hydroxyindoleacetic acid has been researched along with Borderline Personality Disorder in 4 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
Borderline Personality Disorder: A personality disorder marked by a pattern of instability of interpersonal relationships, self-image, and affects, and marked impulsivity beginning by early adulthood and present in a variety of contexts. (DSM-IV)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The cerebrospinal fluid concentrations of the monoamine metabolites 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA), 3-methoxy-4-hydroxyphenylglycol, and their ratios were studied in relation to the Diagnostic Interview for Borderline patients (DIB) evaluated retrospectively from hospital records for a sample of 202 patients participating in psychobiological programs on mood disorders." | 5.08 | CSF monoamine metabolites in relation to the diagnostic interview for borderline patients (DIB). ( Asberg, M; Chotai, J; Kullgren, G, 1998) |
| "In an earlier, separate study, the authors found that human aggression and suicide (a specific aggression-related behavior) were associated with lower levels of CSF 5-hydroxyindoleacetic acid (5-HIAA), a serotonin metabolite." | 3.66 | Aggression, suicide, and serotonin: relationships to CSF amine metabolites. ( Brown, GL; Bunney, WE; Ebert, MH; Goodwin, FK; Goyer, PF; Jimerson, DC; Klein, WJ, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brown, GL | 1 |
| Ebert, MH | 1 |
| Goyer, PF | 1 |
| Jimerson, DC | 1 |
| Klein, WJ | 1 |
| Bunney, WE | 1 |
| Goodwin, FK | 1 |
| Chotai, J | 2 |
| Kullgren, G | 2 |
| Asberg, M | 2 |
| Salander Renberg, E | 1 |
| Gardner, DL | 1 |
| Lucas, PB | 1 |
| Cowdry, RW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Pimavanserin on Aggression and Social Cognition.[NCT05895513] | Phase 2 | 35 participants (Anticipated) | Interventional | 2024-01-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for hydroxyindoleacetic acid and Borderline Personality Disorder
| Article | Year |
|---|---|
CSF monoamine metabolites in relation to the diagnostic interview for borderline patients (DIB).
Topics: Biogenic Monoamines; Borderline Personality Disorder; Homovanillic Acid; Humans; Hydroxyindoleacetic | 1998 |
3 other studies available for hydroxyindoleacetic acid and Borderline Personality Disorder
| Article | Year |
|---|---|
Aggression, suicide, and serotonin: relationships to CSF amine metabolites.
Topics: Adolescent; Adult; Aggression; Antisocial Personality Disorder; Borderline Personality Disorder; Bra | 1982 |
Season of birth variations in dimensions of functioning evaluated by the diagnostic interview for borderline patients.
Topics: Anxiety Disorders; Biogenic Monoamines; Birth Certificates; Borderline Personality Disorder; Homovan | 2000 |
CSF metabolites in borderline personality disorder compared with normal controls.
Topics: Adult; Borderline Personality Disorder; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleace | 1990 |