hydroxyindoleacetic acid has been researched along with Dyskinesia, Drug-Induced in 27 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
Dyskinesia, Drug-Induced: Abnormal movements, including HYPERKINESIS; HYPOKINESIA; TREMOR; and DYSTONIA, associated with the use of certain medications or drugs. Muscles of the face, trunk, neck, and extremities are most commonly affected. Tardive dyskinesia refers to abnormal hyperkinetic movements of the muscles of the face, tongue, and neck associated with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS). (Adams et al., Principles of Neurology, 6th ed, p1199)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Interest in serotonergic involvement in Parkinson's disease (PD) has focussed recently on the possibility that the remaining serotonin neurons innervating striatum (caudate and putamen) might release dopamine as a 'false transmitter'--an action that could have both beneficial and harmful (e." | 1.35 | Preferential loss of serotonin markers in caudate versus putamen in Parkinson's disease. ( Chang, LJ; Furukawa, Y; Guttman, M; Hornykiewicz, O; Kish, SJ; Rajput, A; Tong, J, 2008) |
| "Rats treated with haloperidol at a dose of 1 mg/kg twice a day for 2 weeks displayed VCMs with twitching of facial musculature that increased in a time dependent manner as the treatment continued to 5 weeks." | 1.34 | Reversal of haloperidol-induced tardive vacuous chewing movements and supersensitive somatodendritic serotonergic response by buspirone in rats. ( Haleem, DJ; Haleem, MA; Samad, N, 2007) |
| "Present study was designed to monitor the responsiveness of 5HT (5-Hydroxytryptamine) -2C receptors following the long-term administration of haloperidol in rats." | 1.34 | Neurochemical and behavioral effects of m-CPP in a rat model of tardive dyskinesia. ( Haleem, DJ; Ikram, H; Samad, N, 2007) |
| " Pretreatment with 5,7-dihydroxytryptamine (5,7-DHT) suppressed the allylnitrile-induced head twitching, and decreased the contents of 5-HT and 5-HIAA in almost all areas of the brain throughout the observation period, as well as the ratio of 5-HIAA/5-HT in the medulla oblongata plus pons from 1 to 30 days after dosing with allylnitrile." | 1.29 | Involvement of noradrenergic and 5-hydroxytryptaminergic systems in allylnitrile-induced head twitching. ( Hashimoto, K; Huang, J; Tanii, H, 1993) |
| "Rats treated with anisomycin alone also showed significant increases in striatal 5-HT and 5-HIAA concentrations which were somewhat higher on the side of the ICV infusions." | 1.28 | The protein synthesis inhibitor, anisomycin, causes exacerbation of the iminodipropionitrile-induced spasmodic dyskinetic syndrome in rats. ( Cadet, JL; Fahn, S; Jackson-Lewis, V; Katz, M; Stennett, R, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (55.56) | 18.7374 |
| 1990's | 6 (22.22) | 18.2507 |
| 2000's | 6 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dupre, KB | 2 |
| Eskow, KL | 2 |
| Steiniger, A | 1 |
| Klioueva, A | 1 |
| Negron, GE | 1 |
| Lormand, L | 1 |
| Park, JY | 2 |
| Bishop, C | 3 |
| Barnum, CJ | 1 |
| Dickinson, SO | 1 |
| Taylor, JL | 1 |
| Walker, PD | 1 |
| Haleem, DJ | 2 |
| Samad, N | 2 |
| Haleem, MA | 1 |
| Ikram, H | 1 |
| Kish, SJ | 1 |
| Tong, J | 1 |
| Hornykiewicz, O | 1 |
| Rajput, A | 1 |
| Chang, LJ | 1 |
| Guttman, M | 1 |
| Furukawa, Y | 1 |
| Ogawa, T | 1 |
| Nagao, T | 3 |
| Kashiwabara, K | 1 |
| Fujiwara, Y | 1 |
| Harada, T | 1 |
| Otsuki, S | 3 |
| Jeste, DV | 2 |
| Doongaji, DR | 1 |
| Linnoila, M | 1 |
| Akiyama, K | 1 |
| Yamamoto, M | 1 |
| Fujimoto, A | 1 |
| Ebara, T | 1 |
| Sato, M | 2 |
| Tanii, H | 2 |
| Huang, J | 1 |
| Hashimoto, K | 2 |
| Szymanski, S | 1 |
| Lieberman, J | 2 |
| Pollack, S | 2 |
| Munne, R | 1 |
| Safferman, A | 1 |
| Kane, J | 2 |
| Kronig, M | 1 |
| Cooper, T | 2 |
| Fornai, F | 1 |
| Alessandri, MG | 1 |
| Saginario, A | 1 |
| Vaglini, F | 1 |
| Corsini, GU | 1 |
| Winsberg, BG | 2 |
| Hurwic, MJ | 2 |
| Perel, J | 1 |
| Sverd, J | 1 |
| Klutch, A | 1 |
| Roccatagliata, G | 2 |
| Albano, C | 2 |
| Besio, G | 1 |
| Ohshimo, T | 1 |
| Mitsunobu, K | 1 |
| Cocito, L | 1 |
| Maffini, M | 1 |
| Bowers, MB | 1 |
| Moore, D | 1 |
| Tarsy, D | 1 |
| Lohr, JB | 1 |
| Kuczenski, R | 1 |
| Bracha, HS | 1 |
| Moir, M | 1 |
| Bankiewicz, KS | 1 |
| Plunkett, RJ | 1 |
| Mefford, I | 1 |
| Kopin, IJ | 1 |
| Oldfield, EH | 1 |
| Okayama, A | 1 |
| Yamatodani, A | 1 |
| Hayashi, M | 1 |
| Saito, T | 1 |
| Ishizawa, H | 1 |
| Tsuchiya, F | 1 |
| Ozawa, H | 1 |
| Takahata, N | 1 |
| Cadet, JL | 2 |
| Jackson-Lewis, V | 2 |
| Fahn, S | 2 |
| Lu, RB | 1 |
| Ko, HC | 1 |
| Lin, WL | 1 |
| Lin, YT | 1 |
| Ho, SL | 1 |
| Stennett, R | 1 |
| Katz, M | 1 |
| Johns, C | 1 |
| Stahl, SM | 1 |
| Faull, KF | 1 |
| Barchas, JD | 1 |
| Berger, PA | 1 |
3 trials available for hydroxyindoleacetic acid and Dyskinesia, Drug-Induced
| Article | Year |
|---|---|
CSF monoamine metabolism in patients with tardive dyskinesia: effect of oxypertine and hydroxyzine pamoate.
Topics: Biogenic Amines; Clinical Trials as Topic; Cyclic AMP; Cyclic GMP; Dyskinesia, Drug-Induced; Female; | 1983 |
The dopamine-serotonin relationship in clozapine response.
Topics: Adolescent; Adult; Antipsychotic Agents; Clozapine; Dopamine; Drug Resistance; Dyskinesia, Drug-Indu | 1993 |
Tardive dyskinesia: a clinical test of the supersensitivity hypothesis.
Topics: Adult; Aged; Clinical Trials as Topic; Cyclic AMP; Depression; Dyskinesia, Drug-Induced; Female; Hom | 1979 |
24 other studies available for hydroxyindoleacetic acid and Dyskinesia, Drug-Induced
| Article | Year |
|---|---|
Effects of coincident 5-HT1A receptor stimulation and NMDA receptor antagonism on L-DOPA-induced dyskinesia and rotational behaviors in the hemi-parkinsonian rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Corpus Striatum; Di | 2008 |
The role of the dorsal raphe nucleus in the development, expression, and treatment of L-dopa-induced dyskinesia in hemiparkinsonian rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Dyskinesia, Drug-Induced; Hydrox | 2009 |
Dopamine D1 and D2 receptor contributions to L-DOPA-induced dyskinesia in the dopamine-depleted rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Behavior, Animal; Benzazepines; Corpu | 2005 |
Reversal of haloperidol-induced tardive vacuous chewing movements and supersensitive somatodendritic serotonergic response by buspirone in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Buspirone; Chromatography, Hi | 2007 |
Neurochemical and behavioral effects of m-CPP in a rat model of tardive dyskinesia.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Chromatography, High Pressure Liquid; Corpus Striat | 2007 |
Preferential loss of serotonin markers in caudate versus putamen in Parkinson's disease.
Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Caudate Nucleus; Dopamine; Dyskinesia, Drug-Induced; | 2008 |
Tardive dyskinesia and neurotransmitters: effects of sodium valproate, cyproheptadine, oxypertine, hydroxyzine pamoate and Ca-hopantenate on monoamine metabolites, cyclic nucleotides and gamma-aminobutyric acid in human cerebrospinal fluid.
Topics: Adult; Aged; Cyclic AMP; Cyclic GMP; Cyproheptadine; Dyskinesia, Drug-Induced; Female; Homovanillic | 1984 |
Elevated cerebrospinal fluid noradrenaline in tardive dyskinesia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Antipsychotic Agents; Dyskinesia, Drug-Induced; Homovan | 1984 |
Involvement of noradrenergic and 5-hydroxytryptaminergic systems in allylnitrile-induced head twitching.
Topics: 5,7-Dihydroxytryptamine; Animals; Benzylamines; Dyskinesia, Drug-Induced; Head; Hydroxyindoleacetic | 1993 |
beta,beta'-Iminodipropionitrile-induced persistent dyskinetic syndrome in mice is transiently modified by MPTP.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Behavior, Animal; Biogenic Monoamines; Cerebr | 1993 |
Neurochemistry of withdrawal emergent symptoms in children.
Topics: Antipsychotic Agents; Child; Cyclic AMP; Dyskinesia, Drug-Induced; Homovanillic Acid; Humans; Hydrox | 1977 |
Neurochemistry of withdrawal emergent symptoms in children.
Topics: Antipsychotic Agents; Child; Child, Preschool; Dyskinesia, Drug-Induced; Female; Homovanillic Acid; | 1978 |
[Late chronic dyskinesia from neuroleptic drugs (CSF and pharmacological data) (author's transl)].
Topics: Adult; Antipsychotic Agents; Brain; Dopamine; Dyskinesia, Drug-Induced; Female; Homovanillic Acid; H | 1978 |
Cerebrospinal fluid monoamine metabolites and cyclic nucleotides in chronic schizophrenic patients with tardive dyskinesia or drug-induced tremor.
Topics: Adult; Chronic Disease; Cyclic AMP; Cyclic GMP; Cyproheptadine; Dyskinesia, Drug-Induced; Female; Ho | 1979 |
Interactions between central monoaminergic systems: dopamine-serotonin.
Topics: Adolescent; Adult; Aged; Bipolar Disorder; Depression; Dopamine; Dyskinesia, Drug-Induced; Female; H | 1979 |
Increased indices of free radical activity in the cerebrospinal fluid of patients with tardive dyskinesia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Antipsychotic Agents; Dyskinesia, Drug-Induced; Female; | 1990 |
Behavioral recovery from MPTP-induced parkinsonism in monkeys after intracerebral tissue implants is not related to CSF concentrations of dopamine metabolites.
Topics: Adrenal Medulla; Amnion; Animals; Brain Tissue Transplantation; Caudate Nucleus; Disease Models, Ani | 1990 |
Alterations in the metabolism of serotonin and dopamine in the mouse brain following a single administration of allylnitrile, which induces long-term dyskinesia.
Topics: Administration, Oral; Animals; Brain; Chromatography, High Pressure Liquid; Dopamine; Dyskinesia, Dr | 1991 |
Neurochemical findings in the cerebrospinal fluid of schizophrenic patients with tardive dyskinesia and neuroleptic-induced parkinsonism.
Topics: Adult; Aged; Antipsychotic Agents; Catecholamines; Dopamine; Dyskinesia, Drug-Induced; Epinephrine; | 1986 |
The iminodipropionitrile (IDPN) model of persistent spasmodic dyskinesias: regional serotonin metabolism in rat brain.
Topics: Animals; Brain; Brain Stem; Corpus Striatum; Disease Models, Animal; Dyskinesia, Drug-Induced; Hydro | 1988 |
CSF neurochemical study of tardive dyskinesia.
Topics: Acetylcholinesterase; Dyskinesia, Drug-Induced; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; | 1989 |
The protein synthesis inhibitor, anisomycin, causes exacerbation of the iminodipropionitrile-induced spasmodic dyskinetic syndrome in rats.
Topics: Animals; Anisomycin; Corpus Striatum; Drug Interactions; Dyskinesia, Drug-Induced; Hydroxyindoleacet | 1989 |
Clozapine pharmacology and tardive dyskinesia.
Topics: Adolescent; Adult; Clozapine; Dibenzazepines; Dyskinesia, Drug-Induced; Epinephrine; Female; Homovan | 1989 |
CSF monamine metabolites in movement disorders and normal aging.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Dyskinesia, Drug-Induced; Dystonia; Female; Glycols; Ho | 1985 |