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hydroxyindoleacetic acid and Epilepsy, Temporal Lobe

hydroxyindoleacetic acid has been researched along with Epilepsy, Temporal Lobe in 10 studies

(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.

Epilepsy, Temporal Lobe: A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the TEMPORAL LOBE, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic. (From Adams et al., Principles of Neurology, 6th ed, p321).

Research Excerpts

ExcerptRelevanceReference
"Cerebrospinal fluid (CSF) concentrations of 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA) and probenecid were examined in 14 children with epilepsy (ages 6 months to 17 years) and 17 controls (ages 14 months to 16 years)."7.65Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy. ( Bowers, MB; Cohen, DJ; Shaywitz, BA, 1975)
"Cerebrospinal fluid (CSF) concentrations of 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA) and probenecid were examined in 14 children with epilepsy (ages 6 months to 17 years) and 17 controls (ages 14 months to 16 years)."3.65Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy. ( Bowers, MB; Cohen, DJ; Shaywitz, BA, 1975)
"Homovanillic acid accumulation was decreased in this group."1.26Dopamine, noradrenaline and serotonin spinal fluid metabolites in temporal lobe epileptic patients with schizophrenic symptomatology. ( Peters, JG, 1979)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19909 (90.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Núñez-Ochoa, MA1
Chiprés-Tinajero, GA1
Medina-Ceja, L1
Bibileĭshvili, ShI1
Young, SN1
Joseph, MH1
Gauthier, S1
Eichelman, B1
Peters, JG1
Mandell, AJ1
Shaywitz, BA1
Cohen, DJ1
Bowers, MB1
Rapoport, JL1
Riekkinen, PJ1
Pitkänen, A1
Halonen, T1
Lehtinen, M1
Ylinen, A1
Sivenius, J1
Garelis, E1
Sourkes, TL1

Reviews

1 review available for hydroxyindoleacetic acid and Epilepsy, Temporal Lobe

ArticleYear
The limbic system and aggression in humans.
    Neuroscience and biobehavioral reviews, 1983,Fall, Volume: 7, Issue:3

    Topics: Aggression; Amygdala; Anticonvulsants; Brain Diseases; Brain Mapping; Brain Neoplasms; Electroenceph

1983

Trials

1 trial available for hydroxyindoleacetic acid and Epilepsy, Temporal Lobe

ArticleYear
Effect of gamma-vinyl GABA treatment on cholinergic and aminergic neurotransmission and on cyclic nucleotides in human complex partial epilepsy--a CSF study.
    Progress in neuro-psychopharmacology & biological psychiatry, 1988, Volume: 12, Issue:1

    Topics: Acetylcholinesterase; Adult; Aminocaproates; Anticonvulsants; Brain; Epilepsy, Temporal Lobe; Female

1988

Other Studies

8 other studies available for hydroxyindoleacetic acid and Epilepsy, Temporal Lobe

ArticleYear
Evaluation of the hippocampal immunoreactivity of the serotonin 5-HT1A, 5-HT2 and 5-HT7 receptors in a pilocarpine temporal lobe epilepsy rat model with fast ripples.
    Neuroreport, 2021, 03-03, Volume: 32, Issue:4

    Topics: Animals; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Dentate Gyrus; Disease Models, Animal; Ep

2021
[Amino acid, tryptophan, as an antiepileptic agent].
    Klinicheskaia meditsina, 1980, Volume: 58, Issue:1

    Topics: Anticonvulsants; Drug Evaluation; Epilepsy; Epilepsy, Temporal Lobe; Humans; Hydroxyindoleacetic Aci

1980
Studies on kynurenine in human cerebrospinal fluid: lowered levels in epilepsy.
    Journal of neural transmission, 1983, Volume: 58, Issue:3-4

    Topics: Adolescent; Adult; Aged; Amino Acids; Anticonvulsants; Epilepsy; Epilepsy, Temporal Lobe; Humans; Hy

1983
Dopamine, noradrenaline and serotonin spinal fluid metabolites in temporal lobe epileptic patients with schizophrenic symptomatology.
    European neurology, 1979, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Child; Dopamine; Epilepsy, Temporal Lobe; Homovanillic Acid; Humans; Hydroxyindol

1979
On a mechanism for the mood and personality changes of adult and later life. A psychobiological hypothesis.
    The Journal of nervous and mental disease, 1979, Volume: 167, Issue:8

    Topics: Affect; Aging; Animals; Antidepressive Agents, Tricyclic; Bipolar Disorder; Brain; Clomipramine; Dom

1979
Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy.
    Neurology, 1975, Volume: 25, Issue:1

    Topics: Acetazolamide; Adolescent; Age Factors; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy

1975
Childhood obsessive compulsive disorder.
    Journal of child psychology and psychiatry, and allied disciplines, 1986, Volume: 27, Issue:3

    Topics: Adolescent; Anorexia Nervosa; Behavior Therapy; Child; Child, Preschool; Clomipramine; Epilepsy, Tem

1986
Use of cerebrospinal fluid drawn at pneumoencephalography in the study of monoamine metabolism in man.
    Journal of neurology, neurosurgery, and psychiatry, 1974, Volume: 37, Issue:6

    Topics: Adolescent; Adult; Brain Diseases; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Homovani

1974