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hydroxyindoleacetic acid and Dyskinesia Syndromes

hydroxyindoleacetic acid has been researched along with Dyskinesia Syndromes in 45 studies

(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.

Research Excerpts

ExcerptRelevanceReference
"Ventricular fluid concentrations of homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA), the respective metabolites of dopamine and serotonin, were measured in 57 patients undergoing thalamotomy for relief of movement disorders."7.66Ventricular fluid homovanillic acid and 5-hydroxyindoleacetic acid concentrations in patients with movement disorders. ( Sharpless, NS; Tabaddor, K; Wolfson, LI, 1978)
"Two cases of severe dystonia and dyskinesia were treated with talipexole, a dopamine autoreceptor agonist, and the metabolites of dopamine, norepinephrine, and serotonin in cerebrospinal fluid (CSF) were determined."3.68Chronic treatment with talipexole dihydrochloride on abnormal involuntary movement in humans. ( Koga, I; Nishikawa, T; Tanaka, M; Tsuda, A; Uchida, Y; Yamada, S, 1990)
"Ventricular fluid concentrations of homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA), the respective metabolites of dopamine and serotonin, were measured in 57 patients undergoing thalamotomy for relief of movement disorders."3.66Ventricular fluid homovanillic acid and 5-hydroxyindoleacetic acid concentrations in patients with movement disorders. ( Sharpless, NS; Tabaddor, K; Wolfson, LI, 1978)
"We have studied the urinary excretion of 1,4-methylhistamine (1,4-MeHm), 5-hydroxyindole-3-acetic acid (5-HIAA) and homovanillic acid (HVA) in patients with Parkinson's disease, choreiform movements and essential tremor."3.65Urinary monoamine metabolite excretion in disorders of movement. Effects of amantadine and levodopa. ( Fleming, AM; Lenman, JA; Reid, A; Turnbull, MJ, 1977)
"Haloperidol is a classical neuroleptic drug that is still in use and can lead to abnormal motor activity such as tardive dyskinesia (TD) following repeated administration."1.35Protective effect of L-type calcium channel blockers against haloperidol-induced orofacial dyskinesia: a behavioural, biochemical and neurochemical study. ( Bishnoi, M; Chopra, K; Kulkarni, SK, 2008)
"Results of long-term administration of L-threo-3,4-dihydroxyphenylserine (L-DOPS), a synthetic precursor of noradrenaline, in a patient with freezing gait and pure akinesia are reported."1.30Result of long-term administration of L-threo-3,4-dihydroxyphenylserine in patients with pure akinesia as an early symptom of progressive supranuclear palsy. ( Fujii, S; Hatanaka, Y; Yamamoto, M, 1997)
"In contrast to senile dementia of Alzheimer's type SLI was not correlated with dementia scores but with motor disease progression."1.28Parkinson's disease and dementia: clinical and neurochemical correlations. ( Cramer, H; Strittmatter, MM, 1992)
"Harmalan induced clonic convulsions which were antagonized by diazepam."1.27Pharmacology of harmalan (1-methyl-3,4-dihydro-beta-carboline). ( Brüning, G; Hill, R; Nick, M; Rommelspacher, H; Susilo, R, 1985)
"Treatment with tetrabenazine did not significantly alter the metabolite levels in patients in whom it produced either improvement, or side effects."1.26CSF studies on the relationship between dopamine and 5-hydroxytryptamine in Parkinsonism and other movement disorders. ( Davidson, DL; Mawdsley, C; Pullar, IA; Wilson, H; Yates, CM, 1977)

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-199033 (73.33)18.7374
1990's8 (17.78)18.2507
2000's2 (4.44)29.6817
2010's2 (4.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Papandreou, A1
Rahman, S1
Fratter, C1
Ng, J1
Meyer, E1
Carr, LJ1
Champion, M1
Clarke, A1
Gissen, P1
Hemingway, C1
Hussain, N1
Jayawant, S1
King, MD1
Lynch, BJ1
Mewasingh, L1
Patel, J1
Prabhakar, P1
Neergheen, V1
Pope, S1
Heales, SJR1
Poulton, J1
Kurian, MA1
Creed, MC1
Hamani, C1
Bridgman, A1
Fletcher, PJ1
Nobrega, JN1
BOZZI, R1
BRUNO, A1
ALLEGRANZA, A1
Bishnoi, M1
Chopra, K1
Kulkarni, SK1
Jeste, DV1
Doongaji, DR1
Linnoila, M1
Kontur, PJ1
al-Tikriti, M1
Innis, RB1
Roth, RH1
Gil-Nagel, A1
Morlán, L1
Balseiro, J1
García de Yébenes, J1
Cabello, A1
Martínez-Martín, P1
Yamamoto, M2
Fujii, S1
Hatanaka, Y1
Fall, PA1
Ekman, R1
Granérus, AK1
Thorell, LH1
Wålinder, J1
Hyland, K1
Beaman, BL1
LeWitt, PA1
DeMaggio, AJ1
Klawans, H1
Tabaddor, K1
Wolfson, LI1
Sharpless, NS1
Wood, JH1
Davidson, DL1
Yates, CM1
Mawdsley, C1
Pullar, IA1
Wilson, H1
Rinne, UK1
Siirtola, T1
Sonninen, V1
Diukova, GM1
Bol'shakova, TD1
Rodshtat, IV1
Dibobes, GK1
Tiabenkova, VF1
Lenman, JA1
Turnbull, MJ1
Reid, A1
Fleming, AM1
Gerlach, J1
Thorsen, K1
Fog, R1
García Ruiz, PJ1
Mena, MA1
Peñafiel, N1
De Yébenes, JG1
Strittmatter, MM1
Cramer, H1
Nishikawa, T1
Yamada, S1
Tsuda, A1
Tanaka, M1
Koga, I1
Uchida, Y1
Tanii, H1
Hayashi, M1
Hashimoto, K1
Pagliusi, SR1
Löscher, W1
Ujike, H1
Ogawa, N1
Bradbury, AJ2
Costall, B2
Domeney, AM2
Testa, B1
Jenner, PG1
Marsden, CD3
Naylor, RJ2
Kitatani, T1
Hayashi, S1
Sakaguchi, T1
Jenner, PJ1
Jankovic, J1
Caskey, TC1
Stout, JT1
Butler, IJ1
Kostic, V1
Djuricic, B1
Paschen, W1
Rommelspacher, H1
Brüning, G1
Susilo, R1
Nick, M1
Hill, R1
Birkmayer, W1
Neumayer, E1
Messiha, FS1
Schnur, JA2
Chase, TN2
Brody, JA1
Papeschi, R1
Molina-Negro, P1
Sourkes, TL1
Erba, G1
Curzon, G2
Bazelon, M1
Barnet, A1
Lodge, A1
Shelburne, SA1
Pind, K1
Faurbye, A1
Cohen, DJ1
Shaywitz, BA1
Johnson, WT1
Bowers, M1
Sweet, RD1
McDowell, FH1
Guilleminault, C1
Tharp, BR1
Cousin, D1
Parkes, JD1
Rees, JE1
Kantamaneni, BD1
Knill-Jones, R1
Akbar, A1
Das, S1
Kataria, M1
Frankel, D1
Khanna, JM1
Kalant, H1
LeBlanc, AE1
Gordon, EK1
O'Reilly, S2
Loncin, M1
Cooksey, B2

Reviews

2 reviews available for hydroxyindoleacetic acid and Dyskinesia Syndromes

ArticleYear
Amine precursors in neurologic disorders and the psychoses.
    Research publications - Association for Research in Nervous and Mental Disease, 1975, Volume: 54

    Topics: Acetylcholine; Corpus Striatum; Dopamine; Homovanillic Acid; Humans; Huntington Disease; Hydroxyindo

1975
[Modern treatment of parkinsonism].
    Zeitschrift fur Neurologie, 1972, Volume: 202, Issue:4

    Topics: Antiparkinson Agents; Brain Stem; Dihydroxyphenylalanine; Dopamine; Drug Synergism; Female; Gastroin

1972

Trials

1 trial available for hydroxyindoleacetic acid and Dyskinesia Syndromes

ArticleYear
Extrapyramidal reactions and amine metabolites in cerebrospinal fluid during haloperidol and clozapine treatment of schizophrenic patients.
    Psychopharmacologia, 1975, Volume: 40, Issue:4

    Topics: Adult; Aged; Basal Ganglia Diseases; Clinical Trials as Topic; Clozapine; Dibenzazepines; Haloperido

1975

Other Studies

42 other studies available for hydroxyindoleacetic acid and Dyskinesia Syndromes

ArticleYear
Spectrum of movement disorders and neurotransmitter abnormalities in paediatric POLG disease.
    Journal of inherited metabolic disease, 2018, Volume: 41, Issue:6

    Topics: Adolescent; Child; Child, Preschool; DNA Polymerase gamma; Female; Homovanillic Acid; Humans; Hydrox

2018
Contribution of decreased serotonin release to the antidyskinetic effects of deep brain stimulation in a rodent model of tardive dyskinesia: comparison of the subthalamic and entopeduncular nuclei.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Jul-11, Volume: 32, Issue:28

    Topics: 5,7-Dihydroxytryptamine; Amphetamines; Analysis of Variance; Animals; Antipsychotic Agents; Autoradi

2012
URINARY METABOLITES OF SOME MONOAMINES AND CLINICAL EFFECTS UNDER RESERPINE AND CHLORPROMAZINE.
    The British journal of psychiatry : the journal of mental science, 1965, Volume: 111

    Topics: Autonomic Nervous System Diseases; Chlorpromazine; Drug Therapy; Extrapyramidal Tracts; Fluids and S

1965
Protective effect of L-type calcium channel blockers against haloperidol-induced orofacial dyskinesia: a behavioural, biochemical and neurochemical study.
    Neurochemical research, 2008, Volume: 33, Issue:9

    Topics: Animals; Antioxidants; Antipsychotic Agents; Behavior, Animal; Calcium Channel Blockers; Calcium Cha

2008
Elevated cerebrospinal fluid noradrenaline in tardive dyskinesia.
    The British journal of psychiatry : the journal of mental science, 1984, Volume: 144

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Antipsychotic Agents; Dyskinesia, Drug-Induced; Homovan

1984
Postmortem stability of monoamines, their metabolites, and receptor binding in rat brain regions.
    Journal of neurochemistry, 1994, Volume: 62, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Brain; Brain Chemistry; Dopamine; Huma

1994
[Neuro-acanthocytosis with associated myopathy. A case report].
    Neurologia (Barcelona, Spain), 1994, Volume: 9, Issue:4

    Topics: Acanthocytes; Adult; Basal Ganglia; Basophils; Brain Diseases; Cerebellum; Denervation; Homovanillic

1994
Result of long-term administration of L-threo-3,4-dihydroxyphenylserine in patients with pure akinesia as an early symptom of progressive supranuclear palsy.
    Clinical neuropharmacology, 1997, Volume: 20, Issue:4

    Topics: Antiparkinson Agents; Droxidopa; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol;

1997
ECT in Parkinson's disease. Changes in motor symptoms, monoamine metabolites and neuropeptides.
    Journal of neural transmission. Parkinson's disease and dementia section, 1995, Volume: 10, Issue:2-3

    Topics: Aged; Aged, 80 and over; Biogenic Monoamines; Electroconvulsive Therapy; Female; Homovanillic Acid;

1995
Monoamine changes in the brain of BALB/c mice following sub-lethal infection with Nocardia asteroides (GUH-2).
    Neurochemical research, 2000, Volume: 25, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Brain; Cerebellum; Dopamine; Female; H

2000
Ventricular fluid homovanillic acid and 5-hydroxyindoleacetic acid concentrations in patients with movement disorders.
    Neurology, 1978, Volume: 28, Issue:12

    Topics: Adult; Aged; Cerebral Palsy; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Middle A

1978
CSF HVA and 5-HIAA.
    Neurology, 1979, Volume: 29, Issue:6

    Topics: Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Movement Disorders; Phenylacetates

1979
CSF studies on the relationship between dopamine and 5-hydroxytryptamine in Parkinsonism and other movement disorders.
    Journal of neurology, neurosurgery, and psychiatry, 1977, Volume: 40, Issue:12

    Topics: Aged; Athetosis; Carbidopa; Chorea; Dihydroxyphenylalanine; Dopamine; Dystonia Musculorum Deformans;

1977
L-deprenyl treatment of on-off phenomena in Parkinson's disease.
    Journal of neural transmission, 1978, Volume: 43, Issue:3-4

    Topics: Aged; Benserazide; Dopamine; Drug Therapy, Combination; Female; Homovanillic Acid; Humans; Hydroxyin

1978
[Clinico-neurohumoral interrelationships in neuroses].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1978, Volume: 78, Issue:2

    Topics: 17-Hydroxycorticosteroids; Adrenal Cortex; Adult; Catecholamines; Chromaffin System; Female; Humans;

1978
Urinary monoamine metabolite excretion in disorders of movement. Effects of amantadine and levodopa.
    Journal of the neurological sciences, 1977, Volume: 32, Issue:2

    Topics: Amantadine; Chorea; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Methylhistamines;

1977
Cinnarizine-induced parkinsonism in primates.
    Clinical neuropharmacology, 1992, Volume: 15, Issue:2

    Topics: Animals; Biogenic Monoamines; Cinnarizine; Disease Models, Animal; Dopamine; Haplorhini; Homovanilli

1992
Parkinson's disease and dementia: clinical and neurochemical correlations.
    Neuroreport, 1992, Volume: 3, Issue:5

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic A

1992
Chronic treatment with talipexole dihydrochloride on abnormal involuntary movement in humans.
    Clinical neuropharmacology, 1990, Volume: 13, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Azepines; Dopamine Agents; Dystonia; Homovanillic Acid; Humans

1990
Behavioral syndrome induced by allylnitrile, crotononitrile or 2-pentenenitrile in rats.
    Neuropharmacology, 1991, Volume: 30, Issue:8

    Topics: Animals; Behavior, Animal; Brain; Cyproheptadine; Fenclonine; Hydroxyindoleacetic Acid; Male; Methys

1991
Development of tolerance to the wet-dog shake behaviour but not the increase in seizure threshold induced by L-5-hydroxytryptophan during continued treatment in rats.
    Psychopharmacology, 1985, Volume: 86, Issue:1-2

    Topics: 5-Hydroxytryptophan; Animals; Body Temperature; Body Weight; Brain Chemistry; Carbidopa; Drug Intera

1985
Effective treatment of pure akinesia with L-threo-3,4-dihydroxyphenylserine (DOPS): report of a case, with pharmacological considerations.
    Clinical neuropharmacology, 1985, Volume: 8, Issue:4

    Topics: Droxidopa; Electromyography; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydro

1985
The toxic actions of MPTP and its metabolite MPP+ are not mimicked by analogues of MPTP lacking an N-methyl moiety.
    Neuroscience letters, 1985, Oct-24, Volume: 61, Issue:1-2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic

1985
[Effects of pentoxifylline on 5-hydroxytryptamine in the mouse brain].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1985, Volume: 86, Issue:5

    Topics: 5-Hydroxytryptophan; Animals; Brain; Drug Interactions; Hydroxyindoleacetic Acid; Male; Mice; Mice,

1985
The neurotoxic actions of 6-hydroxydopamine infused into the rat substantia nigra.
    Neuroscience letters, 1986, Jun-18, Volume: 67, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic

1986
Lesch-Nyhan syndrome: a study of motor behavior and cerebrospinal fluid neurotransmitters.
    Annals of neurology, 1988, Volume: 23, Issue:5

    Topics: Carbidopa; Catecholamines; Child; Child, Preschool; Fluphenazine; Glycols; Homovanillic Acid; Humans

1988
Hemiballismus: changes in cerebrospinal fluid.
    Acta neurologica Scandinavica, 1988, Volume: 78, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Dominance, Cerebral; Dopamine; Female; Homovanillic Acid; Huma

1988
Pharmacology of harmalan (1-methyl-3,4-dihydro-beta-carboline).
    European journal of pharmacology, 1985, Mar-12, Volume: 109, Issue:3

    Topics: Animals; Behavior, Animal; Binding Sites; Carbolines; Cerebral Cortex; Convulsants; Female; Hydroxyi

1985
A study of biogenic amine metabolites in the cerebrospinal fluid and urine of monkeys with chlorpromazine-induced dyskinesia.
    Journal of the neurological sciences, 1974, Volume: 21, Issue:1

    Topics: 5-Methoxytryptamine; Animals; Biogenic Amines; Chlorpromazine; Dopamine; Epinephrine; Female; Haplor

1974
Parkinsonism-dementia of Guam: treatment with L-dopa.
    Neurology, 1971, Volume: 21, Issue:12

    Topics: Adult; Dementia; Dihydroxyphenylalanine; Drug Eruptions; Female; Humans; Hydroxyindoleacetic Acid; H

1971
The concentration of homovanillic and 5-hydroxyindoleacetic acids in ventricular and lumbar CSF. Studies in patients with extrapyramidal disorders, epilepsy, and other diseases.
    Neurology, 1972, Volume: 22, Issue:11

    Topics: Adolescent; Adult; Basal Ganglia Diseases; Cerebral Palsy; Cerebral Ventricles; Diazepam; Dihydroxyp

1972
Involuntary movements other than Parkinsonism: biochemical aspects.
    Proceedings of the Royal Society of Medicine, 1973, Volume: 66, Issue:9

    Topics: Acute Disease; Animals; Athetosis; Basal Ganglia; Brain; Dopamine; Fecal Incontinence; Homovanillic

1973
The effect of high doses of 5-hydroxytryptophan on a patient with trisomy 21. Clinical, chemical and EEG correlations.
    Brain research, 1968, Volume: 11, Issue:2

    Topics: 5-Hydroxytryptophan; Age Factors; Central Nervous System; Chromosomes, Human, 21-22 and Y; Down Synd

1968
Concentration of homovanillic acid and 5-hydroxyindoleacetic acid in the cerebrospinal fluid after treatment with probenecid in patients with drug-induced tardive dyskinesia.
    Acta psychiatrica Scandinavica, 1970, Volume: 46, Issue:4

    Topics: Dopamine; Humans; Hydroxyindoleacetic Acid; Movement Disorders; Phenylacetates; Probenecid; Schizoph

1970
Biogenic amines in autistic and atypical children. Cerebrospinal fluid measures of homovanillic acid and 5-hydroxyindoleacetic acid.
    Archives of general psychiatry, 1974, Volume: 31, Issue:6

    Topics: Autistic Disorder; Brain; Child; Child, Preschool; Diagnosis, Differential; Dopamine; Electroencepha

1974
Plasma dopa concentrations and the "on-off" effect after chronic treatment of Parkinson's disease.
    Neurology, 1974, Volume: 24, Issue:10

    Topics: Dietary Proteins; Dihydroxyphenylalanine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levod

1974
HVA and 5HIAA CSF measurements and 5HTP trials in some patients with involuntary movements.
    Journal of the neurological sciences, 1973, Volume: 18, Issue:4

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Chorea; Dopamine; Dystonia Musculorum Deformans; Femal

1973
Parkinson's disease, cerebral arteriosclerosis, and senile dementia. Clinical features and response to levodopa.
    The Quarterly journal of medicine, 1974, Volume: 43, Issue:169

    Topics: Aged; Dementia; Dihydroxyphenylalanine; Electroencephalography; Female; Gait; Homovanillic Acid; Hum

1974
Effect of acute and chronic ethanol administration on serotonin turnover in rat brain.
    Psychopharmacologia, 1974, Jun-21, Volume: 37, Issue:4

    Topics: Administration, Oral; Animals; Brain; Brain Chemistry; Drug Tolerance; Ethanol; Hydroxyindoleacetic

1974
Cerebrospinal fluid monoamine catabolites in drug-induced extrapyramidal disorders.
    Neuropharmacology, 1970, Volume: 9, Issue:3

    Topics: Amines; Brain; Chlorpromazine; Extrapyramidal Tracts; Female; Humans; Hydroxyindoleacetic Acid; Move

1970
Dopamine and basal ganglia disorders.
    Neurology, 1965, Volume: 15, Issue:11

    Topics: Adult; Basal Ganglia; Dopamine; Female; Hepatolenticular Degeneration; Humans; Hydroxyindoleacetic A

1965
The relationship between 5-hydroxyindoles and catecholamines.
    Neurology, 1965, Volume: 15, Issue:12

    Topics: Blood-Brain Barrier; Brain Chemistry; Brain Diseases; Catecholamines; Dopamine; Female; Humans; Hydr

1965