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hydroxyindoleacetic acid and Anoxemia

hydroxyindoleacetic acid has been researched along with Anoxemia in 36 studies

(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.

Research Excerpts

ExcerptRelevanceReference
"Long-term hypoxia induces changes in neuropeptide-Y-like immunoreactivity (NPY-LI) and/or in the content of serotonin (5-HT) and its metabolite 5-hydroxyindoleacetic acid (5-HIAA) at the central level."7.70Effects of carotid sinus nerve transection on changes in neuropeptide Y and indolamines induced by long-term hypoxia in rats. ( Dalmaz, Y; Denoroy, L; Pequignot, JM; Poncet, L, 1998)
"The effects of cinepazide, a vasodilator, on the content, biosynthesis and turnover of noradrenaline (NA), dopamine (DA) and 5-hydroxytryptamine (5-HT) in the rat brain were examined under room air and hypoxia (10% O2, 90% N2)."7.67The effects of cinepazide on the content, biosynthesis and turnover of noradrenaline, dopamine and 5-hydroxytryptamine in the rat brain under room air and hypoxia. ( Fujiwara, M; Lee, K; Miwa, S, 1986)
" Compared with wild-type mice, SM22-5-HTT(+) mice showed depressed hypoxic pulmonary vasoconstriction contrasting with greater severity of hypoxia- or monocrotaline-induced PH."3.73Transgenic mice overexpressing the 5-hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension. ( Adnot, S; Barlier-Mur, AM; Eddahibi, S; Guignabert, C; Hamon, M; Hanoun, N; Izikki, M; Li, Z; Rodman, D; Tu, LI; Zadigue, P, 2006)
"Long-term hypoxia induces changes in neuropeptide-Y-like immunoreactivity (NPY-LI) and/or in the content of serotonin (5-HT) and its metabolite 5-hydroxyindoleacetic acid (5-HIAA) at the central level."3.70Effects of carotid sinus nerve transection on changes in neuropeptide Y and indolamines induced by long-term hypoxia in rats. ( Dalmaz, Y; Denoroy, L; Pequignot, JM; Poncet, L, 1998)
"To determine whether sustained hypoxia alters daily rhythms in brain and pituitary neurotransmitters, the daily variations in vasoactive intestinal peptide-like immunoreactivity (VIP-LI), neuropeptide Y-like immunoreactivity (NPY-LI), serotonin (5-HT), and 5-hydroxyindole-3-acetic acid (5-HIAA) content were determined in discrete brain regions, pineal gland and anterior pituitary of hypoxic (10% O(2); 14 days) and normoxic rats."3.70Altered daily rhythms of brain and pituitary indolamines and neuropeptides in long-term hypoxic rats. ( Cottet-Emard, JM; Dalmaz, Y; Denoroy, L; Pequignot, JM; Poncet, L, 1999)
"The influence of long-term hypoxia (10% O2, 14 days) on in vivo activity of tryptophan hydroxylase and on 5-hydroxytryptamine (5-HT) and 5-hydroxyindoleacetic acid (5-HIAA) concentration in discrete brain regions of rats was assessed."3.69Activity of tryptophan hydroxylase and content of indolamines in discrete brain regions after a long-term hypoxic exposure in the rat. ( Dalmaz, Y; Denoroy, L; Pequignot, JM; Poncet, L, 1997)
"The effects of cinepazide, a vasodilator, on the content, biosynthesis and turnover of noradrenaline (NA), dopamine (DA) and 5-hydroxytryptamine (5-HT) in the rat brain were examined under room air and hypoxia (10% O2, 90% N2)."3.67The effects of cinepazide on the content, biosynthesis and turnover of noradrenaline, dopamine and 5-hydroxytryptamine in the rat brain under room air and hypoxia. ( Fujiwara, M; Lee, K; Miwa, S, 1986)
" Hypoxia caused a decrease of the striatal levels of homovanillic acid (HVA), dihydroxy 3-4 phenylacetic acid (DOPAC) [inhibition of tyrosine hydroxylase (TH) and monoamine oxidase (MAO)] and 3-methoxytyramine (3 MT) (inhibition of release)."3.67Dynamic characteristics of dopamine, norepinephrine and serotonin metabolism in axonal endings of the rat hypothalamus and striatum during hypoxia: a study using HPLC with electrochemical detection. ( Boismare, F; Chretien, P; Daoust, M; Moore, N; Saligaut, C, 1986)
"The concentrations of 3-methoxy-4-hydroxyphenylglycol (MHPG), 5-hydroxyindole-3-acetic acid (5-HIAA) and homovanillic acid (HVA) were determined in CSF of patients with hypoxia due to circulatory arrest."3.67Biogenic amine metabolites in human CSF after hypoxia due to cardiac arrest. ( Kärkelä, J; Marnela, KM; Odink, J; Thissen, JT, 1989)
"Three patients with postanoxic intention myoclonus, two patients with intention tremor, and one patient with cerebral palsy were administered L-5-hydroxytryptophan (L-5HTP), the precursor of serotonin, in combination with MK 486, a peripheral amino acid decarboxylase inhibitor."3.65Therapy of intention myoclonus with L-5-hydroxytryptophan and a peripheral decarboxylase inhibitor, MK 486. ( Sethy, VH; Van Woert, MH, 1975)
"Sudden infant death syndrome (SIDS) is postulated to result from abnormalities in brainstem control of autonomic function and breathing during a critical developmental period."1.36Brainstem serotonergic deficiency in sudden infant death syndrome. ( Belliveau, RA; Borenstein, NS; Duncan, JR; Haas, EA; Hoffman, JM; Kinney, HC; Krous, HF; Mokler, DJ; Nattie, EE; Paterson, DS; Stanley, C; Trachtenberg, FL, 2010)
"Vannucci, Experimental biology of cerebral hypoxia-ischemia: relation to perinatal brain damage, Pediatr."1.30Anoxic and hypoxic immature rat model for measurement of monoamine using in vivo microdialysis. ( Ishida, A; Nakajima, W; Takada, G, 1999)
"During anoxia, the level of the inhibitory transmitter gamma-aminobutyric acid (GABA) increased (2."1.28Changes in turtle brain neurotransmitters and related substances during anoxia. ( Alfaro, AA; Lutz, PL; Nilsson, GE, 1990)
"Posthypoxic action myoclonus is usually associated with impaired serotonin (5-HT) neurotransmission but in some patients 5-HT precursors aggravate and 5-HT blockers improve action myoclonus."1.27Clinical, biochemical, and pharmacological observation in a patient with postasphyxic myoclonus: association to serotonin hyperactivity. ( De Yebenes, JG; Giménez-Roldán, S; Mateo, D; Muradas, V, 1988)
"Postanoxic myoclonus was first accepted as being related to a dysfunction of the ventrolateral thalamic nucleus."1.26Postanoxic myoclonus. Treatment of a case with 5-hydroxytryptophane and a decarboxylase inhibitor. ( Beretta, E; de Crousaz, G; Regli, F; Steck, AJ, 1981)
"In two patients with postanoxic action myoclonus, L-tryptophan or a monoamine oxidase inhibitor induced a moderate improvement, but L-5-hydroxytryptophan had greater therapeutic effect."1.26Beneficial effects of serotonin precursors in postanoxic action myoclonus. ( De Léan, J; Hornykiewicz, O; Richardson, JC, 1976)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199024 (66.67)18.7374
1990's8 (22.22)18.2507
2000's2 (5.56)29.6817
2010's2 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Karpova, IV1
Mikheev, VV1
Marysheva, VV1
Kuritcyna, NA1
Bychkov, ER1
Shabanov, PD1
Duncan, JR1
Paterson, DS1
Hoffman, JM1
Mokler, DJ1
Borenstein, NS1
Belliveau, RA1
Krous, HF1
Haas, EA1
Stanley, C1
Nattie, EE1
Trachtenberg, FL1
Kinney, HC1
Guignabert, C1
Izikki, M1
Tu, LI1
Li, Z1
Zadigue, P1
Barlier-Mur, AM1
Hanoun, N1
Rodman, D1
Hamon, M1
Adnot, S1
Eddahibi, S1
Thomas, P1
Rahman, MS1
Khan, IA1
Kummer, JA1
Beretta, E1
Regli, F1
de Crousaz, G1
Steck, AJ1
Hedner, T1
Lundborg, P1
Silverstein, F1
Johnston, MV2
Poncet, L3
Denoroy, L3
Dalmaz, Y3
Pequignot, JM3
Nakajima, W1
Ishida, A1
Takada, G1
Cottet-Emard, JM1
Van Woert, MH2
Sethy, VH1
De Léan, J2
Richardson, JC2
Hornykiewicz, O1
Steinberg, H2
Bassett, DJ1
Fisher, AB2
Gordon, K1
Statman, D1
Robinson, TE1
Becker, JB1
Silverstein, FS1
Nilsson, GE2
Hadjiconstantinou, M1
Yates, AJ1
Neff, NH1
Alfaro, AA1
Lutz, PL1
Rosenbaum, D1
Chung, EY1
Chadwick, D1
Hallett, M1
Jenner, P1
Marsden, CD1
Fahn, S1
Rewcastle, NB1
Freeman, GB1
Nielsen, P1
Gibson, GE1
Miwa, S2
Fujiwara, M4
Lee, K2
Saligaut, C1
Chretien, P1
Daoust, M1
Moore, N1
Boismare, F1
MacMillan, V1
Pouliot, T1
de la Noüe, J1
Roberge, AG1
Giménez-Roldán, S1
Mateo, D1
Muradas, V1
De Yebenes, JG1
Burnstock, G1
Lincoln, J1
Fehér, E1
Hopwood, AM1
Kirkpatrick, K1
Milner, P1
Ralevic, V1
Odink, J1
Kärkelä, J1
Thissen, JT1
Marnela, KM1
Davis, JN1
Carlsson, A1
Vaĭsfel'd, IL1
Il'icheva, RF1
Kassil', GN1
Bassett, D1
Lowy, PH1
Keighley, G1
Cohen, NS1
van Dyke, DH1
Cserr, H1
Barlow, CF1

Other Studies

36 other studies available for hydroxyindoleacetic acid and Anoxemia

ArticleYear
[Central monoaminergic systems sensitivity to acute hypoxia with hypercapnia changes after the maintenance under the long-term social isolation].
    Biomeditsinskaia khimiia, 2018, Volume: 64, Issue:6

    Topics: Animals; Brain; Brain Chemistry; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Hypercapnia;

2018
Brainstem serotonergic deficiency in sudden infant death syndrome.
    JAMA, 2010, Feb-03, Volume: 303, Issue:5

    Topics: Autopsy; Brain Stem; Case-Control Studies; Female; Humans; Hydroxyindoleacetic Acid; Hypoxia; Infant

2010
Transgenic mice overexpressing the 5-hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension.
    Circulation research, 2006, May-26, Volume: 98, Issue:10

    Topics: Acute Disease; Animals; Blood Pressure; Blood Vessels; Humans; Hydroxyindoleacetic Acid; Hypertensio

2006
Widespread endocrine disruption and reproductive impairment in an estuarine fish population exposed to seasonal hypoxia.
    Proceedings. Biological sciences, 2007, Nov-07, Volume: 274, Issue:1626

    Topics: Animals; Ecosystem; Female; Gonadotropin-Releasing Hormone; Hydroxyindoleacetic Acid; Hypoxia; Lutei

2007
Postanoxic myoclonus. Treatment of a case with 5-hydroxytryptophane and a decarboxylase inhibitor.
    Journal of neurology, 1981, Volume: 225, Issue:1

    Topics: 5-Hydroxytryptophan; Benserazide; Humans; Hydrazines; Hydroxyindoleacetic Acid; Hypoxia; Male; Middl

1981
5-HIAA Levels in brain and cerebrospinal fluid of the neonatal rat during oxygen deprivation.
    Neuroscience letters, 1980, Oct-02, Volume: 19, Issue:3

    Topics: Animals; Animals, Newborn; Brain Chemistry; Hydroxyindoleacetic Acid; Hypoxia; Monoamine Oxidase; Ra

1980
Effects of hypoxia-ischemia on monoamine metabolism in the immature brain.
    Annals of neurology, 1984, Volume: 15, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Behavior, Animal; Biogenic Amines; Corpus

1984
Activity of tryptophan hydroxylase and content of indolamines in discrete brain regions after a long-term hypoxic exposure in the rat.
    Brain research, 1997, Aug-08, Volume: 765, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Brain Chemistry;

1997
Effects of carotid sinus nerve transection on changes in neuropeptide Y and indolamines induced by long-term hypoxia in rats.
    Pflugers Archiv : European journal of physiology, 1998, Volume: 437, Issue:1

    Topics: Animals; Brain; Carotid Sinus; Chemoreceptor Cells; Corpus Striatum; Denervation; Frontal Lobe; Hydr

1998
Anoxic and hypoxic immature rat model for measurement of monoamine using in vivo microdialysis.
    Brain research. Brain research protocols, 1999, Volume: 3, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Brain; Brain Chemistry; Brain Ischemia; C

1999
Altered daily rhythms of brain and pituitary indolamines and neuropeptides in long-term hypoxic rats.
    The American journal of physiology, 1999, Volume: 277, Issue:1

    Topics: Animals; Brain; Brain Chemistry; Circadian Rhythm; Hydroxyindoleacetic Acid; Hypoxia; Male; Neuropep

1999
Therapy of intention myoclonus with L-5-hydroxytryptophan and a peripheral decarboxylase inhibitor, MK 486.
    Neurology, 1975, Volume: 25, Issue:2

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Cer

1975
Beneficial effects of serotonin precursors in postanoxic action myoclonus.
    Neurology, 1976, Volume: 26, Issue:9

    Topics: 5-Hydroxytryptophan; Aged; Carbidopa; Female; Humans; Hydroxyindoleacetic Acid; Hypoxia; Levodopa; M

1976
Metabolic requirements for 5-hydroxytryptamine uptake by the isolated lung.
    Chest, 1975, Volume: 67, Issue:2 Suppl

    Topics: Animals; Biological Transport, Active; Cyanides; Deoxyglucose; Glucose; Guinea Pigs; Hydroxyindoleac

1975
Transient hypoxia alters striatal catecholamine metabolism in immature brain: an in vivo microdialysis study.
    Journal of neurochemistry, 1990, Volume: 54, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Brain Diseases; Corpus Striatum; Dialysis

1990
Turnover of serotonin in brain of an anoxia-tolerant vertebrate, the crucian carp.
    The American journal of physiology, 1990, Volume: 258, Issue:6 Pt 2

    Topics: 5-Hydroxytryptophan; Animals; Brain; Carps; Cyprinidae; Hydrazines; Hydroxyindoleacetic Acid; Hypoxi

1990
Hypoxia-induced neurotransmitter deficits in neonatal rats are partially corrected by exogenous GM1 ganglioside.
    Journal of neurochemistry, 1990, Volume: 55, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Animals; Animals, Newborn; Brain; Choline; Corpus Str

1990
Changes in turtle brain neurotransmitters and related substances during anoxia.
    The American journal of physiology, 1990, Volume: 259, Issue:2 Pt 2

    Topics: Amino Acids; Animals; Brain; Dopamine; Hydroxyindoleacetic Acid; Hypoxia; Neurotransmitter Agents; S

1990
Biochemistry and therapeutics of posthypoxic myoclonus.
    Advances in neurology, 1986, Volume: 43

    Topics: 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Aspartic Acid; Benzodiazepines; Carbidopa; Electro

1986
Treatment of posthypoxic action myoclonus: implications for the pathophysiology of the disorder.
    Advances in neurology, 1986, Volume: 43

    Topics: 5-Hydroxytryptophan; Benzodiazepines; Clonazepam; Female; Fenclonine; Humans; Hydroxyindoleacetic Ac

1986
Newer drugs for posthypoxic action myoclonus: observations from a well-studied case.
    Advances in neurology, 1986, Volume: 43

    Topics: Clonazepam; Drug Therapy, Combination; Estrogens, Conjugated (USP); Fasting; Female; Humans; Hydroxy

1986
Pathological findings in a case of hypoxic myoclonus treated with 5-hydroxytryptophan and a decarboxylase inhibitor.
    Advances in neurology, 1986, Volume: 43

    Topics: 5-Hydroxytryptophan; Aged; Brain; Carbidopa; Diazepam; Electroencephalography; Female; Fenclonine; H

1986
Monoamine neurotransmitter metabolism and locomotor activity during chemical hypoxia.
    Journal of neurochemistry, 1986, Volume: 46, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxyindole

1986
The effects of cinepazide on the content, biosynthesis and turnover of noradrenaline, dopamine and 5-hydroxytryptamine in the rat brain under room air and hypoxia.
    Japanese journal of pharmacology, 1986, Volume: 41, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Brain; Dihydroxyphenylalanine; Dopamine; Hydroxyindoleacetic Acid; Hyd

1986
Dynamic characteristics of dopamine, norepinephrine and serotonin metabolism in axonal endings of the rat hypothalamus and striatum during hypoxia: a study using HPLC with electrochemical detection.
    Methods and findings in experimental and clinical pharmacology, 1986, Volume: 8, Issue:6

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Axons; Chromatography, High Pressure Liquid; Corpus Striatu

1986
Effect of probenecid on cerebral and cisternal cerebrospinal fluid lactate content.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1987, Volume: 7, Issue:1

    Topics: Animals; Brain; Cisterna Magna; Energy Metabolism; Glucose; Homovanillic Acid; Hydroxyindoleacetic A

1987
Determination of serotonin turnover in the rat brain using 6-fluorotryptophan.
    Journal of neurochemistry, 1987, Volume: 48, Issue:5

    Topics: Animals; Brain; Hydroxyindoleacetic Acid; Hypoxia; Male; Probenecid; Rats; Rats, Inbred Strains; Ser

1987
Influence of diet and hypoxia on brain serotonin and catecholamines in rainbow trout (Salmo gairdneri).
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1988, Volume: 89, Issue:1

    Topics: Animals; Brain; Catecholamines; Dietary Proteins; Dopamine; Hydroxyindoleacetic Acid; Hypoxia; Norep

1988
Clinical, biochemical, and pharmacological observation in a patient with postasphyxic myoclonus: association to serotonin hyperactivity.
    Clinical neuropharmacology, 1988, Volume: 11, Issue:2

    Topics: 5-Hydroxytryptophan; Aged; Humans; Hydroxyindoleacetic Acid; Hypoxia; Male; Methysergide; Myoclonus;

1988
Serotonin is localized in endothelial cells of coronary arteries and released during hypoxia: a possible new mechanism for hypoxia-induced vasodilatation of the rat heart.
    Experientia, 1988, Aug-15, Volume: 44, Issue:8

    Topics: Animals; Coronary Vessels; Endothelium, Vascular; Hydroxyindoleacetic Acid; Hypoxia; Immunoenzyme Te

1988
Biogenic amine metabolites in human CSF after hypoxia due to cardiac arrest.
    Acta neurologica Scandinavica, 1989, Volume: 80, Issue:1

    Topics: Aged; Aged, 80 and over; Biogenic Amines; Female; Glycols; Heart Arrest; Homovanillic Acid; Humans;

1989
The effect of hypoxia on monoamine synthesis, levels and metabolism in rat brain.
    Journal of neurochemistry, 1973, Volume: 21, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Brain; Dihydroxyphenylalanine; Dopamine; Fluorometry;

1973
[The diurnal rhythm of biogenic amines in man under normal conditions and in hypoxia].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1974, Volume: 60, Issue:10

    Topics: Adult; Aerospace Medicine; Amine Oxidase (Copper-Containing); Circadian Rhythm; Diuresis; Female; Hi

1974
Energy utilization by the lung.
    The American journal of medicine, 1974, Volume: 57, Issue:3

    Topics: Adenosine Triphosphate; Aerobiosis; Anaerobiosis; Animals; Capillaries; Carbon Radioisotopes; Cyanid

1974
Stimulation by serotonin of erythropoietin-dependent erythropoiesis in mice.
    British journal of haematology, 1970, Volume: 19, Issue:6

    Topics: 5-Hydroxytryptophan; Animals; Epinephrine; Erythropoiesis; Erythropoietin; Female; Hematocrit; Hemog

1970
5-Hydroxyindoleacetic acid (5-HIAA) transport by isolated choroid plexus.
    Neurology, 1970, Volume: 20, Issue:4

    Topics: Aminohippuric Acids; Anesthesia; Animals; Biological Transport, Active; Carbon Isotopes; Choroid Ple

1970