hydroxyindoleacetic acid has been researched along with Benign Infantile Myoclonic Epilepsy in 11 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
| Excerpt | Relevance | Reference |
|---|---|---|
| " A patient with Lafora disease reported enough improvement in myoclonus-evoked convulsions to continue chronic use of the drug." | 2.68 | Neuropharmacology of progressive myoclonus epilepsy: response to 5-hydroxy-L-tryptophan. ( Ashwal, S; Bodensteiner, J; Franz, D; Haas, RH; Huang, Y; Pranzatelli, MR; Tate, E, 1995) |
| "Six of them showed initial decrease of seizure frequency and severity and maintained improvement in some neurodevelopmental skills." | 1.72 | Monoamine neurotransmitters in early epileptic encephalopathies: New insights into pathophysiology and therapy. ( Aparicio, J; Artuch, R; Cortès-Saladelafont, E; Cuadras, D; Fons, C; García-Cazorla, À; Horvath, G; Juliá-Palacios, N; Molina-Anguita, C; Sigatulina Bondarenko, M, 2022) |
| "The degenerative type of progressive myoclonus epilepsy (PME) is a hereditary disease with grand mal seizures, stimulus sensitive myoclonus, characteristic EEG and mental deterioration in the late stage." | 1.26 | Decrease of GABA in the cerebrospinal fluid of patients with progressive myoclonus epilepsy and its correlation with the decrease of 5HIAA and HVA. ( Airaksinen, EM; Leino, E, 1982) |
| "The neurochemical basis of myoclonus responding to 5HT precursors and clonazepam is discussed." | 1.26 | Clinical, biochemical, and physiological features distinguishing myoclonus responsive to 5-hydroxytryptophan, tryptophan with a monoamine oxidase inhibitor, and clonazepam. ( Chadwick, D; Hallett, M; Harris, R; Jenner, P; Marsden, CD; Reynolds, EH, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (72.73) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Juliá-Palacios, N | 1 |
| Molina-Anguita, C | 1 |
| Sigatulina Bondarenko, M | 1 |
| Cortès-Saladelafont, E | 1 |
| Aparicio, J | 1 |
| Cuadras, D | 1 |
| Horvath, G | 1 |
| Fons, C | 1 |
| Artuch, R | 1 |
| García-Cazorla, À | 1 |
| Koskiniemi, ML | 2 |
| Leino, E | 3 |
| MacDonald, E | 2 |
| Airaksinen, MM | 2 |
| Riekkinen, PJ | 2 |
| Salo, H | 1 |
| Airaksinen, EM | 1 |
| Pranzatelli, MR | 2 |
| Tate, E | 2 |
| Huang, Y | 1 |
| Haas, RH | 1 |
| Bodensteiner, J | 1 |
| Ashwal, S | 1 |
| Franz, D | 2 |
| Martens, JM | 1 |
| Chadwick, D | 1 |
| Hallett, M | 1 |
| Harris, R | 1 |
| Jenner, P | 1 |
| Reynolds, EH | 1 |
| Marsden, CD | 1 |
| Kimiya, S | 1 |
| Seki, T | 1 |
| Maezawa, M | 1 |
| Yamada, T | 1 |
| Tachibana, Y | 1 |
| Koskiniemi, M | 1 |
| Laakso, J | 1 |
| Kuurne, T | 1 |
| Laipio, M | 1 |
| Härkönen, M | 1 |
2 trials available for hydroxyindoleacetic acid and Benign Infantile Myoclonic Epilepsy
| Article | Year |
|---|---|
L-tryptophan-carbidopa trial in patients with long-standing progressive myoclonus epilepsy.
Topics: Blood Platelets; Carbidopa; Clinical Trials as Topic; Drug Therapy, Combination; Epilepsies, Myoclon | 1981 |
Neuropharmacology of progressive myoclonus epilepsy: response to 5-hydroxy-L-tryptophan.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Carbidopa; Cross-Over Studies; Double-Blind Method; Drug The | 1995 |
9 other studies available for hydroxyindoleacetic acid and Benign Infantile Myoclonic Epilepsy
| Article | Year |
|---|---|
Monoamine neurotransmitters in early epileptic encephalopathies: New insights into pathophysiology and therapy.
Topics: Child, Preschool; Electroencephalography; Epilepsies, Myoclonic; Epilepsy; Female; Humans; Hydroxyin | 2022 |
Deficient intestinal absorption of L-tryptophan in progressive myoclonus epilepsy without Lafora bodies.
Topics: Epilepsies, Myoclonic; Female; Humans; Hydroxyindoleacetic Acid; Indican; Intestinal Absorption; Kin | 1980 |
Homovanillic acid and 5-hydroxyindoleacetic acid levels in cerebrospinal fluid of patients with progressive myoclonus epilepsy.
Topics: Adult; Brain; Epilepsies, Myoclonic; Female; Finland; Homovanillic Acid; Humans; Hydroxyindoleacetic | 1980 |
Decrease of GABA in the cerebrospinal fluid of patients with progressive myoclonus epilepsy and its correlation with the decrease of 5HIAA and HVA.
Topics: Adult; Epilepsies, Myoclonic; Female; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Hydroxyind | 1982 |
Buspirone in progressive myoclonus epilepsy.
Topics: Adolescent; Adult; Brain; Buspirone; Epilepsies, Myoclonic; Female; Humans; Hydroxyindoleacetic Acid | 1993 |
Clinical, biochemical, and physiological features distinguishing myoclonus responsive to 5-hydroxytryptophan, tryptophan with a monoamine oxidase inhibitor, and clonazepam.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Benzodiazepinones; Carbidopa; Child, Preschool; Clonaz | 1977 |
Baltic myoclonus.
Topics: Adolescent; Brain; Child; Electroencephalography; Epilepsies, Myoclonic; Humans; Hydroxyindoleacetic | 1986 |
Analysis of monamine metabolism in cerebrospinal fluid in childhood epilepsies.
Topics: Adolescent; Brain Damage, Chronic; Child; Child, Preschool; Epilepsies, Myoclonic; Epilepsy; Epileps | 1989 |
Indole levels in human lumbar and ventricular cerebrospinal fluid and the effect of L-tryptophan administration.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Anticonvulsants; Child; Chromatography, High Pressure | 1985 |