Page last updated: 2024-10-21

hydroxyindoleacetic acid and Alkaptonuria

hydroxyindoleacetic acid has been researched along with Alkaptonuria in 1 studies

(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.

Alkaptonuria: An inborn error of amino acid metabolism resulting from a defect in the enzyme HOMOGENTISATE 1,2-DIOXYGENASE, an enzyme involved in the breakdown of PHENYLALANINE and TYROSINE. It is characterized by accumulation of HOMOGENTISIC ACID in the urine, OCHRONOSIS in various tissues, and ARTHRITIS.

Research Excerpts

ExcerptRelevanceReference
"BDI-II scores were significantly higher following 24 months of nitisinone therapy in patients that were followed up, however the majority of these patients remained in the minimal category of depression."7.88Clinical and biochemical assessment of depressive symptoms in patients with Alkaptonuria before and after two years of treatment with nitisinone. ( Davison, AS; Devine, J; Gallagher, JA; Harrold, JA; Hughes, AT; Hughes, G; J C G, H; Khedr, M; Milan, AM; Norman, BP; Ranganath, LR; Usher, J, 2018)
"BDI-II scores were significantly higher following 24 months of nitisinone therapy in patients that were followed up, however the majority of these patients remained in the minimal category of depression."3.88Clinical and biochemical assessment of depressive symptoms in patients with Alkaptonuria before and after two years of treatment with nitisinone. ( Davison, AS; Devine, J; Gallagher, JA; Harrold, JA; Hughes, AT; Hughes, G; J C G, H; Khedr, M; Milan, AM; Norman, BP; Ranganath, LR; Usher, J, 2018)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davison, AS1
Harrold, JA1
Hughes, G1
Norman, BP1
Devine, J1
Usher, J1
Hughes, AT1
Khedr, M1
Gallagher, JA1
Milan, AM1
J C G, H1
Ranganath, LR1

Other Studies

1 other study available for hydroxyindoleacetic acid and Alkaptonuria

ArticleYear
Clinical and biochemical assessment of depressive symptoms in patients with Alkaptonuria before and after two years of treatment with nitisinone.
    Molecular genetics and metabolism, 2018, Volume: 125, Issue:1-2

    Topics: Adolescent; Adult; Aged; Alkaptonuria; Cyclohexanones; Depression; Dopamine; Female; Humans; Hydroxy

2018