hydroxyindoleacetic acid has been researched along with Brain Ischemia in 24 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of citalopram, a serotonin (5-HT) reuptake inhibitor, on cerebral blood flow (CBF) and concentration of 5-HT and its metabolite were investigated in spontaneously hypertensives rats (SHR) subjected to forebrain ischemia." | 7.69 | Citalopram, a serotonin reuptake inhibitor, and brain ischemia in SHR. ( Fujishima, M; Ibayashi, S; Izumi, J; Nagao, T; Sadoshima, S, 1995) |
| "In rats with cerebral ischemia, a low dose (10 mg/kg, i." | 5.27 | Effects of idebenone (CV-2619) on metabolism of monoamines, especially serotonin, in the brain of normal rats and rats with cerebral ischemia. ( Kakihana, M; Nagai, Y; Nagaoka, A; Nagawa, Y; Narumi, S; Yamazaki, N, 1985) |
| "The effects of citalopram, a serotonin (5-HT) reuptake inhibitor, on cerebral blood flow (CBF) and concentration of 5-HT and its metabolite were investigated in spontaneously hypertensives rats (SHR) subjected to forebrain ischemia." | 3.69 | Citalopram, a serotonin reuptake inhibitor, and brain ischemia in SHR. ( Fujishima, M; Ibayashi, S; Izumi, J; Nagao, T; Sadoshima, S, 1995) |
| "For understanding of the role of monoamines in cerebral ischemia, 3-methoxy-4-hydroxyphenylglycol (MHPG), hydroxyindoleacetic acid (5HIAA) homovanillic acid (HVA) the three major monoamine metabolites in CSF of 33 patients and 18 controls were measured with high-performance liquid chromatography." | 3.68 | [The changes of monoamine metabolites in CSF of patients with cerebral stroke]. ( Tang, HZ, 1991) |
| "Rat striatal extracellular fluid levels of dopamine, serotonin, 3-methoxytyramine (3-MT), 3,4-dihydroxyphenylacetic acid (DOPAC), homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA) were measured before, during and after transient, global cerebral ischemia in awake rats using in vivo brain microdialysis." | 3.67 | Effects of transient, global, cerebral ischemia on striatal extracellular dopamine, serotonin and their metabolites. ( Clemens, JA; Phebus, LA, 1989) |
| "To clarify the rule of monoamine in cerebral ischemia, 3-methoxy-4-hydroxyphenylglycol (MHPG), 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) in cerebrospinal fluid (CSF) of 33 patients and 18 controls were measured with high performance liquid chromatography." | 3.67 | Monoamine metabolites in cerebrospinal fluid during acute cerebral ischemia. ( Huang, YQ; Lu, XF; Ou, YS; Tang, HZ; Wang, KJ, 1989) |
| "Vannucci, Experimental biology of cerebral hypoxia-ischemia: relation to perinatal brain damage, Pediatr." | 1.30 | Anoxic and hypoxic immature rat model for measurement of monoamine using in vivo microdialysis. ( Ishida, A; Nakajima, W; Takada, G, 1999) |
| "In rats with cerebral ischemia, idebenone (10 mg/kg, i." | 1.28 | Effects of idebenone on metabolism of monoamines and cyclic AMP formation in rats. ( Kakihana, M; Nagai, Y; Nagaoka, A; Nagawa, Y; Narumi, S; Yamazaki, N, 1989) |
| "Our results indicate that during cerebral ischemia a large increase in extracellular dopamine concentration in the caudate nucleus occurs, probably as a result of energy failure of the cell membranes." | 1.27 | Striatal dopamine in acute cerebral ischemia of stroke-resistant rats. ( Kawano, T; Miyake, H; Mori, K; Tsutsumi, K, 1988) |
| "In rats with cerebral ischemia, a low dose (10 mg/kg, i." | 1.27 | Effects of idebenone (CV-2619) on metabolism of monoamines, especially serotonin, in the brain of normal rats and rats with cerebral ischemia. ( Kakihana, M; Nagai, Y; Nagaoka, A; Nagawa, Y; Narumi, S; Yamazaki, N, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (54.17) | 18.7374 |
| 1990's | 10 (41.67) | 18.2507 |
| 2000's | 1 (4.17) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mitsuyo, T | 1 |
| Adachi, N | 1 |
| Yorozuya, T | 1 |
| Tabo, E | 1 |
| Nagaro, T | 1 |
| Arai, T | 1 |
| Pau, A | 1 |
| Sehrobundt Viale, E | 1 |
| Turtas, S | 1 |
| Jellinger, K | 1 |
| Riederer, P | 1 |
| Stelmasiak, Z | 1 |
| Kogure, K | 1 |
| Nagao, T | 1 |
| Ibayashi, S | 1 |
| Sadoshima, S | 1 |
| Izumi, J | 1 |
| Fujishima, M | 1 |
| Takagi, N | 1 |
| Miyake, K | 1 |
| Ohiwa, A | 1 |
| Nukaga, R | 1 |
| Takeo, S | 1 |
| Thaminy, S | 1 |
| Bellissant, E | 1 |
| Maginn, M | 1 |
| Decombe, R | 1 |
| Allain, H | 1 |
| Bentué-Ferrer, D | 1 |
| Nakajima, W | 1 |
| Ishida, A | 1 |
| Takada, G | 1 |
| Globus, MY | 1 |
| Wester, P | 1 |
| Busto, R | 1 |
| Dietrich, WD | 1 |
| Luthman, J | 1 |
| Lindqvist, E | 1 |
| Dell'Anna, E | 1 |
| Kojima, H | 1 |
| Shiotani, T | 1 |
| Tachizawa, H | 1 |
| Olson, L | 1 |
| Haba, K | 1 |
| Ogawa, N | 1 |
| Asanuma, M | 1 |
| Hirata, H | 1 |
| Mori, A | 1 |
| Heyes, MP | 1 |
| Nowak, TS | 1 |
| Tang, HZ | 2 |
| Bao, WL | 1 |
| Sun, FY | 1 |
| Tong, JF | 1 |
| Zhang, LM | 1 |
| Zhang, AZ | 1 |
| Ferrarese, C | 1 |
| Bassi, S | 1 |
| Frattola, L | 1 |
| Locatelli, P | 1 |
| Piolti, R | 1 |
| Trabucchi, M | 1 |
| Weinberger, J | 1 |
| Nieves-Rosa, J | 1 |
| Ogura, K | 1 |
| Shibuya, M | 1 |
| Kanamori, M | 1 |
| Suzuki, Y | 1 |
| Harada, T | 1 |
| Okada, T | 1 |
| Tanoi, C | 1 |
| Kageyama, N | 1 |
| Kawano, T | 2 |
| Miyake, H | 2 |
| Tsutsumi, K | 2 |
| Mori, K | 2 |
| Phebus, LA | 1 |
| Clemens, JA | 1 |
| Nagai, Y | 2 |
| Narumi, S | 2 |
| Kakihana, M | 2 |
| Yamazaki, N | 2 |
| Nagaoka, A | 2 |
| Nagawa, Y | 2 |
| Lu, XF | 1 |
| Wang, KJ | 1 |
| Ou, YS | 1 |
| Huang, YQ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Study of F-18 Paclitaxel (FPAC) PET for Evaluating Drug Delivery of Solid Tumors in Breast, Lung, Renal, and Adrenal Cancers[NCT01086696] | Early Phase 1 | 6 participants (Actual) | Interventional | 2010-03-09 | Terminated | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
24 other studies available for hydroxyindoleacetic acid and Brain Ischemia
| Article | Year |
|---|---|
Facilitation of ischemia-induced release of dopamine and neuronal damage by dexamethasone in the rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenal Cortex Hormones; Animals; Biogenic Monoamines; Blood Pressur | 2003 |
Effect of omental transposition on to the brain on the cortical content of norepinephrine, dopamine, 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in experimental cerebral ischaemia.
Topics: Animals; Biogenic Amines; Brain; Brain Ischemia; Cerebral Cortex; Dopamine; Hydroxyindoleacetic Acid | 1982 |
[Central neurotransmitters in cerebral ischemia and stroke].
Topics: Animals; Blood-Brain Barrier; Brain Edema; Brain Ischemia; Cerebral Infarction; Cerebrovascular Diso | 1983 |
Effect of ischemia on monoamine metabolism. Brain monoamine metabolites in cerebrospinal fluid of patients with recent cerebral infarction.
Topics: Aged; Brain Ischemia; Cerebral Infarction; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Ac | 1982 |
[Cerebral ischemia and changes in the brain monoamines].
Topics: Animals; Biogenic Amines; Brain; Brain Ischemia; Cyclic AMP; Dopamine; Epinephrine; Hydroxyindoleace | 1983 |
Citalopram, a serotonin reuptake inhibitor, and brain ischemia in SHR.
Topics: Animals; Blood Pressure; Body Temperature; Brain Chemistry; Brain Ischemia; Cerebrovascular Circulat | 1995 |
Effects of delayed treatment with nafronyl oxalate on microsphere embolism-induced changes in monoamine levels of rat brain regions.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Brain; Brain Ischemia; Dopamine; Hydro | 1996 |
Effect of brain microdialysis on aminergic transmitter levels in repeated cerebral global transient ischemia in rat.
Topics: Amphetamines; Animals; Blood Glucose; Brain Chemistry; Brain Ischemia; Carotid Arteries; Cerebrovasc | 1996 |
Anoxic and hypoxic immature rat model for measurement of monoamine using in vivo microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Brain; Brain Chemistry; Brain Ischemia; C | 1999 |
Ischemia-induced extracellular release of serotonin plays a role in CA1 neuronal cell death in rats.
Topics: Animals; Brain Ischemia; Cell Survival; Corpus Striatum; Dialysis; Extracellular Space; Hippocampus; | 1992 |
Effects of DM-9384, a pyrrolidone derivative, on ischemia-induced changes in the central monoamine systems.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Brain Chemistry; Brain Ischemia; Centr | 1992 |
Comparison of the effects of bifemelane hydrochloride, idebenone and indeloxazine hydrochloride on ischemia-induced changes in brain monoamines and their metabolites in gerbils.
Topics: Animals; Benzhydryl Compounds; Benzoquinones; Biogenic Monoamines; Brain Chemistry; Brain Ischemia; | 1992 |
Delayed increases in regional brain quinolinic acid follow transient ischemia in the gerbil.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Dopamin | 1990 |
[The changes of monoamine metabolites in CSF of patients with cerebral stroke].
Topics: Brain Ischemia; Cerebrovascular Disorders; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Ac | 1991 |
[Antagonistic effect of phencyclidine on cerebral ischemic damage of rats].
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Ischemia; Catecholamines; Cerebral Cortex; Dop | 1991 |
Different patterns of CSF neurotransmitter metabolism in patients with left or right hemispheric stroke.
Topics: Aged; Biogenic Amines; Brain Ischemia; Female; Functional Laterality; Homovanillic Acid; Humans; Hyd | 1986 |
Metabolism of monoamine neurotransmitters in the evolution of infarction in ischemic striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Brain Ischemia; Carotid Arteries; Cerebral | 1987 |
[Measurements of monoamine neurotransmitter metabolism by in vivo voltammetry].
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Brain; Brain Ischemia; Dopamine; Electrodi | 1987 |
[Sequential changes in dopamine and monoamine metabolites in ischemic rat caudate nucleus. In vivo dialysis coupled with high-performance liquid chromatography with electrochemical detection].
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Brain Ischemia; Caudate Nucleus; Chromatog | 1988 |
Striatal dopamine in acute cerebral ischemia of stroke-resistant rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Ischemia; Caudate Nucleus; Cerebrovascular Disorders; | 1988 |
Effects of transient, global, cerebral ischemia on striatal extracellular dopamine, serotonin and their metabolites.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Ischemia; Corpus Striatum; Dopamine; Extracellular Sp | 1989 |
Effects of idebenone on metabolism of monoamines and cyclic AMP formation in rats.
Topics: Animals; Benzoquinones; Biogenic Monoamines; Brain; Brain Ischemia; Cyclic AMP; Disease Models, Anim | 1989 |
Monoamine metabolites in cerebrospinal fluid during acute cerebral ischemia.
Topics: Aged; Biogenic Monoamines; Brain Ischemia; Electronic Data Processing; Female; Homovanillic Acid; Hu | 1989 |
Effects of idebenone (CV-2619) on metabolism of monoamines, especially serotonin, in the brain of normal rats and rats with cerebral ischemia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzoquinones; Biogenic Amines; Brain; Brain Ischemia; Chro | 1985 |