hydroxyindoleacetic acid has been researched along with Deficiency, Mental in 28 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a patient with the Lesch-Nyhan syndrome we found decreased spinal fluid 5-hydroxyindole acetic acid (5-HIAA), the major metabolite of serotonin, and decreased homovanillic acid (HVA), the major metabolite of dopamine, indicating a decrease in monoamine metabolism." | 7.66 | Effects of L-5-hydroxytryptophan on monoamine and amino acids turnover in the Lesch-Nyhan syndrome. ( Castells, S; Chakrabarti, C; Hurwic, M; Nyhan, WL; Perel, JM; Winsberg, BG, 1979) |
| "In 8 cases of typical neuroleptic malignant syndrome (NMS), homovanillic acid (HVA), 5-hydroxyindole acetic acid (5-HIAA), noradrenaline (NA), and 3-methoxy-4-hydroxyphenylethyleneglycol (MHPG) levels in the cerebrospinal fluid (CSF) were assayed during both the active phase of NMS and after recovery." | 3.68 | Neuroleptic malignant syndrome: a study of CSF monoamine metabolism. ( Ishiguro, T; Nisijima, K, 1990) |
| "In a patient with the Lesch-Nyhan syndrome we found decreased spinal fluid 5-hydroxyindole acetic acid (5-HIAA), the major metabolite of serotonin, and decreased homovanillic acid (HVA), the major metabolite of dopamine, indicating a decrease in monoamine metabolism." | 3.66 | Effects of L-5-hydroxytryptophan on monoamine and amino acids turnover in the Lesch-Nyhan syndrome. ( Castells, S; Chakrabarti, C; Hurwic, M; Nyhan, WL; Perel, JM; Winsberg, BG, 1979) |
| "All AADCD patients were affected by intellectual disability and psychiatric disorders." | 1.72 | Long-term neurological and psychiatric outcomes in patients with aromatic l-amino acid decarboxylase deficiency. ( Battini, R; Carducci, C; Fusco, C; Leuzzi, V; Manti, F; Mastrangelo, M; Spagnoli, C; Tolve, M, 2022) |
| "The Fragile X syndrome, a common form of mental retardation in humans, is caused by silencing the fragile X mental retardation (FMR1) gene leading to the absence of the encoded fragile X mental retardation protein 1 (FMRP)." | 1.31 | Alterations of amino acids and monoamine metabolism in male Fmr1 knockout mice: a putative animal model of the human fragile X mental retardation syndrome. ( Braun, K; Gruss, M, 2001) |
| "In the group of 9 children with other psychoses, both the level of homovanillic acid and that of 5-hydroxy-indoleacetic acid was raised." | 1.27 | Childhood psychosis and monoamine metabolites in spinal fluid. ( Gillberg, C; Hamilton-Hellberg, C; Svennerholm, L, 1983) |
| "It is postulated that the seizures and neurological deterioration of the patient were related to a deficiency in the synthesis of biogenic amine neurotransmitters." | 1.26 | Biogenic amine synthesis defect in dihydropteridine reductase deficiency. ( Butler, IJ; Koslow, SH, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (78.57) | 18.7374 |
| 1990's | 3 (10.71) | 18.2507 |
| 2000's | 2 (7.14) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (3.57) | 2.80 |
| Authors | Studies |
|---|---|
| Manti, F | 1 |
| Mastrangelo, M | 1 |
| Battini, R | 1 |
| Carducci, C | 2 |
| Spagnoli, C | 1 |
| Fusco, C | 1 |
| Tolve, M | 1 |
| Leuzzi, V | 1 |
| VALCOURT, AJ | 1 |
| HSIA, DY | 1 |
| ROWLEY, WA | 1 |
| HUANG, I | 1 |
| Gibson, KM | 1 |
| Gupta, M | 1 |
| Pearl, PL | 1 |
| Tuchman, M | 1 |
| Vezina, LG | 1 |
| Snead, OC | 1 |
| Smit, LM | 1 |
| Jakobs, C | 1 |
| Madej, A | 1 |
| Pakszys, W | 1 |
| Gillberg, C | 1 |
| Svennerholm, L | 1 |
| Hamilton-Hellberg, C | 1 |
| Gruss, M | 1 |
| Braun, K | 1 |
| Koslow, SH | 1 |
| Butler, IJ | 1 |
| Castells, S | 1 |
| Chakrabarti, C | 1 |
| Winsberg, BG | 1 |
| Hurwic, M | 1 |
| Perel, JM | 1 |
| Nyhan, WL | 1 |
| Martsinkevich, NE | 1 |
| Pozdeev, VK | 1 |
| Hanley, HG | 1 |
| Stahl, SM | 1 |
| Freedman, DX | 1 |
| Ritvo, ER | 1 |
| Greenberg, AS | 1 |
| Coleman, M | 1 |
| Martineau, J | 1 |
| Barthélémy, C | 1 |
| Jouve, J | 1 |
| Muh, JP | 1 |
| Lelord, G | 1 |
| Nisijima, K | 1 |
| Ishiguro, T | 1 |
| Zeman, J | 1 |
| Böswart, J | 1 |
| Percy, AK | 1 |
| Zoghbi, H | 1 |
| Riccardi, VM | 1 |
| Nalini, K | 1 |
| Aroor, AR | 1 |
| Rao, A | 1 |
| Bettschart, W | 1 |
| Broché, JP | 1 |
| Tissot, R | 1 |
| Pare, CM | 1 |
| Dubowitz, V | 1 |
| Rogers, KJ | 1 |
| Partington, MW | 3 |
| MacDonald, MR | 1 |
| Tu, J | 1 |
| Airaksinen, EM | 1 |
| Kauko, K | 1 |
| Himwich, WA | 1 |
| Fukuyama, GS | 1 |
| Tu, JB | 1 |
| Wong, CY | 1 |
| Lozzio, CB | 1 |
| Jauregui, GR | 1 |
| Scornavachi, JC | 1 |
| Gambin, MA | 1 |
| Pscheidt, GR | 1 |
| Berlet, HH | 1 |
| Spaide, J | 1 |
| Himwich, HE | 1 |
2 trials available for hydroxyindoleacetic acid and Deficiency, Mental
| Article | Year |
|---|---|
[Correlation of the clinical and pharmaco-dynamic effects of Niamid in the treatment of severely mentally retarded children].
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Child; Clinical Trials as Topic; Down Syndrome; Female; Huma | 1965 |
5-hydroxytryptophan (5-HTP) in Down's syndrome.
Topics: 5-Hydroxytryptophan; Child; Child, Preschool; Clinical Trials as Topic; Down Syndrome; Female; Human | 1971 |
26 other studies available for hydroxyindoleacetic acid and Deficiency, Mental
| Article | Year |
|---|---|
Long-term neurological and psychiatric outcomes in patients with aromatic l-amino acid decarboxylase deficiency.
Topics: Adolescent; Adult; Amino Acids; Aromatic-L-Amino-Acid Decarboxylases; Biogenic Amines; Child; Dopami | 2022 |
Study of excretion of 5-hydroxyindoleacetic acid in mental patients.
Topics: Biological Transport; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Intellectual Disability; | 1959 |
The excretion of 5-hydroxyindoleacetic acid in the heterozygous carrier for phenylketonuria.
Topics: Biological Transport; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Intellectual Disability; | 1961 |
Significant behavioral disturbances in succinic semialdehyde dehydrogenase (SSADH) deficiency (gamma-hydroxybutyric aciduria).
Topics: Adult; Aldehyde Oxidoreductases; Atrophy; Cerebellum; Chromatography, High Pressure Liquid; Chromato | 2003 |
Psychic and motor functions and serotonin (5 HT) metabolism in brain-damaged children before and after administration of Niamid and Raupasil.
Topics: Adolescent; Brain Damage, Chronic; Child; Child Behavior Disorders; Female; Humans; Hydroxyindoleace | 1967 |
Childhood psychosis and monoamine metabolites in spinal fluid.
Topics: Adolescent; Age Factors; Autistic Disorder; Brain Diseases; Cerebral Palsy; Child; Child, Preschool; | 1983 |
Alterations of amino acids and monoamine metabolism in male Fmr1 knockout mice: a putative animal model of the human fragile X mental retardation syndrome.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Brain St | 2001 |
Biogenic amine synthesis defect in dihydropteridine reductase deficiency.
Topics: 5-Hydroxytryptophan; Biogenic Amines; Carbidopa; Dopamine; Homovanillic Acid; Humans; Hydroxyindolea | 1977 |
Effects of L-5-hydroxytryptophan on monoamine and amino acids turnover in the Lesch-Nyhan syndrome.
Topics: 5-Hydroxytryptophan; Amino Acids; Carbidopa; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleaceti | 1979 |
[Serotonin metabolism in children with different forms of oligophrenia].
Topics: Child; Humans; Hydroxyindoleacetic Acid; Intellectual Disability; Reserpine; Serotonin | 1977 |
Hyperserotonemia and amine metabolites in autistic and retarded children.
Topics: Adolescent; Adult; Age Factors; Autistic Disorder; Child; Child, Institutionalized; Child, Preschool | 1977 |
Biochemical studies of children with the syndromes of autism, childhood schizophrenia and related developmental disabilities: a review.
Topics: Autistic Disorder; Blood Platelets; Brain; Bufotenin; Child; Dopamine beta-Hydroxylase; Homovanillic | 1977 |
Depressed 5-hydroxyindole levels associated with hyperactive and aggressive behavior. Relationship to drug response.
Topics: Adolescent; Adult; Aggression; Child; Humans; Hydroxyindoleacetic Acid; Hyperkinesis; Intellectual D | 1976 |
Monoamines (serotonin and catecholamines) and their derivatives in infantile autism: age-related changes and drug effects.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Autistic Disorder; Catecholamines; Child; Child Develop | 1992 |
Neuroleptic malignant syndrome: a study of CSF monoamine metabolism.
Topics: Adult; Biogenic Monoamines; Bipolar Disorder; Depressive Disorder; Female; Homovanillic Acid; Humans | 1990 |
[Metabolites of neurotransmitters in the cerebrospinal fluid in children].
Topics: Adolescent; Child; Child, Preschool; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; In | 1991 |
Rett syndrome: initial experience with an emerging clinical entity.
Topics: Adolescent; Biopsy; Child; Child Development; Child, Preschool; Electroencephalography; Female; Homo | 1985 |
Urinary levels of biogenic amine metabolites in mentally retarded children.
Topics: Adolescent; Biogenic Amines; Child; Creatinine; Female; Homovanillic Acid; Humans; Hydroxyindoleacet | 1988 |
5-hydroxyindoles in phenylketonuric and nonphenylketonuric mental defectives.
Topics: 5-Hydroxytryptophan; Animals; Biological Transport; Carboxy-Lyases; Child; Down Syndrome; Humans; Hy | 1968 |
5-hydroxyindoles in the cerebrospinal fluid of infants with Down's syndrome and muscle hypotonia.
Topics: Child; Child, Preschool; Down Syndrome; Female; Humans; Hydroxyindoleacetic Acid; Infant; Intellectu | 1969 |
5-hydroxyindole levels in the blood and CSF in Down's syndrome, phenylketonuria and severe mental retardation.
Topics: Adolescent; Adult; Child; Child, Preschool; Down Syndrome; Female; Humans; Hydroxyindoleacetic Acid; | 1972 |
Effect of probenecid on 5-hydroxyindoles in cerebrospinal fluid in Down's syndrome.
Topics: Administration, Oral; Adolescent; Child; Chromatography, Gel; Depression, Chemical; Down Syndrome; F | 1973 |
Genral neurophysiology (biochemical aspects).
Topics: Age Factors; Animals; Bipolar Disorder; Blood-Brain Barrier; Brain; Brain Diseases; Cerebrovascular | 1971 |
Blood serotonin levels in severe mental retardation.
Topics: Age Factors; Blood Pressure; Child; Child, Preschool; Defecation; Diazepam; Diet; Female; Humans; Hy | 1973 |
Chromosome mosaicism in a mentally retarded mother and her daughter.
Topics: Adolescent; Adult; Chromosomes, Human, 21-22 and Y; Female; Humans; Hydroxyindoleacetic Acid; Hypert | 1967 |
Variations of urinary creatinine and its correlation to excretion of indole metabolites in mental patients.
Topics: Chemistry, Clinical; Circadian Rhythm; Creatine; Humans; Hydroxyindoleacetic Acid; In Vitro Techniqu | 1966 |