Page last updated: 2024-10-21

hydroxyindoleacetic acid and Child Behavior Disorders

hydroxyindoleacetic acid has been researched along with Child Behavior Disorders in 12 studies

(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.

Child Behavior Disorders: Disturbances considered to be pathological based on age and stage appropriateness, e.g., conduct disturbances and anaclitic depression. This concept does not include psychoneuroses, psychoses, or personality disorders with fixed patterns.

Research Excerpts

ExcerptRelevanceReference
" The 5-hydroxyindoleacetic acid concentration significantly predicted severity of physical aggression during follow-up."3.68A 2-year prospective follow-up study of children and adolescents with disruptive behavior disorders. Prediction by cerebrospinal fluid 5-hydroxyindoleacetic acid, homovanillic acid, and autonomic measures? ( Bartko, JJ; Hamburger, SD; Hibbs, ED; Keysor, CS; Kruesi, MJ; Rapoport, JL; Zahn, TP, 1992)
"Cerebrospinal fluid levels of 5-hydroxyindoleacetic acid, a metabolite of serotonin, were measured in relation to aggression, impulsivity, and social functioning in 29 children and adolescents with disruptive behavior disorders."3.68Cerebrospinal fluid monoamine metabolites, aggression, and impulsivity in disruptive behavior disorders of children and adolescents. ( Brown, GL; Hamburger, S; Hibbs, E; Kruesi, MJ; Lenane, M; Potter, WZ; Rapoport, JL, 1990)
"Homovanillic acid (HVA) levels were significantly lower in CD youth under age 12."1.29Biodevelopmental aspects of conduct disorder in boys. ( Bjorn, J; Bowden, CL; Gabel, S; Shindledecker, R; Stadler, J, 1993)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19907 (58.33)18.7374
1990's4 (33.33)18.2507
2000's1 (8.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Madej, A1
Pakszys, W1
Young, JG1
Cohen, DJ1
Shaywitz, SE1
Caparulo, BK1
Kavanagh, ME1
Hunt, RD1
Leckman, JF1
Anderson, GM1
Detlor, J1
Harcherik, D1
Shaywitz, BA1
Gabel, S1
Stadler, J1
Bjorn, J1
Shindledecker, R1
Bowden, CL1
Mitsis, EM1
Halperin, JM1
Newcorn, JH1
Kruesi, MJ7
Hibbs, ED1
Zahn, TP1
Keysor, CS1
Hamburger, SD3
Bartko, JJ1
Rapoport, JL5
Hamburger, S1
Hibbs, E1
Potter, WZ3
Lenane, M1
Brown, GL2
Swedo, S1
Leonard, H1
Rubinow, DR1
Linnoila, M1
Petersen, R1
Hyman, SL1
Porter, CA1
Page, TJ1
Iwata, BA1
Kissel, R1
Batshaw, ML1
Swedo, SE2
Leonard, HL1
Cheslow, DL1
Stipetic, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00004325]200 participants Observational1988-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for hydroxyindoleacetic acid and Child Behavior Disorders

ArticleYear
Serotonin and aggression in children.
    Current psychiatry reports, 2000, Volume: 2, Issue:2

    Topics: Adolescent; Aggression; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorde

2000

Other Studies

11 other studies available for hydroxyindoleacetic acid and Child Behavior Disorders

ArticleYear
Psychic and motor functions and serotonin (5 HT) metabolism in brain-damaged children before and after administration of Niamid and Raupasil.
    Polish medical journal, 1967, Volume: 6, Issue:5

    Topics: Adolescent; Brain Damage, Chronic; Child; Child Behavior Disorders; Female; Humans; Hydroxyindoleace

1967
Assessment of brain function in clinical pediatric research: behavioral and biological strategies.
    Schizophrenia bulletin, 1982, Volume: 8, Issue:2

    Topics: Catecholamines; Child; Child Behavior Disorders; Developmental Disabilities; Ethics, Medical; Homova

1982
Biodevelopmental aspects of conduct disorder in boys.
    Child psychiatry and human development, 1993,Winter, Volume: 24, Issue:2

    Topics: Age Factors; Child; Child Behavior Disorders; Dopamine beta-Hydroxylase; Homovanillic Acid; Humans;

1993
A 2-year prospective follow-up study of children and adolescents with disruptive behavior disorders. Prediction by cerebrospinal fluid 5-hydroxyindoleacetic acid, homovanillic acid, and autonomic measures?
    Archives of general psychiatry, 1992, Volume: 49, Issue:6

    Topics: Adolescent; Aggression; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorde

1992
Cerebrospinal fluid monoamine metabolites, aggression, and impulsivity in disruptive behavior disorders of children and adolescents.
    Archives of general psychiatry, 1990, Volume: 47, Issue:5

    Topics: Adolescent; Age Factors; Aggression; Attention Deficit Disorder with Hyperactivity; Child; Child Beh

1990
CSF somatostatin in childhood psychiatric disorders: a preliminary investigation.
    Psychiatry research, 1990, Volume: 33, Issue:3

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorders; Depressi

1990
Carbohydrate craving, conduct disorder, and low 5HIAA.
    Psychiatry research, 1985, Volume: 16, Issue:1

    Topics: Child; Child Behavior Disorders; Dietary Carbohydrates; Female; Humans; Hydroxyindoleacetic Acid

1985
Behavior management of feeding disturbances in urea cycle and organic acid disorders.
    The Journal of pediatrics, 1987, Volume: 111, Issue:4

    Topics: Adult; Amino Acid Metabolism, Inborn Errors; Anorexia; Argininosuccinic Acid; Behavior Therapy; Chil

1987
Concentration gradient of CSF monoamine metabolites in children and adolescents.
    Biological psychiatry, 1988, Volume: 24, Issue:5

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorders; Child De

1988
Cruelty to animals and CSF 5HIAA.
    Psychiatry research, 1989, Volume: 28, Issue:1

    Topics: Aggression; Animal Welfare; Child; Child Behavior Disorders; Female; Follow-Up Studies; Humans; Hydr

1989
Lack of seasonal variation in pediatric lumbar cerebrospinal fluid neurotransmitter metabolite concentrations.
    Acta psychiatrica Scandinavica, 1989, Volume: 80, Issue:6

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorders; Female;

1989