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hydroxyindoleacetic acid and Hypothermia, Accidental

hydroxyindoleacetic acid has been researched along with Hypothermia, Accidental in 20 studies

(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.

Research Excerpts

ExcerptRelevanceReference
" The 5-HT1A antagonist WAY 100635 decreased 5-HTP-induced hypothermia in SERT+/+ and +/- mice with no effect in SERT-/- mice, whereas the 5-HT7 antagonist SB 269970 decreased this exaggerated response in SERT-/- mice only."3.74Neurochemical, behavioral, and physiological effects of pharmacologically enhanced serotonin levels in serotonin transporter (SERT)-deficient mice. ( Fox, MA; French, HT; Huang, SJ; Jensen, CL; Murphy, DL; Stein, AR; Tolliver, TJ, 2008)
" In vivo, NAE-086 induced all the typical effects of a 5-HT(1A) receptor agonist in rats: it decreased 5-HT synthesis (5-HTP accumulation) and 5-HT turnover (measured as the ratio of 5-hydroxyindoleacetic acid/5-HT), increased corticosterone secretion, induced the 5-HT(1A) syndrome (flat body posture and forepaw treading), inhibited the cage-leaving response, and caused hypothermia."3.71The pharmacological profile of (R)-3,4-dihydro-N-isopropyl-3-(N-isopropyl-N-propylamino)-2H-1-benzopyran-5-carboxamide, a selective 5-hydroxytryptamine(1A) receptor agonist. ( Evenden, JL; Fowler, CJ; Jerning, E; Kelder, D; Lake-Bakaar, D; Larsson, LG; Mohell, N; Rënyi, L; Ross, SB; Sällemark, M, 2001)
"Alcoholism is a complex disorder involving, among others, the serotoninergic (5-HT) system, mainly regulated by 5-HT(1A) autoreceptors in the dorsal raphe nucleus."1.35Chronic voluntary ethanol intake hypersensitizes 5-HT(1A) autoreceptors in C57BL/6J mice. ( Chouchana, L; Hamon, M; Hanoun, N; Kelaï, S; Lanfumey, L; Renoir, T; Saurini, F, 2008)
"Sumatriptan failed to produce either of these effects due to a poor brain penetration."1.295-HT1D receptor agonist properties of novel 2-[5-[[(trifluoromethyl)sulfonyl]oxy]indolyl]ethylamines and their use as synthetic intermediates. ( Barf, TA; de Boer, P; Ennis, MD; Ghazal, NB; McGuire, JC; Peroutka, SJ; Smith, MW; Swensson, K; Wikström, H, 1996)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19909 (45.00)18.7374
1990's4 (20.00)18.2507
2000's6 (30.00)29.6817
2010's1 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fox, MA1
Jensen, CL1
French, HT1
Stein, AR1
Huang, SJ1
Tolliver, TJ1
Murphy, DL1
Kelaï, S1
Renoir, T1
Chouchana, L1
Saurini, F1
Hanoun, N1
Hamon, M1
Lanfumey, L1
Jacobsen, JP1
Siesser, WB1
Sachs, BD1
Peterson, S1
Cools, MJ1
Setola, V1
Folgering, JH1
Flik, G1
Caron, MG1
Bull, EJ1
Hutson, PH1
Fone, KC1
BARTLET, AL1
Roberts, J1
Rosenfeld, HJ1
Kloos, RT1
Mousseau, DD1
Rao, VL1
Butterworth, RF1
Barf, TA1
de Boer, P1
Wikström, H1
Peroutka, SJ1
Swensson, K1
Ennis, MD1
Ghazal, NB1
McGuire, JC1
Smith, MW1
Aguirre, N2
Ballaz, S1
Lasheras, B2
Del Río, J1
Cryan, JF1
Harkin, A1
Naughton, M1
Kelly, JP1
Leonard, BE2
Hervías, I1
Rënyi, L1
Evenden, JL1
Fowler, CJ1
Jerning, E1
Kelder, D1
Lake-Bakaar, D1
Larsson, LG1
Mohell, N1
Sällemark, M1
Ross, SB1
Okuda, C1
Saito, A1
Miyazaki, M1
Kuriyama, K1
Alari, L1
Sjöquist, B1
Lewander, T1
Shallice, SA1
Grabowska, M1
Michaluk, J1
Antkiewicz, L1
Sasame, HA1
Perez-Cruet, J1
Di Chiara, G1
Tagliamonte, A1
Tagliamonte, P1
Gessa, GL1
Barofsky, I1
Feldstein, A1
Holtzman, D1
Lovell, RA1
Jaffe, JH1
Freedman, DX1

Reviews

1 review available for hydroxyindoleacetic acid and Hypothermia, Accidental

ArticleYear
Spontaneous periodic hypothermia.
    Medicine, 1995, Volume: 74, Issue:5

    Topics: Anticonvulsants; Aspartate Aminotransferases; Carbamazepine; Cerebral Ventricles; Humans; Hydroxyind

1995

Other Studies

19 other studies available for hydroxyindoleacetic acid and Hypothermia, Accidental

ArticleYear
Neurochemical, behavioral, and physiological effects of pharmacologically enhanced serotonin levels in serotonin transporter (SERT)-deficient mice.
    Psychopharmacology, 2008, Volume: 201, Issue:2

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Brain Chemistry; Catech

2008
Chronic voluntary ethanol intake hypersensitizes 5-HT(1A) autoreceptors in C57BL/6J mice.
    Journal of neurochemistry, 2008, Volume: 107, Issue:6

    Topics: 5-Hydroxytryptophan; Action Potentials; Alcohol Drinking; Alcoholism; Animals; Behavior, Animal; Bod

2008
Deficient serotonin neurotransmission and depression-like serotonin biomarker alterations in tryptophan hydroxylase 2 (Tph2) loss-of-function mice.
    Molecular psychiatry, 2012, Volume: 17, Issue:7

    Topics: Animals; Behavior, Animal; Biomarkers; Corticosterone; Depression; Disease Models, Animal; Extracell

2012
Reduced social interaction following 3,4-methylenedioxymethamphetamine is not associated with enhanced 5-HT 2C receptor responsivity.
    Neuropharmacology, 2003, Volume: 44, Issue:4

    Topics: Animals; Brain; Corticosterone; Exploratory Behavior; Hydroxyindoleacetic Acid; Hypothermia; In Vitr

2003
THE INFLUENCE OF CHLORPROMAZINE ON THE METABOLISM OF 5-HYDROXYTRYPTAMINE IN THE MOUSE.
    British journal of pharmacology and chemotherapy, 1965, Volume: 24

    Topics: Animals; Brain Chemistry; Chlorpromazine; Creatine; Creatinine; Hydrazines; Hydroxyindoleacetic Acid

1965
Hypothermia induced in mice by enzyme-mediated depletion of serotonin.
    Experientia, 1980, Jul-15, Volume: 36, Issue:7

    Topics: Animals; Body Temperature; Brain; Female; Hydroxyindoleacetic Acid; Hypothermia; Indoles; Mice; Mixe

1980
Alterations in serotonin parameters in brain of thiamine-deficient rats are evident prior to the appearance of neurological symptoms.
    Journal of neurochemistry, 1996, Volume: 67, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amines; Animals; Autoradiography; Brain; Brain Chemistry; Ch

1996
5-HT1D receptor agonist properties of novel 2-[5-[[(trifluoromethyl)sulfonyl]oxy]indolyl]ethylamines and their use as synthetic intermediates.
    Journal of medicinal chemistry, 1996, Nov-22, Volume: 39, Issue:24

    Topics: 5-Hydroxytryptophan; Acrylamides; Animals; Brain; CHO Cells; Cricetinae; Cyclic AMP; Ethylamines; Gu

1996
MDMA ('Ecstasy') enhances 5-HT1A receptor density and 8-OH-DPAT-induced hypothermia: blockade by drugs preventing 5-hydroxytryptamine depletion.
    European journal of pharmacology, 1998, Apr-10, Volume: 346, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Hydroxyindoleacetic Acid; Hypotha

1998
Characterization of D-fenfluramine-induced hypothermia: evidence for multiple sites of action.
    European journal of pharmacology, 2000, Mar-03, Volume: 390, Issue:3

    Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Benzofurans; Body Temperature; Cerebral

2000
2-Deoxy-D-glucose prevents and nicotinamide potentiates 3, 4-methylenedioxymethamphetamine-induced serotonin neurotoxicity.
    Journal of neurochemistry, 2000, Volume: 75, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine Triphosphate; Animals; Body Temperature; Brain; Carrier Pr

2000
The pharmacological profile of (R)-3,4-dihydro-N-isopropyl-3-(N-isopropyl-N-propylamino)-2H-1-benzopyran-5-carboxamide, a selective 5-hydroxytryptamine(1A) receptor agonist.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Benzopyrans; Corticosterone; Cyclic AMP; Dihydroxyph

2001
Alteration of the turnover of dopamine and 5-hydroxytryptamine in rat brain associated with hypothermia.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Brain; Corticosterone; Dihydroxyphenylalan

1986
Ethanol-induced hypothermia and biogenic amine metabolites.
    Drug and alcohol dependence, 1987, Volume: 19, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Brain Chemistry; Ethanol; Homovanillic Aci

1987
The effects of some tryptamine derivatives on brain monoamines and their precursor amino acids.
    Neuropharmacology, 1972, Volume: 11, Issue:3

    Topics: Amines; Amino Acids; Aminobutyrates; Animals; Behavior, Animal; Brain; Brain Chemistry; Circadian Rh

1972
Possible involvement of brain serotonin in apomorphine-induced hypothermia.
    European journal of pharmacology, 1973, Volume: 23, Issue:1

    Topics: Animals; Apomorphine; Body Temperature; Brain Chemistry; Butyrophenones; Drug Interactions; Fencloni

1973
Evidence that methadone blocks dopamine receptors in the brain.
    Journal of neurochemistry, 1972, Volume: 19, Issue:8

    Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Basal Ganglia; Brain; Brain Chemistry; Butyrophenones; Ca

1972
Serotonin and its metabolites: their respective roles in the production of hypothermia in the mouse.
    Experientia, 1970, Sep-26, Volume: 26, Issue:9

    Topics: 5-Hydroxytryptophan; Animals; Body Temperature; Ethanol; Hydroxyindoleacetic Acid; Hypothermia; Indo

1970
1-delta9-tetrahydrocannabinol: neurochemical and behavioral effects in the mouse.
    Science (New York, N.Y.), 1969, Mar-28, Volume: 163, Issue:3874

    Topics: Animals; Ataxia; Behavior, Animal; Benzopyrans; Brain; Cannabis; Female; Hydroxyindoleacetic Acid; H

1969