumor; Carmustine; Clinical Trials as | 1974 |
7 other studies available for hydroxyindoleacetic acid and Island Cell Tumor
| Article | Year |
|---|---|
METASTASISING ISLET-CELL TUMOUR OF THE PANCREAS ASSOCIATED WITH HYPOGLYCAEMIA AND CARCINOID SYNDROME.
Topics: Adenoma, Islet Cell; Cortisone; Ergot Alkaloids; Humans; Hydroxyindoleacetic Acid; Hypoglycemia; Ind | 1964 |
CUSHING'S SYNDROME DUE TO ISLET CELL CARCINOMA OF THE PANCREAS. REPORT OF TWO CASES: ONE WITH ELEVATED 5-HYDROXYINDOLE ACETIC ACID AND COMPLICATED BY ASPERGILLOSIS.
Topics: Acetates; Adenoma, Islet Cell; Adolescent; Adrenal Cortex Hormones; Adrenalectomy; Aspergillosis; Ca | 1965 |
Treatment of neuroendocrine carcinomas with combined etoposide and cisplatin. Evidence of major therapeutic activity in the anaplastic variants of these neoplasms.
Topics: Adenoma, Islet Cell; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoid Tumor; C | 1991 |
Phase II trial of etoposide in APUD tumors.
Topics: Adenoma, Islet Cell; Adult; Aged; Calcitonin; Carcinoembryonic Antigen; Carcinoid Tumor; Drug Evalua | 1987 |
Carcinoid-islet cell tumors of the duodenum.
Topics: Adenoma, Islet Cell; Adult; Carcinoid Tumor; Duodenal Neoplasms; Duodenal Ulcer; Female; Gastrectomy | 1967 |
Hydroxyindole-producing tumors of the pancreas. Carcinoid-islet cell tumor and oat cell carcinoma.
Topics: Adenoma, Islet Cell; Angiography; Biopsy; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Cyanosis; | 1972 |
Cushing's syndrome and avascular necrosis of bone associated with carcinoid-islet cell tumor of the pancreas.
Topics: Adenoma, Islet Cell; Adrenal Cortex Hormones; Adrenalectomy; Adult; Aged; Bone Diseases; Carcinoid T | 1972 |