hydroxyindoleacetic acid has been researched along with Coma in 14 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
Coma: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Of five comatose patients, two had cerebrovascular lesions and three had sustained head injury, and, in four of the five, the values of either one or both of HVA and 5-HIAA were low, but in the fifth case the 5-HIAA value was high." | 5.26 | Homovanillic acid and 5-hydroxyindoleacetic acid in the ventricular CSF of comatose patients with obstructive hydrocephalus. ( Inagawa, T; Ishikawa, S; Uozumi, T, 1980) |
| "The main metabolites of noradrenaline, serotonin, and dopamine, methoxyhydroxyphenylglycol (MHPG), 5-hydroxyindole-acetic acid (5HIAA), and homovanillic acid (HVA), respectively, were assessed in CSF samples of patients in coma after severe head injury, the first days after the accident and again after an improvement (13 patients) or deterioration (7 patients) in their clinical state, evaluated by the score on the Glasgow Coma Scale." | 3.69 | CSF neurotransmitter metabolites in comatose head injury patients during changes in their clinical state. ( Christopoulos, M; Kotsou, A; Markianos, M; Seretis, A, 1996) |
| "The main metabolites of the neurotransmitters noradrenaline, dopamine, and serotonin, methoxy-hydroxyphenylglycol (MHPG), homovanillic acid (HVA), and 5-hydroxyindoleacetic acid (5HIAA) respectively, were estimated by HPLC with electrochemical detection in CSF samples from 24 patients in coma after head injury, 1 to 12 (mean 3." | 3.68 | CSF neurotransmitter metabolites and short-term outcome of patients in coma after head injury. ( Baltas, I; Kotsou, S; Markianos, M; Sacharogiannis, H; Seretis, A, 1992) |
| "Tyrosine (Tyr), tyrosine hydroxylase (TH), tryptophan (Trp), serotonin (5-HT), and 5-hydroxyindole acetic acid (5-HIAA) were assayed spectrofluorometrically and radioenzymatically in various regions of post-mortem brains of human patients with hepatic, uremic, and diabetic coma, liver cirrhosis without coma, and hepatic coma treated with parenteral administration of L-valine, a branched-chain amino acid." | 3.66 | Brain monoamines in hepatic encephalopathy and other types of metabolic coma. ( Jellinger, K; Kothbauer, P; Rausch, WD; Riederer, P, 1978) |
| "The concentrations of homovanillic acid (HVA), 3-methoxy, 4-hydroxyphenylglycol (MHPG), and 5-hydroxyindolylacetic acid (5-HIAA) were measured in samples of ventricular cerebrospinal fluid (CSF) taken from 15 patients who were comatose as a result of an acute head injury, a tumour, or a cerebrovascular accident." | 3.66 | Amine metabolites in ventricular cerebrospinal fluid in coma. ( Tsementzis, SA; Wilson, H; Yates, CM, 1979) |
| "Of five comatose patients, two had cerebrovascular lesions and three had sustained head injury, and, in four of the five, the values of either one or both of HVA and 5-HIAA were low, but in the fifth case the 5-HIAA value was high." | 1.26 | Homovanillic acid and 5-hydroxyindoleacetic acid in the ventricular CSF of comatose patients with obstructive hydrocephalus. ( Inagawa, T; Ishikawa, S; Uozumi, T, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (78.57) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Inagawa, T | 1 |
| Ishikawa, S | 1 |
| Uozumi, T | 1 |
| Batshaw, ML | 1 |
| Robinson, MB | 1 |
| Hyland, K | 1 |
| Djali, S | 1 |
| Heyes, MP | 1 |
| Markianos, M | 2 |
| Seretis, A | 2 |
| Kotsou, A | 1 |
| Christopoulos, M | 1 |
| Riederer, P | 5 |
| Kleinberger, G | 2 |
| Rausch, WD | 2 |
| Jellinger, K | 5 |
| Wuketich, S | 2 |
| Kothbauer, P | 2 |
| Yates, CM | 1 |
| Tsementzis, SA | 1 |
| Wilson, H | 1 |
| Livrea, P | 1 |
| Di Reda, N | 1 |
| De Blasi, A | 1 |
| Bertolino, A | 1 |
| Bareggi, SR | 1 |
| Porta, M | 1 |
| Selenati, A | 1 |
| Assael, BM | 1 |
| Calderini, G | 1 |
| Collice, M | 1 |
| Rossanda, M | 1 |
| Morselli, PL | 1 |
| Kotsou, S | 1 |
| Baltas, I | 1 |
| Sacharogiannis, H | 1 |
| O'Shanick, GJ | 1 |
| Artru, F | 1 |
| Gagnieu, MC | 1 |
| Jourdan, C | 1 |
| Quincy, C | 1 |
| Renaud, B | 1 |
| Deleuze, R | 1 |
1 review available for hydroxyindoleacetic acid and Coma
| Article | Year |
|---|---|
Neuropsychiatric complications in head injury.
Topics: Amnesia; Attention; Brain; Brain Chemistry; Cognition; Coma; Craniocerebral Trauma; Electroencephalo | 1986 |
13 other studies available for hydroxyindoleacetic acid and Coma
| Article | Year |
|---|---|
Homovanillic acid and 5-hydroxyindoleacetic acid in the ventricular CSF of comatose patients with obstructive hydrocephalus.
Topics: Adolescent; Adult; Brain Diseases; Brain Neoplasms; Child; Coma; Craniopharyngioma; Ependymoma; Fema | 1980 |
Quinolinic acid in children with congenital hyperammonemia.
Topics: Ammonia; Biogenic Amines; Biopterins; Child, Preschool; Coma; Humans; Hydroxyindoleacetic Acid; Infa | 1993 |
CSF neurotransmitter metabolites in comatose head injury patients during changes in their clinical state.
Topics: Adolescent; Adult; Aged; Brain Damage, Chronic; Brain Injuries; Coma; Female; Homovanillic Acid; Hum | 1996 |
[Metabolic factors in the pathogenesis of consciousness disorders and coma].
Topics: Aged; Brain; Coma; Diabetic Coma; Dopamine; Hepatic Encephalopathy; Humans; Hydroxyindoleacetic Acid | 1979 |
Brain monoamines in hepatic encephalopathy and other types of metabolic coma.
Topics: Aged; Animals; Brain; Coma; Diabetic Coma; Female; Hepatic Encephalopathy; Humans; Hydroxyindoleacet | 1978 |
Amine metabolites in ventricular cerebrospinal fluid in coma.
Topics: Adolescent; Adult; Brain Injuries; Brain Neoplasms; Cerebrospinal Fluid Proteins; Cerebrovascular Di | 1979 |
Brain monoamines in human hepatic encephalopathy.
Topics: Aged; Brain Chemistry; Brain Stem; Coma; Diabetic Coma; Dopamine; Hepatic Encephalopathy; Humans; Hy | 1978 |
Brain monoamines in metabolic coma and stroke.
Topics: Acute Disease; Aged; Biogenic Amines; Brain Chemistry; Coma; Diabetic Coma; Dopamine; Female; gamma- | 1978 |
Homovanillic acid and 5-hydroxyindoleacetic acid in human brain areas at autopsy. Effect of pre-death conditions with special attention to the state of consciousness and metabolic diseases.
Topics: Adult; Aged; Brain Chemistry; Coma; Diabetic Coma; Hepatic Encephalopathy; Homovanillic Acid; Humans | 1978 |
Brain monoamines in metabolic (endotoxic) coma. A preliminary biochemical study in human postmortem material.
Topics: Aged; Brain Chemistry; Coma; Dopamine; Female; Hepatic Encephalopathy; Humans; Hydroxyindoleacetic A | 1977 |
Homovanillic acid and 5-hydroxyindole-acetic acid in the csf of patients after a severe head injury. I. Lumbar csf concentration in chronic brain post-traumatic syndromes.
Topics: Adolescent; Adult; Brain Damage, Chronic; Child; Child, Preschool; Coma; Female; Homovanillic Acid; | 1975 |
CSF neurotransmitter metabolites and short-term outcome of patients in coma after head injury.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Brain Damage, Chronic; Coma; Female; Glasgow Coma Sca | 1992 |
[Exploration of the metabolism of brain serotonin and dopamine in prolonged traumatic coma:prognostic value].
Topics: Brain Injuries; Coma; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Probenecid; Ser | 1986 |