Page last updated: 2024-10-21

hydroxyindoleacetic acid and Antisocial Behavior

hydroxyindoleacetic acid has been researched along with Antisocial Behavior in 18 studies

(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.

Antisocial Behavior: Behavior that sharply deviates from social norms and violates rights of others

Research Excerpts

ExcerptRelevanceReference
"Associations in 52 normal individuals were examined between plasma and cerebrospinal fluid (CSF) concentrations of tryptophan (Trp) and tyrosine, and concentrations of monoamine metabolites in the CSF, and scores on an aggression questionnaire, the Kinsey Institute Reaction List II, and the Eysenck Personality Questionnaire."3.69Aggression and personality: association with amino acids and monoamine metabolites. ( Alling, C; Bennicke, K; Breum, L; Bøge-Rasmussen, T; Jensen, C; Larsen, OG; Mortensen, EL; Møller, SE, 1996)
"The relationship between genetic liability for antisocial behavior and CSF 5-hydroxyindoleacetic acid (5-HIAA) in newborns was explored."3.69CSF 5-HIAA and family history of antisocial personality disorder in newborns. ( Constantino, JN; Morris, JA; Murphy, DL, 1997)
"In an earlier, separate study, the authors found that human aggression and suicide (a specific aggression-related behavior) were associated with lower levels of CSF 5-hydroxyindoleacetic acid (5-HIAA), a serotonin metabolite."3.66Aggression, suicide, and serotonin: relationships to CSF amine metabolites. ( Brown, GL; Bunney, WE; Ebert, MH; Goodwin, FK; Goyer, PF; Jimerson, DC; Klein, WJ, 1982)
"Definition, understanding, and treatment of antisocial personality disorder continue to present difficulties, but there have been several encouraging developments."2.37The antisocial personality: a review. ( Reid, WH, 1985)
"Family history of antisocial personality disorder predicted significantly lower scores for soothability (p = ."1.30Family psychiatric history, cerebrospinal fluid monoamine metabolites, and temperament in infants. ( Constantino, JN; Morris, JA; Murphy, DL, 1999)
"Alcoholic, impulsive offenders with antisocial personality disorder had low mean cerebrospinal fluid (CSF) 5-hydroxyindoleacetic acid (5-HIAA) and corticotropin levels and high mean CSF testosterone concentrations."1.29CSF biochemistries, glucose metabolism, and diurnal activity rhythms in alcoholic, violent offenders, fire setters, and healthy volunteers. ( Bissette, G; Guidotti, A; Kalogeras, K; Karonen, SL; Linnoila, M; Nemeroff, C; Poland, RE; Rawlings, R; Tokola, R; Virkkunen, M, 1994)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19908 (44.44)18.7374
1990's7 (38.89)18.2507
2000's3 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Soderstrom, H2
Blennow, K2
Sjodin, AK1
Forsman, A2
Virkkunen, M5
Rissanen, A1
Naukkarinen, H1
Franssila-Kallunki, A1
Linnoila, M7
Tiihonen, J1
Brown, GL1
Ebert, MH1
Goyer, PF1
Jimerson, DC1
Klein, WJ1
Bunney, WE1
Goodwin, FK2
Shashkova, NG1
Avanesova, TS1
Scheinin, M1
Nuutila, A1
Rimon, R1
Rawlings, R2
Tokola, R2
Poland, RE1
Guidotti, A1
Nemeroff, C1
Bissette, G1
Kalogeras, K1
Karonen, SL1
Nielsen, DA1
Goldman, D1
Andrianova, EP1
Drozdov, AZ1
Zhukovskaia, ED1
Kukanova, MM1
Morozova, GV1
Naumovich, AO1
Kogan, BM1
Møller, SE1
Mortensen, EL1
Breum, L1
Alling, C1
Larsen, OG1
Bøge-Rasmussen, T1
Jensen, C1
Bennicke, K1
Higley, JD1
Suomi, SJ1
Constantino, JN2
Morris, JA2
Murphy, DL2
Manhem, A1
Zabrodin, GD1
Turova, ZG1
Reid, WH1
Roy, A2
Guthrie, S1
Griffiths, AW1
Marks, V1
Fry, D1
Morley, G1
Lewis, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Pimavanserin on Aggression and Social Cognition.[NCT05895513]Phase 235 participants (Anticipated)Interventional2024-01-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for hydroxyindoleacetic acid and Antisocial Behavior

ArticleYear
The antisocial personality: a review.
    Hospital & community psychiatry, 1985, Volume: 36, Issue:8

    Topics: Adolescent; Aggression; Antisocial Personality Disorder; Behavior Therapy; Child; Child Development;

1985

Other Studies

17 other studies available for hydroxyindoleacetic acid and Antisocial Behavior

ArticleYear
New evidence for an association between the CSF HVA:5-HIAA ratio and psychopathic traits.
    Journal of neurology, neurosurgery, and psychiatry, 2003, Volume: 74, Issue:7

    Topics: Adolescent; Adult; Age of Onset; Aggression; Antisocial Personality Disorder; Attention Deficit Diso

2003
Energy substrate metabolism among habitually violent alcoholic offenders having antisocial personality disorder.
    Psychiatry research, 2007, Apr-15, Volume: 150, Issue:3

    Topics: Adult; Alcoholism; Antisocial Personality Disorder; Calorimetry; Carbohydrates; Cholesterol; Diagnos

2007
Aggression, suicide, and serotonin: relationships to CSF amine metabolites.
    The American journal of psychiatry, 1982, Volume: 139, Issue:6

    Topics: Adolescent; Adult; Aggression; Antisocial Personality Disorder; Borderline Personality Disorder; Bra

1982
[Metabolism of biogenic amines in hysterical neuroses, hysterical personality development and hysterical psychopathy].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1982, Volume: 82, Issue:11

    Topics: Acetylcholine; Adult; Antisocial Personality Disorder; Asthenia; Biogenic Amines; Cholinesterases; F

1982
Low cerebrospinal fluid 5-hydroxyindoleacetic acid concentration differentiates impulsive from nonimpulsive violent behavior.
    Life sciences, 1983, Dec-26, Volume: 33, Issue:26

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adolescent; Adult; Antisocial Personality Disorder; Compulsive Behav

1983
CSF biochemistries, glucose metabolism, and diurnal activity rhythms in alcoholic, violent offenders, fire setters, and healthy volunteers.
    Archives of general psychiatry, 1994, Volume: 51, Issue:1

    Topics: Adrenocorticotropic Hormone; Adult; Alcoholism; Antisocial Personality Disorder; Circadian Rhythm; D

1994
Suicidality and 5-hydroxyindoleacetic acid concentration associated with a tryptophan hydroxylase polymorphism.
    Archives of general psychiatry, 1994, Volume: 51, Issue:1

    Topics: Adult; Alcoholism; Antisocial Personality Disorder; Disruptive, Impulse Control, and Conduct Disorde

1994
[Various components of the serotonin system in depressive disorders in psychopathic personalities].
    Biulleten' eksperimental'noi biologii i meditsiny, 1994, Volume: 117, Issue:3

    Topics: Adolescent; Adult; Antisocial Personality Disorder; Blood Platelets; Depressive Disorder; Humans; Hy

1994
Aggression and personality: association with amino acids and monoamine metabolites.
    Psychological medicine, 1996, Volume: 26, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aggression; Amino Acids; Antisocial Personality Disorder; Blood-Brai

1996
A nonhuman primate model of type II alcoholism? Part 2. Diminished social competence and excessive aggression correlates with low cerebrospinal fluid 5-hydroxyindoleacetic acid concentrations.
    Alcoholism, clinical and experimental research, 1996, Volume: 20, Issue:4

    Topics: Adult; Age Factors; Aggression; Alcohol Drinking; Alcoholism; Animals; Antisocial Personality Disord

1996
CSF 5-HIAA and family history of antisocial personality disorder in newborns.
    The American journal of psychiatry, 1997, Volume: 154, Issue:12

    Topics: Adult; Antisocial Personality Disorder; Family; Female; Humans; Hydroxyindoleacetic Acid; Infant, Ne

1997
Family psychiatric history, cerebrospinal fluid monoamine metabolites, and temperament in infants.
    Biological psychiatry, 1999, Mar-01, Volume: 45, Issue:5

    Topics: Antisocial Personality Disorder; Genetic Variation; Homovanillic Acid; Humans; Hydroxyindoleacetic A

1999
CSF studies in violent offenders. I. 5-HIAA as a negative and HVA as a positive predictor of psychopathy.
    Journal of neural transmission (Vienna, Austria : 1996), 2001, Volume: 108, Issue:7

    Topics: Adolescent; Adult; Aged; Antisocial Personality Disorder; Crime; Female; Homovanillic Acid; Humans;

2001
[Differences in serotonin and dopamine metabolism in psychopathy and sluggish schizophrenia].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1976, Volume: 76, Issue:11

    Topics: Adult; Antisocial Personality Disorder; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Aci

1976
Indices of serotonin and glucose metabolism in violent offenders, arsonists, and alcoholics.
    Annals of the New York Academy of Sciences, 1986, Volume: 487

    Topics: Alcoholism; Antisocial Personality Disorder; Blood Glucose; Disruptive, Impulse Control, and Conduct

1986
CSF studies on alcoholism and related behaviours.
    Progress in neuro-psychopharmacology & biological psychiatry, 1989, Volume: 13, Issue:3-4

    Topics: Alcoholism; Antisocial Personality Disorder; Gambling; Humans; Hydroxyindoleacetic Acid; Personality

1989
Prisoners of XYY constitution: biochemical studies.
    The British journal of psychiatry : the journal of mental science, 1972, Volume: 121, Issue:563

    Topics: Adult; Antisocial Personality Disorder; Blood Glucose; Body Height; Cholesterol; Chromosome Aberrati

1972