hydroxyindoleacetic acid has been researched along with Choreoathetosis Self-Mutilation Hyperuricemia Syndrome in 11 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a patient with the Lesch-Nyhan syndrome we found decreased spinal fluid 5-hydroxyindole acetic acid (5-HIAA), the major metabolite of serotonin, and decreased homovanillic acid (HVA), the major metabolite of dopamine, indicating a decrease in monoamine metabolism." | 7.66 | Effects of L-5-hydroxytryptophan on monoamine and amino acids turnover in the Lesch-Nyhan syndrome. ( Castells, S; Chakrabarti, C; Hurwic, M; Nyhan, WL; Perel, JM; Winsberg, BG, 1979) |
| "The effects of 5-hydroxytryptophan (5-HTP), a serotonin precursor, were studied in a boy with the Lesch-Nyhan syndrome." | 7.65 | The use of 5-hydroxytryptophan in a child with Lesch-Nyhan syndrome. ( Anders, TF; Barchas, JD; Berger, PA; Cann, HM; Ciaranello, RD, 1976) |
| "Serial determinations of spinal fluid homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA) were made in four patients with the Lesch-Nyhan syndrome over a 5-year period." | 3.67 | Lesch-Nyhan syndrome: CSF neurotransmitter abnormalities. ( Edwards, NL; Hutchinson, RJ; Johnston, MV; Silverstein, FS, 1985) |
| "In a patient with the Lesch-Nyhan syndrome we found decreased spinal fluid 5-hydroxyindole acetic acid (5-HIAA), the major metabolite of serotonin, and decreased homovanillic acid (HVA), the major metabolite of dopamine, indicating a decrease in monoamine metabolism." | 3.66 | Effects of L-5-hydroxytryptophan on monoamine and amino acids turnover in the Lesch-Nyhan syndrome. ( Castells, S; Chakrabarti, C; Hurwic, M; Nyhan, WL; Perel, JM; Winsberg, BG, 1979) |
| "The effects of 5-hydroxytryptophan (5-HTP), a serotonin precursor, were studied in a boy with the Lesch-Nyhan syndrome." | 3.65 | The use of 5-hydroxytryptophan in a child with Lesch-Nyhan syndrome. ( Anders, TF; Barchas, JD; Berger, PA; Cann, HM; Ciaranello, RD, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (72.73) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bavaresco, CS | 1 |
| Chiarani, F | 1 |
| Duringon, E | 1 |
| Ferro, MM | 1 |
| Cunha, CD | 1 |
| Netto, CA | 1 |
| Wyse, AT | 1 |
| Jinnah, HA | 1 |
| Wojcik, BE | 1 |
| Hunt, M | 1 |
| Narang, N | 1 |
| Lee, KY | 1 |
| Goldstein, M | 1 |
| Wamsley, JK | 1 |
| Langlais, PJ | 1 |
| Friedmann, T | 1 |
| Nyhan, WL | 3 |
| Sweetman, L | 1 |
| Borden, M | 1 |
| Kulovich, S | 1 |
| Kaufman, I | 1 |
| Castells, S | 1 |
| Chakrabarti, C | 1 |
| Winsberg, BG | 1 |
| Hurwic, M | 1 |
| Perel, JM | 1 |
| Ciaranello, RD | 1 |
| Anders, TF | 1 |
| Barchas, JD | 1 |
| Berger, PA | 1 |
| Cann, HM | 1 |
| Edwards, NL | 2 |
| Silverstein, FS | 2 |
| Johnston, MV | 2 |
| Van Praag, HM | 1 |
| Plutchik, R | 1 |
| Conte, H | 1 |
| Jankovic, J | 1 |
| Caskey, TC | 1 |
| Stout, JT | 1 |
| Butler, IJ | 1 |
| Hutchinson, RJ | 1 |
| Mizuno, TI | 1 |
| Yugari, Y | 1 |
1 review available for hydroxyindoleacetic acid and Choreoathetosis Self-Mutilation Hyperuricemia Syndrome
| Article | Year |
|---|---|
Dopamine function in Lesch-Nyhan disease.
Topics: Dopamine; Humans; Hydroxyindoleacetic Acid; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Synd | 2000 |
1 trial available for hydroxyindoleacetic acid and Choreoathetosis Self-Mutilation Hyperuricemia Syndrome
| Article | Year |
|---|---|
Letter: Self mutilation in Lesch-Nyhan syndrome.
Topics: 5-Hydroxytryptophan; Administration, Oral; Child; Dihydroxyphenylalanine; Humans; Hydroxyindoleaceti | 1974 |
9 other studies available for hydroxyindoleacetic acid and Choreoathetosis Self-Mutilation Hyperuricemia Syndrome
| Article | Year |
|---|---|
Intrastriatal injection of hypoxanthine reduces striatal serotonin content and impairs spatial memory performance in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxyindole | 2007 |
Dopamine deficiency in a genetic mouse model of Lesch-Nyhan disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Caudate Nucleus; Disease Models, Animal; Dopa | 1994 |
Altered excreton of 5-hydroxyindoleacetic acid and glycine in patients with the Lesch-Nyhan disease.
Topics: 5-Hydroxytryptophan; Adolescent; Carbidopa; Child; Child, Preschool; Glycine; Humans; Hydroxyindolea | 1977 |
Effects of L-5-hydroxytryptophan on monoamine and amino acids turnover in the Lesch-Nyhan syndrome.
Topics: 5-Hydroxytryptophan; Amino Acids; Carbidopa; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleaceti | 1979 |
The use of 5-hydroxytryptophan in a child with Lesch-Nyhan syndrome.
Topics: 5-Hydroxytryptophan; Child, Preschool; Cold Temperature; Crying; Dopamine beta-Hydroxylase; Dose-Res | 1976 |
Purine and monoamine metabolites in cerebrospinal fluid.
Topics: Age Factors; Child; Child, Preschool; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; I | 1986 |
The serotonin hypothesis of (auto)aggression. Critical appraisal of the evidence.
Topics: Aggression; Brain; Depressive Disorder; Hostility; Humans; Hydroxyindoleacetic Acid; Lesch-Nyhan Syn | 1986 |
Lesch-Nyhan syndrome: a study of motor behavior and cerebrospinal fluid neurotransmitters.
Topics: Carbidopa; Catecholamines; Child; Child, Preschool; Fluphenazine; Glycols; Homovanillic Acid; Humans | 1988 |
Lesch-Nyhan syndrome: CSF neurotransmitter abnormalities.
Topics: Adolescent; Child; Child, Preschool; Chromatography, High Pressure Liquid; Dopamine; Homovanillic Ac | 1985 |