hydroxyindoleacetic acid has been researched along with Allodynia in 6 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic pain was evaluated by thermal hyperalgesia in Hargreaves test and mechanical allodynia in von Frey test, depressive-like behaviors were evaluated by immobility time in forced swim test and tail suspension test." | 1.48 | Chronic trans-astaxanthin treatment exerts antihyperalgesic effect and corrects co-morbid depressive like behaviors in mice with chronic pain. ( Ding, L; Jiang, X; Jing, C; Liu, F; Pang, C; Yan, Q; Zhang, L, 2018) |
| "Wild-type mice reproducibly developed thermal hyperalgesia and paw edema for 5 days after CFA injection." | 1.37 | 5-hydroxyindolacetic acid (5-HIAA), a main metabolite of serotonin, is responsible for complete Freund's adjuvant-induced thermal hyperalgesia in mice. ( Chen, Y; Gerlach, M; Lesch, KP; Moessner, R; Palm, F; Sommer, C, 2011) |
| "In conclusion, OLETF rats showed thermal hyperalgesia and disturbed responses to thermal pain, and an alteration of 5-HT function might have a role in this disturbance." | 1.33 | Disturbance of response to acute thermal pain in naturally occurring cholecystokinin-a receptor gene knockout Otsuka Long-Evans Tokushima Fatty (OLETF) rats. ( Funakoshi, A; Kanai, S; Kaneko, T; Miyasaka, K; Nomoto, S; Ohta, M; Tahara, S, 2006) |
| "5-HTT-/- mice did not develop thermal hyperalgesia, but showed bilateral mechanical allodynia after the nerve injury." | 1.32 | Absence of thermal hyperalgesia in serotonin transporter-deficient mice. ( Gerlach, M; Heinemann, T; Lesch, KP; Mössner, R; Murphy, DL; Riederer, P; Sommer, C; Vogel, C, 2003) |
| "The possibility is discussed that the hyperalgesia noted above results from a permanently reduced turnover of brain serotonin produced by halothane present in brain at days 10-15 of gestation." | 1.26 | Behavioral and neurochemical effects of prenatal halothane. ( Bowman, RE; Smith, RF, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Munawar, N | 1 |
| Bitar, MS | 1 |
| Masocha, W | 1 |
| Jiang, X | 1 |
| Yan, Q | 1 |
| Liu, F | 1 |
| Jing, C | 1 |
| Ding, L | 1 |
| Zhang, L | 1 |
| Pang, C | 1 |
| Chen, Y | 1 |
| Palm, F | 1 |
| Lesch, KP | 2 |
| Gerlach, M | 2 |
| Moessner, R | 1 |
| Sommer, C | 2 |
| Vogel, C | 1 |
| Mössner, R | 1 |
| Heinemann, T | 1 |
| Murphy, DL | 1 |
| Riederer, P | 1 |
| Miyasaka, K | 1 |
| Nomoto, S | 1 |
| Ohta, M | 1 |
| Kanai, S | 1 |
| Kaneko, T | 1 |
| Tahara, S | 1 |
| Funakoshi, A | 1 |
| Bowman, RE | 1 |
| Smith, RF | 1 |
6 other studies available for hydroxyindoleacetic acid and Allodynia
| Article | Year |
|---|---|
Activation of 5-HT1A Receptors Normalizes the Overexpression of Presynaptic 5-HT1A Receptors and Alleviates Diabetic Neuropathic Pain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, | 2023 |
Chronic trans-astaxanthin treatment exerts antihyperalgesic effect and corrects co-morbid depressive like behaviors in mice with chronic pain.
Topics: Analgesics; Animals; Behavior, Animal; Chronic Pain; Cytokines; Depression; Hydroxyindoleacetic Acid | 2018 |
5-hydroxyindolacetic acid (5-HIAA), a main metabolite of serotonin, is responsible for complete Freund's adjuvant-induced thermal hyperalgesia in mice.
Topics: Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Fenclonine; Freund's Adjuvant; Hydr | 2011 |
Absence of thermal hyperalgesia in serotonin transporter-deficient mice.
Topics: Adrenal Glands; Animals; Behavior, Animal; Carrier Proteins; Disease Models, Animal; Hindlimb; Hot T | 2003 |
Disturbance of response to acute thermal pain in naturally occurring cholecystokinin-a receptor gene knockout Otsuka Long-Evans Tokushima Fatty (OLETF) rats.
Topics: Acute Disease; Animals; Cerebral Cortex; Corpus Striatum; Dopamine; Hippocampus; Hydroxyindoleacetic | 2006 |
Behavioral and neurochemical effects of prenatal halothane.
Topics: Abnormalities, Drug-Induced; Animals; Behavior, Animal; Brain; Dopamine; Environmental Exposure; Fem | 1977 |