hydroxyindoleacetic acid has been researched along with Hypothermia, Accidental in 20 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The 5-HT1A antagonist WAY 100635 decreased 5-HTP-induced hypothermia in SERT+/+ and +/- mice with no effect in SERT-/- mice, whereas the 5-HT7 antagonist SB 269970 decreased this exaggerated response in SERT-/- mice only." | 3.74 | Neurochemical, behavioral, and physiological effects of pharmacologically enhanced serotonin levels in serotonin transporter (SERT)-deficient mice. ( Fox, MA; French, HT; Huang, SJ; Jensen, CL; Murphy, DL; Stein, AR; Tolliver, TJ, 2008) |
| " In vivo, NAE-086 induced all the typical effects of a 5-HT(1A) receptor agonist in rats: it decreased 5-HT synthesis (5-HTP accumulation) and 5-HT turnover (measured as the ratio of 5-hydroxyindoleacetic acid/5-HT), increased corticosterone secretion, induced the 5-HT(1A) syndrome (flat body posture and forepaw treading), inhibited the cage-leaving response, and caused hypothermia." | 3.71 | The pharmacological profile of (R)-3,4-dihydro-N-isopropyl-3-(N-isopropyl-N-propylamino)-2H-1-benzopyran-5-carboxamide, a selective 5-hydroxytryptamine(1A) receptor agonist. ( Evenden, JL; Fowler, CJ; Jerning, E; Kelder, D; Lake-Bakaar, D; Larsson, LG; Mohell, N; Rënyi, L; Ross, SB; Sällemark, M, 2001) |
| "Alcoholism is a complex disorder involving, among others, the serotoninergic (5-HT) system, mainly regulated by 5-HT(1A) autoreceptors in the dorsal raphe nucleus." | 1.35 | Chronic voluntary ethanol intake hypersensitizes 5-HT(1A) autoreceptors in C57BL/6J mice. ( Chouchana, L; Hamon, M; Hanoun, N; Kelaï, S; Lanfumey, L; Renoir, T; Saurini, F, 2008) |
| "Sumatriptan failed to produce either of these effects due to a poor brain penetration." | 1.29 | 5-HT1D receptor agonist properties of novel 2-[5-[[(trifluoromethyl)sulfonyl]oxy]indolyl]ethylamines and their use as synthetic intermediates. ( Barf, TA; de Boer, P; Ennis, MD; Ghazal, NB; McGuire, JC; Peroutka, SJ; Smith, MW; Swensson, K; Wikström, H, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (45.00) | 18.7374 |
| 1990's | 4 (20.00) | 18.2507 |
| 2000's | 6 (30.00) | 29.6817 |
| 2010's | 1 (5.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fox, MA | 1 |
| Jensen, CL | 1 |
| French, HT | 1 |
| Stein, AR | 1 |
| Huang, SJ | 1 |
| Tolliver, TJ | 1 |
| Murphy, DL | 1 |
| Kelaï, S | 1 |
| Renoir, T | 1 |
| Chouchana, L | 1 |
| Saurini, F | 1 |
| Hanoun, N | 1 |
| Hamon, M | 1 |
| Lanfumey, L | 1 |
| Jacobsen, JP | 1 |
| Siesser, WB | 1 |
| Sachs, BD | 1 |
| Peterson, S | 1 |
| Cools, MJ | 1 |
| Setola, V | 1 |
| Folgering, JH | 1 |
| Flik, G | 1 |
| Caron, MG | 1 |
| Bull, EJ | 1 |
| Hutson, PH | 1 |
| Fone, KC | 1 |
| BARTLET, AL | 1 |
| Roberts, J | 1 |
| Rosenfeld, HJ | 1 |
| Kloos, RT | 1 |
| Mousseau, DD | 1 |
| Rao, VL | 1 |
| Butterworth, RF | 1 |
| Barf, TA | 1 |
| de Boer, P | 1 |
| Wikström, H | 1 |
| Peroutka, SJ | 1 |
| Swensson, K | 1 |
| Ennis, MD | 1 |
| Ghazal, NB | 1 |
| McGuire, JC | 1 |
| Smith, MW | 1 |
| Aguirre, N | 2 |
| Ballaz, S | 1 |
| Lasheras, B | 2 |
| Del Río, J | 1 |
| Cryan, JF | 1 |
| Harkin, A | 1 |
| Naughton, M | 1 |
| Kelly, JP | 1 |
| Leonard, BE | 2 |
| Hervías, I | 1 |
| Rënyi, L | 1 |
| Evenden, JL | 1 |
| Fowler, CJ | 1 |
| Jerning, E | 1 |
| Kelder, D | 1 |
| Lake-Bakaar, D | 1 |
| Larsson, LG | 1 |
| Mohell, N | 1 |
| Sällemark, M | 1 |
| Ross, SB | 1 |
| Okuda, C | 1 |
| Saito, A | 1 |
| Miyazaki, M | 1 |
| Kuriyama, K | 1 |
| Alari, L | 1 |
| Sjöquist, B | 1 |
| Lewander, T | 1 |
| Shallice, SA | 1 |
| Grabowska, M | 1 |
| Michaluk, J | 1 |
| Antkiewicz, L | 1 |
| Sasame, HA | 1 |
| Perez-Cruet, J | 1 |
| Di Chiara, G | 1 |
| Tagliamonte, A | 1 |
| Tagliamonte, P | 1 |
| Gessa, GL | 1 |
| Barofsky, I | 1 |
| Feldstein, A | 1 |
| Holtzman, D | 1 |
| Lovell, RA | 1 |
| Jaffe, JH | 1 |
| Freedman, DX | 1 |
1 review available for hydroxyindoleacetic acid and Hypothermia, Accidental
| Article | Year |
|---|---|
Spontaneous periodic hypothermia.
Topics: Anticonvulsants; Aspartate Aminotransferases; Carbamazepine; Cerebral Ventricles; Humans; Hydroxyind | 1995 |
19 other studies available for hydroxyindoleacetic acid and Hypothermia, Accidental
| Article | Year |
|---|---|
Neurochemical, behavioral, and physiological effects of pharmacologically enhanced serotonin levels in serotonin transporter (SERT)-deficient mice.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Brain Chemistry; Catech | 2008 |
Chronic voluntary ethanol intake hypersensitizes 5-HT(1A) autoreceptors in C57BL/6J mice.
Topics: 5-Hydroxytryptophan; Action Potentials; Alcohol Drinking; Alcoholism; Animals; Behavior, Animal; Bod | 2008 |
Deficient serotonin neurotransmission and depression-like serotonin biomarker alterations in tryptophan hydroxylase 2 (Tph2) loss-of-function mice.
Topics: Animals; Behavior, Animal; Biomarkers; Corticosterone; Depression; Disease Models, Animal; Extracell | 2012 |
Reduced social interaction following 3,4-methylenedioxymethamphetamine is not associated with enhanced 5-HT 2C receptor responsivity.
Topics: Animals; Brain; Corticosterone; Exploratory Behavior; Hydroxyindoleacetic Acid; Hypothermia; In Vitr | 2003 |
THE INFLUENCE OF CHLORPROMAZINE ON THE METABOLISM OF 5-HYDROXYTRYPTAMINE IN THE MOUSE.
Topics: Animals; Brain Chemistry; Chlorpromazine; Creatine; Creatinine; Hydrazines; Hydroxyindoleacetic Acid | 1965 |
Hypothermia induced in mice by enzyme-mediated depletion of serotonin.
Topics: Animals; Body Temperature; Brain; Female; Hydroxyindoleacetic Acid; Hypothermia; Indoles; Mice; Mixe | 1980 |
Alterations in serotonin parameters in brain of thiamine-deficient rats are evident prior to the appearance of neurological symptoms.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amines; Animals; Autoradiography; Brain; Brain Chemistry; Ch | 1996 |
5-HT1D receptor agonist properties of novel 2-[5-[[(trifluoromethyl)sulfonyl]oxy]indolyl]ethylamines and their use as synthetic intermediates.
Topics: 5-Hydroxytryptophan; Acrylamides; Animals; Brain; CHO Cells; Cricetinae; Cyclic AMP; Ethylamines; Gu | 1996 |
MDMA ('Ecstasy') enhances 5-HT1A receptor density and 8-OH-DPAT-induced hypothermia: blockade by drugs preventing 5-hydroxytryptamine depletion.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Hydroxyindoleacetic Acid; Hypotha | 1998 |
Characterization of D-fenfluramine-induced hypothermia: evidence for multiple sites of action.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Benzofurans; Body Temperature; Cerebral | 2000 |
2-Deoxy-D-glucose prevents and nicotinamide potentiates 3, 4-methylenedioxymethamphetamine-induced serotonin neurotoxicity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine Triphosphate; Animals; Body Temperature; Brain; Carrier Pr | 2000 |
The pharmacological profile of (R)-3,4-dihydro-N-isopropyl-3-(N-isopropyl-N-propylamino)-2H-1-benzopyran-5-carboxamide, a selective 5-hydroxytryptamine(1A) receptor agonist.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Benzopyrans; Corticosterone; Cyclic AMP; Dihydroxyph | 2001 |
Alteration of the turnover of dopamine and 5-hydroxytryptamine in rat brain associated with hypothermia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Brain; Corticosterone; Dihydroxyphenylalan | 1986 |
Ethanol-induced hypothermia and biogenic amine metabolites.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Brain Chemistry; Ethanol; Homovanillic Aci | 1987 |
The effects of some tryptamine derivatives on brain monoamines and their precursor amino acids.
Topics: Amines; Amino Acids; Aminobutyrates; Animals; Behavior, Animal; Brain; Brain Chemistry; Circadian Rh | 1972 |
Possible involvement of brain serotonin in apomorphine-induced hypothermia.
Topics: Animals; Apomorphine; Body Temperature; Brain Chemistry; Butyrophenones; Drug Interactions; Fencloni | 1973 |
Evidence that methadone blocks dopamine receptors in the brain.
Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Basal Ganglia; Brain; Brain Chemistry; Butyrophenones; Ca | 1972 |
Serotonin and its metabolites: their respective roles in the production of hypothermia in the mouse.
Topics: 5-Hydroxytryptophan; Animals; Body Temperature; Ethanol; Hydroxyindoleacetic Acid; Hypothermia; Indo | 1970 |
1-delta9-tetrahydrocannabinol: neurochemical and behavioral effects in the mouse.
Topics: Animals; Ataxia; Behavior, Animal; Benzopyrans; Brain; Cannabis; Female; Hydroxyindoleacetic Acid; H | 1969 |