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hydroxyindoleacetic acid and Hepatolenticular Degeneration

hydroxyindoleacetic acid has been researched along with Hepatolenticular Degeneration in 8 studies

(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.

Hepatolenticular Degeneration: A rare autosomal recessive disease characterized by the deposition of copper in the BRAIN; LIVER; CORNEA; and other organs. It is caused by defects in the ATP7B gene encoding copper-transporting ATPase 2 (EC 3.6.3.4), also known as the Wilson disease protein. The overload of copper inevitably leads to progressive liver and neurological dysfunction such as LIVER CIRRHOSIS; TREMOR; ATAXIA and intellectual deterioration. Hepatic dysfunction may precede neurologic dysfunction by several years.

Research Excerpts

ExcerptRelevanceReference
"Treatment with tetrabenazine did not significantly alter the metabolite levels in patients in whom it produced either improvement, or side effects."1.26CSF studies on the relationship between dopamine and 5-hydroxytryptamine in Parkinsonism and other movement disorders. ( Davidson, DL; Mawdsley, C; Pullar, IA; Wilson, H; Yates, CM, 1977)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19908 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
SOURKES, TL1
MURPHY, GF1
SANKOFF, I1
WISEMAN-DISTLER, MH1
SAINTCYR, S1
Nyberg, P1
Gottfries, CG1
Holmgren, G1
Persson, S1
Roos, BE1
Winblad, B1
Davidson, DL1
Yates, CM1
Mawdsley, C1
Pullar, IA1
Wilson, H1
Nijeholt, JL1
Korf, J1
Genefke, IK1
Garel, A1
Mandel, P1
O'Reilly, S1
Loncin, M1
Cooksey, B1
Warner, RR1
Sternlieb, I1
Gandullia, E1

Other Studies

8 other studies available for hydroxyindoleacetic acid and Hepatolenticular Degeneration

ArticleYear
EXCRETION OF DOPAMINE, CATECHOLAMINE METABOLITES AND 5-HYDROXYINDOLEACETIC ACID IN HEPATOLENTICULAR DEGENERATION (WILSON'S DISEASE).
    Journal of neurochemistry, 1963, Volume: 10

    Topics: Adolescent; Child; Chromatography; Creatine; Creatinine; Dopamine; Epinephrine; Hepatolenticular Deg

1963
Advanced catecholaminergic disturbances in the brain in a case of Wilson's disease.
    Acta neurologica Scandinavica, 1982, Volume: 65, Issue:1

    Topics: Adolescent; Brain; Catecholamines; Dopamine; Female; Hepatolenticular Degeneration; Homovanillic Aci

1982
CSF studies on the relationship between dopamine and 5-hydroxytryptamine in Parkinsonism and other movement disorders.
    Journal of neurology, neurosurgery, and psychiatry, 1977, Volume: 40, Issue:12

    Topics: Aged; Athetosis; Carbidopa; Chorea; Dihydroxyphenylalanine; Dopamine; Dystonia Musculorum Deformans;

1977
Wilson's disease and monoamines.
    Archives of neurology, 1978, Volume: 35, Issue:9

    Topics: Adult; Hepatolenticular Degeneration; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Pen

1978
Factors influencing free serotonin in human plasma.
    Clinica chimica acta; international journal of clinical chemistry, 1968, Volume: 20, Issue:1

    Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Platelets; Ceruloplasmin; Hepatolenticular Degeneration; H

1968
Dopamine and basal ganglia disorders.
    Neurology, 1965, Volume: 15, Issue:11

    Topics: Adult; Basal Ganglia; Dopamine; Female; Hepatolenticular Degeneration; Humans; Hydroxyindoleacetic A

1965
Study of a possible physiologic interaction between ceruloplasmin and serotonin.
    The Journal of laboratory and clinical medicine, 1966, Volume: 67, Issue:6

    Topics: Adolescent; Adult; Aged; Ceruloplasmin; Child; Female; Hepatolenticular Degeneration; Humans; Hydrox

1966
[Metabolism of serotonin in Wilson's disease].
    Minerva pediatrica, 1966, Dec-01, Volume: 18, Issue:37

    Topics: Adolescent; Child; Hepatolenticular Degeneration; Humans; Hydroxyindoleacetic Acid; Male; Serotonin

1966