hydroxyindoleacetic acid has been researched along with Cerebral Ischemia in 24 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of citalopram, a serotonin (5-HT) reuptake inhibitor, on cerebral blood flow (CBF) and concentration of 5-HT and its metabolite were investigated in spontaneously hypertensives rats (SHR) subjected to forebrain ischemia." | 7.69 | Citalopram, a serotonin reuptake inhibitor, and brain ischemia in SHR. ( Fujishima, M; Ibayashi, S; Izumi, J; Nagao, T; Sadoshima, S, 1995) |
| "In rats with cerebral ischemia, a low dose (10 mg/kg, i." | 5.27 | Effects of idebenone (CV-2619) on metabolism of monoamines, especially serotonin, in the brain of normal rats and rats with cerebral ischemia. ( Kakihana, M; Nagai, Y; Nagaoka, A; Nagawa, Y; Narumi, S; Yamazaki, N, 1985) |
| "The effects of citalopram, a serotonin (5-HT) reuptake inhibitor, on cerebral blood flow (CBF) and concentration of 5-HT and its metabolite were investigated in spontaneously hypertensives rats (SHR) subjected to forebrain ischemia." | 3.69 | Citalopram, a serotonin reuptake inhibitor, and brain ischemia in SHR. ( Fujishima, M; Ibayashi, S; Izumi, J; Nagao, T; Sadoshima, S, 1995) |
| "For understanding of the role of monoamines in cerebral ischemia, 3-methoxy-4-hydroxyphenylglycol (MHPG), hydroxyindoleacetic acid (5HIAA) homovanillic acid (HVA) the three major monoamine metabolites in CSF of 33 patients and 18 controls were measured with high-performance liquid chromatography." | 3.68 | [The changes of monoamine metabolites in CSF of patients with cerebral stroke]. ( Tang, HZ, 1991) |
| "Rat striatal extracellular fluid levels of dopamine, serotonin, 3-methoxytyramine (3-MT), 3,4-dihydroxyphenylacetic acid (DOPAC), homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA) were measured before, during and after transient, global cerebral ischemia in awake rats using in vivo brain microdialysis." | 3.67 | Effects of transient, global, cerebral ischemia on striatal extracellular dopamine, serotonin and their metabolites. ( Clemens, JA; Phebus, LA, 1989) |
| "To clarify the rule of monoamine in cerebral ischemia, 3-methoxy-4-hydroxyphenylglycol (MHPG), 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) in cerebrospinal fluid (CSF) of 33 patients and 18 controls were measured with high performance liquid chromatography." | 3.67 | Monoamine metabolites in cerebrospinal fluid during acute cerebral ischemia. ( Huang, YQ; Lu, XF; Ou, YS; Tang, HZ; Wang, KJ, 1989) |
| "Vannucci, Experimental biology of cerebral hypoxia-ischemia: relation to perinatal brain damage, Pediatr." | 1.30 | Anoxic and hypoxic immature rat model for measurement of monoamine using in vivo microdialysis. ( Ishida, A; Nakajima, W; Takada, G, 1999) |
| "In rats with cerebral ischemia, idebenone (10 mg/kg, i." | 1.28 | Effects of idebenone on metabolism of monoamines and cyclic AMP formation in rats. ( Kakihana, M; Nagai, Y; Nagaoka, A; Nagawa, Y; Narumi, S; Yamazaki, N, 1989) |
| "Our results indicate that during cerebral ischemia a large increase in extracellular dopamine concentration in the caudate nucleus occurs, probably as a result of energy failure of the cell membranes." | 1.27 | Striatal dopamine in acute cerebral ischemia of stroke-resistant rats. ( Kawano, T; Miyake, H; Mori, K; Tsutsumi, K, 1988) |
| "In rats with cerebral ischemia, a low dose (10 mg/kg, i." | 1.27 | Effects of idebenone (CV-2619) on metabolism of monoamines, especially serotonin, in the brain of normal rats and rats with cerebral ischemia. ( Kakihana, M; Nagai, Y; Nagaoka, A; Nagawa, Y; Narumi, S; Yamazaki, N, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (54.17) | 18.7374 |
| 1990's | 10 (41.67) | 18.2507 |
| 2000's | 1 (4.17) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mitsuyo, T | 1 |
| Adachi, N | 1 |
| Yorozuya, T | 1 |
| Tabo, E | 1 |
| Nagaro, T | 1 |
| Arai, T | 1 |
| Pau, A | 1 |
| Sehrobundt Viale, E | 1 |
| Turtas, S | 1 |
| Jellinger, K | 1 |
| Riederer, P | 1 |
| Stelmasiak, Z | 1 |
| Kogure, K | 1 |
| Nagao, T | 1 |
| Ibayashi, S | 1 |
| Sadoshima, S | 1 |
| Izumi, J | 1 |
| Fujishima, M | 1 |
| Takagi, N | 1 |
| Miyake, K | 1 |
| Ohiwa, A | 1 |
| Nukaga, R | 1 |
| Takeo, S | 1 |
| Thaminy, S | 1 |
| Bellissant, E | 1 |
| Maginn, M | 1 |
| Decombe, R | 1 |
| Allain, H | 1 |
| Bentué-Ferrer, D | 1 |
| Nakajima, W | 1 |
| Ishida, A | 1 |
| Takada, G | 1 |
| Globus, MY | 1 |
| Wester, P | 1 |
| Busto, R | 1 |
| Dietrich, WD | 1 |
| Luthman, J | 1 |
| Lindqvist, E | 1 |
| Dell'Anna, E | 1 |
| Kojima, H | 1 |
| Shiotani, T | 1 |
| Tachizawa, H | 1 |
| Olson, L | 1 |
| Haba, K | 1 |
| Ogawa, N | 1 |
| Asanuma, M | 1 |
| Hirata, H | 1 |
| Mori, A | 1 |
| Heyes, MP | 1 |
| Nowak, TS | 1 |
| Tang, HZ | 2 |
| Bao, WL | 1 |
| Sun, FY | 1 |
| Tong, JF | 1 |
| Zhang, LM | 1 |
| Zhang, AZ | 1 |
| Ferrarese, C | 1 |
| Bassi, S | 1 |
| Frattola, L | 1 |
| Locatelli, P | 1 |
| Piolti, R | 1 |
| Trabucchi, M | 1 |
| Weinberger, J | 1 |
| Nieves-Rosa, J | 1 |
| Ogura, K | 1 |
| Shibuya, M | 1 |
| Kanamori, M | 1 |
| Suzuki, Y | 1 |
| Harada, T | 1 |
| Okada, T | 1 |
| Tanoi, C | 1 |
| Kageyama, N | 1 |
| Kawano, T | 2 |
| Miyake, H | 2 |
| Tsutsumi, K | 2 |
| Mori, K | 2 |
| Phebus, LA | 1 |
| Clemens, JA | 1 |
| Nagai, Y | 2 |
| Narumi, S | 2 |
| Kakihana, M | 2 |
| Yamazaki, N | 2 |
| Nagaoka, A | 2 |
| Nagawa, Y | 2 |
| Lu, XF | 1 |
| Wang, KJ | 1 |
| Ou, YS | 1 |
| Huang, YQ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Study of F-18 Paclitaxel (FPAC) PET for Evaluating Drug Delivery of Solid Tumors in Breast, Lung, Renal, and Adrenal Cancers[NCT01086696] | Early Phase 1 | 6 participants (Actual) | Interventional | 2010-03-09 | Terminated | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
24 other studies available for hydroxyindoleacetic acid and Cerebral Ischemia
| Article | Year |
|---|---|
Facilitation of ischemia-induced release of dopamine and neuronal damage by dexamethasone in the rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenal Cortex Hormones; Animals; Biogenic Monoamines; Blood Pressur | 2003 |
Effect of omental transposition on to the brain on the cortical content of norepinephrine, dopamine, 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in experimental cerebral ischaemia.
Topics: Animals; Biogenic Amines; Brain; Brain Ischemia; Cerebral Cortex; Dopamine; Hydroxyindoleacetic Acid | 1982 |
[Central neurotransmitters in cerebral ischemia and stroke].
Topics: Animals; Blood-Brain Barrier; Brain Edema; Brain Ischemia; Cerebral Infarction; Cerebrovascular Diso | 1983 |
Effect of ischemia on monoamine metabolism. Brain monoamine metabolites in cerebrospinal fluid of patients with recent cerebral infarction.
Topics: Aged; Brain Ischemia; Cerebral Infarction; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Ac | 1982 |
[Cerebral ischemia and changes in the brain monoamines].
Topics: Animals; Biogenic Amines; Brain; Brain Ischemia; Cyclic AMP; Dopamine; Epinephrine; Hydroxyindoleace | 1983 |
Citalopram, a serotonin reuptake inhibitor, and brain ischemia in SHR.
Topics: Animals; Blood Pressure; Body Temperature; Brain Chemistry; Brain Ischemia; Cerebrovascular Circulat | 1995 |
Effects of delayed treatment with nafronyl oxalate on microsphere embolism-induced changes in monoamine levels of rat brain regions.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Brain; Brain Ischemia; Dopamine; Hydro | 1996 |
Effect of brain microdialysis on aminergic transmitter levels in repeated cerebral global transient ischemia in rat.
Topics: Amphetamines; Animals; Blood Glucose; Brain Chemistry; Brain Ischemia; Carotid Arteries; Cerebrovasc | 1996 |
Anoxic and hypoxic immature rat model for measurement of monoamine using in vivo microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Brain; Brain Chemistry; Brain Ischemia; C | 1999 |
Ischemia-induced extracellular release of serotonin plays a role in CA1 neuronal cell death in rats.
Topics: Animals; Brain Ischemia; Cell Survival; Corpus Striatum; Dialysis; Extracellular Space; Hippocampus; | 1992 |
Effects of DM-9384, a pyrrolidone derivative, on ischemia-induced changes in the central monoamine systems.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Brain Chemistry; Brain Ischemia; Centr | 1992 |
Comparison of the effects of bifemelane hydrochloride, idebenone and indeloxazine hydrochloride on ischemia-induced changes in brain monoamines and their metabolites in gerbils.
Topics: Animals; Benzhydryl Compounds; Benzoquinones; Biogenic Monoamines; Brain Chemistry; Brain Ischemia; | 1992 |
Delayed increases in regional brain quinolinic acid follow transient ischemia in the gerbil.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Dopamin | 1990 |
[The changes of monoamine metabolites in CSF of patients with cerebral stroke].
Topics: Brain Ischemia; Cerebrovascular Disorders; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Ac | 1991 |
[Antagonistic effect of phencyclidine on cerebral ischemic damage of rats].
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Ischemia; Catecholamines; Cerebral Cortex; Dop | 1991 |
Different patterns of CSF neurotransmitter metabolism in patients with left or right hemispheric stroke.
Topics: Aged; Biogenic Amines; Brain Ischemia; Female; Functional Laterality; Homovanillic Acid; Humans; Hyd | 1986 |
Metabolism of monoamine neurotransmitters in the evolution of infarction in ischemic striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Brain Ischemia; Carotid Arteries; Cerebral | 1987 |
[Measurements of monoamine neurotransmitter metabolism by in vivo voltammetry].
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Brain; Brain Ischemia; Dopamine; Electrodi | 1987 |
[Sequential changes in dopamine and monoamine metabolites in ischemic rat caudate nucleus. In vivo dialysis coupled with high-performance liquid chromatography with electrochemical detection].
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Brain Ischemia; Caudate Nucleus; Chromatog | 1988 |
Striatal dopamine in acute cerebral ischemia of stroke-resistant rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Ischemia; Caudate Nucleus; Cerebrovascular Disorders; | 1988 |
Effects of transient, global, cerebral ischemia on striatal extracellular dopamine, serotonin and their metabolites.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Ischemia; Corpus Striatum; Dopamine; Extracellular Sp | 1989 |
Effects of idebenone on metabolism of monoamines and cyclic AMP formation in rats.
Topics: Animals; Benzoquinones; Biogenic Monoamines; Brain; Brain Ischemia; Cyclic AMP; Disease Models, Anim | 1989 |
Monoamine metabolites in cerebrospinal fluid during acute cerebral ischemia.
Topics: Aged; Biogenic Monoamines; Brain Ischemia; Electronic Data Processing; Female; Homovanillic Acid; Hu | 1989 |
Effects of idebenone (CV-2619) on metabolism of monoamines, especially serotonin, in the brain of normal rats and rats with cerebral ischemia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzoquinones; Biogenic Amines; Brain; Brain Ischemia; Chro | 1985 |