hydroxyindoleacetic acid has been researched along with Hypoxia in 36 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Long-term hypoxia induces changes in neuropeptide-Y-like immunoreactivity (NPY-LI) and/or in the content of serotonin (5-HT) and its metabolite 5-hydroxyindoleacetic acid (5-HIAA) at the central level." | 7.70 | Effects of carotid sinus nerve transection on changes in neuropeptide Y and indolamines induced by long-term hypoxia in rats. ( Dalmaz, Y; Denoroy, L; Pequignot, JM; Poncet, L, 1998) |
| "The effects of cinepazide, a vasodilator, on the content, biosynthesis and turnover of noradrenaline (NA), dopamine (DA) and 5-hydroxytryptamine (5-HT) in the rat brain were examined under room air and hypoxia (10% O2, 90% N2)." | 7.67 | The effects of cinepazide on the content, biosynthesis and turnover of noradrenaline, dopamine and 5-hydroxytryptamine in the rat brain under room air and hypoxia. ( Fujiwara, M; Lee, K; Miwa, S, 1986) |
| " Compared with wild-type mice, SM22-5-HTT(+) mice showed depressed hypoxic pulmonary vasoconstriction contrasting with greater severity of hypoxia- or monocrotaline-induced PH." | 3.73 | Transgenic mice overexpressing the 5-hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension. ( Adnot, S; Barlier-Mur, AM; Eddahibi, S; Guignabert, C; Hamon, M; Hanoun, N; Izikki, M; Li, Z; Rodman, D; Tu, LI; Zadigue, P, 2006) |
| "Long-term hypoxia induces changes in neuropeptide-Y-like immunoreactivity (NPY-LI) and/or in the content of serotonin (5-HT) and its metabolite 5-hydroxyindoleacetic acid (5-HIAA) at the central level." | 3.70 | Effects of carotid sinus nerve transection on changes in neuropeptide Y and indolamines induced by long-term hypoxia in rats. ( Dalmaz, Y; Denoroy, L; Pequignot, JM; Poncet, L, 1998) |
| "To determine whether sustained hypoxia alters daily rhythms in brain and pituitary neurotransmitters, the daily variations in vasoactive intestinal peptide-like immunoreactivity (VIP-LI), neuropeptide Y-like immunoreactivity (NPY-LI), serotonin (5-HT), and 5-hydroxyindole-3-acetic acid (5-HIAA) content were determined in discrete brain regions, pineal gland and anterior pituitary of hypoxic (10% O(2); 14 days) and normoxic rats." | 3.70 | Altered daily rhythms of brain and pituitary indolamines and neuropeptides in long-term hypoxic rats. ( Cottet-Emard, JM; Dalmaz, Y; Denoroy, L; Pequignot, JM; Poncet, L, 1999) |
| "The influence of long-term hypoxia (10% O2, 14 days) on in vivo activity of tryptophan hydroxylase and on 5-hydroxytryptamine (5-HT) and 5-hydroxyindoleacetic acid (5-HIAA) concentration in discrete brain regions of rats was assessed." | 3.69 | Activity of tryptophan hydroxylase and content of indolamines in discrete brain regions after a long-term hypoxic exposure in the rat. ( Dalmaz, Y; Denoroy, L; Pequignot, JM; Poncet, L, 1997) |
| "The effects of cinepazide, a vasodilator, on the content, biosynthesis and turnover of noradrenaline (NA), dopamine (DA) and 5-hydroxytryptamine (5-HT) in the rat brain were examined under room air and hypoxia (10% O2, 90% N2)." | 3.67 | The effects of cinepazide on the content, biosynthesis and turnover of noradrenaline, dopamine and 5-hydroxytryptamine in the rat brain under room air and hypoxia. ( Fujiwara, M; Lee, K; Miwa, S, 1986) |
| " Hypoxia caused a decrease of the striatal levels of homovanillic acid (HVA), dihydroxy 3-4 phenylacetic acid (DOPAC) [inhibition of tyrosine hydroxylase (TH) and monoamine oxidase (MAO)] and 3-methoxytyramine (3 MT) (inhibition of release)." | 3.67 | Dynamic characteristics of dopamine, norepinephrine and serotonin metabolism in axonal endings of the rat hypothalamus and striatum during hypoxia: a study using HPLC with electrochemical detection. ( Boismare, F; Chretien, P; Daoust, M; Moore, N; Saligaut, C, 1986) |
| "The concentrations of 3-methoxy-4-hydroxyphenylglycol (MHPG), 5-hydroxyindole-3-acetic acid (5-HIAA) and homovanillic acid (HVA) were determined in CSF of patients with hypoxia due to circulatory arrest." | 3.67 | Biogenic amine metabolites in human CSF after hypoxia due to cardiac arrest. ( Kärkelä, J; Marnela, KM; Odink, J; Thissen, JT, 1989) |
| "Three patients with postanoxic intention myoclonus, two patients with intention tremor, and one patient with cerebral palsy were administered L-5-hydroxytryptophan (L-5HTP), the precursor of serotonin, in combination with MK 486, a peripheral amino acid decarboxylase inhibitor." | 3.65 | Therapy of intention myoclonus with L-5-hydroxytryptophan and a peripheral decarboxylase inhibitor, MK 486. ( Sethy, VH; Van Woert, MH, 1975) |
| "Sudden infant death syndrome (SIDS) is postulated to result from abnormalities in brainstem control of autonomic function and breathing during a critical developmental period." | 1.36 | Brainstem serotonergic deficiency in sudden infant death syndrome. ( Belliveau, RA; Borenstein, NS; Duncan, JR; Haas, EA; Hoffman, JM; Kinney, HC; Krous, HF; Mokler, DJ; Nattie, EE; Paterson, DS; Stanley, C; Trachtenberg, FL, 2010) |
| "Vannucci, Experimental biology of cerebral hypoxia-ischemia: relation to perinatal brain damage, Pediatr." | 1.30 | Anoxic and hypoxic immature rat model for measurement of monoamine using in vivo microdialysis. ( Ishida, A; Nakajima, W; Takada, G, 1999) |
| "During anoxia, the level of the inhibitory transmitter gamma-aminobutyric acid (GABA) increased (2." | 1.28 | Changes in turtle brain neurotransmitters and related substances during anoxia. ( Alfaro, AA; Lutz, PL; Nilsson, GE, 1990) |
| "Posthypoxic action myoclonus is usually associated with impaired serotonin (5-HT) neurotransmission but in some patients 5-HT precursors aggravate and 5-HT blockers improve action myoclonus." | 1.27 | Clinical, biochemical, and pharmacological observation in a patient with postasphyxic myoclonus: association to serotonin hyperactivity. ( De Yebenes, JG; Giménez-Roldán, S; Mateo, D; Muradas, V, 1988) |
| "Postanoxic myoclonus was first accepted as being related to a dysfunction of the ventrolateral thalamic nucleus." | 1.26 | Postanoxic myoclonus. Treatment of a case with 5-hydroxytryptophane and a decarboxylase inhibitor. ( Beretta, E; de Crousaz, G; Regli, F; Steck, AJ, 1981) |
| "In two patients with postanoxic action myoclonus, L-tryptophan or a monoamine oxidase inhibitor induced a moderate improvement, but L-5-hydroxytryptophan had greater therapeutic effect." | 1.26 | Beneficial effects of serotonin precursors in postanoxic action myoclonus. ( De Léan, J; Hornykiewicz, O; Richardson, JC, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (66.67) | 18.7374 |
| 1990's | 8 (22.22) | 18.2507 |
| 2000's | 2 (5.56) | 29.6817 |
| 2010's | 2 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Karpova, IV | 1 |
| Mikheev, VV | 1 |
| Marysheva, VV | 1 |
| Kuritcyna, NA | 1 |
| Bychkov, ER | 1 |
| Shabanov, PD | 1 |
| Duncan, JR | 1 |
| Paterson, DS | 1 |
| Hoffman, JM | 1 |
| Mokler, DJ | 1 |
| Borenstein, NS | 1 |
| Belliveau, RA | 1 |
| Krous, HF | 1 |
| Haas, EA | 1 |
| Stanley, C | 1 |
| Nattie, EE | 1 |
| Trachtenberg, FL | 1 |
| Kinney, HC | 1 |
| Guignabert, C | 1 |
| Izikki, M | 1 |
| Tu, LI | 1 |
| Li, Z | 1 |
| Zadigue, P | 1 |
| Barlier-Mur, AM | 1 |
| Hanoun, N | 1 |
| Rodman, D | 1 |
| Hamon, M | 1 |
| Adnot, S | 1 |
| Eddahibi, S | 1 |
| Thomas, P | 1 |
| Rahman, MS | 1 |
| Khan, IA | 1 |
| Kummer, JA | 1 |
| Beretta, E | 1 |
| Regli, F | 1 |
| de Crousaz, G | 1 |
| Steck, AJ | 1 |
| Hedner, T | 1 |
| Lundborg, P | 1 |
| Silverstein, F | 1 |
| Johnston, MV | 2 |
| Poncet, L | 3 |
| Denoroy, L | 3 |
| Dalmaz, Y | 3 |
| Pequignot, JM | 3 |
| Nakajima, W | 1 |
| Ishida, A | 1 |
| Takada, G | 1 |
| Cottet-Emard, JM | 1 |
| Van Woert, MH | 2 |
| Sethy, VH | 1 |
| De Léan, J | 2 |
| Richardson, JC | 2 |
| Hornykiewicz, O | 1 |
| Steinberg, H | 2 |
| Bassett, DJ | 1 |
| Fisher, AB | 2 |
| Gordon, K | 1 |
| Statman, D | 1 |
| Robinson, TE | 1 |
| Becker, JB | 1 |
| Silverstein, FS | 1 |
| Nilsson, GE | 2 |
| Hadjiconstantinou, M | 1 |
| Yates, AJ | 1 |
| Neff, NH | 1 |
| Alfaro, AA | 1 |
| Lutz, PL | 1 |
| Rosenbaum, D | 1 |
| Chung, EY | 1 |
| Chadwick, D | 1 |
| Hallett, M | 1 |
| Jenner, P | 1 |
| Marsden, CD | 1 |
| Fahn, S | 1 |
| Rewcastle, NB | 1 |
| Freeman, GB | 1 |
| Nielsen, P | 1 |
| Gibson, GE | 1 |
| Miwa, S | 2 |
| Fujiwara, M | 4 |
| Lee, K | 2 |
| Saligaut, C | 1 |
| Chretien, P | 1 |
| Daoust, M | 1 |
| Moore, N | 1 |
| Boismare, F | 1 |
| MacMillan, V | 1 |
| Pouliot, T | 1 |
| de la Noüe, J | 1 |
| Roberge, AG | 1 |
| Giménez-Roldán, S | 1 |
| Mateo, D | 1 |
| Muradas, V | 1 |
| De Yebenes, JG | 1 |
| Burnstock, G | 1 |
| Lincoln, J | 1 |
| Fehér, E | 1 |
| Hopwood, AM | 1 |
| Kirkpatrick, K | 1 |
| Milner, P | 1 |
| Ralevic, V | 1 |
| Odink, J | 1 |
| Kärkelä, J | 1 |
| Thissen, JT | 1 |
| Marnela, KM | 1 |
| Davis, JN | 1 |
| Carlsson, A | 1 |
| Vaĭsfel'd, IL | 1 |
| Il'icheva, RF | 1 |
| Kassil', GN | 1 |
| Bassett, D | 1 |
| Lowy, PH | 1 |
| Keighley, G | 1 |
| Cohen, NS | 1 |
| van Dyke, DH | 1 |
| Cserr, H | 1 |
| Barlow, CF | 1 |
36 other studies available for hydroxyindoleacetic acid and Hypoxia
| Article | Year |
|---|---|
[Central monoaminergic systems sensitivity to acute hypoxia with hypercapnia changes after the maintenance under the long-term social isolation].
Topics: Animals; Brain; Brain Chemistry; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Hypercapnia; | 2018 |
Brainstem serotonergic deficiency in sudden infant death syndrome.
Topics: Autopsy; Brain Stem; Case-Control Studies; Female; Humans; Hydroxyindoleacetic Acid; Hypoxia; Infant | 2010 |
Transgenic mice overexpressing the 5-hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension.
Topics: Acute Disease; Animals; Blood Pressure; Blood Vessels; Humans; Hydroxyindoleacetic Acid; Hypertensio | 2006 |
Widespread endocrine disruption and reproductive impairment in an estuarine fish population exposed to seasonal hypoxia.
Topics: Animals; Ecosystem; Female; Gonadotropin-Releasing Hormone; Hydroxyindoleacetic Acid; Hypoxia; Lutei | 2007 |
Postanoxic myoclonus. Treatment of a case with 5-hydroxytryptophane and a decarboxylase inhibitor.
Topics: 5-Hydroxytryptophan; Benserazide; Humans; Hydrazines; Hydroxyindoleacetic Acid; Hypoxia; Male; Middl | 1981 |
5-HIAA Levels in brain and cerebrospinal fluid of the neonatal rat during oxygen deprivation.
Topics: Animals; Animals, Newborn; Brain Chemistry; Hydroxyindoleacetic Acid; Hypoxia; Monoamine Oxidase; Ra | 1980 |
Effects of hypoxia-ischemia on monoamine metabolism in the immature brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Behavior, Animal; Biogenic Amines; Corpus | 1984 |
Activity of tryptophan hydroxylase and content of indolamines in discrete brain regions after a long-term hypoxic exposure in the rat.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Brain Chemistry; | 1997 |
Effects of carotid sinus nerve transection on changes in neuropeptide Y and indolamines induced by long-term hypoxia in rats.
Topics: Animals; Brain; Carotid Sinus; Chemoreceptor Cells; Corpus Striatum; Denervation; Frontal Lobe; Hydr | 1998 |
Anoxic and hypoxic immature rat model for measurement of monoamine using in vivo microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Brain; Brain Chemistry; Brain Ischemia; C | 1999 |
Altered daily rhythms of brain and pituitary indolamines and neuropeptides in long-term hypoxic rats.
Topics: Animals; Brain; Brain Chemistry; Circadian Rhythm; Hydroxyindoleacetic Acid; Hypoxia; Male; Neuropep | 1999 |
Therapy of intention myoclonus with L-5-hydroxytryptophan and a peripheral decarboxylase inhibitor, MK 486.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Cer | 1975 |
Beneficial effects of serotonin precursors in postanoxic action myoclonus.
Topics: 5-Hydroxytryptophan; Aged; Carbidopa; Female; Humans; Hydroxyindoleacetic Acid; Hypoxia; Levodopa; M | 1976 |
Metabolic requirements for 5-hydroxytryptamine uptake by the isolated lung.
Topics: Animals; Biological Transport, Active; Cyanides; Deoxyglucose; Glucose; Guinea Pigs; Hydroxyindoleac | 1975 |
Transient hypoxia alters striatal catecholamine metabolism in immature brain: an in vivo microdialysis study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Brain Diseases; Corpus Striatum; Dialysis | 1990 |
Turnover of serotonin in brain of an anoxia-tolerant vertebrate, the crucian carp.
Topics: 5-Hydroxytryptophan; Animals; Brain; Carps; Cyprinidae; Hydrazines; Hydroxyindoleacetic Acid; Hypoxi | 1990 |
Hypoxia-induced neurotransmitter deficits in neonatal rats are partially corrected by exogenous GM1 ganglioside.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Animals; Animals, Newborn; Brain; Choline; Corpus Str | 1990 |
Changes in turtle brain neurotransmitters and related substances during anoxia.
Topics: Amino Acids; Animals; Brain; Dopamine; Hydroxyindoleacetic Acid; Hypoxia; Neurotransmitter Agents; S | 1990 |
Biochemistry and therapeutics of posthypoxic myoclonus.
Topics: 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Aspartic Acid; Benzodiazepines; Carbidopa; Electro | 1986 |
Treatment of posthypoxic action myoclonus: implications for the pathophysiology of the disorder.
Topics: 5-Hydroxytryptophan; Benzodiazepines; Clonazepam; Female; Fenclonine; Humans; Hydroxyindoleacetic Ac | 1986 |
Newer drugs for posthypoxic action myoclonus: observations from a well-studied case.
Topics: Clonazepam; Drug Therapy, Combination; Estrogens, Conjugated (USP); Fasting; Female; Humans; Hydroxy | 1986 |
Pathological findings in a case of hypoxic myoclonus treated with 5-hydroxytryptophan and a decarboxylase inhibitor.
Topics: 5-Hydroxytryptophan; Aged; Brain; Carbidopa; Diazepam; Electroencephalography; Female; Fenclonine; H | 1986 |
Monoamine neurotransmitter metabolism and locomotor activity during chemical hypoxia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxyindole | 1986 |
The effects of cinepazide on the content, biosynthesis and turnover of noradrenaline, dopamine and 5-hydroxytryptamine in the rat brain under room air and hypoxia.
Topics: 5-Hydroxytryptophan; Animals; Brain; Dihydroxyphenylalanine; Dopamine; Hydroxyindoleacetic Acid; Hyd | 1986 |
Dynamic characteristics of dopamine, norepinephrine and serotonin metabolism in axonal endings of the rat hypothalamus and striatum during hypoxia: a study using HPLC with electrochemical detection.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Axons; Chromatography, High Pressure Liquid; Corpus Striatu | 1986 |
Effect of probenecid on cerebral and cisternal cerebrospinal fluid lactate content.
Topics: Animals; Brain; Cisterna Magna; Energy Metabolism; Glucose; Homovanillic Acid; Hydroxyindoleacetic A | 1987 |
Determination of serotonin turnover in the rat brain using 6-fluorotryptophan.
Topics: Animals; Brain; Hydroxyindoleacetic Acid; Hypoxia; Male; Probenecid; Rats; Rats, Inbred Strains; Ser | 1987 |
Influence of diet and hypoxia on brain serotonin and catecholamines in rainbow trout (Salmo gairdneri).
Topics: Animals; Brain; Catecholamines; Dietary Proteins; Dopamine; Hydroxyindoleacetic Acid; Hypoxia; Norep | 1988 |
Clinical, biochemical, and pharmacological observation in a patient with postasphyxic myoclonus: association to serotonin hyperactivity.
Topics: 5-Hydroxytryptophan; Aged; Humans; Hydroxyindoleacetic Acid; Hypoxia; Male; Methysergide; Myoclonus; | 1988 |
Serotonin is localized in endothelial cells of coronary arteries and released during hypoxia: a possible new mechanism for hypoxia-induced vasodilatation of the rat heart.
Topics: Animals; Coronary Vessels; Endothelium, Vascular; Hydroxyindoleacetic Acid; Hypoxia; Immunoenzyme Te | 1988 |
Biogenic amine metabolites in human CSF after hypoxia due to cardiac arrest.
Topics: Aged; Aged, 80 and over; Biogenic Amines; Female; Glycols; Heart Arrest; Homovanillic Acid; Humans; | 1989 |
The effect of hypoxia on monoamine synthesis, levels and metabolism in rat brain.
Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Brain; Dihydroxyphenylalanine; Dopamine; Fluorometry; | 1973 |
[The diurnal rhythm of biogenic amines in man under normal conditions and in hypoxia].
Topics: Adult; Aerospace Medicine; Amine Oxidase (Copper-Containing); Circadian Rhythm; Diuresis; Female; Hi | 1974 |
Energy utilization by the lung.
Topics: Adenosine Triphosphate; Aerobiosis; Anaerobiosis; Animals; Capillaries; Carbon Radioisotopes; Cyanid | 1974 |
Stimulation by serotonin of erythropoietin-dependent erythropoiesis in mice.
Topics: 5-Hydroxytryptophan; Animals; Epinephrine; Erythropoiesis; Erythropoietin; Female; Hematocrit; Hemog | 1970 |
5-Hydroxyindoleacetic acid (5-HIAA) transport by isolated choroid plexus.
Topics: Aminohippuric Acids; Anesthesia; Animals; Biological Transport, Active; Carbon Isotopes; Choroid Ple | 1970 |