hydroxyindoleacetic acid has been researched along with Bipolar Disorder in 143 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Activation of indoleamine 2-3 dioxygenase following a pro-inflammatory state could reduce the amount of tryptophan converted to serotonin and increase the production of tryptophan catabolites such as kynurenic acid, an antagonist of ionotropic excitatory aminoacid receptors, whose levels are reduced in bipolar disorder." | 7.88 | Kynurenine pathway and white matter microstructure in bipolar disorder. ( Benedetti, F; Bollettini, I; Colombo, C; Grillitsch, D; Locatelli, C; Mazza, E; Myint, AM; Poletti, S; Schüetze, G; Schwarz, M, 2018) |
| "Low gamma-aminobutyric acid (GABA) is implicated in both anxiety and depression pathophysiology." | 7.80 | Anxiety in major depression and cerebrospinal fluid free gamma-aminobutyric acid. ( Boldrini, M; Cooper, TB; Currier, D; Ellis, SP; Malone, KM; Mann, JJ; Oquendo, MA; Sullivan, G; Watson, KT; Xie, S, 2014) |
| "In a mixed bipolar disorder patient, DST-positive, treated with neuroleptics and antidepressants, the addition of clonidine (up to 0." | 7.67 | Clonidine in the treatment of mixed bipolar disorder. ( Kontaxakis, V; Markianos, M; Markidis, M; Stefanis, C, 1989) |
| " Activation of indoleamine 2-3 dioxygenase following a pro-inflammatory state could reduce the amount of tryptophan converted to serotonin and increase the production of tryptophan catabolites such as kynurenic acid, an antagonist of ionotropic excitatory aminoacid receptors, whose levels are reduced in bipolar disorder." | 3.88 | Kynurenine pathway and white matter microstructure in bipolar disorder. ( Benedetti, F; Bollettini, I; Colombo, C; Grillitsch, D; Locatelli, C; Mazza, E; Myint, AM; Poletti, S; Schüetze, G; Schwarz, M, 2018) |
| "Low gamma-aminobutyric acid (GABA) is implicated in both anxiety and depression pathophysiology." | 3.80 | Anxiety in major depression and cerebrospinal fluid free gamma-aminobutyric acid. ( Boldrini, M; Cooper, TB; Currier, D; Ellis, SP; Malone, KM; Mann, JJ; Oquendo, MA; Sullivan, G; Watson, KT; Xie, S, 2014) |
| "In 8 cases of typical neuroleptic malignant syndrome (NMS), homovanillic acid (HVA), 5-hydroxyindole acetic acid (5-HIAA), noradrenaline (NA), and 3-methoxy-4-hydroxyphenylethyleneglycol (MHPG) levels in the cerebrospinal fluid (CSF) were assayed during both the active phase of NMS and after recovery." | 3.68 | Neuroleptic malignant syndrome: a study of CSF monoamine metabolism. ( Ishiguro, T; Nisijima, K, 1990) |
| "Lateral ventricle enlargement in schizophrenia has been positively correlated with poor premorbid competence, negative symptoms, and poor treatment response and negatively correlated with concentrations of homovanillic acid (HVA), a dopaminergic metabolite." | 3.68 | Lateral ventricle-brain ratio and balance between CSF HVA and 5-HIAA in schizophrenia. ( Caudle, J; Eccard, M; Jewart, RD; Lewine, RR; Pollard, W; Risby, E; Risch, SC; Stipetic, M, 1991) |
| "CSF levels of radioreceptorassayed endorphins Fraction I (EndFI, n = 92) and homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA) (n = 118) were measured in patients with major depressive disorders according to Research Diagnostic Criteria (18% were psychotic; 11% hallucinated during the peak of the depressive episode)." | 3.67 | Hallucinations in patients with major depression. Interactions between CSF monoaminergic and endorphinergic indices. ( Agren, H; Terenius, L, 1985) |
| "The effects of electroconvulsive therapy (ECT) on sleep and cerebrospinal fluid (CSF) 5-hydroxyindoleacetic acid (5HIAA) and homovanillic acid (HVA) were studied in 11 male patients suffering from major depressive disorders severe enough to require ECT." | 3.67 | Effects of ECT on sleep and CSF biogenic amines in affective illness. ( Desmedt, D; Hoffmann, G; Kerkhofs, M; Linkowski, P; Mendlewicz, J, 1985) |
| "In a mixed bipolar disorder patient, DST-positive, treated with neuroleptics and antidepressants, the addition of clonidine (up to 0." | 3.67 | Clonidine in the treatment of mixed bipolar disorder. ( Kontaxakis, V; Markianos, M; Markidis, M; Stefanis, C, 1989) |
| "5-Hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) were measured in the spinal fluid of 45 women hospitalized in a psychiatric department for major depression (14 cases), schizophrenia (18 cases) and alcohol dependence (13 cases)." | 3.66 | Relationship between cerebrospinal fluid amine metabolites, neuroendocrine findings and personality dimensions (Marke-Nyman scale factors) in psychiatric patients. ( Arató, M; Banki, CM, 1983) |
| "The metabolites of serotonin, dopamine, and norepinephrine, 5-hydroxyindoleacetic acid (5HIAA), homovanillic acid (HVA), and 3-methoxy-4-hydroxy-phenylethylene glycol (MHPG), respectively, were studied in cerebrospinal fluid of patients with acute schizophrenia." | 3.65 | Cerebrospinal fluid amine metabolites in acute schizophrenia. ( Carpenter, WT; Fink, E; Goodwin, FK; Post, RM, 1975) |
| "One hundred nine bipolar, 324 major depressive disorder, and 130 healthy volunteers were genotyped for the rs4131347 (-C8347G) promoter SNP." | 1.35 | No association between a TPH2 promoter polymorphism and mood disorders or monoamine turnover. ( Brent, D; Currier, D; Galfalvy, H; Greenhill, L; Huang, YY; Mann, JJ; Murphy, L; Oquendo, M, 2008) |
| "Responders with bipolar depression had smaller reductions in MHPG levels than did responders with unipolar depression." | 1.27 | Effects of amitriptyline and imipramine on brain amine neurotransmitter metabolites in cerebrospinal fluid. ( Bowden, CL; Davis, JM; Hanin, I; Koslow, SH; Maas, JW; Robins, E, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 118 (82.52) | 18.7374 |
| 1990's | 11 (7.69) | 18.2507 |
| 2000's | 9 (6.29) | 29.6817 |
| 2010's | 5 (3.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Knorr, U | 1 |
| Simonsen, AH | 1 |
| Zetterberg, H | 1 |
| Blennow, K | 2 |
| Hasselbalch, SG | 1 |
| Kessing, LV | 1 |
| Pompili, M | 1 |
| Lionetto, L | 1 |
| Curto, M | 1 |
| Forte, A | 1 |
| Erbuto, D | 1 |
| Montebovi, F | 1 |
| Seretti, ME | 1 |
| Berardelli, I | 1 |
| Serafini, G | 1 |
| Innamorati, M | 1 |
| Amore, M | 1 |
| Baldessarini, RJ | 1 |
| Girardi, P | 1 |
| Simmaco, M | 1 |
| Mann, JJ | 4 |
| Oquendo, MA | 3 |
| Watson, KT | 1 |
| Boldrini, M | 1 |
| Malone, KM | 1 |
| Ellis, SP | 1 |
| Sullivan, G | 1 |
| Cooper, TB | 1 |
| Xie, S | 1 |
| Currier, D | 3 |
| Poletti, S | 1 |
| Myint, AM | 1 |
| Schüetze, G | 1 |
| Bollettini, I | 1 |
| Mazza, E | 1 |
| Grillitsch, D | 1 |
| Locatelli, C | 1 |
| Schwarz, M | 1 |
| Colombo, C | 1 |
| Benedetti, F | 1 |
| Galfalvy, H | 2 |
| Huang, YY | 3 |
| Jokinen, J | 2 |
| Nordström, AL | 1 |
| Nordström, P | 3 |
| Goldstein, TR | 1 |
| Rydén, E | 1 |
| Johansson, C | 1 |
| Landén, M | 1 |
| Asellus, P | 1 |
| BURGERMEISTER, JJ | 1 |
| DICK, P | 1 |
| GARONNE, G | 1 |
| GUGGISBERG, M | 1 |
| TISSOT, R | 3 |
| PELICIER, Y | 1 |
| Bell, CJ | 1 |
| Hood, SD | 1 |
| Nutt, DJ | 1 |
| Sher, L | 1 |
| Carballo, JJ | 1 |
| Grunebaum, MF | 1 |
| Burke, AK | 1 |
| Zalsman, G | 1 |
| Murphy, L | 1 |
| Brent, D | 1 |
| Greenhill, L | 1 |
| Oquendo, M | 1 |
| McIntyre, RS | 1 |
| Muzina, DJ | 1 |
| Kemp, DE | 1 |
| Blank, D | 1 |
| Woldeyohannes, HO | 1 |
| Lofchy, J | 1 |
| Soczynska, JK | 1 |
| Banik, S | 1 |
| Konarski, JZ | 1 |
| Bourgeois, M | 1 |
| Henry, P | 1 |
| Post, RM | 11 |
| Jimerson, DC | 2 |
| Bunney, WE | 4 |
| Goodwin, FK | 14 |
| Leckman, JF | 1 |
| Cohen, DJ | 2 |
| Shaywitz, BA | 2 |
| Caparulo, BK | 1 |
| Heninger, GR | 2 |
| Bowers, MB | 6 |
| Rosenthal, NE | 2 |
| Davenport, Y | 1 |
| Cowdry, RW | 2 |
| Webster, MH | 1 |
| Anokhina, IP | 1 |
| Gamaleia, NB | 1 |
| Nakahara, T | 1 |
| Davis, KL | 1 |
| Hollister, LE | 1 |
| Mathé, AA | 1 |
| Davis, BM | 1 |
| Rothpearl, AB | 1 |
| Faull, KF | 2 |
| Hsieh, JY | 1 |
| Barchas, JD | 1 |
| Berger, PA | 1 |
| Agren, H | 5 |
| Johnson, GF | 1 |
| Taylor, MA | 1 |
| Abrams, R | 1 |
| Linnoila, M | 7 |
| Karoum, F | 1 |
| Potter, WZ | 3 |
| Uhde, TW | 1 |
| Oreland, L | 2 |
| Gerner, RH | 4 |
| Wilkins, JN | 1 |
| Wide, L | 1 |
| Swann, AC | 4 |
| Secunda, S | 1 |
| Davis, JM | 7 |
| Robins, E | 4 |
| Hanin, I | 3 |
| Koslow, SH | 7 |
| Maas, JW | 9 |
| Korf, J | 1 |
| van den Burg, W | 1 |
| van den Hoofdakker, RH | 1 |
| Banki, CM | 4 |
| Arató, M | 3 |
| Papp, Z | 2 |
| Kurcz, M | 1 |
| Bowden, CL | 4 |
| Javaid, J | 2 |
| Roy-Byrne, P | 1 |
| Rubinow, DR | 1 |
| Savard, R | 1 |
| Davis, D | 1 |
| Asberg, M | 2 |
| Bertilsson, L | 2 |
| Mårtensson, B | 1 |
| Scalia-Tomba, GP | 1 |
| Thorén, P | 1 |
| Träskman-Bendz, L | 3 |
| Terenius, L | 2 |
| von Knorring, L | 1 |
| Perris, C | 1 |
| Eisemann, M | 1 |
| Eriksson, U | 1 |
| Perris, H | 1 |
| Katz, MM | 5 |
| Gibbons, RL | 1 |
| Stokes, PE | 3 |
| Rainer, JD | 1 |
| Fairbanks, L | 1 |
| Anderson, GM | 1 |
| Young, JG | 1 |
| Scheinin, M | 3 |
| Hare, TA | 1 |
| Young, LT | 1 |
| Warsh, JJ | 3 |
| Kish, SJ | 1 |
| Shannak, K | 1 |
| Hornykeiwicz, O | 1 |
| Samuelsson, M | 1 |
| Aberg-Wistedt, A | 1 |
| Nordin, C | 1 |
| Markianos, M | 2 |
| Alevizos, B | 1 |
| Hatzimanolis, J | 1 |
| Stefanis, C | 2 |
| Frazer, A | 4 |
| Berman, N | 1 |
| Rudorfer, MV | 2 |
| Skwerer, RG | 1 |
| Leboyer, M | 1 |
| Quintin, P | 1 |
| Manivet, P | 1 |
| Varoquaux, O | 1 |
| Allilaire, JF | 1 |
| Launay, JM | 1 |
| Zametkin, AJ | 1 |
| Alter, MR | 1 |
| Yemini, T | 1 |
| Ravizza, L | 1 |
| Lingjaerde, O | 1 |
| van Praag, HM | 1 |
| de Haan, S | 1 |
| Roccatagliata, G | 1 |
| Albano, C | 1 |
| Cocito, L | 1 |
| Maffini, M | 1 |
| Paasche, I | 1 |
| Gillin, JC | 1 |
| Praag, HM | 1 |
| Takahashi, R | 2 |
| Muscettola, G | 1 |
| Claeys, MM | 1 |
| Markey, SP | 1 |
| Garver, DL | 1 |
| Gold, PW | 1 |
| Wehr, T | 1 |
| Rebar, R | 1 |
| Garfinkel, PE | 2 |
| Stancer, HC | 2 |
| Mandell, AJ | 2 |
| Knapp, S | 1 |
| Vestergaard, P | 1 |
| Sørensen, T | 1 |
| Hoppe, E | 1 |
| Rafaelsen, OJ | 1 |
| Yates, CM | 1 |
| Nicolaou, N | 1 |
| Godse, DD | 1 |
| Amamoto, T | 1 |
| Sarai, K | 1 |
| Ban, TA | 1 |
| Fyrö, B | 1 |
| Petterson, U | 1 |
| Sedvall, G | 1 |
| Mendels, J | 3 |
| Subrahmanyam, S | 1 |
| Fink, E | 1 |
| Carpenter, WT | 1 |
| Gordon, EK | 3 |
| Nisijima, K | 1 |
| Ishiguro, T | 1 |
| Secunda, SK | 3 |
| Croughan, J | 1 |
| Lewine, RR | 1 |
| Risch, SC | 1 |
| Risby, E | 1 |
| Stipetic, M | 1 |
| Jewart, RD | 1 |
| Eccard, M | 1 |
| Caudle, J | 1 |
| Pollard, W | 1 |
| Roy, A | 3 |
| Dejong, J | 1 |
| Ferraro, T | 1 |
| Sarrias, MJ | 2 |
| Martínez, E | 2 |
| Celada, P | 1 |
| Udina, C | 2 |
| Alvarez, E | 2 |
| Artigas, F | 2 |
| Pickar, D | 1 |
| Doran, AR | 1 |
| Ninan, P | 1 |
| Paul, SM | 1 |
| Golden, RN | 1 |
| Calil, HM | 1 |
| Ross, RJ | 1 |
| Modai, I | 1 |
| Beigel, Y | 1 |
| Cygielman, G | 1 |
| López-Ibor, JJ | 1 |
| Saiz-Ruiz, J | 1 |
| Pérez de los Cobos, JC | 1 |
| Hoffmann, G | 3 |
| Linkowski, P | 1 |
| Kerkhofs, M | 1 |
| Desmedt, D | 1 |
| Mendlewicz, J | 1 |
| Redmond, DE | 1 |
| Swann, A | 1 |
| Casper, R | 1 |
| Vale, AL | 1 |
| Ratcliffe, F | 1 |
| Brown, GL | 1 |
| Cross, CK | 1 |
| Koslow, S | 1 |
| Kocsis, JH | 1 |
| Stanley, M | 1 |
| Stanley, B | 1 |
| Matthews, B | 1 |
| Brown, L | 1 |
| Csernansky, JG | 1 |
| Pfefferbaum, A | 1 |
| Tandon, R | 1 |
| Channabasavanna, SM | 1 |
| Greden, JF | 1 |
| Kontaxakis, V | 1 |
| Markidis, M | 1 |
| De Jong, J | 1 |
| Gelpí, E | 1 |
| Berrettini, WH | 1 |
| Nurnberger, JI | 1 |
| Seppala, T | 1 |
| Narrow, W | 1 |
| Simmons-Alling, S | 1 |
| Gershon, ES | 1 |
| Riederer, P | 1 |
| Beckmann, H | 3 |
| Brücke, T | 1 |
| Ashcroft, GW | 3 |
| Blackburn, IM | 1 |
| Eccleston, D | 3 |
| Glen, AI | 1 |
| Hartley, W | 1 |
| Kinloch, NE | 1 |
| Lonergan, M | 1 |
| Murray, LG | 1 |
| Pullar, IA | 2 |
| Crawford, TB | 2 |
| Sharman, DF | 1 |
| MacDougall, EJ | 1 |
| Stanton, JB | 1 |
| Binns, JK | 1 |
| Sjöström, R | 5 |
| Murphy, DL | 1 |
| House, KM | 1 |
| Dunner, DL | 1 |
| Himwich, WA | 1 |
| Fukuyama, GS | 1 |
| Schildkraut, JJ | 1 |
| Ackenheil, M | 2 |
| Markianos, E | 2 |
| Nyström, I | 1 |
| Raese, J | 2 |
| Wilk, S | 1 |
| Shopsin, B | 1 |
| Gershon, S | 1 |
| Suhl, M | 1 |
| Matussek, N | 1 |
| Sack, RL | 2 |
| Roos, BE | 3 |
| Cundall, RL | 1 |
| Davidson, DL | 1 |
| Dobson, J | 1 |
| Dow, RC | 1 |
| Loose, RW | 1 |
| Pandey, GN | 1 |
| Wittenborn, JR | 1 |
| Greil, W | 1 |
| Haskovec, L | 1 |
| Rysánek, K | 1 |
| Coppen, A | 1 |
| Court, JH | 1 |
| Fitzgerald, RG | 1 |
| Ramsey, TA | 1 |
| Stokes, JW | 1 |
| Bojanovsky, J | 1 |
| Slowik, S | 1 |
| Gerbode, FA | 1 |
| Nagao, Y | 1 |
| Tsuchiya, K | 1 |
| Takamizawa, M | 1 |
| Kobayashi, T | 1 |
| Toru, M | 1 |
| Kobayashi, K | 1 |
| Kariya, T | 1 |
| Constantinidis, J | 1 |
| Dejaiffe, G | 1 |
| Cazzullo, CL | 1 |
| Mangoni, A | 1 |
| Mascherpa, G | 1 |
| Dencker, SJ | 1 |
| Malm, U | 1 |
| Werdinius, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase I Randomized, Double-blinded, Placebo-controlled Dose Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetic of HS-10353 in Chinese Adult Subjects[NCT05195203] | Phase 1 | 96 participants (Actual) | Interventional | 2021-01-27 | Completed | ||
| [NCT00004325] | 200 participants | Observational | 1988-12-31 | Completed | |||
| Imaging Framework for Testing GABAergic/Glutamatergic Drugs in Bipolar Alcoholics[NCT03220776] | Phase 2 | 54 participants (Actual) | Interventional | 2017-08-07 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Concentrations of GABA+, referenced to unsuppressed water and corrected for within-voxel CSF proportion, in dorsal anterior cingulate cortex measured via Proton Magnetic Resonance Spectroscopy (i.e., MEGA-PRESS). (NCT03220776)
Timeframe: Day 5 of each experimental condition
| Intervention | mmol/kg (Mean) |
|---|---|
| N-Acetylcysteine | 3.90 |
| Gabapentin | 3.93 |
| Placebo Oral Tablet | 3.73 |
Concentrations of Glx (i.e., glutamate + glutamine), referenced to unsuppressed water and corrected for within-voxel CSF proportion, in dorsal anterior cingulate cortex measured via Proton Magnetic Resonance Spectroscopy. (NCT03220776)
Timeframe: Day 5 of each experimental condition
| Intervention | mmol/kg (Mean) |
|---|---|
| N-Acetylcysteine | 21.59 |
| Gabapentin | 21.69 |
| Placebo Oral Tablet | 22.25 |
17 reviews available for hydroxyindoleacetic acid and Bipolar Disorder
| Article | Year |
|---|---|
Biomarkers in cerebrospinal fluid of patients with bipolar disorder versus healthy individuals: A systematic review.
Topics: Biomarkers; Bipolar Disorder; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid | 2018 |
Suicidality in pediatric bipolar disorder.
Topics: Age of Onset; Bipolar Disorder; Child; Demography; Family; Humans; Hydroxyindoleacetic Acid; Intenti | 2009 |
Acute tryptophan depletion. Part II: clinical effects and implications.
Topics: Alleles; Alzheimer Disease; Autistic Disorder; Bipolar Disorder; Cognitive Behavioral Therapy; Depre | 2005 |
Bipolar disorder and suicide: research synthesis and clinical translation.
Topics: Antidepressive Agents; Antimanic Agents; Biomarkers; Bipolar Disorder; Cause of Death; Clinical Tria | 2008 |
Reassessing the bipolar-unipolar dichotomy.
Topics: Bipolar Disorder; Catechol O-Methyltransferase; Depressive Disorder; Diagnosis, Differential; Female | 1980 |
Approaches to neuropeptide and, in particular, endorphin measurements.
Topics: Bipolar Disorder; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Depressive Dis | 1984 |
Genetic factors in depression and suicide.
Topics: Adoption; Bipolar Disorder; Depressive Disorder; Diseases in Twins; Electroencephalography; Family; | 1984 |
The switch process in manic-depressive psychosis.
Topics: Amphetamines; Animals; Bipolar Disorder; Calcium; Cyclic AMP; Cyclic GMP; Electroencephalography; Ho | 1977 |
[Amines in mental disorders (author's transl)].
Topics: Aggression; Biogenic Amines; Bipolar Disorder; Brain; Catecholamines; Dopamine; Emotions; Humans; Hy | 1977 |
Biogenic amine hypotheses of affective disorders.
Topics: Affective Symptoms; Antidepressive Agents; Antidepressive Agents, Tricyclic; Biogenic Amines; Bipola | 1979 |
Studies of amine metabolites in affective illness and in schizophrenia: a comparative analysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Antidepressive Agents, Tricyclic; Bipolar Disorder; Brain; Depressio | 1975 |
Pharmacotherapy of depression--a critical review.
Topics: Adjustment Disorders; Antidepressive Agents, Tricyclic; Bipolar Disorder; Brain; Depression; Dopamin | 1975 |
Simulated behavior states: an approach to specificity in psychobiological research.
Topics: Biology; Bipolar Disorder; Cyclic AMP; Depression; Emotions; Homovanillic Acid; Humans; Hydroxyindol | 1973 |
Biogenic amines and affective disorders.
Topics: Affective Symptoms; Biogenic Amines; Bipolar Disorder; Blood Platelets; Brain; Catechol O-Methyltran | 1974 |
[Biochemistry of depression].
Topics: Animals; Bipolar Disorder; Brain; Central Nervous System; Depression; Dihydroxyphenylalanine; Glycol | 1972 |
[Monoamines and manic-depressive syndromes].
Topics: Amines; Animals; Bipolar Disorder; Brain Chemistry; Cats; Dogs; Epinephrine; Humans; Hydroxyindoleac | 1967 |
Electrolytes and mental illness.
Topics: Affective Symptoms; Animals; Biological Transport; Bipolar Disorder; Calcium; Cell Membrane Permeabi | 1969 |
12 trials available for hydroxyindoleacetic acid and Bipolar Disorder
| Article | Year |
|---|---|
Effect of low-dose clorgyline on 24-hour urinary monoamine excretion in patients with rapidly cycling bipolar affective disorder.
Topics: Bipolar Disorder; Circadian Rhythm; Clorgyline; Dopamine; Dose-Response Relationship, Drug; Epinephr | 1982 |
Drug-induced actions on brain neurotransmitter systems and changes in the behaviors and emotions of depressed patients.
Topics: Amitriptyline; Behavior; Bipolar Disorder; Brain Chemistry; Depressive Disorder; Double-Blind Method | 1994 |
Imipramine and desipramine in plasma and spinal fluid: relationship to clinical response and serotonin metabolism.
Topics: Adult; Bipolar Disorder; Brain; Clinical Trials as Topic; Depression; Desipramine; Double-Blind Meth | 1978 |
The effect of lithium treatment on manic symptoms and levels of monoamine metabolites in cerebrospinal fluid of manic depressive patients.
Topics: Adolescent; Adult; Aged; Bipolar Disorder; Clinical Trials as Topic; Female; Homovanillic Acid; Huma | 1975 |
Stress, depression, and mania: relationship between perceived role of stressful events and clinical and biochemical characteristics.
Topics: Adaptation, Psychological; Adult; Amitriptyline; Arousal; Bipolar Disorder; Catecholamines; Depressi | 1990 |
Selective antidepressants and cerebrospinal fluid. Lack of specificity on norepinephrine and serotonin metabolites.
Topics: Adolescent; Adult; Aged; Bipolar Disorder; Clorgyline; Depressive Disorder; Desipramine; Female; Gly | 1985 |
Estimation of brain amine metabolism in affective illness: cerebrospinal fluid studies utilizing probenecid.
Topics: Bipolar Disorder; Brain; Depression; Dihydroxyphenylalanine; Fenclonine; Homovanillic Acid; Humans; | 1974 |
The "switch process" in manic-depressive illness. II. Relationship to catecholamines, REM sleep, and drugs.
Topics: Affective Symptoms; Antidepressive Agents; Bipolar Disorder; Catecholamines; Catechols; Dihydroxyphe | 1972 |
5-Hydroxyindole acetic acid and homovanillic acid in cerebrospinal fluid in manic-depressive psychosis and the effect of probenecid treatment.
Topics: Adult; Age Factors; Aged; Bipolar Disorder; Body Weight; Clinical Trials as Topic; Female; Half-Life | 1973 |
Inhibition of dopamine-b-hydroxylase in manic patients. A clinical trial and fusaric acid.
Topics: Bipolar Disorder; Clinical Trials as Topic; Dopamine; Dopamine beta-Hydroxylase; Enzyme Inhibitors; | 1974 |
Behavioral effects of a new dopamine-beta-hydroxylase inhibitor (fusaric acid) in man.
Topics: Administration, Oral; Bipolar Disorder; Clinical Trials as Topic; Depression; Dopamine beta-Hydroxyl | 1974 |
The action of reserpine in imipramine-resistant depressive patients. Clinical and biochemical study.
Topics: Adult; Bipolar Disorder; Blood Pressure; Body Temperature; Clinical Trials as Topic; Depression; Dru | 1967 |
114 other studies available for hydroxyindoleacetic acid and Bipolar Disorder
| Article | Year |
|---|---|
Tryptophan and Kynurenine Metabolites: Are They Related to Depression?
Topics: Adult; Bipolar Disorder; Case-Control Studies; Depressive Disorder, Major; Female; Humans; Hydroxyin | 2019 |
Anxiety in major depression and cerebrospinal fluid free gamma-aminobutyric acid.
Topics: Adult; Age Factors; Anxiety; Bipolar Disorder; Case-Control Studies; Chromatography, High Pressure L | 2014 |
Kynurenine pathway and white matter microstructure in bipolar disorder.
Topics: Adult; Bipolar Disorder; Diffusion Tensor Imaging; Female; Humans; Hydroxyindoleacetic Acid; Kynuren | 2018 |
Increased risk of suicide attempt in mood disorders and TPH1 genotype.
Topics: Adolescent; Adult; Aged; Bipolar Disorder; Black or African American; Depressive Disorder, Major; Fe | 2009 |
CSF 5-HIAA and DST non-suppression--orthogonal biologic risk factors for suicide in male mood disorder inpatients.
Topics: Adult; Biomarkers; Bipolar Disorder; Cause of Death; Cohort Studies; Cross-Sectional Studies; Depres | 2009 |
Lower CSF HVA and 5-HIAA in bipolar disorder type 1 with a history of childhood ADHD.
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Female; Follow-Up Studies; H | 2009 |
Cholesterol and CSF 5-HIAA in attempted suicide.
Topics: Adjustment Disorders; Adolescent; Adult; Age Factors; Aged; Alcoholism; Anxiety Disorders; Bipolar D | 2010 |
[Urinary excretion of 5-hydroxyindolacetic acid (5-HIAA) in 150 patients with depressive syndrome and maniacal agitation. (Its modifications by 5-hydroxy-tryptophan loading and therapy in the depressive states)].
Topics: Bipolar Disorder; Depression; Depressive Disorder; Humans; Hydroxyindoleacetic Acid; Indoleacetic Ac | 1963 |
[SEROTONIN AND PSYCHIATRY].
Topics: Bipolar Disorder; Catecholamines; Drug Therapy; Hallucinations; Hallucinogens; Humans; Hydroxyindole | 1964 |
A prospective study of the association of cerebrospinal fluid monoamine metabolite levels with lethality of suicide attempts in patients with bipolar disorder.
Topics: Adult; Bipolar Disorder; Demography; Female; Follow-Up Studies; Homovanillic Acid; Humans; Hydroxyin | 2006 |
No association between a TPH2 promoter polymorphism and mood disorders or monoamine turnover.
Topics: Adult; Bipolar Disorder; Child; Child Abuse; Depressive Disorder, Major; Female; Genotype; Homovanil | 2008 |
[Tryptaminuria and urinary 5-H.I.A.A. in neuropsychiatry (preliminary note)].
Topics: Bipolar Disorder; Depression; Humans; Hydroxyindoleacetic Acid; Monoamine Oxidase Inhibitors; Neurot | 1967 |
Dopamine and mania: behavioral and biochemical effects of the dopamine receptor blocker pimozide.
Topics: Adult; Behavior; Bipolar Disorder; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic | 1980 |
CSF monoamine metabolites in child and adult psychiatric patients. A developmental perspective.
Topics: Adolescent; Adult; Age Factors; Aged; Autistic Disorder; Bipolar Disorder; Child; Child, Preschool; | 1980 |
Monoamine metabolites in cerebrospinal fluid of depressive subgroups.
Topics: Adult; Alcoholism; Bipolar Disorder; Depressive Disorder; Female; Glycols; Homovanillic Acid; Humans | 1980 |
[Current biochemical conceptions of mental diseases. II. Role of changes in the biogenic amine system in the pathogenesis of affective disorders].
Topics: 3-Methoxy-4-hydroxyphenylethanol; Affective Disorders, Psychotic; Antidepressive Agents, Tricyclic; | 1980 |
[Emotional stress and biochemical responses of completely recovered manic depressive patients (author's transl)].
Topics: Adolescent; Adult; Bipolar Disorder; Blood Pressure; Epinephrine; Female; Humans; Hydroxyindoleaceti | 1981 |
Neuroendocrine and neurochemical measurements in depression.
Topics: Adult; Aged; Bipolar Disorder; Depressive Disorder; Dexamethasone; Glycols; Homovanillic Acid; Human | 1981 |
Symptom patterns in unipolar and bipolar depression correlating with monoamine metabolites in the cerebrospinal fluid: I. General patterns.
Topics: Adult; Aged; Bipolar Disorder; Depressive Disorder; Female; Glycols; Homovanillic Acid; Humans; Hydr | 1980 |
Symptom patterns in unipolar and bipolar depression correlating with monoamine metabolites in the cerebrospinal fluid: II. Suicide.
Topics: Adult; Aged; Anger; Bipolar Disorder; Depressive Disorder; Female; Glycols; Humans; Hydroxyindoleace | 1980 |
Recent advances in psychopharmacology of depression.
Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depressive Disorder; Dexa | 1981 |
Biological relationships between mania and melancholia.
Topics: Affective Disorders, Psychotic; Antidepressive Agents, Tricyclic; Bipolar Disorder; Carbamazepine; D | 1982 |
Early morning awakening in unipolar depressives with higher levels of platelet MAO activity.
Topics: Adolescent; Adult; Aged; Bipolar Disorder; Blood Platelets; Depressive Disorder; Female; Homovanilli | 1982 |
CSF cortisol in patients with depression, mania, or anorexia nervosa and in normal subjects.
Topics: Adult; Affective Disorders, Psychotic; Anorexia Nervosa; Bipolar Disorder; Depressive Disorder; Fema | 1983 |
Patterns of depression reflected in pituitary - thyroid and pituitary - adrenal endocrine changes.
Topics: Adolescent; Adult; Aged; Bipolar Disorder; Depressive Disorder; Dexamethasone; Homovanillic Acid; Hu | 1982 |
CSF monoamine metabolites in mania.
Topics: Adult; Affective Disorders, Psychotic; Aged; Bipolar Disorder; Female; Glycols; Homovanillic Acid; H | 1983 |
Acid metabolites and precursor amino acids of 5-hydroxytryptamine and dopamine in affective and other psychiatric disorders.
Topics: Adjustment Disorders; Adult; Aged; Amino Acids; Bipolar Disorder; Depressive Disorder; Dopamine; Fem | 1983 |
Relationship between cerebrospinal fluid amine metabolites, neuroendocrine findings and personality dimensions (Marke-Nyman scale factors) in psychiatric patients.
Topics: Alcoholism; Bipolar Disorder; Depressive Disorder; Dexamethasone; Female; Homovanillic Acid; Humans; | 1983 |
The effect of dexamethasone on cerebrospinal fluid monoamine metabolites and cortisol in psychiatric patients.
Topics: Adult; Aged; Alcoholism; Bipolar Disorder; Depressive Disorder; Dexamethasone; Female; Homovanillic | 1983 |
CSF and urinary biogenic amines and metabolites in depression and mania. A controlled, univariate analysis.
Topics: Adult; Affective Disorders, Psychotic; Biogenic Amines; Bipolar Disorder; Depressive Disorder; Epine | 1983 |
Cerebrospinal fluid biochemical examinations: do they reflect clinical or biological differences?
Topics: Adult; Aged; Alcoholism; Bipolar Disorder; Calcium; Depressive Disorder; Dexamethasone; Female; Homo | 1983 |
CSF 5HIAA and personal and family history of suicide in affectively ill patients: a negative study.
Topics: Adult; Aged; Bipolar Disorder; Depressive Disorder; Female; Humans; Hydroxyindoleacetic Acid; Male; | 1983 |
CSF monoamine metabolites in melancholia.
Topics: Adult; Age Factors; Aged; Bipolar Disorder; Depressive Disorder; Female; Glycols; Homovanillic Acid; | 1984 |
Some clinical and biochemical predictors of outcome in depression.
Topics: Adult; Aged; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Female; Homovanillic Acid | 1984 |
Pain as a symptom in depressive disorders and its relationship to platelet monoamine oxidase activity.
Topics: Adult; Bipolar Disorder; Blood Platelets; Depressive Disorder; Female; Humans; Hydroxyindoleacetic A | 1984 |
Pretreatment neurotransmitter metabolite levels and response to tricyclic antidepressant drugs.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depressive Disorder; Female; Homo | 1984 |
CSF neurochemistry in depressed, manic, and schizophrenic patients compared with that of normal controls.
Topics: Adolescent; Adult; Age Factors; Aged; Bipolar Disorder; Calcium; Choline; Depressive Disorder; Femal | 1984 |
Reduced brain 5-HT and elevated NE turnover and metabolites in bipolar affective disorder.
Topics: Adult; Bipolar Disorder; Brain Chemistry; Brain Mapping; Dopamine; Female; Homovanillic Acid; Humans | 1994 |
CSF 5-HIAA predicts suicide risk after attempted suicide.
Topics: Adult; Aged; Anxiety Disorders; Bipolar Disorder; Cause of Death; Depressive Disorder; Female; Follo | 1994 |
Effects of monoamine oxidase A inhibition on plasma biogenic amine metabolites in depressed patients.
Topics: Adult; Arousal; Benzamides; Biogenic Amines; Bipolar Disorder; Chromatography, High Pressure Liquid; | 1994 |
Biogenic amines in seasonal affective disorder: effects of light therapy.
Topics: Adult; Bipolar Disorder; Depressive Disorder; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic | 1993 |
Decreased serotonin transporter binding in unaffected relatives of manic depressive patients.
Topics: Adrenergic Uptake Inhibitors; Adult; Biomarkers; Bipolar Disorder; Blood Platelets; Carrier Proteins | 1999 |
Suicide in teenagers: assessment, management, and prevention.
Topics: Adolescent; Adolescent Behavior; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Femal | 2001 |
[Clinical and biochemical contributions on the action of maprotiline and clomipramine in depressive states (preliminary observation)].
Topics: Adult; Bipolar Disorder; Clomipramine; Depression; Female; Humans; Hydroxyindoleacetic Acid; Male; M | 1979 |
[The role of serotonin in affective disorders (author's transl)].
Topics: Antidepressive Agents, Tricyclic; Bipolar Disorder; Brain; Depression; Humans; Hydroxyindoleacetic A | 1979 |
Central serotonin metabolism and frequency of depression.
Topics: Adult; Bipolar Disorder; Brain; Depressive Disorder; Female; Humans; Hydroxyindoleacetic Acid; Male; | 1979 |
Interactions between central monoaminergic systems: dopamine-serotonin.
Topics: Adolescent; Adult; Aged; Bipolar Disorder; Depression; Dopamine; Dyskinesia, Drug-Induced; Female; H | 1979 |
[Biochemistry of depression].
Topics: Adrenocorticotropic Hormone; Bipolar Disorder; Contraceptives, Oral; Cyclic AMP; Depression; Dopamin | 1976 |
Biological and behavioral effects of one night's sleep deprivation in depressed patients and normals.
Topics: Adult; Aged; Bipolar Disorder; Body Temperature; Calcium; Circadian Rhythm; Depression; Electroencep | 1979 |
The Harold E. Himwich Memorial Lecture. Significance of biochemical parameters in the diagnosis, treatment, and prevention of depressive disorders.
Topics: 5-Hydroxytryptophan; Antidepressive Agents, Tricyclic; Autopsy; Bipolar Disorder; Brain Chemistry; C | 1977 |
Pituitary thyrotropin response to thyrotropin-releasing hormone in affective illness: relationship to spinal fluid amine metabolites.
Topics: Age Factors; Bipolar Disorder; Depression; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Ac | 1977 |
Depression: new evidence in support of biological differentiation.
Topics: Adult; Bipolar Disorder; Carbidopa; Depression; Female; Humans; Hydroxyindoleacetic Acid; Male; Meth | 1979 |
Asymmetry and mood, emergent properties of serotonin regulation.
Topics: Affect; Amphetamine; Animals; Bipolar Disorder; Brain; Calcium; Cocaine; Dominance, Cerebral; Humans | 1979 |
On a mechanism for the mood and personality changes of adult and later life. A psychobiological hypothesis.
Topics: Affect; Aging; Animals; Antidepressive Agents, Tricyclic; Bipolar Disorder; Brain; Clomipramine; Dom | 1979 |
Lithium: clinical effects and cerebrospinal fluid acid monoamine metabolites.
Topics: Adult; Affective Symptoms; Aged; Biogenic Amines; Bipolar Disorder; Depression; Electroencephalograp | 1977 |
Biogenic amine metabolites in cerebrospinal fluid of patients with affective disorders.
Topics: Adult; Aged; Biogenic Amines; Bipolar Disorder; Depression; Female; Homovanillic Acid; Humans; Hydro | 1978 |
CNS monoamine metabolism in bipolar affective disorder. Evaluation using a peripheral decarboxylase inhibitor.
Topics: Adolescent; Adult; Amines; Bipolar Disorder; Brain; Carbidopa; Catecholamines; Female; Humans; Hydro | 1977 |
A dopaminergic mechanism in mania.
Topics: Bipolar Disorder; Depression; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Lithium | 1976 |
CSF acid monoamine metabolities as a possible reflection of central MAO activity in chronic schizophrenia.
Topics: Acute Disease; Adolescent; Adult; Bipolar Disorder; Chronic Disease; Female; Homovanillic Acid; Huma | 1976 |
On the tryptophan-serotonin metabolism in manic-depressive disorders. Changes in plasma 5-HT and 5-HIAA levels and urinary 5-HIAA excretion following oral loading of L-5HTP in patients with depression.
Topics: 5-Hydroxytryptophan; Administration, Oral; Adult; Bipolar Disorder; Female; Humans; Hydroxyindoleace | 1976 |
Reduced central serotonergic activity in mania: implications for the relationship between depression and mania.
Topics: Bipolar Disorder; Brain; Depression; Disease Models, Animal; Humans; Hydroxyindoleacetic Acid; Hypno | 1975 |
Role of biogenic amines in certain pathological conditions.
Topics: Acute Disease; Adult; Aggression; Biogenic Amines; Bipolar Disorder; Chlorpromazine; Chronic Disease | 1975 |
Cerebrospinal fluid amine metabolites in acute schizophrenia.
Topics: Acute Disease; Adolescent; Adult; Amines; Bipolar Disorder; Dopamine; Homovanillic Acid; Humans; Hyd | 1975 |
Central noradrenergic function in man: vanillylmandelic acid in CSF.
Topics: Acute Disease; Affective Symptoms; Bipolar Disorder; Depression; Homovanillic Acid; Humans; Hydroxyi | 1975 |
Neuroleptic malignant syndrome: a study of CSF monoamine metabolism.
Topics: Adult; Biogenic Monoamines; Bipolar Disorder; Depressive Disorder; Female; Homovanillic Acid; Humans | 1990 |
Lateral ventricle-brain ratio and balance between CSF HVA and 5-HIAA in schizophrenia.
Topics: Adult; Age Factors; Bipolar Disorder; Body Height; Body Weight; Brain; Brain Chemistry; Cerebral Ven | 1991 |
CSF GABA in depressed patients and normal controls.
Topics: Adult; Bipolar Disorder; Depressive Disorder; Female; gamma-Aminobutyric Acid; Homovanillic Acid; Hu | 1991 |
Plasma free 5HT and platelet 5HT in depression: case-control studies and the effect of antidepressant therapy.
Topics: Antidepressive Agents; Bipolar Disorder; Blood Platelets; Case-Control Studies; Depression; Female; | 1991 |
Hallucinations in patients with major depression. Interactions between CSF monoaminergic and endorphinergic indices.
Topics: Adult; Age Factors; Bipolar Disorder; Depressive Disorder; Endorphins; Female; Hallucinations; Homov | 1985 |
Cerebrospinal fluid monoamine and monoamine metabolite concentrations in melancholia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Bipolar Disorder; Depressive Disorder; Dopamine; Female | 1985 |
Urinary amine metabolite excretion in a patient with adrenergic hyperactivity state: reaction to phenelzine withdrawal and combined treatment.
Topics: Bipolar Disorder; Delirium; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Meta | 1986 |
Biological correlations of suicide and aggressivity in major depressions (with melancholia): 5-hydroxyindoleacetic acid and cortisol in cerebral spinal fluid, dexamethasone suppression test and therapeutic response to 5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Adult; Aggression; Bipolar Disorder; Carbidopa; Depressive Disorder; Dexamethas | 1985 |
Effects of ECT on sleep and CSF biogenic amines in affective illness.
Topics: Adult; Biogenic Amines; Bipolar Disorder; Depressive Disorder; Electroconvulsive Therapy; Homovanill | 1985 |
Cerebrospinal fluid amine metabolites. Relationships with behavioral measurements in depressed, manic, and healthy control subjects.
Topics: Bipolar Disorder; Depressive Disorder; Female; Glycols; Homovanillic Acid; Hospitalization; Humans; | 1986 |
Effect of lithium administration on rat brain 5-hydroxyindole levels in a possible animal model for mania.
Topics: Animals; Bipolar Disorder; Brain; Chlordiazepoxide; Disease Models, Animal; Female; Hydroxyindoleace | 1987 |
Cerebrospinal fluid correlates of suicide attempts and aggression.
Topics: Aggression; Animals; Bipolar Disorder; Depressive Disorder; Homovanillic Acid; Humans; Hydroxyindole | 1986 |
Studies of amine metabolites in depressed patients. Relationship to suicidal behavior.
Topics: Bipolar Disorder; Brain; Depressive Disorder; Epinephrine; Homovanillic Acid; Humans; Hydrocortisone | 1986 |
Lithium carbonate treatment of mania. Cerebrospinal fluid and urinary monoamine metabolites and treatment outcome.
Topics: Adult; Aged; Bipolar Disorder; Brain; Dopamine; Epinephrine; Female; Homovanillic Acid; Humans; Hydr | 1987 |
N-acetylation and serotonergic measures in a group of psychiatric patients.
Topics: Acetylation; Adult; Bipolar Disorder; Depressive Disorder; Female; Humans; Hydroxyindoleacetic Acid; | 1988 |
Seasonal changes of CSF monoamine metabolites in psychiatric patients: what is the source?
Topics: Bipolar Disorder; Depressive Disorder; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Mental D | 1988 |
CSF biochemical correlates of mixed affective states.
Topics: Adult; Bipolar Disorder; Calcium; Depressive Disorder; Electrolytes; Female; Homovanillic Acid; Huma | 1988 |
Clonidine in the treatment of mixed bipolar disorder.
Topics: Adult; Bipolar Disorder; Clonidine; Dexamethasone; Dopamine beta-Hydroxylase; Female; Homovanillic A | 1989 |
Cerebrospinal fluid monoamine metabolites and suicidal behavior in depressed patients. A 5-year follow-up study.
Topics: Adult; Bipolar Disorder; Depressive Disorder; Dopamine; Female; Follow-Up Studies; Homovanillic Acid | 1989 |
Increased plasma free serotonin but unchanged platelet serotonin in bipolar patients treated chronically with lithium.
Topics: Adult; Bipolar Disorder; Blood Platelets; Chromatography, High Pressure Liquid; Female; Humans; Hydr | 1989 |
Effects of amitriptyline and imipramine on brain amine neurotransmitter metabolites in cerebrospinal fluid.
Topics: Adult; Amitriptyline; Bipolar Disorder; Depressive Disorder; Dopamine; Double-Blind Method; Female; | 1985 |
Cerebrospinal fluid and plasma monoamines and their metabolites in euthymic bipolar patients.
Topics: 3,4-Dihydroxyphenylacetic Acid; Bipolar Disorder; Dopamine; Homovanillic Acid; Humans; Hydroxyindole | 1985 |
[Current biochemical hypotheses of endogenous depression].
Topics: 5-Hydroxytryptophan; Amitriptyline; Autopsy; Biogenic Amines; Bipolar Disorder; Brain; Depressive Di | 1985 |
Modified amine hypothesis for the aetiology of affective illness.
Topics: Affective Symptoms; Amines; Animals; Antidepressive Agents; Binding Sites; Biogenic Amines; Bipolar | 1972 |
Changes on recovery in the concentrations of tryptophan and the biogenic amine metabolites in the cerebrospinal fluid of patients with affective illness.
Topics: Adult; Affective Symptoms; Antipsychotic Agents; Biogenic Amines; Bipolar Disorder; Butyrophenones; | 1973 |
5-hydroxyindole compounds in the cerebrospinal fluid of patients with psychiatric or neurological diseases.
Topics: Alcoholism; Bipolar Disorder; Central Nervous System Diseases; Humans; Hydroxyindoleacetic Acid; Imi | 1966 |
Steady-state levels of probenecid and their relation to acid monoamine metabolites in human cerebrospinal fluid.
Topics: Adult; Aged; Benzoates; Bipolar Disorder; Blood-Brain Barrier; Female; Humans; Huntington Disease; H | 1972 |
Absence of effect of para-chlorophenylalanine on 5-hydroxyindoleacetic acid in cerebrospinal fluid in man.
Topics: Adult; Aged; Bipolar Disorder; Drug Interactions; Female; Fenclonine; Humans; Hydroxyindoleacetic Ac | 1972 |
Cerebrospinal fluid amine metabolites in affective illness: the probenecid technique.
Topics: Affective Symptoms; Biological Transport, Active; Bipolar Disorder; Brain; Brain Chemistry; Depressi | 1973 |
Genral neurophysiology (biochemical aspects).
Topics: Age Factors; Animals; Bipolar Disorder; Blood-Brain Barrier; Brain; Brain Diseases; Cerebrovascular | 1971 |
[Effect of clozapine on the excretion of 3-methoxy-4-hydroxy-phenylglycol, homovanillic acid and 5-hydroxy-indole acetic acid in urine and cerebrospinal fluid].
Topics: Azepines; Bipolar Disorder; Dopamine beta-Hydroxylase; Glycols; Homovanillic Acid; Humans; Hydroxyin | 1974 |
Fluorometric measurement of 5-hydroxyindoleacetic acid (5HIAA) and tryptophan in human CSF: effects of high doses of probenecid.
Topics: Administration, Oral; Adolescent; Adult; Bipolar Disorder; Brain Chemistry; Depression; Female; Fluo | 1974 |
Cerebrospinal fluid levels of MHPG in affective disorders.
Topics: Adjustment Disorders; Affective Symptoms; Bipolar Disorder; Carbonates; Catechols; Depression; Glyco | 1972 |
5-Hydroxyindolacetic acid and homovanillic acid in cerebrospinal fluid in manic-depressive psychosis.
Topics: Adult; Aged; Antidepressive Agents; Bipolar Disorder; Butyrophenones; Female; Humans; Hydroxyindolea | 1972 |
5-Hydroxytryptamine metabolism in affective illness: the effect of tryptophan administration.
Topics: Adult; Affective Symptoms; Age Factors; Aged; Bipolar Disorder; Depression; Female; Humans; Hydroxyi | 1973 |
Metabolism of tryptophan in depressive disease.
Topics: Adult; Bipolar Disorder; Depression; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; Metabolic C | 1973 |
Lumbar CSF 5-hydroxyindoleacetic acid and homovanillic acid in affective syndromes.
Topics: Adult; Affective Symptoms; Amitriptyline; Animals; Bipolar Disorder; Brain Chemistry; Cats; Depressi | 1974 |
Deductive approaches to the catecholamine hypothesis of affective disorders.
Topics: Affective Symptoms; Antidepressive Agents; Biogenic Amines; Bipolar Disorder; Brain; Brain Chemistry | 1974 |
Antipsychotic efficacy of clozapine in correlation to changes in catecholamine metabolism in man.
Topics: Bipolar Disorder; Carbon Radioisotopes; Catecholamines; Chromatography, Gas; Dibenzazepines; Dopamin | 1974 |
Diagnosis of manic-depressive psychosis from cerebrospinal fluid concentration of 5-hydroxyindoleacetic acid.
Topics: Bipolar Disorder; Dose-Response Relationship, Drug; Half-Life; Homovanillic Acid; Humans; Hydroxyind | 1974 |
The continuum model as a resolution of paradoxed in manic-depressie psychosis.
Topics: Arousal; Behavior; Bipolar Disorder; Brain; Catecholamines; Epinephrine; Humans; Hydroxyindoleacetic | 1972 |
Biogenic amine metabolites in cerebrospinal fluid of depressed and manic patients.
Topics: Bipolar Disorder; Depression; Humans; Hydroxyindoleacetic Acid; Phenylacetates | 1972 |
[Biochemical correlates of a 48 hour periodic psychosis].
Topics: 17-Ketosteroids; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Bipolar Dis | 1971 |
[Clinical pharmacology (11): diagnostic methods].
Topics: Bipolar Disorder; Diagnostic Uses of Chemicals; Humans; Hydroxyindoleacetic Acid; Parkinson Disease; | 1970 |
[Excretion of 3-methoxy-4-hydroxy-amygdalic acid and 5-hydroxyindoleacetic acid in the urine of patients with depressive states].
Topics: Adult; Bipolar Disorder; Catecholamines; Depression; Female; Humans; Hydroxyindoleacetic Acid; Male; | 1968 |
Relationship of monoamine metabolites in human cerebrospinal fluid to age.
Topics: Adult; Age Factors; Bipolar Disorder; Brain; Depression; Female; Humans; Hydroxyindoleacetic Acid; M | 1968 |
Catecholamine metabolism of manic-depressive illness.
Topics: Antidepressive Agents; Bipolar Disorder; Calcium; Catecholamines; Creatinine; Disulfiram; Dopamine; | 1968 |
[Urinary excretion of 5-hydroxyindoleacetic acid (5-HIAA) in 20 atypical cycloid-type psychoses].
Topics: Adult; Bipolar Disorder; Female; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Schizophrenia; | 1965 |
Tryptophan metabolism in affective psychoses.
Topics: Adult; Amitriptyline; Antidepressive Agents; Bipolar Disorder; Female; Humans; Hydroxyindoleacetic A | 1966 |
Acid monoamine metabolites of cerebrospinal fluid in mental depression and mania.
Topics: Adult; Aged; Bipolar Disorder; Depression; Fluorometry; Humans; Hydroxyindoleacetic Acid; Male; Midd | 1966 |