hydroxyindoleacetic acid has been researched along with Autosomal Dominant Juvenile Parkinson Disease in 19 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Behavioral deficits at the end of the 14-day dosing regime and on day 28 (i." | 1.42 | Noradrenergic and serotonergic neurochemistry arising from intranasal inoculation with α-synuclein aggregates which incite parkinsonian-like symptoms. ( Davydova, TV; Fomina, VG; Gruden, MA; Kudrin, VS; Morozova-Roche, LA; Narkevich, VB; Sewell, RD; Wang, C, 2015) |
| "Treatment with idazoxan counteracted the observed Parkinsonian behaviour in 6-OHDA-lesioned rats and increased the spontaneous open-field activity in control rats." | 1.32 | The effect of the alpha2-adrenoreceptor antagonist idazoxan against 6-hydroxydopamine-induced Parkinsonism in rats: multiple facets of action? ( Schmidt, WJ; Srinivasan, J, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 10 (52.63) | 29.6817 |
| 2010's | 7 (36.84) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Kaiserova, M | 1 |
| Chudackova, M | 1 |
| Prikrylova Vranova, H | 1 |
| Mensikova, K | 1 |
| Kastelikova, A | 1 |
| Stejskal, D | 1 |
| Kanovsky, P | 1 |
| Gruden, MA | 1 |
| Davydova, TV | 1 |
| Narkevich, VB | 1 |
| Fomina, VG | 1 |
| Wang, C | 1 |
| Kudrin, VS | 1 |
| Morozova-Roche, LA | 1 |
| Sewell, RD | 1 |
| Santiago, RM | 1 |
| Tonin, FS | 1 |
| Barbiero, J | 1 |
| Zaminelli, T | 1 |
| Boschen, SL | 1 |
| Andreatini, R | 1 |
| Da Cunha, C | 2 |
| Lima, MM | 2 |
| Vital, MA | 2 |
| Dupre, KB | 1 |
| Eskow, KL | 1 |
| Steiniger, A | 1 |
| Klioueva, A | 1 |
| Negron, GE | 1 |
| Lormand, L | 1 |
| Park, JY | 1 |
| Bishop, C | 1 |
| Boulet, S | 1 |
| Mounayar, S | 1 |
| Poupard, A | 1 |
| Bertrand, A | 1 |
| Jan, C | 1 |
| Pessiglione, M | 1 |
| Hirsch, EC | 1 |
| Feuerstein, C | 1 |
| François, C | 1 |
| Féger, J | 1 |
| Savasta, M | 1 |
| Tremblay, L | 1 |
| Nowak, P | 1 |
| Kostrzewa, RA | 1 |
| Skaba, D | 1 |
| Kostrzewa, RM | 1 |
| Kurian, MA | 1 |
| Li, Y | 1 |
| Zhen, J | 1 |
| Meyer, E | 1 |
| Hai, N | 1 |
| Christen, HJ | 1 |
| Hoffmann, GF | 1 |
| Jardine, P | 1 |
| von Moers, A | 1 |
| Mordekar, SR | 1 |
| O'Callaghan, F | 1 |
| Wassmer, E | 1 |
| Wraige, E | 1 |
| Dietrich, C | 1 |
| Lewis, T | 1 |
| Hyland, K | 1 |
| Heales, S | 2 |
| Sanger, T | 1 |
| Gissen, P | 1 |
| Assmann, BE | 1 |
| Reith, ME | 1 |
| Maher, ER | 1 |
| Chao, OY | 2 |
| Huston, JP | 2 |
| von Bothmer, A | 1 |
| Pum, ME | 2 |
| Moreira, CG | 1 |
| Barbiero, JK | 1 |
| Ariza, D | 1 |
| Dombrowski, PA | 1 |
| Sabioni, P | 1 |
| Bortolanza, M | 1 |
| Mattern, C | 1 |
| Silva, AM | 1 |
| Wessler, J | 1 |
| Ruocco, LA | 1 |
| Nikolaus, S | 1 |
| Ricaurte, GA | 1 |
| Yuan, J | 1 |
| Hatzidimitriou, G | 1 |
| Cord, BJ | 1 |
| McCann, UD | 1 |
| Foster, SB | 1 |
| Wrona, MZ | 1 |
| Han, J | 1 |
| Dryhurst, G | 1 |
| Srinivasan, J | 2 |
| Schmidt, WJ | 2 |
| Crawley, F | 1 |
| Rudge, P | 1 |
| Diepold, K | 1 |
| Schütz, B | 1 |
| Rostasy, K | 1 |
| Wilken, B | 1 |
| Hougaard, P | 1 |
| Güttler, F | 1 |
| Romstad, A | 1 |
| Birk Møller, L | 1 |
| Struve, MF | 1 |
| McManus, BE | 1 |
| Wong, BA | 1 |
| Dorman, DC | 1 |
| Nagamitsu, S | 1 |
| Matsuishi, T | 1 |
| Yamashita, Y | 1 |
| Yamada, S | 1 |
| Kato, H | 1 |
| Abe, K | 1 |
| Taguchi, K | 1 |
| Wasai, T | 1 |
| Ren, J | 1 |
| Utsunomiya, I | 1 |
| Shinohara, T | 1 |
| Miyatake, T | 1 |
| Sano, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Cerebral Autoregulation in Patients With Aneurysmal SubArachnoid Haemorrhage[NCT03987139] | 45 participants (Anticipated) | Interventional | 2019-06-15 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
19 other studies available for hydroxyindoleacetic acid and Autosomal Dominant Juvenile Parkinson Disease
| Article | Year |
|---|---|
Cerebrospinal Fluid Levels of 5-Hydroxyindoleacetic Acid in Parkinson's Disease and Atypical Parkinsonian Syndromes.
Topics: Diagnosis, Differential; Humans; Hydroxyindoleacetic Acid; Multiple System Atrophy; Parkinson Diseas | 2021 |
Noradrenergic and serotonergic neurochemistry arising from intranasal inoculation with α-synuclein aggregates which incite parkinsonian-like symptoms.
Topics: Administration, Intranasal; alpha-Synuclein; Amyloid; Animals; Hydroxyindoleacetic Acid; Male; Mice; | 2015 |
The nonsteroidal antiinflammatory drug piroxicam reverses the onset of depressive-like behavior in 6-OHDA animal model of Parkinson's disease.
Topics: Anhedonia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Depressive Disor | 2015 |
Effects of coincident 5-HT1A receptor stimulation and NMDA receptor antagonism on L-DOPA-induced dyskinesia and rotational behaviors in the hemi-parkinsonian rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Corpus Striatum; Di | 2008 |
Behavioral recovery in MPTP-treated monkeys: neurochemical mechanisms studied by intrastriatal microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Chlorocebus aethiops; Corpus Striatum; Di | 2008 |
Acute L: -DOPA effect on hydroxyl radical- and DOPAC-levels in striatal microdialysates of parkinsonian rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Corpus Striatum; Disease Models, Anim | 2010 |
Clinical and molecular characterisation of hereditary dopamine transporter deficiency syndrome: an observational cohort and experimental study.
Topics: Brain; Cell Line, Transformed; Child; Child, Preschool; Cohort Studies; Dopamine Plasma Membrane Tra | 2011 |
Chronic progesterone treatment of male rats with unilateral 6-hydroxydopamine lesion of the dorsal striatum exacerbates [corrected] parkinsonian symptoms.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Res | 2011 |
Behavioral, neurochemical and histological alterations promoted by bilateral intranigral rotenone administration: a new approach for an old neurotoxin.
Topics: Animals; Avoidance Learning; Disease Models, Animal; Dopaminergic Neurons; Exploratory Behavior; Hyd | 2012 |
Intranasally applied L-DOPA alleviates parkinsonian symptoms in rats with unilateral nigro-striatal 6-OHDA lesions.
Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Intranasal; Amphetamine; Analysis of Variance; Anima | 2012 |
RETRACTED: Severe dopaminergic neurotoxicity in primates after a common recreational dose regimen of MDMA ("ecstasy").
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Autoradiography; Axons; Brain; Carrier Proteins; Corpus Str | 2002 |
The parkinsonian neurotoxin 1-methyl-4-phenylpyridinium (MPP(+)) mediates release of l-3,4-dihydroxyphenylalanine (l-DOPA) and inhibition of l-DOPA decarboxylase in the rat striatum: a microdialysis study.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Antioxidants; Aromatic Amino Acid Decarboxylase Inhibitors; Bo | 2003 |
The effect of the alpha2-adrenoreceptor antagonist idazoxan against 6-hydroxydopamine-induced Parkinsonism in rats: multiple facets of action?
Topics: Adrenergic alpha-Antagonists; Animals; Antiparkinson Agents; Brain; Catalepsy; Disease Models, Anima | 2004 |
Treatment with alpha2-adrenoceptor antagonist, 2-methoxy idazoxan, protects 6-hydroxydopamine-induced Parkinsonian symptoms in rats: neurochemical and behavioral evidence.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Brain Chemistry; Catalepsy; Disease Mod | 2004 |
Reversible parkinsonism following heroin pyrolysate inhalation is associated with tetrahydrobiopterin deficiency.
Topics: Adult; Biopterins; Brain; Brain Diseases, Metabolic; Electroencephalography; Epilepsy; Female; Heroi | 2004 |
Levodopa-responsive infantile parkinsonism due to a novel mutation in the tyrosine hydroxylase gene and exacerbation by viral infections.
Topics: Animals; Antiparkinson Agents; Central Nervous System Viral Diseases; Child, Preschool; DNA Mutation | 2005 |
Basal ganglia neurotransmitter concentrations in rhesus monkeys following subchronic manganese sulfate inhalation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Basal Ganglia; Disease Models, Animal; Dopamine; gamma-Amin | 2007 |
Extrapontine myelinolysis with parkinsonism after rapid correction of hyponatremia: high cerebrospinal fluid level of homovanillic acid and successful dopaminergic treatment.
Topics: Antiparkinson Agents; Basal Ganglia; Child; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic A | 1999 |
Stereoselective effect of (R)- and (S)-1-methyl-1,2,3,4-tetrahydroisoquinolines on a mouse model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbidopa; Cell Count; Disease Models, Animal; Dopamine; Do | 2001 |