hydroxyindoleacetic acid has been researched along with Epilepsies, Myoclonic in 11 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
Epilepsies, Myoclonic: A clinically diverse group of epilepsy syndromes characterized either by myoclonic seizures or by myoclonus in association with other seizure types. Myoclonic epilepsy syndromes are divided into three subtypes based on etiology: familial, cryptogenic, and symptomatic.
| Excerpt | Relevance | Reference |
|---|---|---|
| " A patient with Lafora disease reported enough improvement in myoclonus-evoked convulsions to continue chronic use of the drug." | 2.68 | Neuropharmacology of progressive myoclonus epilepsy: response to 5-hydroxy-L-tryptophan. ( Ashwal, S; Bodensteiner, J; Franz, D; Haas, RH; Huang, Y; Pranzatelli, MR; Tate, E, 1995) |
| "Six of them showed initial decrease of seizure frequency and severity and maintained improvement in some neurodevelopmental skills." | 1.72 | Monoamine neurotransmitters in early epileptic encephalopathies: New insights into pathophysiology and therapy. ( Aparicio, J; Artuch, R; Cortès-Saladelafont, E; Cuadras, D; Fons, C; García-Cazorla, À; Horvath, G; Juliá-Palacios, N; Molina-Anguita, C; Sigatulina Bondarenko, M, 2022) |
| "The degenerative type of progressive myoclonus epilepsy (PME) is a hereditary disease with grand mal seizures, stimulus sensitive myoclonus, characteristic EEG and mental deterioration in the late stage." | 1.26 | Decrease of GABA in the cerebrospinal fluid of patients with progressive myoclonus epilepsy and its correlation with the decrease of 5HIAA and HVA. ( Airaksinen, EM; Leino, E, 1982) |
| "The neurochemical basis of myoclonus responding to 5HT precursors and clonazepam is discussed." | 1.26 | Clinical, biochemical, and physiological features distinguishing myoclonus responsive to 5-hydroxytryptophan, tryptophan with a monoamine oxidase inhibitor, and clonazepam. ( Chadwick, D; Hallett, M; Harris, R; Jenner, P; Marsden, CD; Reynolds, EH, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (72.73) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Juliá-Palacios, N | 1 |
| Molina-Anguita, C | 1 |
| Sigatulina Bondarenko, M | 1 |
| Cortès-Saladelafont, E | 1 |
| Aparicio, J | 1 |
| Cuadras, D | 1 |
| Horvath, G | 1 |
| Fons, C | 1 |
| Artuch, R | 1 |
| García-Cazorla, À | 1 |
| Koskiniemi, ML | 2 |
| Leino, E | 3 |
| MacDonald, E | 2 |
| Airaksinen, MM | 2 |
| Riekkinen, PJ | 2 |
| Salo, H | 1 |
| Airaksinen, EM | 1 |
| Pranzatelli, MR | 2 |
| Tate, E | 2 |
| Huang, Y | 1 |
| Haas, RH | 1 |
| Bodensteiner, J | 1 |
| Ashwal, S | 1 |
| Franz, D | 2 |
| Martens, JM | 1 |
| Chadwick, D | 1 |
| Hallett, M | 1 |
| Harris, R | 1 |
| Jenner, P | 1 |
| Reynolds, EH | 1 |
| Marsden, CD | 1 |
| Kimiya, S | 1 |
| Seki, T | 1 |
| Maezawa, M | 1 |
| Yamada, T | 1 |
| Tachibana, Y | 1 |
| Koskiniemi, M | 1 |
| Laakso, J | 1 |
| Kuurne, T | 1 |
| Laipio, M | 1 |
| Härkönen, M | 1 |
2 trials available for hydroxyindoleacetic acid and Epilepsies, Myoclonic
| Article | Year |
|---|---|
L-tryptophan-carbidopa trial in patients with long-standing progressive myoclonus epilepsy.
Topics: Blood Platelets; Carbidopa; Clinical Trials as Topic; Drug Therapy, Combination; Epilepsies, Myoclon | 1981 |
Neuropharmacology of progressive myoclonus epilepsy: response to 5-hydroxy-L-tryptophan.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Carbidopa; Cross-Over Studies; Double-Blind Method; Drug The | 1995 |
9 other studies available for hydroxyindoleacetic acid and Epilepsies, Myoclonic
| Article | Year |
|---|---|
Monoamine neurotransmitters in early epileptic encephalopathies: New insights into pathophysiology and therapy.
Topics: Child, Preschool; Electroencephalography; Epilepsies, Myoclonic; Epilepsy; Female; Humans; Hydroxyin | 2022 |
Deficient intestinal absorption of L-tryptophan in progressive myoclonus epilepsy without Lafora bodies.
Topics: Epilepsies, Myoclonic; Female; Humans; Hydroxyindoleacetic Acid; Indican; Intestinal Absorption; Kin | 1980 |
Homovanillic acid and 5-hydroxyindoleacetic acid levels in cerebrospinal fluid of patients with progressive myoclonus epilepsy.
Topics: Adult; Brain; Epilepsies, Myoclonic; Female; Finland; Homovanillic Acid; Humans; Hydroxyindoleacetic | 1980 |
Decrease of GABA in the cerebrospinal fluid of patients with progressive myoclonus epilepsy and its correlation with the decrease of 5HIAA and HVA.
Topics: Adult; Epilepsies, Myoclonic; Female; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Hydroxyind | 1982 |
Buspirone in progressive myoclonus epilepsy.
Topics: Adolescent; Adult; Brain; Buspirone; Epilepsies, Myoclonic; Female; Humans; Hydroxyindoleacetic Acid | 1993 |
Clinical, biochemical, and physiological features distinguishing myoclonus responsive to 5-hydroxytryptophan, tryptophan with a monoamine oxidase inhibitor, and clonazepam.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Benzodiazepinones; Carbidopa; Child, Preschool; Clonaz | 1977 |
Baltic myoclonus.
Topics: Adolescent; Brain; Child; Electroencephalography; Epilepsies, Myoclonic; Humans; Hydroxyindoleacetic | 1986 |
Analysis of monamine metabolism in cerebrospinal fluid in childhood epilepsies.
Topics: Adolescent; Brain Damage, Chronic; Child; Child, Preschool; Epilepsies, Myoclonic; Epilepsy; Epileps | 1989 |
Indole levels in human lumbar and ventricular cerebrospinal fluid and the effect of L-tryptophan administration.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Anticonvulsants; Child; Chromatography, High Pressure | 1985 |