hydroxyindoleacetic acid has been researched along with Chronic Motor and Vocal Tic Disorder in 19 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Limited neurobiological data have implicated central arginine vasopressin in the pathobiology of obsessive-compulsive disorder (OCD)." | 7.69 | Elevated cerebrospinal fluid levels of oxytocin in obsessive-compulsive disorder. Comparison with Tourette's syndrome and healthy controls. ( Anderson, GM; Chappell, PB; Goodman, WK; Leckman, JF; McDougle, CJ; McSwiggan-Hardin, M; North, WG; Pauls, DL; Price, LH; Riddle, MA, 1994) |
| "Many studies have indicated that a variety of neurotransmitters are implicated in the pathophysiology of Tourette syndrome (TS), including dopamine (DA), serotonin (5-TH), homovanillic acid (HVA), and gamma-amino butyric acid (GABA)." | 5.16 | Effects of Chinese herbal medicine Ningdong granule on regulating dopamine (DA)/serotonin (5-TH) and gamma-amino butyric acid (GABA) in patients with Tourette syndrome. ( Li, A; Li, J; Qi, F; Wang, S; Zhao, L, 2012) |
| "Limited neurobiological data have implicated central arginine vasopressin in the pathobiology of obsessive-compulsive disorder (OCD)." | 3.69 | Elevated cerebrospinal fluid levels of oxytocin in obsessive-compulsive disorder. Comparison with Tourette's syndrome and healthy controls. ( Anderson, GM; Chappell, PB; Goodman, WK; Leckman, JF; McDougle, CJ; McSwiggan-Hardin, M; North, WG; Pauls, DL; Price, LH; Riddle, MA, 1994) |
| "Tourette syndrome patients with high levels of obsessive-compulsive symptoms were compared with patients without these symptoms on urinary measures of serotonin and its major metabolite, 5-hydroxyindoleacetic acid (5HIAA)." | 3.68 | Urinary indoleamines in Tourette syndrome patients with obsessive-compulsive characteristics. ( Baker, GB; Bornstein, RA, 1992) |
| "A prospective clinical and biochemical study on the effects of treatment with haloperidol has been performed in seven patients with Tourette syndrome." | 3.66 | Dopaminergic dsyfunction in Tourette syndrome. ( Butler, IJ; Coyle, JT; Seifert, WE; Singer, HS; Tune, LE, 1982) |
| "Tourette's syndrome is a chronic tic disorder in which motor and vocal tics begin in childhood, persist to adulthood, and occur predominantly in males, often in a familial setting." | 2.37 | Tourette's syndrome. Some new concepts. ( Butler, IJ, 1984) |
| "Homovanillic acid levels were 65 and 60 ng/ml, respectively, and 5-hydroxyindoleacetic acid levels were 36 and 39 ng/ml." | 1.28 | Gilles de la Tourette's syndrome in twins: clinical and neurochemical data. ( Goetz, CG; Tanner, CM, 1990) |
| "In five patients with Tourette's syndrome, we found in the CSF an elevated probenecid-induced accumulation of HVA, the major metabolite of dopamine." | 1.26 | Gilles de la Tourette's syndrome: biochemical approaches. ( Bowers, MB; Jutkowitz, R; Rosenbaum, D; Van Woert, MH, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (57.89) | 18.7374 |
| 1990's | 6 (31.58) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 1 (5.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, S | 1 |
| Qi, F | 1 |
| Li, J | 1 |
| Zhao, L | 1 |
| Li, A | 1 |
| Butler, IJ | 3 |
| van Woert, MH | 2 |
| Rosenbaum, D | 2 |
| Enna, SJ | 1 |
| Singer, HS | 2 |
| Tune, LE | 1 |
| Seifert, WE | 2 |
| Coyle, JT | 1 |
| Leckman, JF | 3 |
| Goodman, WK | 2 |
| North, WG | 1 |
| Chappell, PB | 1 |
| Price, LH | 1 |
| Pauls, DL | 1 |
| Anderson, GM | 3 |
| Riddle, MA | 3 |
| McSwiggan-Hardin, M | 1 |
| McDougle, CJ | 1 |
| de Groot, CM | 1 |
| Bornstein, RA | 3 |
| Baker, GB | 3 |
| Takano, K | 1 |
| Ishiguro, T | 1 |
| Oades, RD | 1 |
| Cohen, DJ | 3 |
| Shaywitz, BA | 1 |
| Caparulo, B | 1 |
| Young, JG | 1 |
| Bowers, MB | 2 |
| Koslow, SH | 1 |
| Caprioli, RM | 1 |
| Jutkowitz, R | 1 |
| Lal, S | 1 |
| Allen, J | 1 |
| Etienne, P | 1 |
| Sourkes, TL | 1 |
| Humphreys, P | 1 |
| Pollak, ES | 1 |
| Chatterjee, D | 1 |
| Goetz, CG | 1 |
| Tanner, CM | 1 |
| Rapoport, JL | 1 |
| Berrettini, WH | 1 |
| Hardin, M | 1 |
| Chappell, P | 1 |
| Bissette, G | 1 |
| Nemeroff, CB | 1 |
| Johannsson, B | 1 |
| Roos, BE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Double-Blind, Placebo-Controlled Trial Evaluating the Efficacy and Safety of Yi-Gan San in Children and Adolescents With Tourette's Disorder[NCT03564132] | Phase 2 | 38 participants (Actual) | Interventional | 2018-06-16 | Completed | ||
| [NCT00004325] | 200 participants | Observational | 1988-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for hydroxyindoleacetic acid and Chronic Motor and Vocal Tic Disorder
| Article | Year |
|---|---|
Tourette's syndrome. Some new concepts.
Topics: Antipsychotic Agents; Female; Haloperidol; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male | 1984 |
1 trial available for hydroxyindoleacetic acid and Chronic Motor and Vocal Tic Disorder
| Article | Year |
|---|---|
Effects of Chinese herbal medicine Ningdong granule on regulating dopamine (DA)/serotonin (5-TH) and gamma-amino butyric acid (GABA) in patients with Tourette syndrome.
Topics: Adolescent; Child; Dopamine; Drugs, Chinese Herbal; Enzyme-Linked Immunosorbent Assay; Female; gamma | 2012 |
17 other studies available for hydroxyindoleacetic acid and Chronic Motor and Vocal Tic Disorder
| Article | Year |
|---|---|
Overview of pharmacological approaches to therapy for Tourette syndrome.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Antipsychotic Agents; Child; Clonidine; Corpus Striatum; Fem | 1982 |
Dopaminergic dsyfunction in Tourette syndrome.
Topics: Adolescent; Dopamine; Female; Haloperidol; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male | 1982 |
Elevated cerebrospinal fluid levels of oxytocin in obsessive-compulsive disorder. Comparison with Tourette's syndrome and healthy controls.
Topics: Adolescent; Adult; Age of Onset; Arginine Vasopressin; Biogenic Amines; Comorbidity; Dynorphins; Fam | 1994 |
Obsessive-compulsive symptom clusters and urinary amine correlates in Tourette syndrome.
Topics: Adolescent; Biogenic Amines; Child; Dopamine; Factor Analysis, Statistical; Female; Humans; Hydroxyi | 1995 |
[A study of clinical pictures and monoamine metabolism of Gilles de la Tourette syndrome].
Topics: Adolescent; Adult; Biogenic Monoamines; Child; Echolalia; Haloperidol; Homovanillic Acid; Humans; Hy | 1993 |
Differential measures of 'sustained attention' in children with attention-deficit/hyperactivity or tic disorders: relations to monoamine metabolism.
Topics: Adolescent; Attention; Attention Deficit Disorder with Hyperactivity; Biogenic Monoamines; Case-Cont | 2000 |
Chronic, multiple tics of Gilles de la Tourette's disease. CSF acid monoamine metabolites after probenecid administration.
Topics: Adolescent; Brain; Child; Dextroamphetamine; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyind | 1978 |
Biogenic amine metabolism in Tourette syndrome.
Topics: Biogenic Amines; Child; Child, Preschool; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindole | 1979 |
Gilles de la Tourette's syndrome: biochemical approaches.
Topics: Haloperidol; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Tourette Syndrome | 1976 |
Dopaminergic function in Gilles de la Tourette's syndrome, Sydenham's chorea and torsion dystonia.
Topics: Adolescent; Adult; Apomorphine; Child; Chorea; Dopamine; Dystonia Musculorum Deformans; Female; Halo | 1976 |
Urinary indoleamines in Tourette syndrome patients with obsessive-compulsive characteristics.
Topics: Adolescent; Child; Female; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Indoles; Male; Obse | 1992 |
Brain monoamines and amino acids in Gilles de la Tourette's syndrome: a preliminary study of subcortical regions.
Topics: Adult; Aged; Amino Acids; Biogenic Monoamines; Brain Chemistry; Chromatography, High Pressure Liquid | 1992 |
Gilles de la Tourette's syndrome in twins: clinical and neurochemical data.
Topics: Child; Diseases in Twins; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Tourette Syndro | 1990 |
Childhood obsessive compulsive disorder.
Topics: Adolescent; Anorexia Nervosa; Behavior Therapy; Child; Child, Preschool; Clomipramine; Epilepsy, Tem | 1986 |
Neuropsychological correlates of urinary amine metabolites in Tourette's syndrome.
Topics: Adolescent; Adult; Child; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male | 1988 |
Elevated CSF dynorphin A [1-8] in Tourette's syndrome.
Topics: Dynorphins; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methoxyhydroxyphenylglycol; Peptide | 1988 |
5-Hydroxyindoleacetic acid and homovanillic acid in cerebrospinal fluid of patients with neurological diseases.
Topics: Adult; Brain Neoplasms; Central Nervous System Diseases; Cerebellar Ataxia; Cerebrovascular Disorder | 1974 |