Page last updated: 2024-10-21

hydroxyindoleacetic acid and Autotomy Human

hydroxyindoleacetic acid has been researched along with Autotomy Human in 11 studies

(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.

Research Excerpts

ExcerptRelevanceReference
"In a patient with the Lesch-Nyhan syndrome we found decreased spinal fluid 5-hydroxyindole acetic acid (5-HIAA), the major metabolite of serotonin, and decreased homovanillic acid (HVA), the major metabolite of dopamine, indicating a decrease in monoamine metabolism."7.66Effects of L-5-hydroxytryptophan on monoamine and amino acids turnover in the Lesch-Nyhan syndrome. ( Castells, S; Chakrabarti, C; Hurwic, M; Nyhan, WL; Perel, JM; Winsberg, BG, 1979)
"The effects of 5-hydroxytryptophan (5-HTP), a serotonin precursor, were studied in a boy with the Lesch-Nyhan syndrome."7.65The use of 5-hydroxytryptophan in a child with Lesch-Nyhan syndrome. ( Anders, TF; Barchas, JD; Berger, PA; Cann, HM; Ciaranello, RD, 1976)
"Rats were fed an artificial diet containing either their normal, or five times their normal, daily requirement of tryptophan for up to five weeks and were tested in an animal model of deafferentation pain, nerve lesion-induced autotomy."3.68The effect of tryptophan supplementation on autotomy induced by nerve lesions in rats. ( Abbott, FV; Young, SN, 1991)
"In a patient with the Lesch-Nyhan syndrome we found decreased spinal fluid 5-hydroxyindole acetic acid (5-HIAA), the major metabolite of serotonin, and decreased homovanillic acid (HVA), the major metabolite of dopamine, indicating a decrease in monoamine metabolism."3.66Effects of L-5-hydroxytryptophan on monoamine and amino acids turnover in the Lesch-Nyhan syndrome. ( Castells, S; Chakrabarti, C; Hurwic, M; Nyhan, WL; Perel, JM; Winsberg, BG, 1979)
"The effects of 5-hydroxytryptophan (5-HTP), a serotonin precursor, were studied in a boy with the Lesch-Nyhan syndrome."3.65The use of 5-hydroxytryptophan in a child with Lesch-Nyhan syndrome. ( Anders, TF; Barchas, JD; Berger, PA; Cann, HM; Ciaranello, RD, 1976)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19908 (72.73)18.7374
1990's3 (27.27)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Colado, MI1
Del Rio, J1
Peralta, E1
Castells, S1
Chakrabarti, C1
Winsberg, BG1
Hurwic, M1
Perel, JM1
Nyhan, WL1
Ciaranello, RD1
Anders, TF1
Barchas, JD1
Berger, PA1
Cann, HM1
Feria, M1
Abreu, P1
Abad, F1
Sánchez, A1
Abbott, FV1
Young, SN1
Crawley, JN1
Sutton, ME1
Pickar, D1
López-Ibor, JJ1
Saiz-Ruiz, J1
Pérez de los Cobos, JC1
Van Praag, HM1
Plutchik, R1
Conte, H1
Brown, GL1
Goodwin, FK1
Jankovic, J1
Caskey, TC1
Stout, JT1
Butler, IJ1
Mizuno, TI1
Yugari, Y1

Reviews

1 review available for hydroxyindoleacetic acid and Autotomy Human

ArticleYear
Animal models of self-destructive behavior and suicide.
    The Psychiatric clinics of North America, 1985, Volume: 8, Issue:2

    Topics: Altruism; Animals; Animals, Domestic; Animals, Laboratory; Animals, Wild; Animals, Zoo; Dexamethason

1985

Trials

1 trial available for hydroxyindoleacetic acid and Autotomy Human

ArticleYear
Letter: Self mutilation in Lesch-Nyhan syndrome.
    Lancet (London, England), 1974, Apr-20, Volume: 1, Issue:7860

    Topics: 5-Hydroxytryptophan; Administration, Oral; Child; Dihydroxyphenylalanine; Humans; Hydroxyindoleaceti

1974

Other Studies

9 other studies available for hydroxyindoleacetic acid and Autotomy Human

ArticleYear
Neonatal guanethidine sympathectomy suppresses autotomy and prevents changes in spinal and supraspinal monoamine levels induced by peripheral deafferentation in rats.
    Pain, 1994, Volume: 56, Issue:1

    Topics: Animals; Animals, Newborn; Biogenic Monoamines; Denervation; Guanethidine; Hydroxyindoleacetic Acid;

1994
Effects of L-5-hydroxytryptophan on monoamine and amino acids turnover in the Lesch-Nyhan syndrome.
    Journal of autism and developmental disorders, 1979, Volume: 9, Issue:1

    Topics: 5-Hydroxytryptophan; Amino Acids; Carbidopa; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleaceti

1979
The use of 5-hydroxytryptophan in a child with Lesch-Nyhan syndrome.
    Child psychiatry and human development, 1976,Winter, Volume: 7, Issue:2

    Topics: 5-Hydroxytryptophan; Child, Preschool; Cold Temperature; Crying; Dopamine beta-Hydroxylase; Dose-Res

1976
Relationship between autotomy behaviour and spinal cord monoaminergic levels in rats.
    Pain, 1992, Volume: 48, Issue:3

    Topics: Animals; Behavior, Animal; Biogenic Monoamines; Dopamine; Hydroxyindoleacetic Acid; Male; Neurons, A

1992
The effect of tryptophan supplementation on autotomy induced by nerve lesions in rats.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 40, Issue:2

    Topics: Animals; Behavior, Animal; Brain Chemistry; Denervation; Hydroxyindoleacetic Acid; Neurons, Afferent

1991
Biological correlations of suicide and aggressivity in major depressions (with melancholia): 5-hydroxyindoleacetic acid and cortisol in cerebral spinal fluid, dexamethasone suppression test and therapeutic response to 5-hydroxytryptophan.
    Neuropsychobiology, 1985, Volume: 14, Issue:2

    Topics: 5-Hydroxytryptophan; Adult; Aggression; Bipolar Disorder; Carbidopa; Depressive Disorder; Dexamethas

1985
The serotonin hypothesis of (auto)aggression. Critical appraisal of the evidence.
    Annals of the New York Academy of Sciences, 1986, Volume: 487

    Topics: Aggression; Brain; Depressive Disorder; Hostility; Humans; Hydroxyindoleacetic Acid; Lesch-Nyhan Syn

1986
Cerebrospinal fluid correlates of suicide attempts and aggression.
    Annals of the New York Academy of Sciences, 1986, Volume: 487

    Topics: Aggression; Animals; Bipolar Disorder; Depressive Disorder; Homovanillic Acid; Humans; Hydroxyindole

1986
Lesch-Nyhan syndrome: a study of motor behavior and cerebrospinal fluid neurotransmitters.
    Annals of neurology, 1988, Volume: 23, Issue:5

    Topics: Carbidopa; Catecholamines; Child; Child, Preschool; Fluphenazine; Glycols; Homovanillic Acid; Humans

1988