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hydroxyindoleacetic acid and Anankastic Personality

hydroxyindoleacetic acid has been researched along with Anankastic Personality in 24 studies

(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.

Research Excerpts

ExcerptRelevanceReference
"Concentrations of the serotonin metabolite 5-hydroxyindoleacetic acid (5-HIAA), the dopamine metabolite homovanillic acid, and the noradrenaline metabolite 4-hydroxy-3-methoxyphenyl glycol were measured in CSF before and after three weeks' treatment of severe obsessive-compulsive disorder with clomipramine hydrochloride."9.05Clomipramine treatment of obsessive-compulsive disorder. II. Biochemical aspects. ( Asberg, M; Bertilsson, L; Mellström, B; Sjöqvist, F; Thorén, P; Träskman, L, 1980)
"The CSF levels of corticotropin-releasing hormone, vasopressin, somatostatin, and oxytocin and of the monoamine metabolites 5-hydroxyindoleacetic acid, homovanillic acid, and 3-methoxy-4-hydroxyphenylglycol were measured in 17 children and adolescents with obsessive-compulsive disorder before and after long-term treatment with clomipramine."7.69Changes in cerebrospinal fluid neurochemistry during treatment of obsessive-compulsive disorder with clomipramine. ( Altemus, M; Leonard, HL; Potter, WZ; Rapoport, JL; Richter, D; Rubinow, DR; Swedo, SE, 1994)
"Limited neurobiological data have implicated central arginine vasopressin in the pathobiology of obsessive-compulsive disorder (OCD)."7.69Elevated cerebrospinal fluid levels of oxytocin in obsessive-compulsive disorder. Comparison with Tourette's syndrome and healthy controls. ( Anderson, GM; Chappell, PB; Goodman, WK; Leckman, JF; McDougle, CJ; McSwiggan-Hardin, M; North, WG; Pauls, DL; Price, LH; Riddle, MA, 1994)
"Concentrations of the serotonin metabolite 5-hydroxyindoleacetic acid (5-HIAA), the dopamine metabolite homovanillic acid, and the noradrenaline metabolite 4-hydroxy-3-methoxyphenyl glycol were measured in CSF before and after three weeks' treatment of severe obsessive-compulsive disorder with clomipramine hydrochloride."5.05Clomipramine treatment of obsessive-compulsive disorder. II. Biochemical aspects. ( Asberg, M; Bertilsson, L; Mellström, B; Sjöqvist, F; Thorén, P; Träskman, L, 1980)
"The CSF levels of corticotropin-releasing hormone, vasopressin, somatostatin, and oxytocin and of the monoamine metabolites 5-hydroxyindoleacetic acid, homovanillic acid, and 3-methoxy-4-hydroxyphenylglycol were measured in 17 children and adolescents with obsessive-compulsive disorder before and after long-term treatment with clomipramine."3.69Changes in cerebrospinal fluid neurochemistry during treatment of obsessive-compulsive disorder with clomipramine. ( Altemus, M; Leonard, HL; Potter, WZ; Rapoport, JL; Richter, D; Rubinow, DR; Swedo, SE, 1994)
"Limited neurobiological data have implicated central arginine vasopressin in the pathobiology of obsessive-compulsive disorder (OCD)."3.69Elevated cerebrospinal fluid levels of oxytocin in obsessive-compulsive disorder. Comparison with Tourette's syndrome and healthy controls. ( Anderson, GM; Chappell, PB; Goodman, WK; Leckman, JF; McDougle, CJ; McSwiggan-Hardin, M; North, WG; Pauls, DL; Price, LH; Riddle, MA, 1994)
"In light of prior data that the central administration of vasopressin in animals is associated with abnormal persistence of behaviors acquired under aversive conditioning, we studied the secretion of arginine vasopressin into the cerebrospinal fluid and plasma in patients with obsessive-compulsive disorder and controls."3.68Abnormalities in the regulation of vasopressin and corticotropin releasing factor secretion in obsessive-compulsive disorder. ( Altemus, M; Demitrack, M; Dubbert, B; Gold, PW; Kalogeras, KT; Murphy, DL; Pigott, T, 1992)
"Tourette syndrome patients with high levels of obsessive-compulsive symptoms were compared with patients without these symptoms on urinary measures of serotonin and its major metabolite, 5-hydroxyindoleacetic acid (5HIAA)."3.68Urinary indoleamines in Tourette syndrome patients with obsessive-compulsive characteristics. ( Baker, GB; Bornstein, RA, 1992)
"Cerebrospinal fluid levels of 5-hydroxyindoleacetic acid, a metabolite of serotonin, were measured in relation to aggression, impulsivity, and social functioning in 29 children and adolescents with disruptive behavior disorders."3.68Cerebrospinal fluid monoamine metabolites, aggression, and impulsivity in disruptive behavior disorders of children and adolescents. ( Brown, GL; Hamburger, S; Hibbs, E; Kruesi, MJ; Lenane, M; Potter, WZ; Rapoport, JL, 1990)
"Depression was by far the most important factor."1.26Cortisol in the CSF of depressed and suicidal patients. ( Asberg, M; Bertilsson, L; Lantto, O; Schalling, D; Träskman, L; Tybring, G, 1980)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199012 (50.00)18.7374
1990's10 (41.67)18.2507
2000's2 (8.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Markianos, M1
Lafazanos, S1
Koutsis, G1
Sfagos, C1
Seretis, A1
Barbarich, N1
Träskman, L2
Tybring, G1
Asberg, M2
Bertilsson, L2
Lantto, O1
Schalling, D1
Thorén, P1
Mellström, B1
Sjöqvist, F1
Insel, TR2
Murphy, DL4
Lieberman, J1
Altemus, M2
Swedo, SE4
Leonard, HL3
Richter, D1
Rubinow, DR2
Potter, WZ5
Rapoport, JL5
Leckman, JF2
Goodman, WK2
North, WG1
Chappell, PB1
Price, LH1
Pauls, DL1
Anderson, GM2
Riddle, MA2
McSwiggan-Hardin, M1
McDougle, CJ1
de Groot, CM1
Bornstein, RA2
Baker, GB2
Sasaki, K1
Miyakawa, M1
Sudo, T1
Yoshizaki, F1
Bridges, PK1
Bartlett, JR1
Sepping, P1
Kantamaneni, BD1
Curzon, G1
Kruesi, MJ5
Rettew, DC1
Listwak, SJ1
Berrettini, W1
Stipetic, M2
Hamburger, S2
Gold, PW2
Pigott, T1
Kalogeras, KT1
Demitrack, M1
Dubbert, B1
Hibbs, E1
Lenane, M1
Brown, GL1
Hardin, MT1
Swedo, S1
Leonard, H1
Mueller, EA1
Alterman, I1
Linnoila, M1
Hamburger, SD2
Cheslow, DL1
Papeschi, R1
Molina-Negro, P1
Sourkes, TL1
Erba, G1
Baker, M1
Goodwin, FK1
Miller, H1
Kotin, J1
Bunney, WE1
Coppen, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00004325]200 participants Observational1988-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for hydroxyindoleacetic acid and Anankastic Personality

ArticleYear
The psychopharmacological treatment of obsessive-compulsive disorder: a review.
    Journal of clinical psychopharmacology, 1981, Volume: 1, Issue:5

    Topics: Anti-Anxiety Agents; Antipsychotic Agents; Clinical Trials as Topic; Clomipramine; Double-Blind Meth

1981

Trials

4 trials available for hydroxyindoleacetic acid and Anankastic Personality

ArticleYear
Clomipramine treatment of obsessive-compulsive disorder. II. Biochemical aspects.
    Archives of general psychiatry, 1980, Volume: 37, Issue:11

    Topics: Adult; Clomipramine; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Met

1980
The psychopharmacological treatment of obsessive-compulsive disorder: a review.
    Journal of clinical psychopharmacology, 1981, Volume: 1, Issue:5

    Topics: Anti-Anxiety Agents; Antipsychotic Agents; Clinical Trials as Topic; Clomipramine; Double-Blind Meth

1981
Obsessive-compulsive disorder and serotonin: is there a connection?
    Biological psychiatry, 1985, Volume: 20, Issue:11

    Topics: Adult; Blood Platelets; Central Nervous System; Clinical Trials as Topic; Desipramine; Female; Human

1985
L-tryptophan in affective disorders: indoleamine changes and differential clinical effects.
    Psychopharmacologia, 1974, Jan-09, Volume: 34, Issue:1

    Topics: Affective Symptoms; Blood Platelets; Clinical Trials as Topic; Depression; Humans; Hydroxyindoleacet

1974

Other Studies

20 other studies available for hydroxyindoleacetic acid and Anankastic Personality

ArticleYear
CSF neurotransmitter metabolites and neuropsychiatric symptomatology in patients with normal pressure hydrocephalus.
    Clinical neurology and neurosurgery, 2009, Volume: 111, Issue:3

    Topics: Aged; Aged, 80 and over; Analysis of Variance; Chromatography, High Pressure Liquid; Dopamine; Femal

2009
Is there a common mechanism of serotonin dysregulation in anorexia nervosa and obsessive compulsive disorder?
    Eating and weight disorders : EWD, 2002, Volume: 7, Issue:3

    Topics: Anorexia Nervosa; Comorbidity; Diagnosis, Differential; Family Health; Humans; Hydroxyindoleacetic A

2002
Cortisol in the CSF of depressed and suicidal patients.
    Archives of general psychiatry, 1980, Volume: 37, Issue:7

    Topics: Adjustment Disorders; Clomipramine; Depression; Female; Homovanillic Acid; Humans; Hydrocortisone; H

1980
Evidence for a biological hypothesis of obsessive-compulsive disorder.
    Neuropsychobiology, 1984, Volume: 11, Issue:1

    Topics: Adolescent; Antidepressive Agents, Tricyclic; Depressive Disorder; Dexamethasone; Diseases in Twins;

1984
Changes in cerebrospinal fluid neurochemistry during treatment of obsessive-compulsive disorder with clomipramine.
    Archives of general psychiatry, 1994, Volume: 51, Issue:10

    Topics: Adolescent; Child; Clomipramine; Corticotropin-Releasing Hormone; Female; Homovanillic Acid; Humans;

1994
Elevated cerebrospinal fluid levels of oxytocin in obsessive-compulsive disorder. Comparison with Tourette's syndrome and healthy controls.
    Archives of general psychiatry, 1994, Volume: 51, Issue:10

    Topics: Adolescent; Adult; Age of Onset; Arginine Vasopressin; Biogenic Amines; Comorbidity; Dynorphins; Fam

1994
Obsessive-compulsive symptom clusters and urinary amine correlates in Tourette syndrome.
    The Journal of nervous and mental disease, 1995, Volume: 183, Issue:4

    Topics: Adolescent; Biogenic Amines; Child; Dopamine; Factor Analysis, Statistical; Female; Humans; Hydroxyi

1995
[Evaluation of marble burying behavior: induced alteration of monoamine metabolism in mouse brain].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1997, Volume: 110, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Brain; Disease Models, Animal; Dopamin

1997
Precursors and metabolites of 5-hydroxytryptamine and dopamine in the ventricular cerebrospinal fluid of psychiatric patients.
    Psychological medicine, 1976, Volume: 6, Issue:3

    Topics: Adult; Aged; Anxiety Disorders; Brain Diseases; Cerebral Ventricles; Depression; Female; Homovanilli

1976
Cerebrospinal fluid neurochemistry in children and adolescents with obsessive-compulsive disorder.
    Archives of general psychiatry, 1992, Volume: 49, Issue:1

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Arginine Vasopressin; Child; Clomipramine; Corticotr

1992
Abnormalities in the regulation of vasopressin and corticotropin releasing factor secretion in obsessive-compulsive disorder.
    Archives of general psychiatry, 1992, Volume: 49, Issue:1

    Topics: Adolescent; Adult; Aged; Arginine Vasopressin; Corticotropin-Releasing Hormone; Female; Homovanillic

1992
Urinary indoleamines in Tourette syndrome patients with obsessive-compulsive characteristics.
    Psychiatry research, 1992, Volume: 41, Issue:3

    Topics: Adolescent; Child; Female; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Indoles; Male; Obse

1992
Cerebrospinal fluid monoamine metabolites, aggression, and impulsivity in disruptive behavior disorders of children and adolescents.
    Archives of general psychiatry, 1990, Volume: 47, Issue:5

    Topics: Adolescent; Age Factors; Aggression; Attention Deficit Disorder with Hyperactivity; Child; Child Beh

1990
Low CSF 5HIAA and obsessions of violence: report of two cases.
    Psychiatry research, 1990, Volume: 33, Issue:1

    Topics: Aggression; Female; Humans; Hydroxyindoleacetic Acid; Male; Obsessive-Compulsive Disorder; Thinking;

1990
CSF somatostatin in childhood psychiatric disorders: a preliminary investigation.
    Psychiatry research, 1990, Volume: 33, Issue:3

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorders; Depressi

1990
Childhood obsessive compulsive disorder.
    Journal of child psychology and psychiatry, and allied disciplines, 1986, Volume: 27, Issue:3

    Topics: Adolescent; Anorexia Nervosa; Behavior Therapy; Child; Child, Preschool; Clomipramine; Epilepsy, Tem

1986
Concentration gradient of CSF monoamine metabolites in children and adolescents.
    Biological psychiatry, 1988, Volume: 24, Issue:5

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorders; Child De

1988
Lack of seasonal variation in pediatric lumbar cerebrospinal fluid neurotransmitter metabolite concentrations.
    Acta psychiatrica Scandinavica, 1989, Volume: 80, Issue:6

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorders; Female;

1989
The concentration of homovanillic and 5-hydroxyindoleacetic acids in ventricular and lumbar CSF. Studies in patients with extrapyramidal disorders, epilepsy, and other diseases.
    Neurology, 1972, Volume: 22, Issue:11

    Topics: Adolescent; Adult; Basal Ganglia Diseases; Cerebral Palsy; Cerebral Ventricles; Diazepam; Dihydroxyp

1972
Indoleamines and affective disorders.
    Journal of psychiatric research, 1972, Volume: 9, Issue:3

    Topics: Affective Symptoms; Brain Chemistry; Central Nervous System; Depression; Electroconvulsive Therapy;

1972