hydroxyindoleacetic acid has been researched along with Carcinoid Heart Disease in 36 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
Carcinoid Heart Disease: Cardiac manifestation of gastrointestinal CARCINOID TUMOR that metastasizes to the liver. Substances secreted by the tumor cells, including SEROTONIN, promote fibrous plaque formation in ENDOCARDIUM and its underlying layers. These deposits cause distortion of the TRICUSPID VALVE and the PULMONARY VALVE eventually leading to STENOSIS and valve regurgitation.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The presence of carcinoid heart disease and high urinary output of 5-hydroxyindoleacetic acid preoperatively were statistically significant risk factors for perioperative complications." | 3.71 | Perianaesthetic risks and outcomes of abdominal surgery for metastatic carcinoid tumours. ( Kinney, MA; Maxson, PM; Nagorney, DM; Rubin, J; Schroeder, DR; Warner, MA; Warner, ME, 2001) |
| "To correlate clinical and laboratory variables in carcinoid heart disease, clinical data, echocardiograms, 24-hour urinary 5-hydroxyindoleacetic acid levels and liver function tests were evaluated in 30 patients with the carcinoid syndrome." | 3.67 | Clinical and echocardiographic comparison of patients with the carcinoid syndrome with and without carcinoid heart disease. ( Himelman, RB; Schiller, NB, 1989) |
| "The prognosis and treatment of carcinoids vary based on location and histology, and therapy must be tailored to each patient." | 2.43 | Carcinoid tumors. ( Chen, H; Sippel, RS, 2006) |
| "Hydroxyindoleacetic acid (5-HIAA) was identified to predict the occurrence of CHD (OR, 1." | 1.91 | Prevalence, one-year-incidence and predictors of carcinoid heart disease. ( Brand, A; Dreger, H; Franke, MR; Knebel, F; Mattig, I; Pschowski, R; Stangl, K, 2023) |
| "Primary ovarian carcinoid tumors are rare neuroendocrine tumors, and can be associated with carcinoid syndrome and carcinoid heart disease." | 1.72 | A Case of Primary Insular Ovarian Carcinoid Tumor with Hyperandrogenism and Carcinoid Heart Disease. ( Al-Agha, R; Anaka, MR; Mansour, S, 2022) |
| "Carcinoid heart disease is a rare disease, and its prevalence is uncertain." | 1.36 | Echocardiographic follow-up of treated patients with carcinoid syndrome. ( Bachet, JB; Dubourg, O; Mansencal, N; Mitry, E; Rougier, P, 2010) |
| "Small pericardial effusions were present in 10 patients (14%)." | 1.29 | Carcinoid heart disease. Clinical and echocardiographic spectrum in 74 patients. ( Callahan, JA; Khandheria, BK; Kvols, LK; Pellikka, PA; Pitot, HC; Seward, JB; Tajik, AJ, 1993) |
| "The patient had symptoms of the carcinoid syndrome and at autopsy was found to have evidence of carcinoid heart disease." | 1.25 | Oat cell carcinoma of the bronchus and the carcinoid syndrome. ( Eggleston, JC; Salyer, DC, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (25.00) | 18.7374 |
| 1990's | 2 (5.56) | 18.2507 |
| 2000's | 11 (30.56) | 29.6817 |
| 2010's | 9 (25.00) | 24.3611 |
| 2020's | 5 (13.89) | 2.80 |
| Authors | Studies |
|---|---|
| Kostiainen, I | 1 |
| Karppinen, N | 1 |
| Simonen, P | 1 |
| Rosengård-Bärlund, M | 1 |
| Lindén, R | 1 |
| Tarkkanen, M | 1 |
| Gordin, D | 1 |
| Rapola, J | 1 |
| Schalin-Jäntti, C | 1 |
| Matikainen, N | 1 |
| Mansour, S | 1 |
| Anaka, MR | 1 |
| Al-Agha, R | 1 |
| Mattig, I | 1 |
| Franke, MR | 1 |
| Pschowski, R | 1 |
| Brand, A | 1 |
| Stangl, K | 1 |
| Knebel, F | 1 |
| Dreger, H | 1 |
| Buchanan-Hughes, A | 1 |
| Pashley, A | 1 |
| Feuilly, M | 1 |
| Marteau, F | 1 |
| Pritchard, DM | 2 |
| Singh, S | 1 |
| Bergsten, J | 1 |
| Flachskampf, FA | 1 |
| Lundin, L | 2 |
| Öhagen, P | 1 |
| Albåge, A | 1 |
| Dobson, R | 3 |
| Burgess, MI | 2 |
| Banks, M | 1 |
| Vora, J | 1 |
| Valle, JW | 3 |
| Wong, C | 1 |
| Chadwick, C | 2 |
| George, K | 1 |
| Keevil, B | 2 |
| Adaway, J | 1 |
| Ardill, JE | 1 |
| Anthoney, A | 1 |
| Hofmann, U | 1 |
| Poston, GJ | 1 |
| Cuthbertson, DJ | 3 |
| Jones, J | 1 |
| Poston, GP | 1 |
| Rambocas, N | 1 |
| Murphy, D | 1 |
| Adaway, JE | 1 |
| Walsh, J | 1 |
| Monaghan, PJ | 1 |
| Trainer, PJ | 1 |
| Keevil, BG | 1 |
| Jahagirdar, V | 1 |
| Kamal, A | 1 |
| Steeds, R | 1 |
| Ayuk, J | 1 |
| Jackson, LN | 1 |
| Chen, LA | 1 |
| Larson, SD | 1 |
| Silva, SR | 1 |
| Rychahou, PG | 1 |
| Boor, PJ | 1 |
| Li, J | 1 |
| Defreitas, G | 1 |
| Stafford, WL | 1 |
| Townsend, CM | 1 |
| Evers, BM | 1 |
| Mansencal, N | 1 |
| Mitry, E | 1 |
| Bachet, JB | 1 |
| Rougier, P | 1 |
| Dubourg, O | 1 |
| Bhattacharyya, S | 1 |
| Toumpanakis, C | 1 |
| Chilkunda, D | 1 |
| Caplin, ME | 1 |
| Davar, J | 1 |
| Lu, KJ | 1 |
| Rathi, V | 1 |
| Calafiore, P | 1 |
| Smith, G | 1 |
| Srivastava, PM | 1 |
| Eapen, DJ | 1 |
| Clements, S | 1 |
| Block, P | 1 |
| Sperling, L | 1 |
| Møller, JE | 1 |
| Connolly, HM | 1 |
| Rubin, J | 2 |
| Seward, JB | 2 |
| Modesto, K | 1 |
| Pellikka, PA | 2 |
| Zuetenhorst, JM | 2 |
| Bonfrer, JM | 1 |
| Korse, CM | 1 |
| Bakker, R | 1 |
| van Tinteren, H | 1 |
| Taal, BG | 2 |
| van der Horst-Schrivers, AN | 1 |
| Wymenga, AN | 1 |
| de Vries, EG | 1 |
| Fox, DJ | 1 |
| Khattar, RS | 1 |
| Rorstad, O | 1 |
| Musunuru, S | 1 |
| Carpenter, JE | 1 |
| Sippel, RS | 2 |
| Kunnimalaiyaan, M | 1 |
| Chen, H | 2 |
| Jaber, WA | 1 |
| Klarich, KW | 1 |
| Taber, M | 1 |
| Askenazi, J | 1 |
| Ribner, H | 1 |
| Kumar, S | 1 |
| Lesch, M | 1 |
| Tajik, AJ | 1 |
| Khandheria, BK | 1 |
| Callahan, JA | 1 |
| Pitot, HC | 1 |
| Kvols, LK | 1 |
| Denney, WD | 1 |
| Kemp, WE | 1 |
| Anthony, LB | 1 |
| Oates, JA | 1 |
| Byrd, BF | 1 |
| Kinney, MA | 1 |
| Warner, ME | 1 |
| Nagorney, DM | 1 |
| Schroeder, DR | 1 |
| Maxson, PM | 1 |
| Warner, MA | 1 |
| Salyer, DC | 1 |
| Eggleston, JC | 1 |
| May, B | 1 |
| Arora, RR | 1 |
| Warner, RR | 1 |
| Silva, CE | 1 |
| Ortiz, J | 1 |
| Lima, AB | 1 |
| Matsumoto, AY | 1 |
| Marotta, RH | 1 |
| Monaco, CA | 1 |
| Barretto, AC | 1 |
| Feldman, JM | 1 |
| Norheim, I | 1 |
| Landelius, J | 1 |
| Oberg, K | 1 |
| Theodorsson-Norheim, E | 1 |
| Himelman, RB | 1 |
| Schiller, NB | 1 |
| von Studnitz, W | 1 |
5 reviews available for hydroxyindoleacetic acid and Carcinoid Heart Disease
| Article | Year |
|---|---|
Carcinoid Heart Disease: Prognostic Value of 5-Hydroxyindoleacetic Acid Levels and Impact on Survival: A Systematic Literature Review.
Topics: Carcinoid Heart Disease; Female; Humans; Hydroxyindoleacetic Acid; Male; Malignant Carcinoid Syndrom | 2021 |
Carcinoid heart disease: presentation, diagnosis, and management.
Topics: Aged; Carcinoid Heart Disease; Cardiology; Catheterization; Echocardiography; Education, Medical, Co | 2004 |
Prognostic indicators for carcinoid neuroendocrine tumors of the gastrointestinal tract.
Topics: Biomarkers, Tumor; Carcinoid Heart Disease; Carcinoid Tumor; Chromogranin A; Chromogranins; Gastroin | 2005 |
Carcinoid tumors.
Topics: Antineoplastic Agents, Hormonal; Appendiceal Neoplasms; Carcinoid Heart Disease; Carcinoid Tumor; Hu | 2006 |
[Carcinoid: diagnosis and therapy].
Topics: Aprotinin; Bradykinin; Carcinoid Heart Disease; Carcinoid Tumor; Cyproheptadine; Diagnosis, Differen | 1975 |
31 other studies available for hydroxyindoleacetic acid and Carcinoid Heart Disease
| Article | Year |
|---|---|
Arterial function, biomarkers, carcinoid syndrome and carcinoid heart disease in patients with small intestinal neuroendocrine tumours.
Topics: Biomarkers; Carcinoid Heart Disease; Carcinoid Tumor; Cross-Sectional Studies; Humans; Hydroxyindole | 2022 |
A Case of Primary Insular Ovarian Carcinoid Tumor with Hyperandrogenism and Carcinoid Heart Disease.
Topics: Adult; Carcinoid Heart Disease; Carcinoid Tumor; Chromogranin A; Chromogranins; Female; Humans; Hydr | 2022 |
Prevalence, one-year-incidence and predictors of carcinoid heart disease.
Topics: Carcinoid Heart Disease; Humans; Hydroxyindoleacetic Acid; Incidence; Prevalence; Prospective Studie | 2023 |
A 33-year follow-up after valvular surgery for carcinoid heart disease.
Topics: Carcinoid Heart Disease; Follow-Up Studies; Heart Valve Prosthesis Implantation; Heart Valves; Human | 2022 |
The association of a panel of biomarkers with the presence and severity of carcinoid heart disease: a cross-sectional study.
Topics: Aged; Biomarkers; Carcinoid Heart Disease; Cross-Sectional Studies; Female; Humans; Hydroxyindoleace | 2013 |
Determination of the optimal echocardiographic scoring system to quantify carcinoid heart disease.
Topics: Aged; Aged, 80 and over; Biomarkers; Carcinoid Heart Disease; Echocardiography; Feasibility Studies; | 2014 |
An unusual ovarian cyst.
Topics: Aged; Carcinoid Heart Disease; Carcinoid Tumor; Female; Humans; Hydroxyindoleacetic Acid; Ovarian Cy | 2014 |
Serum and plasma 5-hydroxyindoleacetic acid as an alternative to 24-h urine 5-hydroxyindoleacetic acid measurement.
Topics: Aged; Biomarkers; Carcinoid Heart Disease; Carcinoid Tumor; Case-Control Studies; Female; Glomerular | 2016 |
Metastatic small bowel neuroendocrine tumour with bilateral carcinoid heart disease.
Topics: Carcinoid Heart Disease; Chromogranin A; Endocarditis; Fatal Outcome; Female; Humans; Hydroxyindolea | 2016 |
Development and characterization of a novel in vivo model of carcinoid syndrome.
Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineo | 2009 |
Echocardiographic follow-up of treated patients with carcinoid syndrome.
Topics: Aged; Biomarkers; Carcinoid Heart Disease; Echocardiography; Female; Follow-Up Studies; Heart Neopla | 2010 |
Risk factors for the development and progression of carcinoid heart disease.
Topics: Aged; Biomarkers, Tumor; Carcinoid Heart Disease; Disease Progression; Echocardiography; Female; Fol | 2011 |
Multimodality imaging in an unusual case of palpitations and right heart failure.
Topics: Aged; Carcinoid Heart Disease; Fatal Outcome; Female; Fluorodeoxyglucose F18; Heart Failure; Heart N | 2011 |
Metastatic carcinoid disease inducing coronary vasospasm.
Topics: Aged; Alcohol Drinking; Antineoplastic Agents, Hormonal; Biomarkers; Carcinoid Heart Disease; Carcin | 2012 |
Factors associated with progression of carcinoid heart disease.
Topics: Aged; Carcinoid Heart Disease; Disease Progression; Echocardiography, Doppler; Female; Heart Valve D | 2003 |
Carcinoid heart disease: the role of urinary 5-hydroxyindoleacetic acid excretion and plasma levels of atrial natriuretic peptide, transforming growth factor-beta and fibroblast growth factor.
Topics: Adult; Aged; Atrial Natriuretic Factor; Carcinoid Heart Disease; Female; Fibroblast Growth Factors; | 2003 |
Carcinoid heart disease.
Topics: Carcinoid Heart Disease; Disease Progression; Humans; Hydroxyindoleacetic Acid; Selection Bias; Soma | 2003 |
Carcinoid heart disease.
Topics: Area Under Curve; Carcinoid Heart Disease; Disease Progression; Female; Humans; Hydroxyindoleacetic | 2003 |
A mouse model of carcinoid syndrome and heart disease.
Topics: Animals; Carcinoid Heart Disease; Disease Models, Animal; Hydroxyindoleacetic Acid; Liver Neoplasms, | 2005 |
Images in cardiovascular medicine. Carcinoid heart disease.
Topics: Bioprosthesis; Carcinoid Heart Disease; Echocardiography, Doppler; Humans; Hydroxyindoleacetic Acid; | 2006 |
The tricuspid valve in carcinoid syndrome. An echocardiographic study.
Topics: Carcinoid Heart Disease; Cardiac Catheterization; Echocardiography; Humans; Hydroxyindoleacetic Acid | 1983 |
Carcinoid heart disease. Clinical and echocardiographic spectrum in 74 patients.
Topics: Carcinoid Heart Disease; Dyspnea; Echocardiography, Doppler; Electrocardiography; Female; Heart Neop | 1993 |
Echocardiographic and biochemical evaluation of the development and progression of carcinoid heart disease.
Topics: Adult; Aged; Carcinoid Heart Disease; Disease Progression; Echocardiography; Echocardiography, Doppl | 1998 |
Perianaesthetic risks and outcomes of abdominal surgery for metastatic carcinoid tumours.
Topics: Abdominal Neoplasms; Adult; Aged; Antineoplastic Agents, Hormonal; Carcinoid Heart Disease; Carcinoi | 2001 |
Oat cell carcinoma of the bronchus and the carcinoid syndrome.
Topics: Aged; Bronchi; Bronchial Neoplasms; Carcinoid Heart Disease; Carcinoid Tumor; Carcinoma, Small Cell; | 1975 |
Do indole markers predict carcinoid heart disease?
Topics: Adult; Aged; Aortic Valve; Carcinoid Heart Disease; Female; Heart Valve Diseases; Humans; Hydroxyind | 1986 |
[The echocardiogram in the carcinoid heart syndrome. A case report].
Topics: Adult; Blood Pressure; Carcinoid Heart Disease; Echocardiography; Female; Humans; Hydroxyindoleaceti | 1986 |
Carcinoid tumors and syndrome.
Topics: 5-Hydroxytryptophan; Carcinoembryonic Antigen; Carcinoid Heart Disease; Carcinoid Tumor; Diagnosis, | 1987 |
Carcinoid heart disease: relationship of circulating vasoactive substances to ultrasound-detectable cardiac abnormalities.
Topics: Adult; Aged; Aged, 80 and over; Carcinoid Heart Disease; Female; Heart Diseases; Humans; Hydroxyindo | 1988 |
Clinical and echocardiographic comparison of patients with the carcinoid syndrome with and without carcinoid heart disease.
Topics: Adult; Aged; Carcinoid Heart Disease; Echocardiography; Female; Heart Valve Diseases; Humans; Hydrox | 1989 |
[Proceedings: Tryptophan hydroxylase inhibition as therapy for carcinoid tumors].
Topics: Carcinoid Heart Disease; Carcinoid Tumor; Constipation; Diarrhea; Eosinophilia; Fenclonine; Humans; | 1972 |