Page last updated: 2024-10-21

hydroxyindoleacetic acid and Cerebrovascular Disorders

hydroxyindoleacetic acid has been researched along with Cerebrovascular Disorders in 17 studies

(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.

Cerebrovascular Disorders: A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.

Research Excerpts

ExcerptRelevanceReference
"For understanding of the role of monoamines in cerebral ischemia, 3-methoxy-4-hydroxyphenylglycol (MHPG), hydroxyindoleacetic acid (5HIAA) homovanillic acid (HVA) the three major monoamine metabolites in CSF of 33 patients and 18 controls were measured with high-performance liquid chromatography."3.68[The changes of monoamine metabolites in CSF of patients with cerebral stroke]. ( Tang, HZ, 1991)
"The concentrations of homovanillic acid (HVA), 3-methoxy, 4-hydroxyphenylglycol (MHPG), and 5-hydroxyindolylacetic acid (5-HIAA) were measured in samples of ventricular cerebrospinal fluid (CSF) taken from 15 patients who were comatose as a result of an acute head injury, a tumour, or a cerebrovascular accident."3.66Amine metabolites in ventricular cerebrospinal fluid in coma. ( Tsementzis, SA; Wilson, H; Yates, CM, 1979)
"It is proposed that the migraine attack is explicable by an interaction between the brain and the cranial circulation in subjects with unstable vascular and pain-control mechanisms."2.38The pathophysiology of migraine: a tentative synthesis. ( Lance, JW, 1992)
"Patients with hypoxic encephalopathy consisted of 5 with apallic syndrome and one patient with Lance-Adams syndrome."1.28[Study on the concentration of 5-hydroxyindoleacetic acid (5-HIAA) in the lumbar cerebrospinal fluid (CSF) in neurological diseases]. ( Fukuda, H; Hara, K; Kameyama, M; Nakamura, S; Udaka, F, 1989)
"Our results indicate that during cerebral ischemia a large increase in extracellular dopamine concentration in the caudate nucleus occurs, probably as a result of energy failure of the cell membranes."1.27Striatal dopamine in acute cerebral ischemia of stroke-resistant rats. ( Kawano, T; Miyake, H; Mori, K; Tsutsumi, K, 1988)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199013 (76.47)18.7374
1990's3 (17.65)18.2507
2000's0 (0.00)29.6817
2010's1 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Herbert, MK1
Kuiperij, H1
Bloem, BR1
Verbeek, MM1
Misra, SS1
Singh, KS1
Bhargava, KP1
Jellinger, K1
Riederer, P1
Togashi, H1
Matsumoto, M1
Yoshioka, M1
Hirokami, M1
Minami, M1
Saito, H1
Mrsulja, BB1
Mrsulja, BJ1
Spatz, M1
Klatzo, I1
Yates, CM1
Tsementzis, SA1
Wilson, H1
Lance, JW1
Tang, HZ1
Kawakami, M1
Itoh, T1
Minegishi, A1
Ishizaki, T1
Yoshida, Y1
Ahagon, A1
Shibata, N1
Kobayashi, H1
Lamers, KJ1
Schoonderwaldt, HC1
Borkent, MV1
Theeuwes, AG1
Doesburg, WH1
Wevers, RA1
Kawano, T1
Tsutsumi, K1
Miyake, H1
Mori, K1
Fukuda, H1
Nakamura, S1
Hara, K1
Udaka, F1
Kameyama, M1
Himwich, WA1
Fukuyama, GS1
Johannsson, B1
Roos, BE1
Welch, KM1
Meyer, JS1
Kwant, S1
Kawiak, W1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Pilot Study of F-18 Paclitaxel (FPAC) PET for Evaluating Drug Delivery of Solid Tumors in Breast, Lung, Renal, and Adrenal Cancers[NCT01086696]Early Phase 16 participants (Actual)Interventional2010-03-09Terminated
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for hydroxyindoleacetic acid and Cerebrovascular Disorders

ArticleYear
The pathophysiology of migraine: a tentative synthesis.
    Pathologie-biologie, 1992, Volume: 40, Issue:4

    Topics: Brain Stem; Calcitonin Gene-Related Peptide; Cerebrovascular Circulation; Cerebrovascular Disorders;

1992

Other Studies

16 other studies available for hydroxyindoleacetic acid and Cerebrovascular Disorders

ArticleYear
Levels of HVA, 5-HIAA, and MHPG in the CSF of vascular parkinsonism compared to Parkinson's disease and controls.
    Journal of neurology, 2013, Volume: 260, Issue:12

    Topics: Aged; Cerebrovascular Disorders; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male;

2013
Estimation of 5-hydroxytryptamine (5-HT) level in cerebrospinal fluid of patients with intracranial or spinal lesions.
    Journal of neurology, neurosurgery, and psychiatry, 1967, Volume: 30, Issue:2

    Topics: Cerebrovascular Disorders; Chromatography, Paper; Humans; Hydroxyindoleacetic Acid; Paraplegia; Quad

1967
[Central neurotransmitters in cerebral ischemia and stroke].
    Fortschritte der Neurologie-Psychiatrie, 1983, Volume: 51, Issue:3

    Topics: Animals; Blood-Brain Barrier; Brain Edema; Brain Ischemia; Cerebral Infarction; Cerebrovascular Diso

1983
Neurochemical profiles in cerebrospinal fluid of stroke-prone spontaneously hypertensive rats.
    Neuroscience letters, 1994, Jan-17, Volume: 166, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Animals; Biogenic Monoamines; Blood Pressure; Cerebro

1994
Brain serotonin after experimental vascular occlusion.
    Neurology, 1976, Volume: 26, Issue:8

    Topics: Animals; Cerebral Cortex; Cerebrovascular Disorders; Fenclonine; Gerbillinae; Hydroxyindoleacetic Ac

1976
Amine metabolites in ventricular cerebrospinal fluid in coma.
    Journal of neurology, neurosurgery, and psychiatry, 1979, Volume: 42, Issue:10

    Topics: Adolescent; Adult; Brain Injuries; Brain Neoplasms; Cerebrospinal Fluid Proteins; Cerebrovascular Di

1979
[The changes of monoamine metabolites in CSF of patients with cerebral stroke].
    Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 1991, Volume: 24, Issue:3

    Topics: Brain Ischemia; Cerebrovascular Disorders; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Ac

1991
[Effects of idebenone on monoamine metabolites in the cerebrospinal fluid of patients with cerebrovascular dementia].
    No to shinkei = Brain and nerve, 1986, Volume: 38, Issue:2

    Topics: Aged; Benzoquinones; Biogenic Amines; Cerebrovascular Disorders; Chromatography, High Pressure Liqui

1986
Plasma monoaminergic metabolites and catecholamines in subarachnoid hemorrhage. Clinical implications.
    Archives of neurology, 1987, Volume: 44, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Catecholamines; Cerebrovascular Disorders; Dopamine; Ep

1987
The effects of acute cerebrovascular disease on serum and cerebrospinal fluid parameters.
    Clinical neurology and neurosurgery, 1987, Volume: 89, Issue:1

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Aspartate Aminotransferases; Cerebrospinal Fluid Prot

1987
Striatal dopamine in acute cerebral ischemia of stroke-resistant rats.
    Stroke, 1988, Volume: 19, Issue:12

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Ischemia; Caudate Nucleus; Cerebrovascular Disorders;

1988
[Study on the concentration of 5-hydroxyindoleacetic acid (5-HIAA) in the lumbar cerebrospinal fluid (CSF) in neurological diseases].
    Rinsho shinkeigaku = Clinical neurology, 1989, Volume: 29, Issue:9

    Topics: Adult; Aged; Alzheimer Disease; Brain Diseases; Cerebrovascular Disorders; Female; Humans; Hydroxyin

1989
Genral neurophysiology (biochemical aspects).
    Progress in neurology and psychiatry, 1971, Volume: 26

    Topics: Age Factors; Animals; Bipolar Disorder; Blood-Brain Barrier; Brain; Brain Diseases; Cerebrovascular

1971
5-Hydroxyindoleacetic acid and homovanillic acid in cerebrospinal fluid of patients with neurological diseases.
    European neurology, 1974, Volume: 11, Issue:1

    Topics: Adult; Brain Neoplasms; Central Nervous System Diseases; Cerebellar Ataxia; Cerebrovascular Disorder

1974
Estimation of levels of serotonin and 5-hydroxyindoles in whole blood by an autoanalytical procedure: observations on the blood-brain barrier.
    Journal of neurochemistry, 1972, Volume: 19, Issue:4

    Topics: 5-Hydroxytryptophan; Aldehydes; Animals; Autoanalysis; Blood-Brain Barrier; Cerebrovascular Disorder

1972
Investigations on urinary excretion of 5-hydroxyindoleacetic acid (5-HIAA) in patients after cerebral stroke.
    Polish medical journal, 1968, Volume: 7, Issue:4

    Topics: Brain Diseases; Cerebral Hemorrhage; Cerebrovascular Disorders; Humans; Hydroxyindoleacetic Acid

1968