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hydroxyindoleacetic acid and Fibromyalgia

hydroxyindoleacetic acid has been researched along with Fibromyalgia in 6 studies

(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.

Fibromyalgia: A common nonarticular rheumatic syndrome characterized by myalgia and multiple points of focal muscle tenderness to palpation (trigger points). Muscle pain is typically aggravated by inactivity or exposure to cold. This condition is often associated with general symptoms, such as sleep disturbances, fatigue, stiffness, HEADACHES, and occasionally DEPRESSION. There is significant overlap between fibromyalgia and the chronic fatigue syndrome (FATIGUE SYNDROME, CHRONIC). Fibromyalgia may arise as a primary or secondary disease process. It is most frequent in females aged 20 to 50 years. (From Adams et al., Principles of Neurology, 6th ed, p1494-95)

Research Excerpts

ExcerptRelevanceReference
"Fibromyalgia (FM) is a prevalent syndrome with chronic pain and a hypothesised underlying disturbance of the tryptophan (TRP) metabolism."7.72Experimental evaluation of an altered tryptophan metabolism in fibromyalgia. ( Ackenheil, M; Neumeister, A; Offenbaecher, M; Schwarz, MJ, 2003)
"Fibromyalgia (FM) is a prevalent syndrome with chronic pain and a hypothesized underlying disturbance of the tryptophan (TRP) metabolism."7.71Evidence for an altered tryptophan metabolism in fibromyalgia. ( Ackenheil, M; Ewert, T; Lossau, K; Neumeister, A; Offenbaecher, M; Praschak-Rieder, N; Schwarz, MJ; Stucki, G; Weisser, R; Willeit, M; Zach, J; Zacherl, M, 2002)
"Fibromyalgia (FM) is a prevalent syndrome with chronic pain and a hypothesised underlying disturbance of the tryptophan (TRP) metabolism."3.72Experimental evaluation of an altered tryptophan metabolism in fibromyalgia. ( Ackenheil, M; Neumeister, A; Offenbaecher, M; Schwarz, MJ, 2003)
"Fibromyalgia (FM) is a prevalent syndrome with chronic pain and a hypothesized underlying disturbance of the tryptophan (TRP) metabolism."3.71Evidence for an altered tryptophan metabolism in fibromyalgia. ( Ackenheil, M; Ewert, T; Lossau, K; Neumeister, A; Offenbaecher, M; Praschak-Rieder, N; Schwarz, MJ; Stucki, G; Weisser, R; Willeit, M; Zach, J; Zacherl, M, 2002)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (50.00)18.2507
2000's2 (33.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nishiyori, M1
Nagai, J1
Nakazawa, T1
Ueda, H1
Schwarz, MJ3
Offenbaecher, M2
Neumeister, A2
Ewert, T1
Willeit, M1
Praschak-Rieder, N1
Zach, J1
Zacherl, M1
Lossau, K1
Weisser, R1
Stucki, G1
Ackenheil, M3
Späth, M1
Müller-Bardorff, H1
Pongratz, DE1
Bondy, B1
Russell, IJ1
Vaeroy, H1
Javors, M1
Nyberg, F1
Houvenagel, E1
Forzy, G1
Leloire, O1
Gallois, P1
Hary, S1
Hautecoeur, P1
Convain, L1
Henniaux, M1
Vincent, G1
Dhondt, JL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect Of High Intensity Interval Upper Extremity Training On Biochemistry Parameters And Disease Symptoms In Patients With Fibromyalgia[NCT05502003]33 participants (Actual)Interventional2022-08-25Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

6 other studies available for hydroxyindoleacetic acid and Fibromyalgia

ArticleYear
Absence of morphine analgesia and its underlying descending serotonergic activation in an experimental mouse model of fibromyalgia.
    Neuroscience letters, 2010, Mar-26, Volume: 472, Issue:3

    Topics: Animals; Cold Temperature; Fibromyalgia; Hydroxyindoleacetic Acid; Injections; Male; Mice; Mice, Inb

2010
Evidence for an altered tryptophan metabolism in fibromyalgia.
    Neurobiology of disease, 2002, Volume: 11, Issue:3

    Topics: Adult; Case-Control Studies; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay

2002
Experimental evaluation of an altered tryptophan metabolism in fibromyalgia.
    Advances in experimental medicine and biology, 2003, Volume: 527

    Topics: Adult; Case-Control Studies; Cross-Over Studies; Double-Blind Method; Female; Fibromyalgia; Humans;

2003
Relationship of substance P, 5-hydroxyindole acetic acid and tryptophan in serum of fibromyalgia patients.
    Neuroscience letters, 1999, Jan-15, Volume: 259, Issue:3

    Topics: Adult; Biomarkers; Female; Fibromyalgia; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Pain;

1999
Cerebrospinal fluid biogenic amine metabolites in fibromyalgia/fibrositis syndrome and rheumatoid arthritis.
    Arthritis and rheumatism, 1992, Volume: 35, Issue:5

    Topics: Adult; Aged; Arthritis, Rheumatoid; Biogenic Amines; Female; Fibromyalgia; Humans; Hydroxyindoleacet

1992
[Cerebrospinal fluid monoamines in primary fibromyalgia].
    Revue du rhumatisme et des maladies osteo-articulaires, 1990, Volume: 57, Issue:1

    Topics: Adult; Chronic Disease; Dopamine; Female; Fibromyalgia; Homovanillic Acid; Humans; Hydroxyindoleacet

1990