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hydroxyindoleacetic acid and Brain Disorders

hydroxyindoleacetic acid has been researched along with Brain Disorders in 41 studies

(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.

Research Excerpts

ExcerptRelevanceReference
"Of five comatose patients, two had cerebrovascular lesions and three had sustained head injury, and, in four of the five, the values of either one or both of HVA and 5-HIAA were low, but in the fifth case the 5-HIAA value was high."5.26Homovanillic acid and 5-hydroxyindoleacetic acid in the ventricular CSF of comatose patients with obstructive hydrocephalus. ( Inagawa, T; Ishikawa, S; Uozumi, T, 1980)
" For example, hypothesized serotonergic deficits in alcoholism, endorphin deficits in opioid dependence, and dopamine depletion in cocaine dependence all might predispose to depression."4.78Hypothesized neurochemical models for psychiatric syndromes in alcohol and drug dependence. ( Extein, IL; Gold, MS, 1993)
"Baseline concentrations of homovanillic acid (HVA), 5-hydroxyindole acetic acid (5-HIAA) and MHPG in the cerebrospinal fluid (CSF) were determined in 67 lobotomized and 30 non-lobotomized patients with chronic schizophrenia."3.66Monoamine metabolite levels in cerebrospinal fluid and brain atrophy in lobotomized schizophrenic patients. ( Hyyppä, S; Kampman, R; Myllylä, V; Ranta, P; Rimón, R; Roos, BE, 1979)
"Patients with hypoxic encephalopathy consisted of 5 with apallic syndrome and one patient with Lance-Adams syndrome."1.28[Study on the concentration of 5-hydroxyindoleacetic acid (5-HIAA) in the lumbar cerebrospinal fluid (CSF) in neurological diseases]. ( Fukuda, H; Hara, K; Kameyama, M; Nakamura, S; Udaka, F, 1989)
"In the group of 9 children with other psychoses, both the level of homovanillic acid and that of 5-hydroxy-indoleacetic acid was raised."1.27Childhood psychosis and monoamine metabolites in spinal fluid. ( Gillberg, C; Hamilton-Hellberg, C; Svennerholm, L, 1983)
"Of five comatose patients, two had cerebrovascular lesions and three had sustained head injury, and, in four of the five, the values of either one or both of HVA and 5-HIAA were low, but in the fifth case the 5-HIAA value was high."1.26Homovanillic acid and 5-hydroxyindoleacetic acid in the ventricular CSF of comatose patients with obstructive hydrocephalus. ( Inagawa, T; Ishikawa, S; Uozumi, T, 1980)
"The subjects with encephalopathy had raised plasma free tryptophan, CSF tryptophan, and CSF 5-hydroxyindoleacetic acid."1.26Cerebral transmitter precursors and metabolites in advanced renal disease. ( Callaghan, N; Curzon, G; Kantamaneni, BD; Murnaghan, D; Sullivan, PA, 1978)
"Two cases of idiopathic orthostatic hypotension are reported, one associated with striato-nigral degeneration (case 1) and the other with Lewy body parkinsonism (case 2)."1.25Idiopathic orthostatic hypotension. Biochemical and pathologic observations in 2 cases. ( Forno, LS; Langston, JW; Schober, R, 1975)

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199033 (80.49)18.7374
1990's6 (14.63)18.2507
2000's1 (2.44)29.6817
2010's1 (2.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Winter, C1
Djodari-Irani, A1
Sohr, R1
Morgenstern, R1
Feldon, J1
Juckel, G1
Meyer, U1
Willemsen, MA1
Verbeek, MM1
Kamsteeg, EJ1
de Rijk-van Andel, JF1
Aeby, A1
Blau, N1
Burlina, A1
Donati, MA1
Geurtz, B1
Grattan-Smith, PJ1
Haeussler, M1
Hoffmann, GF1
Jung, H1
de Klerk, JB1
van der Knaap, MS1
Kok, F1
Leuzzi, V1
de Lonlay, P1
Megarbane, A1
Monaghan, H1
Renier, WO1
Rondot, P1
Ryan, MM1
Seeger, J1
Smeitink, JA1
Steenbergen-Spanjers, GC1
Wassmer, E1
Weschke, B1
Wijburg, FA1
Wilcken, B1
Zafeiriou, DI1
Wevers, RA1
Inagawa, T1
Ishikawa, S1
Uozumi, T1
Takeoka, T1
Yamamoto, M1
Otsuki, S1
Miyake, K1
Namba, R1
Gillberg, C1
Svennerholm, L1
Hamilton-Hellberg, C1
Eichelman, B1
Extein, IL1
Gold, MS1
Gil-Nagel, A1
Morlán, L1
Balseiro, J1
García de Yébenes, J1
Cabello, A1
Martínez-Martín, P1
Sullivan, PA1
Murnaghan, D1
Callaghan, N1
Kantamaneni, BD2
Curzon, G2
Passouant, P1
Billiard, M1
Besset, A1
Renaud, B1
Rimón, R1
Roos, BE2
Kampman, R1
Hyyppä, S1
Ranta, P1
Myllylä, V1
Michel, D1
Tommasi, M1
Laurent, B1
Trillet, M1
Schott, B1
Bridges, PK1
Bartlett, JR1
Sepping, P1
Schober, R1
Langston, JW1
Forno, LS1
Siever, L1
Kraemer, H1
Sack, R1
Angwin, P1
Berger, P1
Zarcone, V1
Barchas, J1
Brodie, HK1
Gordon, K1
Statman, D1
Johnston, MV2
Robinson, TE2
Becker, JB1
Silverstein, FS2
Degrell, I1
Nagy, E1
Castañeda, E1
Whishaw, IQ1
O'Kusky, JR1
Boyes, BE1
Walker, DG1
McGeer, EG1
Kish, SJ1
Gilbert, JJ1
Chang, LJ1
Mirchandani, L1
Shannak, K1
Hornykiewicz, O1
Bradbury, AJ1
Costall, B1
Domeney, AM1
Testa, B1
Jenner, PG1
Marsden, CD1
Naylor, RJ1
Auerbach, S1
Zhou, F1
Jacobs, BL1
Azmitia, E1
Freund, HR1
Muggia-Sullam, M1
LaFrance, R1
Holroyde, J1
Fischer, JE1
Nakamura, S2
Greenberg, H1
Knutsen, CA1
Chandler, W1
Phillips, T1
Ensminger, WD1
Fukuda, H1
Hara, K1
Udaka, F1
Kameyama, M1
Scheinin, M1
Guilleminault, C1
Cathala, JP1
Castaigne, P1
Lakke, JP1
Korf, J1
van Praag, HM1
Minderhoud, JM1
Schut, T1
Garelis, E1
Sourkes, TL1
Himwich, WA1
Fukuyama, GS1
Massarotti, M1
Molnár, G1
Fodor, A1
Karczag, I1
Szilágyi, A1
Ujvárosi, I1
Lycke, E1
Meyers, KM1
Schaub, RG1
Ebadi, MS1
Bostad, R1
Pellegrino, RJ1
Samanin, R1
Gumulka, W1
Valzelli, L1
Wender, PH1
Epstein, RS1
Kopin, IJ1
Gordon, EK1
Kawiak, W1
O'Reilly, S1
Cooksey, B1

Reviews

4 reviews available for hydroxyindoleacetic acid and Brain Disorders

ArticleYear
[Neurotransmitters in the cerebrospinal fluid (author's transl)].
    No to shinkei = Brain and nerve, 1981, Volume: 33, Issue:9

    Topics: Acetylcholine; Adolescent; Adult; Age Factors; Aged; Animals; Biogenic Amines; Brain; Brain Diseases

1981
The limbic system and aggression in humans.
    Neuroscience and biobehavioral reviews, 1983,Fall, Volume: 7, Issue:3

    Topics: Aggression; Amygdala; Anticonvulsants; Brain Diseases; Brain Mapping; Brain Neoplasms; Electroenceph

1983
Hypothesized neurochemical models for psychiatric syndromes in alcohol and drug dependence.
    Journal of addictive diseases, 1993, Volume: 12, Issue:3

    Topics: Alcoholism; Brain Diseases; Cocaine; Comorbidity; Diagnosis, Dual (Psychiatry); Dopamine; Dopamine A

1993
Monoamine metabolites in human cerebrospinal fluid: indicators of neuronal activity?
    Medical biology, 1985, Volume: 63, Issue:1

    Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Biogenic Amines; Brain Diseases; Glycols; Homo

1985

Other Studies

37 other studies available for hydroxyindoleacetic acid and Brain Disorders

ArticleYear
Prenatal immune activation leads to multiple changes in basal neurotransmitter levels in the adult brain: implications for brain disorders of neurodevelopmental origin such as schizophrenia.
    The international journal of neuropsychopharmacology, 2009, Volume: 12, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Brain Diseases; Chromatography, High Press

2009
Tyrosine hydroxylase deficiency: a treatable disorder of brain catecholamine biosynthesis.
    Brain : a journal of neurology, 2010, Volume: 133, Issue:Pt 6

    Topics: Age of Onset; Amino Acid Metabolism, Inborn Errors; Brain; Brain Diseases; Catecholamines; Child, Pr

2010
Homovanillic acid and 5-hydroxyindoleacetic acid in the ventricular CSF of comatose patients with obstructive hydrocephalus.
    Journal of neurosurgery, 1980, Volume: 52, Issue:5

    Topics: Adolescent; Adult; Brain Diseases; Brain Neoplasms; Child; Coma; Craniopharyngioma; Ependymoma; Fema

1980
[Lumbar cerebrospinal fluid levels of GABA, HVA and 5HIAA in various patients with choreic movement and effects with isoniazid treatment].
    No to shinkei = Brain and nerve, 1983, Volume: 35, Issue:5

    Topics: Acanthocytes; Adult; Aged; Atrophy; Brain Diseases; Chorea; gamma-Aminobutyric Acid; Homovanillic Ac

1983
Childhood psychosis and monoamine metabolites in spinal fluid.
    Journal of autism and developmental disorders, 1983, Volume: 13, Issue:4

    Topics: Adolescent; Age Factors; Autistic Disorder; Brain Diseases; Cerebral Palsy; Child; Child, Preschool;

1983
[Neuro-acanthocytosis with associated myopathy. A case report].
    Neurologia (Barcelona, Spain), 1994, Volume: 9, Issue:4

    Topics: Acanthocytes; Adult; Basal Ganglia; Basophils; Brain Diseases; Cerebellum; Denervation; Homovanillic

1994
Cerebral transmitter precursors and metabolites in advanced renal disease.
    Journal of neurology, neurosurgery, and psychiatry, 1978, Volume: 41, Issue:7

    Topics: Adult; Aged; Brain; Brain Diseases; Fatty Acids, Nonesterified; Female; Homovanillic Acid; Humans; H

1978
Encephalopathy associated with bismuth salt ingestion and brain monoamines.
    International journal of neurology, 1979, Volume: 13, Issue:1-4

    Topics: Adult; Aged; Bismuth; Brain Diseases; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; M

1979
Monoamine metabolite levels in cerebrospinal fluid and brain atrophy in lobotomized schizophrenic patients.
    Annals of clinical research, 1979, Volume: 11, Issue:1

    Topics: Atrophy; Brain Diseases; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male;

1979
[Striato-nigral degeneration. A propos of 2 anatomo-clinical cases].
    Revue neurologique, 1976, Volume: 132, Issue:1

    Topics: Brain Diseases; Corpus Striatum; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male;

1976
Precursors and metabolites of 5-hydroxytryptamine and dopamine in the ventricular cerebrospinal fluid of psychiatric patients.
    Psychological medicine, 1976, Volume: 6, Issue:3

    Topics: Adult; Aged; Anxiety Disorders; Brain Diseases; Cerebral Ventricles; Depression; Female; Homovanilli

1976
Idiopathic orthostatic hypotension. Biochemical and pathologic observations in 2 cases.
    European neurology, 1975, Volume: 13, Issue:3

    Topics: 5-Hydroxytryptophan; Aged; Amines; Brain Diseases; Female; Ganglia, Autonomic; Humans; Hydroxyindole

1975
Gradients of biogenic amine metabolites in cerebrospinal fluid.
    Diseases of the nervous system, 1975, Volume: 36, Issue:1

    Topics: Alzheimer Disease; Amphetamine; Brain Diseases; Brain Neoplasms; Depression; Homovanillic Acid; Huma

1975
Transient hypoxia alters striatal catecholamine metabolism in immature brain: an in vivo microdialysis study.
    Journal of neurochemistry, 1990, Volume: 54, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Brain Diseases; Corpus Striatum; Dialysis

1990
Correlations between cisternal CSF and plasma concentrations of HVA, MHPG, 5-HIAA, DA, and NA.
    Biological psychiatry, 1990, May-15, Volume: 27, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Blood-Brain Barrier; Brain; Brain Diseases; Dopamine; Female; Glycol

1990
Changes in striatal dopamine neurotransmission assessed with microdialysis following recovery from a bilateral 6-OHDA lesion: variation as a function of lesion size.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1990, Volume: 10, Issue:6

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Brain Diseases; Corpus Striatum; Dialysis; Dop

1990
Cytomegalovirus infection of the developing brain alters catecholamine and indoleamine metabolism.
    Brain research, 1991, Sep-20, Volume: 559, Issue:2

    Topics: Animals; Biogenic Amines; Body Weight; Brain Chemistry; Brain Diseases; Catecholamines; Chromatograp

1991
Brain neurotransmitter abnormalities in neuronal intranuclear inclusion body disorder.
    Annals of neurology, 1985, Volume: 17, Issue:4

    Topics: Adolescent; Brain; Brain Diseases; Dopamine; Female; gamma-Aminobutyric Acid; Homovanillic Acid; Hum

1985
The toxic actions of MPTP and its metabolite MPP+ are not mimicked by analogues of MPTP lacking an N-methyl moiety.
    Neuroscience letters, 1985, Oct-24, Volume: 61, Issue:1-2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic

1985
Serotonin turnover in raphe neurons transplanted into rat hippocampus.
    Neuroscience letters, 1985, Oct-24, Volume: 61, Issue:1-2

    Topics: 5,7-Dihydroxytryptamine; Animals; Brain Diseases; Hippocampus; Hydroxyindoleacetic Acid; Male; Raphe

1985
Regional brain amino acid and neurotransmitter derangements during abdominal sepsis and septic encephalopathy in the rat. The effect of amino acid infusions.
    Archives of surgery (Chicago, Ill. : 1960), 1986, Volume: 121, Issue:2

    Topics: Amino Acids; Animals; Behavior, Animal; Brain; Brain Diseases; Cerebral Cortex; Corpus Striatum; Die

1986
[Neurotransmitters and degenerative diseases in the central nervous system].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1986, Volume: 23, Issue:1

    Topics: Acetylcholinesterase; Aged; Aging; Brain Diseases; Dementia; Dopamine; Homovanillic Acid; Humans; Hy

1986
Effects of intraventricular methotrexate on cerebrospinal fluid monoamine metabolites in rhesus monkeys.
    Cancer treatment reports, 1986, Volume: 70, Issue:10

    Topics: Animals; Brain Diseases; Cerebral Ventricles; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid;

1986
[Study on the concentration of 5-hydroxyindoleacetic acid (5-HIAA) in the lumbar cerebrospinal fluid (CSF) in neurological diseases].
    Rinsho shinkeigaku = Clinical neurology, 1989, Volume: 29, Issue:9

    Topics: Adult; Aged; Alzheimer Disease; Brain Diseases; Cerebrovascular Disorders; Female; Humans; Hydroxyin

1989
Effects of 5-hydroxytryptophan on sleep of a patient with a brain-stem lesion.
    Electroencephalography and clinical neurophysiology, 1973, Volume: 34, Issue:2

    Topics: 5-Hydroxytryptophan; Adult; Brain Diseases; Brain Stem; Electroencephalography; Electromyography; El

1973
Clinical significance of probenecid test.
    Lancet (London, England), 1973, Mar-17, Volume: 1, Issue:7803

    Topics: Brain Diseases; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Parkinson Disease; Phenylacetat

1973
Use of cerebrospinal fluid drawn at pneumoencephalography in the study of monoamine metabolism in man.
    Journal of neurology, neurosurgery, and psychiatry, 1974, Volume: 37, Issue:6

    Topics: Adolescent; Adult; Brain Diseases; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Homovani

1974
Genral neurophysiology (biochemical aspects).
    Progress in neurology and psychiatry, 1971, Volume: 26

    Topics: Age Factors; Animals; Bipolar Disorder; Blood-Brain Barrier; Brain; Brain Diseases; Cerebrovascular

1971
[Dosage of 5-HIAA in the lumbar cerebrospinal fluid of patients with intracranial hypertension (author's transl)].
    Rivista di patologia nervosa e mentale, 1974, Volume: 95, Issue:4

    Topics: Brain; Brain Diseases; Brain Injuries; Brain Neoplasms; Humans; Hydroxyindoleacetic Acid; Intracrani

1974
5-Hydroxyindoleacetic acid in cerebrospinal fluid.
    Acta medica Academiae Scientiarum Hungaricae, 1973, Volume: 30, Issue:3

    Topics: Adult; Age Factors; Brain Diseases; Brain Stem; Depression; Epilepsy; Humans; Hydroxyindoleacetic Ac

1973
Viral infections in the central nervous system and 5-hydroxytryptamine metabolism.
    Advances in biochemical psychopharmacology, 1974, Volume: 11, Issue:0

    Topics: Animals; Brain; Brain Diseases; Catecholamines; Coxsackievirus Infections; Dopamine; Encephalitis; H

1974
The relationship of serotonin to a motor disorder of Scottish terrier dogs.
    Life sciences, 1974, May-16, Volume: 14, Issue:10

    Topics: Animals; Brain; Brain Diseases; Caudate Nucleus; Cerebellum; Dogs; Hydroxyindoleacetic Acid; Hypotha

1974
Impairment of pyridoxal phosphate dependent metabolic reactions in a child with subacute necrotizing encephalopathy.
    Journal of neurology, neurosurgery, and psychiatry, 1969, Volume: 32, Issue:5

    Topics: 5-Hydroxytryptophan; Amines; Autopsy; Basal Ganglia; Brain Diseases; Carboxy-Lyases; Dopamine; Femal

1969
Reduced effect of morphine in midbrain raphe lesioned rats.
    European journal of pharmacology, 1970, Volume: 10, Issue:3

    Topics: Animals; Brain Chemistry; Brain Diseases; Female; Hydroxyindoleacetic Acid; Mesencephalon; Morphine;

1970
Urinary monoamine metabolites in children with minimal brain dysfunction.
    The American journal of psychiatry, 1971, Volume: 127, Issue:10

    Topics: Adolescent; Antidepressive Agents; Attention Deficit Disorder with Hyperactivity; Brain Damage, Chro

1971
Investigations on urinary excretion of 5-hydroxyindoleacetic acid (5-HIAA) in patients after cerebral stroke.
    Polish medical journal, 1968, Volume: 7, Issue:4

    Topics: Brain Diseases; Cerebral Hemorrhage; Cerebrovascular Disorders; Humans; Hydroxyindoleacetic Acid

1968
The relationship between 5-hydroxyindoles and catecholamines.
    Neurology, 1965, Volume: 15, Issue:12

    Topics: Blood-Brain Barrier; Brain Chemistry; Brain Diseases; Catecholamines; Dopamine; Female; Humans; Hydr

1965