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hydroxyindoleacetic acid and Anorexia

hydroxyindoleacetic acid has been researched along with Anorexia in 21 studies

(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.

Anorexia: The lack or loss of APPETITE accompanied by an aversion to food and the inability to eat. It is the defining characteristic of the disorder ANOREXIA NERVOSA.

Research Excerpts

ExcerptRelevanceReference
" In an effort to determine whether indoleamine systems had any role in the etiology of cancer anorexia the anorectic effects of cancer (Walker 256 carcinosarcoma) were investigated in immature female rats that had been depleted of brain serotonin (5-HT) by the intracisternal injection of 5,7-dihydroxytryptamine (5,7-DHT) or the systemic injection of para-chloramphetamine (PCA)."7.66Serotonin depletion by 5,7-dihydroxytryptamine or para-chloroamphetamine does not affect cancer anorexia. ( Chance, WT; Fischer, JE; von Meyenfeldt, M, 1983)
"In vivo 5-HT release and regional hypothalamic 5-HT and tryptophan concentrations were measured in rats with 2,4,6,-trinitrobenzene sulfonic acid (TNBS)-induced colitis, healthy controls, and animals pair-fed to match the food intake of the colitic group."3.70The role of medial hypothalamic serotonin in the suppression of feeding in a rat model of colitis. ( Ballinger, A; Dryden, S; El-Haj, T; Farthing, MJ; Obeid, O; Perrett, D; Turvill, J; Williams, G, 2000)
"Whether in tumor-bearing rats a temporal relationship exists between an increase in plasma free tryptophan (FTRP), an increase in brain serotonin (5-HT), and onset of anorexia was studied."3.69Mechanism of early tumor anorexia. ( Beverly, JL; Cangiano, C; Meguid, MM; Muscaritoli, M; Rossi-Fanelli, F; Yang, ZJ, 1996)
" In an effort to determine whether indoleamine systems had any role in the etiology of cancer anorexia the anorectic effects of cancer (Walker 256 carcinosarcoma) were investigated in immature female rats that had been depleted of brain serotonin (5-HT) by the intracisternal injection of 5,7-dihydroxytryptamine (5,7-DHT) or the systemic injection of para-chloramphetamine (PCA)."3.66Serotonin depletion by 5,7-dihydroxytryptamine or para-chloroamphetamine does not affect cancer anorexia. ( Chance, WT; Fischer, JE; von Meyenfeldt, M, 1983)
"Analysis of indole amine metabolism within acute (Walker 256 carcinosarcoma) and chronic (methycholanthrene-induced sarcoma) animal models of cancer anorexia demonstrated elevated levels of plasma free tryptophan, whole brain tryptophan, serotonin and 5-hydroxyindoleacetic acid in anorectic tumor-bearing rats."3.66Changes in brain amines associated with cancer anorexia. ( Chance, WT; Fischer, JE; von Meyenfeldt, MF, 1983)
" In the current study, we evaluated the effects of chronic administration of low doses of IAPP on satiety-related neurotransmitters and neuropeptides in the hypothalamus, hippocampus, striatum, left cortex, and right cortex of the rat."1.31Effects of long-term infusion of anorexic concentrations of islet amyloid polypeptide on neurotransmitters and neuropeptides in rat brain. ( Adrian, TE; Arnelo, U; Ding, X; Herrington, MK; Larsson, J; Marcusson, J; Permert, J; Reidelberger, R; Strömmer, L; Theodorsson, E, 2000)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199010 (47.62)18.7374
1990's8 (38.10)18.2507
2000's2 (9.52)29.6817
2010's1 (4.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dwarkasing, JT1
Witkamp, RF1
Boekschoten, MV1
Ter Laak, MC1
Heins, MS1
van Norren, K1
von Meyenfeldt, M2
Chance, WT5
Fischer, JE5
Berlatzky, Y1
Stinnett, JD1
Trocki, O1
Alexander, JW1
Nichols, M1
Maickel, RP1
Yim, GK1
von Meyenfeldt, MF1
Thomas, I1
Pelleymounter, MA1
Cullen, MJ1
Wellman, CL1
Martinez, M1
Arnalich, F1
Vazquez, JJ1
Hernanz, A1
Muscaritoli, M2
Meguid, MM1
Beverly, JL1
Yang, ZJ1
Cangiano, C2
Rossi-Fanelli, F2
Currie, PJ1
Coscina, DV1
Fletcher, PJ1
Haleem, DJ1
Jabeen, B1
Parveen, T1
Ballinger, A1
El-Haj, T1
Perrett, D1
Turvill, J1
Obeid, O1
Dryden, S1
Williams, G1
Farthing, MJ1
Arnelo, U1
Herrington, MK1
Theodorsson, E1
Adrian, TE1
Reidelberger, R1
Larsson, J1
Marcusson, J1
Strömmer, L1
Ding, X1
Permert, J1
Samanin, R1
Bendotti, C1
Candelaresi, G1
Garattini, S1
Bitar, MS1
Keis, AF1
Owusu, SE1
Mulven, R1
DeSouza, EB1
Ceci, F1
Cairella, M1
Cascino, A1
Del Ben, M1
Laviano, A1
Hyman, SL2
Coyle, JT1
Parke, JC1
Porter, C1
Thomas, GH1
Jankel, W1
Batshaw, ML2
Porter, CA1
Page, TJ1
Iwata, BA1
Kissel, R1
Gietzen, DW1
Rogers, QR1
Leung, PM1
Semon, B1
Piechota, T1
Yamamoto, M1
Ujike, H1
Ogawa, N1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Daily Supplementation of 5-HTP on Body Composition, a Randomized Investigation[NCT05216406]65 participants (Actual)Interventional2021-01-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for hydroxyindoleacetic acid and Anorexia

ArticleYear
Effects of 5-hydroxytryptophan on eating behavior and adherence to dietary prescriptions in obese adult subjects.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: 5-Hydroxytryptophan; Adult; Anorexia; Diet, Reducing; Dietary Carbohydrates; Feeding Behavior; Femal

1991

Other Studies

20 other studies available for hydroxyindoleacetic acid and Anorexia

ArticleYear
Increased hypothalamic serotonin turnover in inflammation-induced anorexia.
    BMC neuroscience, 2016, 05-20, Volume: 17, Issue:1

    Topics: Animals; Anorexia; Cell Line; Cytokines; Disease Models, Animal; Eating; Gene Expression Profiling;

2016
Correlation of changes in brain indoleamine metabolism with onset of anorexia in rats.
    American journal of surgery, 1982, Volume: 143, Issue:1

    Topics: Animals; Anorexia; Brain; Feeding and Eating Disorders; Humans; Hydroxyindoleacetic Acid; Male; Rats

1982
Analysis of brain indoleamines and catecholamines associated with burn-induced anorexia.
    The Journal of trauma, 1982, Volume: 22, Issue:10

    Topics: Amino Acids; Animals; Anorexia; Body Weight; Brain Chemistry; Burns; Dopamine; Feeding and Eating Di

1982
Serotonin depletion by 5,7-dihydroxytryptamine or para-chloroamphetamine does not affect cancer anorexia.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 18, Issue:1

    Topics: 5,7-Dihydroxytryptamine; Amphetamines; Animals; Anorexia; Body Weight; Brain; Carcinoma 256, Walker;

1983
Increased central serotonergic activity associated with nocturnal anorexia induced by Walker 256 carcinoma.
    Life sciences, 1983, Apr-18, Volume: 32, Issue:16

    Topics: Animals; Anorexia; Brain; Carcinoma 256, Walker; Circadian Rhythm; Eating; Feeding and Eating Disord

1983
Changes in brain amines associated with cancer anorexia.
    Neuroscience and biobehavioral reviews, 1983,Winter, Volume: 7, Issue:4

    Topics: Amino Acids; Animals; Anorexia; Brain; Brain Mapping; Cachexia; Carcinoma 256, Walker; Dopamine; Fee

1983
Insulin reverses ammonia-induced anorexia and experimental cancer anorexia.
    Nutrition and cancer, 1994, Volume: 21, Issue:3

    Topics: Ammonia; Animals; Anorexia; Blood Glucose; Dopamine; Eating; Glucagon; Hydroxyindoleacetic Acid; Hyp

1994
Characteristics of BDNF-induced weight loss.
    Experimental neurology, 1995, Volume: 131, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Anorexia; Appetite Depressants; Brain-Derived Neurotrophic

1995
Altered cerebrospinal fluid amino acid pattern in the anorexia of aging: relationship with biogenic amine metabolism.
    Life sciences, 1993, Volume: 53, Issue:21

    Topics: Aged; Aged, 80 and over; Aging; Amino Acids; Anorexia; Biogenic Amines; Body Weight; Female; Homovan

1993
Mechanism of early tumor anorexia.
    The Journal of surgical research, 1996, Feb-01, Volume: 60, Issue:2

    Topics: Amino Acids; Animals; Anorexia; Brain Chemistry; Eating; Hydroxyindoleacetic Acid; Male; Neoplasms,

1996
Reversal of fenfluramine and fluoxetine anorexia by 8-OH-DPAT is attenuated following raphe injection of 5,7-dihydroxytryptamine.
    Brain research, 1998, Jul-27, Volume: 800, Issue:1

    Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anorexia; Brain; Corpus St

1998
Inhibition of restraint-induced anorexia by injected tryptophan.
    Life sciences, 1998, Volume: 63, Issue:14

    Topics: Animals; Anorexia; Brain Chemistry; Eating; Hydroxyindoleacetic Acid; Male; Rats; Rats, Wistar; Rest

1998
The role of medial hypothalamic serotonin in the suppression of feeding in a rat model of colitis.
    Gastroenterology, 2000, Volume: 118, Issue:3

    Topics: Amino Acids; Animals; Anorexia; Colitis; Drinking; Eating; Fenclonine; Hydroxyindoleacetic Acid; Hyp

2000
Effects of long-term infusion of anorexic concentrations of islet amyloid polypeptide on neurotransmitters and neuropeptides in rat brain.
    Brain research, 2000, Dec-29, Volume: 887, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amyloid; Animals; Anorexia; Biogenic Monoamines; Blood Glucose; Brai

2000
Specificity of serotoninergic involvement in the decrease of food intake induced by quipazine in the rat.
    Life sciences, 1977, Nov-01, Volume: 21, Issue:9

    Topics: Animals; Anorexia; Brain; Corpus Striatum; Dose-Response Relationship, Drug; Feeding and Eating Diso

1977
Impairment of albuterol-induced suppression of food intake in diabetes mellitus.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 41, Issue:3

    Topics: Albuterol; Animals; Anorexia; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Eat

1992
Anorexia and altered serotonin metabolism in a patient with argininosuccinic aciduria.
    The Journal of pediatrics, 1986, Volume: 108, Issue:5 Pt 1

    Topics: Amino Acid Metabolism, Inborn Errors; Anorexia; Arginine; Argininosuccinic Acid; Child; Dietary Prot

1986
Behavior management of feeding disturbances in urea cycle and organic acid disorders.
    The Journal of pediatrics, 1987, Volume: 111, Issue:4

    Topics: Adult; Amino Acid Metabolism, Inborn Errors; Anorexia; Argininosuccinic Acid; Behavior Therapy; Chil

1987
Serotonin and feeding responses of rats to amino acid imbalance: initial phase.
    The American journal of physiology, 1987, Volume: 253, Issue:5 Pt 2

    Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amino Acids; Animals; Anorexia; Die

1987
Metoclopramide-induced parkinsonism.
    Clinical neuropharmacology, 1987, Volume: 10, Issue:3

    Topics: Aged; Aged, 80 and over; Anorexia; Gastritis; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; M

1987